Sildenafil-d8

CAS: 951385-68-5

Ref. TR-S435003

Product Information

• Name: Sildenafil-d8
• Synonyms: 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 5-[2-ethoxy-5-[(4-methyl-1-piperazinyl-2,2,3,3,5,5,6,6-d8), BDD 10402sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-
• Brand: TRC

Description

Applications Sildenafil-d8 is the labeled analogue of Sildenafil (S435000), an orally active selective type 5 cGMP phosphodiesterase inhibitor.
References Terrett, N.K., et al.: Bioorg. Med. Chem. Lett., 6, 1819 (1996); Goldstein, I., et al.: N. Engl. J. Med., 338, 1397 (1998)

Chemical properties

• Molecular weight: 482.63
• Formula: C₂₂₂H₈H₂₂N₆O₄S
• Color/Form: Neat
• InChI: InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)/i10D2,11D2,12D2,13D2
• InChI key: InChIKey=BNRNXUUZRGQAQC-BGKXKQMNSA-N
• SMILES: [2H]C1([2H])N(C)C([2H])([2H])C([2H])([2H])N(S(=O)(=O)c2ccc(OCC)c(-c3nc4c(CCC)nn(C)c4c(=O)[nH]3)c2)C1([2H])[2H]