Product Information
Name:F44-A13
Brand:Targetmol
Description:F44-A13 is an orally active, highly selective farnesoid X receptor (FXR) antagonist with an IC50 value of 1.1 μM. It optimizes cholesterol metabolism and reduces activity by inducing CYP7A1 expression, lowering cholesterol, triglycerides, and low-density lipoprotein cholesterol (LDL-C) levels in mouse models. F44-A13 is applicable for studying metabolic diseases associated with lipid disorders [1].
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Chemical properties
Molecular weight:544.71
Formula:C28H40N4O5S
Technical inquiry about: F44-A13
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