Product Information
Name:PROTAC EGFR degrader 10
Brand:Targetmol
Description:PROTAC EGF Rdegrader 10 (Compound B56) is a PROTAC degrader targeting the epidermal growth factor receptor (EGFR) with a DC50 of less than 100 nM. It binds to CRBN-DDB1 with a Ki of 37 nM and degrades EGFR, focal adhesion kinase (FAK), and RSK1, inhibiting the proliferation of BaF3 wild-type and EGFR mutants with an IC50 of less than 150 nM.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:973.62
Formula:C49H65ClN10O7S
Color/Form:Solid
Technical inquiry about: PROTAC EGFR degrader 10
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