LDN-193189 2HCl
CAS: 1435934-00-1
Ref. TM-T35348
| 5mg | 72.00 € | ||
| 10mg | 94.00 € | ||
| 25mg | 143.00 € | ||
| 50mg | 220.00 € | ||
| 100mg | 328.00 € | ||
| 500mg | 782.00 € | ||
| 1ml*10 (DMSO) | 86.00 € |
Product Information
- LDN-193189 2HCl, DM-3189 2HCl
LDN-193189 2HCl (DM-3189 2HCl) is a selective BMP signaling inhibitor that inhibits ALK1,ALK2,ALK3 and ALK6, showing IC50s of 0.8 nM, 0.8 nM, 5.3 nM, and 16.7 nM, respectively, in kinase assays.LDN-193189 2HCl inhibited the transcriptional activity of BMP type I receptors in C2C12 cells, with IC50s of 5 nM and 30 nM, respectively. LDN-193189 2HCl inhibited the transcriptional activity of BMP type I receptors ALK2 and ALK3 in C2C12 cells, with IC50s of 5 nM and 30 nM, respectively, and was 200-fold more selective for BMP than for TGF-β.
Chemical properties
Technical inquiry about: TM-T35348 LDN-193189 2HCl
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