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Topovale
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Topovale

CAS: 500214-53-9

Ref. TM-T9088

1mg
95.00 €
5mg
172.00 €
10mg
237.00 €
25mg
427.00 €
50mg
630.00 €
100mg
894.00 €
Estimated delivery in United States, on Wednesday 17 Apr 2024

Product Information

Name:
Topovale
Synonyms:
  • ARC111, ARC 111, ARC-111, Topoval
Description:

Topovale (ARC111) is a potent inhibitor of topoisomerase I. Topovale inhibits hypoxia-mediated accumulation of hypoxia-inducible factor-1alpha. Topovale exhibited low nM cytotoxicity against a panel of cancer cells. Topovale cytotoxicity as well as Topovale-induced apoptosis was reduced >100-fold in CPT-resistant topoisomerase I (TOP1)-deficient P388/CPT45 cells as compared with P388 cells.

Brand:
Targetmol
Long term storage:
Notes:

Chemical properties

Molecular weight:
421.45
Formula:
C23H23N3O5
Purity:
99.94%
Color/Form:
Solid
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: TM-T9088 Topovale

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