CymitQuimica logo
Angiogénese

Angiogénese

Os inibidores da angiogênese são compostos que interferem na formação de novos vasos sanguíneos, um processo crítico no crescimento e metástase do câncer. Ao inibir a angiogênese, esses compostos podem restringir o suprimento de sangue para os tumores, retardando ou interrompendo seu crescimento. Os inibidores da angiogênese são essenciais na pesquisa do câncer e no desenvolvimento terapêutico, fornecendo insights sobre os mecanismos de progressão tumoral e oferecendo potenciais tratamentos para o câncer e outras doenças relacionadas à angiogênese. Na CymitQuimica, oferecemos uma ampla gama de inibidores da angiogênese de alta qualidade para apoiar sua pesquisa em oncologia e biologia vascular.

Subcategorias de "Angiogénese"

Exibir 6 mais subcategorias

Foram encontrados 2002 produtos de "Angiogénese"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • HDHD4-IN-1
    Targetmol
    + Info

    HDHD4-IN-1

    CAS:
    HDHD4-IN-1 (compound 3) is an inhibitor of N-acetylneuraminate-9-phosphate phosphatase (HDHD4) with an IC50 value of 11 μM. It is utilized in the research of neurological disorders.
    Fórmula:C12H22NO11P
    Cor e Forma:Solid
    Peso molecular:387.28

    Ref: TM-T201744

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    FGFR4-IN-9

    FGFR4-IN-9 is a selective inhibitor of FGFR4 (IC50: 75.3 nM) that effectively inhibits the growth and angiogenesis of hepatocellular carcinoma cells.
    Fórmula:C24H22ClF3N4O4
    Cor e Forma:Solid
    Peso molecular:522.9

    Ref: TM-T63662

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    VEGFR-2/DHFR-IN-2

    VEGFR-2/DHFR-IN-2 inhibits VEGFR-2 & DHFR (IC50: 0.623 & 9.085 μM), toxic to C26, HepG2, MCF7 cells (IC50: 3.59-8.38 μM), promising for cancer study.
    Fórmula:C21H21NO4
    Cor e Forma:Solid
    Peso molecular:351.4

    Ref: TM-T61229

  • BMS-066
    Targetmol
    + Info

    BMS-066

    CAS:
    BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.
    Fórmula:C19H21N7O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:379.42

    Ref: TM-T14669

  • JAK3/BTK-IN-7
    Targetmol
    + Info

    JAK3/BTK-IN-7

    CAS:
    JAK3/BTK-IN-7 (XL-12), characterized as a JAK3/BTK inhibitor, exhibits IC 50 values of 2 nM and 14 nM for JAK3 and BTK respectively. This compound demonstrates anti-inflammatory properties and is applicable in research related to rheumatoid arthritis [1].
    Fórmula:C29H30N8O4
    Cor e Forma:Solid
    Peso molecular:554.6

    Ref: TM-T86758

  • TYK2 ligand 2
    Targetmol
    + Info

    TYK2 ligand 2

    CAS:
    <p>TYK2ligand 2 is the TYK2 ligand of PROTACTYD-68. TYD-68 is a highly potent and selective CRBN-recruiting TYK2 PROTAC degrader with a DC50 value of 0.42 nM.</p>
    Fórmula:C24H20FN7O4
    Cor e Forma:Solid
    Peso molecular:489.458

    Ref: TM-T206678

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    VEGFR-2-IN-17

    VEGFR-2-IN-17 (15a) is a potent VEGFR-2 inhibitor with an IC50 of 67.25 nM, showing significant antitumor effects.
    Fórmula:C21H14ClN3O2
    Cor e Forma:Solid
    Peso molecular:375.81

    Ref: TM-T61542

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    FGFR4-IN-10

    FGFR4-IN-10 (compound 5a) is a potent, selective FGFR4 inhibitor with IC50 of 70.7 nM, sparing FGFR1-3.
    Fórmula:C20H19F3N6O3
    Cor e Forma:Solid
    Peso molecular:448.4

    Ref: TM-T62682

  • Brefeldin A 4-O-nicotinate
    Targetmol
    + Info

    Brefeldin A 4-O-nicotinate

    CAS:
    Brefeldin A 4-O-nicotinate (CHNQD-01228) is a dual inhibitor of Arf1 and BMX proteins with an IC50 value of 0.22 μM for T24 cell proliferation. It also suppresses T24 cell migration and colony formation in a dose-dependent manner, induces G1 phase arrest, and triggers apoptosis. By targeting BMX proteins, it inhibits the AKT/p-AKT and STAT3/p-STAT3 signaling pathways, while also inhibiting Arf1 proteins to eliminate bladder cancer stem cells and activate antitumor immunity, thus exhibiting anticancer activity. Brefeldin A 4-O-nicotinate is applicable in research related to bladder cancer.
    Fórmula:C22H27NO5
    Cor e Forma:Solid
    Peso molecular:385.453

    Ref: TM-T206652

  • ALK ligand-Linker Conjugate 1
    Targetmol
    + Info

    ALK ligand-Linker Conjugate 1

    CAS:
    ALK ligand-Linker Conjugate 1 is an ALK ligand-connector conjugate used for the synthesis of PROTACALK degrader-4.
    Fórmula:C36H45N5O3
    Cor e Forma:Solid
    Peso molecular:595.77

    Ref: TM-T212133

  • EGFR/VEGFR2-IN-3
    Targetmol
    + Info

    EGFR/VEGFR2-IN-3

    CAS:
    EGFR/VEGFR2-IN-3 (compound 9) is an effective inhibitor of EGFR and VEGFR-2, demonstrating IC50 values of 0.129 µM for EGFR, 0.142 µM for VEGFR-2, and 3.428 µM for COX-2. This compound exhibits cytotoxic properties and induces cell apoptosis (apoptosis) as well as cell cycle arrest at the G2/M phase.
    Fórmula:C24H20ClN5O2S2
    Cor e Forma:Solid
    Peso molecular:510.03

    Ref: TM-T201562

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    FAK-IN-4

    FAK-IN-4 (Compound 7d) has anticancer activities that can induce cell apoptosis. FAK-IN-4 is potential inhibitor of FAK [1].
    Fórmula:C20H22N4O
    Cor e Forma:Solid
    Peso molecular:334.41

    Ref: TM-T61019

  • Tandutinib sulfate
    Targetmol
    + Info

    Tandutinib sulfate

    CAS:
    Tandutinib (MLN518) sulfate is an effective and selective inhibitor of FLT3, with an IC50 value of 0.22 μM. It also inhibits c-Kit and PDGFR, displaying IC50 values of 0.17 μM and 0.20 μM respectively. This compound can be utilized in the treatment of acute myeloid leukemia and has the capability to cross the blood-brain barrier.
    Fórmula:C31H44N6O8S
    Cor e Forma:Solid
    Peso molecular:660.78

    Ref: TM-T201851

  • D-69491 hydrochloride
    Targetmol
    + Info

    D-69491 hydrochloride

    CAS:
    D-69491 hydrochloride is an inhibitor of HER-2 tyrosine kinase activity, blocking the phosphorylation of HER-2 and inhibiting the proliferation of SKOV-3 cells. It exhibits antitumor activity.
    Fórmula:C25H26Cl2FN7O3
    Cor e Forma:Solid
    Peso molecular:562.42

    Ref: TM-T201568

  • Hypothemycin
    Targetmol
    + Info

    Hypothemycin

    CAS:
    Hypothemycin, a fungal polyketide, inhibits multiple kinases (VEGFR, MEK, FLT-3, PDGFR, ERK) with Kis ranging from 10 nM to 2.4 μM.
    Fórmula:C19H22O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:378.37

    Ref: TM-T15542

  • CEE321
    Targetmol
    + Info

    CEE321

    CAS:
    CEE321 is an effective pan-JAK inhibitor with an IC50 of 54 nM. It effectively inhibits biomarkers associated with atopic dermatitis.
    Fórmula:C18H16ClN5O
    Cor e Forma:Solid
    Peso molecular:353.806

    Ref: TM-T204824

  • 7PPD-Q
    Targetmol
    + Info

    7PPD-Q

    CAS:
    7PPD-Q is a substituted p-phenylenediamine antioxidant derivative. It exhibits toxicity towards the bacterium V. fischeri (EC50= 14.9 mg/L).
    Fórmula:C19H24N2O2
    Cor e Forma:Solid
    Peso molecular:312.41

    Ref: TM-T201775

  • FGFR-IN-15
    Targetmol
    + Info

    FGFR-IN-15

    FGFR-IN-15 (compound 18i) acts as a pan-FGFR inhibitor, exhibiting potent inhibitory activity against FGFR1-4.
    Fórmula:C22H23N5O5S
    Cor e Forma:Solid
    Peso molecular:469.51

    Ref: TM-T201821

  • Pred17
    Targetmol
    + Info

    Pred17

    Pred17 is an effective EGFR inhibitor with potential applications in lung cancer research.
    Fórmula:C27H22BN3O
    Cor e Forma:Solid
    Peso molecular:415.29

    Ref: TM-T201786

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    BTK-IN-8

    BTK-IN-8: potent, selective covalent BTK inhibitor; IC50=0.22 nM, Kd=0.91 nM; effective in blood CD69 cells (IC50=0.029 μM).
    Fórmula:C26H36N6O3
    Cor e Forma:Solid
    Peso molecular:480.6

    Ref: TM-T63173