PRMT5/EGFR-IN-1
Ref. TM-T209477
Product Information
Name:PRMT5/EGFR-IN-1
Brand:Targetmol
Description:PRMT5/EGFR-IN-1 (Compound 10p) is an orally active dual inhibitor targeting PRMT5 and EGFR, with IC50 values of 15.47 μM and 19.31 μM, respectively. It demonstrates antiproliferative activity against the A549, MCF7, HeLa, and MDA-MB-231 cell lines. This compound also exhibits favorable pharmacokinetic (PK) and pharmacodynamic (PD) properties in vivo and significantly inhibits the growth of MCF7 orthotopic xenograft tumors.
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Chemical properties
Molecular weight:520.15855
Formula:C27H22F6N2O2
Technical inquiry about: PRMT5/EGFR-IN-1
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