5-Fluoro Uracil

CAS: 51-21-8

Ref. TR-F596000

Product Information

• Name: 5-Fluoro Uracil
• Synonyms: Fluorouracil, 5-Fluoropyrimidine-2,4(1H,3H)-dione, Flucytosine Imp. A (EP), 2,4(1H,3H)-Pyrimidinedione, 5-fluoro-, Uracil, 5-fluoro- (8CI), 5-Fluoro-2,4(1H,3H)-pyrimidinedione, 2,4-Dihydroxy-5-fluoropyrimidine, 2,4-Dioxo-5-fluoropyrimidine, 5-FU, 5-Fluoracyl, 5-Fluoro-1H-pyrimidine-2,4-dione, 5-Fluoro-2,4-dihydroxypyrimidine, 5-Fluoro-2,4-pyrimidinedione, 5-Fluoropyrimidine-2,4-diol, 5-Fluorouracil, 5-Oncouracil, Adrucil, Arumel, Carac, Carzonal, DBL, Efudex, Efudix, Efurix, FU, Fluoroblastin, Fluoroplex, Fluorouracile Accord, Flurablastin, Fluracedyl, Fluracil, Fluracilum, Fluri, Fluril, Ftoruracil, Kecimeton, NSC 19893, Phthoruracil, Phtoruracil, Queroplex, Ro 2-9757, Sigma 03738, Timazin, U 8953, Ulup
• Brand: TRC

Description

Impurity Flucytosine EP Impurity A
Applications 5-Fluoro Uracil is is an DNA/RNA synthesis inhibitor. It is used as a potent antitumor agent since it interrupts nucleotide synthetic by inhibiting thymidylate synthase.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Longley, D., et al.: Nat. Rev. Cancer, 3, 330 (2003); Bollag, W., et al.: Eur. J. Cancer, 16, 427 (1980); Pinedo, H., et al.: J. Clin. Oncol., 6, 1653 (1988); Ishikawa, T., et al.: Biochem. Pharmacol., 55, 1091 (1998); Schuller, J., et al.: Cancer Chemother. Pharmacol., 45, 291 (2000);

Chemical properties

• Molecular weight: 130.08
• Formula: C₄H₃FN₂O₂
• Color/Form: Neat
• InChI: InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9)
• InChI key: InChIKey=GHASVSINZRGABV-UHFFFAOYSA-N
• SMILES: O=c1[nH]cc(F)c(=O)[nH]1