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MJ04

CAS:

Ref. TM-T87974

MJ04
Targetmol

Product Information

Name:MJ04
Brand:Targetmol
Description:MJ04 is a selective inhibitor of Janus Kinase 3 (JAK3) with an IC50 of 2.03 nM. It hinders T cell differentiation and suppresses pro-inflammatory cytokines in macrophages induced by Lipopolysaccharides. In mice, MJ04 exhibits favorable pharmacokinetic properties and promotes hair growth in a DHT-induced alopecia model in athymic mice, without notable toxicity (LD50>2 g/kg).
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Chemical properties

Molecular weight:345.37
Formula:C20H16FN5
Color/Form:Solid

Technical inquiry about: MJ04

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