CymitQuimica logo
Angiogénese

Angiogénese

Os inibidores da angiogênese são compostos que interferem na formação de novos vasos sanguíneos, um processo crítico no crescimento e metástase do câncer. Ao inibir a angiogênese, esses compostos podem restringir o suprimento de sangue para os tumores, retardando ou interrompendo seu crescimento. Os inibidores da angiogênese são essenciais na pesquisa do câncer e no desenvolvimento terapêutico, fornecendo insights sobre os mecanismos de progressão tumoral e oferecendo potenciais tratamentos para o câncer e outras doenças relacionadas à angiogênese. Na CymitQuimica, oferecemos uma ampla gama de inibidores da angiogênese de alta qualidade para apoiar sua pesquisa em oncologia e biologia vascular.

Subcategorias de "Angiogénese"

Exibir 6 mais subcategorias

Foram encontrados 2061 produtos de "Angiogénese"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • Sulfatinib
    Targetmol
    + Info

    Sulfatinib

    CAS:
    <p>Sulfatinib (KDR-IN-1) (HMPL-012) is a potent and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC 50 s ranging from 1 to</p>
    Fórmula:C24H28N6O3S
    Pureza:99.21% - >99.99%
    Cor e Forma:Solid
    Peso molecular:480.58

    Ref: TM-T4075

  • Henatinib
    Targetmol
    + Info

    Henatinib

    CAS:
    Henatinib: orally active multi-kinase inhibitor targeting VEGFR-2, c-kit, PDGFR with antitumor effects.
    Fórmula:C25H29FN4O4
    Cor e Forma:Solid
    Peso molecular:468.52

    Ref: TM-T63011

  • Risvodetinib
    Targetmol
    + Info

    Risvodetinib

    CAS:
    Risvodetinib: potent inhibitor of protein tyrosine kinases c-Abl1, c-Abl2, and c-kit.
    Fórmula:C33H34N8O2
    Cor e Forma:Solid
    Peso molecular:574.68

    Ref: TM-T69979

  • EGFR-IN-33
    Targetmol
    + Info

    EGFR-IN-33

    CAS:
    EGFR-IN-33, a low-toxicity acrylamide, inhibits EGFR, aiding against cancer, especially NSCLC (from WO2021185348A1, comp. 13).
    Fórmula:C26H25ClN6O2
    Cor e Forma:Solid
    Peso molecular:488.97

    Ref: TM-T63264

  • EGFR kinase inhibitor 1
    Targetmol
    + Info

    EGFR kinase inhibitor 1

    CAS:
    Potent EGFR blocker; acts on WT, L858R/T790M (IC50: 1.7 nM), less on T790M/C797S; stalls cell cycle, induces apoptosis, deters metastasis.
    Fórmula:C30H31N7O2
    Cor e Forma:Solid
    Peso molecular:521.61

    Ref: TM-T63648

  • FGFR-IN-2
    Targetmol
    + Info

    FGFR-IN-2

    CAS:
    FGFR-IN-2 (compound 1) is a potent inhibitor of FGFR, acting on FGFR1 (IC50: 7.3 nM), FGFR2 (IC50: 4.3 nM), FGFR3 (IC50: 7.6 nM) and FGFR4 (IC50: 11 nM).
    Fórmula:C25H30N6O2
    Cor e Forma:Solid
    Peso molecular:446.54

    Ref: TM-T62653

  • EGFR-IN-30
    Targetmol
    + Info

    EGFR-IN-30

    CAS:
    EGFR-IN-30 is an EGFR inhibitor (IC50: 1-10 nM, <1 nM WT/mutants) with potential in cancer research.
    Fórmula:C28H33BrN7O2P
    Cor e Forma:Solid
    Peso molecular:610.49

    Ref: TM-T73108

  • FLT3/ITD-IN-4
    Targetmol
    + Info

    FLT3/ITD-IN-4

    CAS:
    FLT3/ITD-IN-4 inhibits FLT3-ITD mutations in acute myeloid leukemia (IC50: 2.3 nM).
    Fórmula:C25H22N4O5
    Cor e Forma:Solid
    Peso molecular:458.47

    Ref: TM-T62863

  • EGFR mutant-IN-1
    Targetmol
    + Info

    EGFR mutant-IN-1

    EGFR mutant-in-1, a 5-methylpyrimidopyridone, selectively inhibits EGFRL858R/T790M/C797S mutants with an IC50 of 27.5 nM, lessening EGFRWT impact.
    Fórmula:C34H39ClFN7O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:632.17

    Ref: TM-T11164

  • OTS447
    Targetmol
    + Info

    OTS447

    CAS:
    OTS447 is a potent FLT3 inhibitor (IC50: 21 nM) with potential anticancer activity for cancer research .
    Fórmula:C27H32ClN3O2
    Pureza:98.78%
    Cor e Forma:Solid
    Peso molecular:466.02

    Ref: TM-T62979

  • GW-6604
    Targetmol
    + Info

    GW-6604

    CAS:
    GW-6604 is an ALK5 inhibitor and shows clear antifibrotic effects resulting in liver function improvement.
    Fórmula:C19H14N4
    Pureza:99.6%
    Cor e Forma:Solid
    Peso molecular:298.34

    Ref: TM-T9947

  • CT-721
    Targetmol
    + Info

    CT-721

    CAS:
    CT-721: potent, time-bound Bcr-Abl inhibitor, IC50 21.3 nM, effective against CML.
    Fórmula:C30H29ClN6O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:525.04

    Ref: TM-T10897

  • Cinsebrutinib
    Targetmol
    + Info

    Cinsebrutinib

    CAS:
    Cinsebrutinib, a Bruton's tyrosine kinase inhibitor, holds potential for research in cancer treatment.
    Fórmula:C22H26FN3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:383.46

    Ref: TM-T79841

  • EGFR-IN-74
    Targetmol
    + Info

    EGFR-IN-74

    EGFR-IN-74 is a potent inhibitor targeting EGFR, specifically effective against the L858R/T790M mutations, exhibiting an IC50 value of 138 nM.
    Fórmula:C32H28BrF3N6O4S
    Cor e Forma:Solid
    Peso molecular:729.57

    Ref: TM-T73170

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    PI3K/VEGFR2-IN-1

    CAS:
    PI3K/VEGFR2-IN-1 is a potent dual inhibitor targeting both PI3K and VEGFR2 with IC50 values of 2.21 μM for PI3K and 68 μM for VEGFR2, respectively.
    Fórmula:C17H14ClN3OS
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:343.83

    Ref: TM-T72713

  • Atiprimod (free base)
    Targetmol
    + Info

    Atiprimod (free base)

    CAS:
    Atiprimod: an oral azaspirane inhibiting STAT3, blocking IL-6/VEGF pathways, and promoting apoptosis by downregulating Bcl-2 and Mcl-1.
    Fórmula:C22H44N2
    Cor e Forma:Solid
    Peso molecular:336.6

    Ref: TM-T71176

  • Upadacitinib tartrate
    Targetmol
    + Info

    Upadacitinib tartrate

    CAS:
    Upadacitinib: potent, selective JAK1 inhibitor, 74x preferential to JAK2, effective in rat arthritis.
    Fórmula:C21H33F3N6O11
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:602.521

    Ref: TM-T7503L

  • 2′-Thioadenosine
    Targetmol
    + Info

    2′-Thioadenosine

    CAS:
    2'-Thioadenosine (PD157432) serves as a selective and irreversible inhibitor of ErbB-1 and ErbB-2 tyrosine kinases, demonstrating an IC50 value of 45 µM against
    Fórmula:C10H13N5O3S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:283.31

    Ref: TM-T78634

  • YS-363
    Targetmol
    + Info

    YS-363

    CAS:
    <p>YS-363 is a potent, selective, and orally active inhibitor of the epidermal growth factor receptor (EGFR), exhibiting half-maximal inhibitory concentrations (</p>
    Fórmula:C30H30N4O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:494.58

    Ref: TM-T80748

  • Pivanex
    Targetmol
    + Info

    Pivanex

    CAS:
    Pivanex, an oral HDAC inhibitor, targets metastasis, angiogenesis, reduces Bcr-Abl protein, and promotes apoptosis.
    Fórmula:C10H18O4
    Pureza:≥98%
    Cor e Forma:Solid
    Peso molecular:202.25

    Ref: TM-T16545