Product Information
Name:PROTAC EGFR degrader 11
Brand:Targetmol
Description:PROTAC EGFR degrader 11 (Compound B71) is a PROTAC degrader targeting the epidermal growth factor receptor (EGFR), with a DC50 of less than 100 nM. It binds to CRBN-DDB1 with a Ki of 36 nM. This compound effectively degrades EGFR, focal adhesion kinase (FAK), and RSK1, and inhibits the proliferation of BaF3 wild-type and EGFR mutant cells, exhibiting an IC50 of less than 100 nM.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:991.61
Formula:C49H64ClFN10O7S
Color/Form:Solid
Technical inquiry about: PROTAC EGFR degrader 11
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