Topovale
CAS: 500214-53-9
Ref. TM-T9088
1mg | 95.00 € | ||
5mg | 172.00 € | ||
10mg | 237.00 € | ||
25mg | 427.00 € | ||
50mg | 630.00 € | ||
100mg | 894.00 € |
Product Information
- ARC111, ARC 111, ARC-111, Topoval
Topovale (ARC111) is a potent inhibitor of topoisomerase I. Topovale inhibits hypoxia-mediated accumulation of hypoxia-inducible factor-1alpha. Topovale exhibited low nM cytotoxicity against a panel of cancer cells. Topovale cytotoxicity as well as Topovale-induced apoptosis was reduced >100-fold in CPT-resistant topoisomerase I (TOP1)-deficient P388/CPT45 cells as compared with P388 cells.
Chemical properties
Technical inquiry about: TM-T9088 Topovale
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