Estimated delivery in United States, on Friday 28 Feb 2025
Product Information
Name:
Neptinib
Synonyms:
- NEP010
Description:
Neptinib (NEP010), a derivative of Afatinib, exhibits enhanced antitumor properties and improved pharmacokinetics when administered orally. It demonstrates a notable suppression of tumor expansion in mouse models of non-small cell lung cancer harboring various EGFR mutations. Furthermore, Neptinib effectively inhibits the EGFR kinase family, exhibiting IC 50 values of 0.24 nM for EGFR wt, 7.25 nM for EGFR L858R/T790M, 0.46 nM for EGFR L858R, and 1.79 nM for EGFR T790M.
Notice:
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Brand:
Targetmol
Long term storage:
Notes:
Chemical properties
Molecular weight:
443.9
Formula:
C22H23ClFN5O2
Color/Form:
Liquid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:
Technical inquiry about: TM-T89923 Neptinib
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