Product Information
Name:Rilpivirine
Controlled Product
Synonyms:
- 4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile
- Edurant
- R 278474
- TMC 278
Brand:TRC
Description:
Applications A novel non-nucleoside reverse transcriptase inhibitor. Rilpivirine seems to be well tolerated with less CNS disturbance than Efavirenz, and has non-teratogenic potential. An anti-HIV agent.
References Sun, et al.: J. Med. Chem., 41, 4648 (1998), Kashiwada, et al.: Bioorg. Med. Chem. Lett., 11, 183 (2001),
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:366.42
Formula:C22H18N6
Color/Form:Neat
InChI:InChI=1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+
SMILES:Cc1cc(/C=C/C#N)cc(C)c1N=c1ccnc(Nc2ccc(C#N)cc2)[nH]1
Technical inquiry about: Rilpivirine
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