Product Information
Name:Avelestat
Controlled Product
Synonyms:
- 6-methyl-5-(2-methylpyrazol-3-yl)-N-[(5-methylsulfonylpyridin-2-yl)methyl]-2-oxo-1-[3-(trifluoromethyl)phenyl]pyridine-3-carboxamide
Brand:TRC
Description:Applications Avelstat inhibits plasma neutrophil elastase (NE) activity in zymosan-stimulated whole blood, and also inhibits NE activity on the surface of stimulated polymorphonuclear cells and in the supernatant of primed, stimulated cells.References Stevens, T., et al.: J. Pharmacol. Exp. Ther., 339, 313 (2011)
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:545.53
Formula:C25H22F3N5O4S
Color/Form:Neat
InChI:InChI=1S/C25H22F3N5O4S/c1-15-20(22-9-10-31-32(22)2)12-21(23(34)30-13-17-7-8-19(14-29-17)38(3,36)37)24(35)33(15)18-6-4-5-16(11-18)25(26,27)28/h4-12,14H,13H2,1-3H3,(H,30,34)
InChI key:InChIKey=HOOWCUZPEFNHDT-ZETCQYMHSA-N
SMILES:N[C@H](C(=O)O)c1cc(O)cc(O)c1
Technical inquiry about: Avelestat
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