Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Epoxomicin
CAS:<p>Epoxomicin, a selective proteasome inhibitor, chiefly blocks CH-L activity, mildly affecting T-L and PGPH at lower rates.</p>Fórmula:C28H50N4O7Pureza:98.65% - 98.86%Cor e Forma:White To Off-White SolidPeso molecular:554.72Eprenetapopt
CAS:<p>Eprenetapopt (PRIMA-1Met) restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells.</p>Fórmula:C10H17NO3Pureza:98.75% - 99.57%Cor e Forma:SolidPeso molecular:199.25Helichrysetin
CAS:<p>Helichrysetin shows mild anti-HIV-1 activity and potential as an anticancer agent with cytotoxic effects on A549, MCF-7, Ca Ski, HT-29 cells.</p>Fórmula:C16H14O5Pureza:96.32% - ≥95%Cor e Forma:SolidPeso molecular:286.28Flavokawain B
CAS:<p>Flavokawain B inhibits NO and PGE2, causes oxidative stress, and induces apoptosis, with potential for treating prostate cancer.</p>Fórmula:C17H16O4Pureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:284.31Ligustrazine
CAS:<p>Ligustrazine (Tetramethylpyrazine), a natural compound isolated from Chuan Xiong shows anti-inflammation, antioxidant, antiplatelet, and antiapoptosis effects.</p>Fórmula:C8H12N2Pureza:99.91% - >99.99%Cor e Forma:White Crystals Or PowderPeso molecular:136.19Capmatinib 2HCl.H2O
CAS:<p>Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity.</p>Fórmula:C23H21Cl2FN6O2Pureza:99.77%Cor e Forma:SolidPeso molecular:503.36Tandutinib
CAS:<p>Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3</p>Fórmula:C31H42N6O4Pureza:99.45% - ≥98%Cor e Forma:White SolidPeso molecular:562.7Quinidine sulfate dihydrate
CAS:<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Fórmula:C40H54N4O10SPureza:99.85%Cor e Forma:White To Light Yellow Crystal PowdePeso molecular:782.9LDN-57444
CAS:<p>LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) .</p>Fórmula:C17H11Cl3N2O3Pureza:97.8% - 99.87%Cor e Forma:SolidPeso molecular:397.64Navtemadlin
CAS:<p>Navtemadlin (AMG232) is a potent, selective and orally available inhibitor of p53-MDM2 interaction (IC50: 0.6 nM).Cost-effective and quality-assured.</p>Fórmula:C28H35Cl2NO5SPureza:95.55% - 99.08%Cor e Forma:SolidPeso molecular:568.55Paederosidic acid
CAS:<p>Paederosidic acid shows anti-tumor, anticonvulsant, and sedative properties, may treat epilepsy by modulating brain GABA and glutamate levels.</p>Fórmula:C18H24O12SPureza:98% - 99.56%Cor e Forma:SolidPeso molecular:464.445'-Methylthioadenosine
CAS:<p>5'-Methylthioadenosine (Methylthioadenosine) is produced from S-adenosylmethionine and behaves as a powful inhibitory product.</p>Fórmula:C11H15N5O3SPureza:99.32% - 99.34%Cor e Forma:SolidPeso molecular:297.33DMU-212
CAS:<p>DMU-212, a Resveratrol derivative, has antimitotic, antiproliferative, antioxidant properties; induces apoptosis via ERK1/2.</p>Fórmula:C18H20O4Pureza:99.86%Cor e Forma:SolidPeso molecular:300.35(20S)-Protopanaxatriol
CAS:<p>(20S)-Protopanaxatriol (g-PPT)(g-PPT), a metabolite of ginsenoside, could regulate endothelial cell functions through the estrogen receptor and glucocorticoid</p>Fórmula:C30H52O4Pureza:95% - 99%Cor e Forma:SolidPeso molecular:476.73(Rac)-Idroxioleic acid
CAS:<p>(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a fatty acid amide hydrolase inhibitor with anti-tumor effect.</p>Fórmula:C18H34O3Pureza:≥98%Cor e Forma:SolidPeso molecular:298.46OsMundacetone
CAS:<p>OsMundacetone (4-(3,4-Dihydroxyphenyl)-3-buten-2-one) is a natual product isolated from Rhizoma osmundae.</p>Fórmula:C10H10O3Pureza:99.59% - ≥95%Cor e Forma:SolidPeso molecular:178.18K-Ras(G12C) inhibitor 12
CAS:<p>K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of oncogenic K-Ras(G12C).</p>Fórmula:C15H17ClIN3O3Pureza:97.16%Cor e Forma:SolidPeso molecular:449.67DL-Buthionine-(S,R)-sulfoximine
CAS:<p>DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.</p>Fórmula:C8H18N2O3SPureza:98% - 99.64%Cor e Forma:White Fine PowderPeso molecular:222.31LY-411575
CAS:<p>LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage.</p>Fórmula:C26H23F2N3O4Pureza:97.03% - 99.38%Cor e Forma:SolidPeso molecular:479.48NVP-TAE 226
CAS:<p>NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.</p>Fórmula:C23H25ClN6O3Pureza:98.07% - 98.78%Cor e Forma:SolidPeso molecular:468.94Orantinib
CAS:<p>Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.</p>Fórmula:C18H18N2O3Pureza:98.92% - 99.52%Cor e Forma:SolidPeso molecular:310.35Mycophenolate Mofetil
CAS:<p>Mycophenolate Mofetil (TM-MMF), is an immunosuppressive agent, 2-morpholinoethyl ester of MPA, and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).</p>Fórmula:C23H31NO7Pureza:98.27% - 99.85%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:433.49Carfilzomib
CAS:<p>Carfilzomib (PR-171) is a proteasome inhibitor that irreversibly binds to the chymotrypsin of the 20S proteasome.</p>Fórmula:C40H57N5O7Pureza:99.6% - 99.84%Cor e Forma:SolidPeso molecular:719.91Sclareol
CAS:<p>Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.</p>Fórmula:C20H36O2Pureza:99.58% - 99.97%Cor e Forma:White Fine PowderPeso molecular:308.5TW-37
CAS:<p>TW-37 is an nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 (Ki: 0.29/1.11/0.26 μM).</p>Fórmula:C33H35NO6SPureza:97.06% - ≥95%Cor e Forma:SolidPeso molecular:573.7PUMA BH3 Free base
<p>PUMA BH3 acetate (PUMA BH3 Free base) is a p53 positive regulator of apoptosis (PUMA) BH3 domain polypeptide that acts as a direct activator of Bak with a Kd of</p>Fórmula:C130H206N42O45SPureza:96.64%Cor e Forma:SolidPeso molecular:3109.35Eltrombopag
CAS:<p>Eltrombopag (SB-497115-GR), an orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity, binds to and stimulates the platelet</p>Fórmula:C25H22N4O4Pureza:99.27%Cor e Forma:Orange To Red SolidPeso molecular:442.47Ginkgetin
CAS:<p>Ginkgetin: antiviral, antifungal, anti-inflammatory; COX-2 reducer; STAT3 inhibitor; pro-apoptotic in cancer; neuroprotective in Parkinson's.</p>Fórmula:C32H22O10Pureza:98.63% - 99.94%Cor e Forma:SolidPeso molecular:566.51Valproic Acid
CAS:<p>Valproic Acid (2-Propylpentanoic Acid) is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels.</p>Fórmula:C8H16O2Pureza:97.78% - 99%Cor e Forma:Colourless To Pale Yellow Liquid ViscousPeso molecular:144.21Brassinolide
CAS:<p>Brassinolide (Brassin lactone) is a plant hormone isolated from rapeseed (Brassica napus) promoting stem elongation and cell division.</p>Fórmula:C28H48O6Pureza:98% - 99.189%Cor e Forma:Off-White SolidPeso molecular:480.68PRLX-93936
CAS:<p>PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.</p>Fórmula:C21H24N4O2Cor e Forma:SolidPeso molecular:364.44PNU-74654
CAS:<p>PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).</p>Fórmula:C19H16N2O3Pureza:97.27%Cor e Forma:SolidPeso molecular:320.34TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Cor e Forma:SolidPeso molecular:588.07Luminespib
CAS:<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C26H31N3O5Pureza:98% - 99.25%Cor e Forma:SolidPeso molecular:465.54SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Fórmula:C20H14FN3OPureza:98% - 99.84%Cor e Forma:Pale YellowPeso molecular:331.34DD1
CAS:<p>DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.</p>Fórmula:C16H14N2O3Pureza:99.57%Cor e Forma:SolidPeso molecular:282.29Rosmarinic acid
CAS:<p>Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities.</p>Fórmula:C18H16O8Pureza:98.88% - 99.73%Cor e Forma:Brown Fine PowderPeso molecular:360.31NSC59984
CAS:<p>NSC59984, a p53 pathway activator, induces mutant p53 protein degradation and p73 activation.</p>Fórmula:C12H15N3O4Pureza:99.33% - 99.59%Cor e Forma:SolidPeso molecular:265.2720(R)-Ginsenoside Rh2
CAS:<p>20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.</p>Fórmula:C36H62O8Pureza:99.58%Cor e Forma:SolidPeso molecular:622.87SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Fórmula:C22H28N2O2Pureza:98.58%Cor e Forma:SolidPeso molecular:352.47Millepachine
CAS:<p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>Fórmula:C22H22O4Pureza:99.73%Cor e Forma:SolidPeso molecular:350.41Vanillyl Alcohol
CAS:<p>Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant and anti-nociceptive activities.</p>Fórmula:C8H10O3Pureza:97.02% - 98.42%Cor e Forma:Crystalline White To Off-White PowderPeso molecular:154.16Tubeimoside I
CAS:<p>Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).</p>Fórmula:C63H98O29Pureza:98.89% - 99.94%Cor e Forma:SolidPeso molecular:1319.43Pyrogallol
CAS:<p>Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.</p>Fórmula:C6H6O3Pureza:99.88%Cor e Forma:SoildPeso molecular:126.11Ixabepilone
CAS:<p>Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor.</p>Fórmula:C27H42N2O5SPureza:98% - 99.50%Cor e Forma:SolidPeso molecular:506.7NVP 231
CAS:<p>NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.</p>Fórmula:C25H25N3O2SPureza:99.16% - ≥95%Cor e Forma:SolidPeso molecular:431.55Taurolidine
CAS:<p>Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.</p>Fórmula:C7H16N4O4S2Pureza:99.79% - 99.81%Cor e Forma:SolidPeso molecular:284.36DC260126
CAS:<p>DC260126 is a small-molecule antagonist of FFA1 (GPR40)</p>Fórmula:C16H18FNO2SPureza:99.77%Cor e Forma:SolidPeso molecular:307.38Y-27632 dihydrochloride
CAS:<p>View and buy Y-27632 dihydrochloride from TargetMol.Y-27632 is a selective inhibitor of ROCKs.Cited in 10 publications.</p>Fórmula:C14H21N3O·2HClPureza:97.96% - 99.98%Cor e Forma:SolidPeso molecular:320.26Rimiducid
CAS:<p>Rimiducid, a tacrolimus analogue, dimerizes FKBP domains to activate Caspase 9 and induce apoptosis; binds FKBP12 weakly.</p>Fórmula:C78H98N4O20Pureza:99.54%Cor e Forma:SolidPeso molecular:1411.63Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Fórmula:C23H22ClNO2Pureza:99.25%Cor e Forma:Yellowish SolidPeso molecular:379.88CCCP
CAS:<p>CCCP blocks STING activation, TBK1, IRF3 signaling, and IFN-β production by disrupting MMP.</p>Fórmula:C9H5ClN4Pureza:97.15% - 99.64%Cor e Forma:Yellow To Orange PowderPeso molecular:204.62NSC 15364
CAS:<p>NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.</p>Fórmula:C13H14N4OPureza:98.67%Cor e Forma:SolidPeso molecular:242.28Eriocitrin
CAS:<p>Eriocitrin: an antioxidative flavonoid; reduces exercise-induced oxidative damage and lipids; fights fatty liver and inhibits carbonic anhydrase VA.</p>Fórmula:C27H32O15Pureza:98.41% - 99.11%Cor e Forma:SolidPeso molecular:596.53Trabectedin
CAS:<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Fórmula:C39H43N3O11SPureza:≥98%Cor e Forma:SolidPeso molecular:761.84Mirodenafil dihydrochloride
CAS:<p>Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.</p>Fórmula:C26H39Cl2N5O5SPureza:99.64% - 99.78%Cor e Forma:SolidPeso molecular:604.59Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Fórmula:C28H26N4O3Pureza:99.24% - 99.82%Cor e Forma:Off-White PowderPeso molecular:466.53Deoxypodophyllotoxin
CAS:<p>Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.</p>Fórmula:C22H22O7Pureza:99.65% - 99.84%Cor e Forma:SolidPeso molecular:398.41Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Fórmula:C19H23NO4Pureza:99.02% - 99.73%Cor e Forma:White PowderPeso molecular:329.39Tacedinaline
CAS:<p>Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity.</p>Fórmula:C15H15N3O2Pureza:96.83% - 99.15%Cor e Forma:WhitePeso molecular:269.33-O-Methylgallic acid
CAS:<p>3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and</p>Fórmula:C8H8O5Pureza:99.56%Cor e Forma:SolidPeso molecular:184.15W-7 hydrochloride
CAS:<p>W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride</p>Fórmula:C16H22Cl2N2O2SPureza:99.63%Cor e Forma:White Crystalline SolidPeso molecular:377.32ISOGINKGETIN
CAS:<p>ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.</p>Fórmula:C32H22O10Pureza:98% - 99.72%Cor e Forma:SolidPeso molecular:566.51Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Cor e Forma:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Clobenpropit dihydrobromide
CAS:<p>Clobenpropit dihydrobromide is a potent antagonist and inverse agonist of histamine H3R (histamine H3LR,pEC50 of 8.07)</p>Fórmula:C14H19Br2ClN4SPureza:99.86%Cor e Forma:SolidPeso molecular:470.7Cysteamine hydrochloride
CAS:<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Fórmula:C2H7NS·HClPureza:99.34% - 99.87%Cor e Forma:White Crystalline Powder With A Strong And Disagreeable SmellPeso molecular:113.61SCR130
CAS:<p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>Fórmula:C19H13Cl2N3O2SPureza:98.9%Cor e Forma:SolidPeso molecular:418.3Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Cor e Forma:SolidPeso molecular:384.27Otenaproxesul
CAS:<p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>Fórmula:C21H19NO3SPureza:98.76% - 99.13%Cor e Forma:SolidPeso molecular:365.45Flavokawain A
CAS:<p>NSC-37445 shows anti-tumor properties; Flavokawain A may reduce inflammation by hindering specific signaling in macrophages.</p>Fórmula:C18H18O5Pureza:97.1% - 99.72%Cor e Forma:SolidPeso molecular:314.332iCRT3
CAS:<p>iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.</p>Fórmula:C23H26N2O2SPureza:98.32% - 98.47%Cor e Forma:SolidPeso molecular:394.53Alvespimycin hydrochloride
CAS:<p>Alvespimycin hydrochloride (BMS 826476) is a potent HSP90 inhibitor with IC50 of 62 nM. Phase 2.</p>Fórmula:C32H48N4O8·HClPureza:99.94%Cor e Forma:SolidPeso molecular:653.21Nivolumab
CAS:<p>Nivolumab is a monoclonal antibody, a humanized IgG4 antibody to PD-1. Nivolumab has antitumor activity. Cost-effective and quality-assured.</p>Pureza:98% - 98%Cor e Forma:LiquidPeso molecular:146 kDaGanoderic acid D
CAS:<p>Ganoderic acid D, a Ganoderma component, inhibits HeLa cell growth with an IC50 of 17.3µM after 48h.</p>Fórmula:C30H42O7Pureza:98.06% - 99.98%Cor e Forma:SolidPeso molecular:514.65Pembrolizumab
CAS:<p>Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.</p>Pureza:95% - 99.70%Cor e Forma:LiquidPeso molecular:149 kDaTorin 2
CAS:<p>Torin 2: mTOR inhibitor, IC50=0.25 nM, 800x more selective than PI3K, with EC50=28/35/118 nM for ATM/ATR/DNA-PK.</p>Fórmula:C24H15F3N4OPureza:98.31% - 99.32%Cor e Forma:SolidPeso molecular:432.4EGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Cor e Forma:SolidPeso molecular:413.4HJC0152 hydrochloride
CAS:<p>HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.</p>Fórmula:C15H14Cl3N3O4Pureza:99.01% - 99.06%Cor e Forma:SolidPeso molecular:406.64IITZ-01
CAS:<p>IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)</p>Fórmula:C26H23FN8OPureza:99.31%Cor e Forma:SolidPeso molecular:482.51Lupiwighteone
CAS:<p>Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.</p>Fórmula:C20H18O5Pureza:98.92%Cor e Forma:SolidPeso molecular:338.35NQDI-1
CAS:<p>NQDI-1 (NQDI 1) is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1, MAP3K5) (IC50/Ki: 3 μM/500 nM).</p>Fórmula:C19H13NO4Pureza:97.1% - 98.10%Cor e Forma:SolidPeso molecular:319.313-Nitropropanoic acid
CAS:<p>3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.</p>Fórmula:C3H5NO4Pureza:98.35% - 99.94%Cor e Forma:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecular:119.08CCG-1423
CAS:<p>CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.</p>Fórmula:C18H13ClF6N2O3Pureza:99.80%Cor e Forma:SolidPeso molecular:454.75TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Cor e Forma:SolidPeso molecular:428.82BTdCPU
CAS:<p>BTdCPU is a potent activator of heme-regulated eIF2α kinase (HRI) . BTdCPU promotes eIF2α phosphorylation and induced apoptosis in resistant cell.</p>Fórmula:C13H8Cl2N4OSPureza:98.94% - 99.59%Cor e Forma:SolidPeso molecular:339.2Solamargine
CAS:<p>Solamargine, a steroidal alkaloid from Solanum nigrum, inhibits cancer cell growth and induces apoptosis.</p>Fórmula:C45H73NO15Pureza:99.17% - 99.96%Cor e Forma:SolidPeso molecular:868.06Demethylzeylasteral
CAS:<p>Demethylzeylasteral (T-96), isolated from Tripterygium wilfordii, has anti-inflammatory, immunosuppressive and anti-tumor activities.</p>Fórmula:C29H36O6Pureza:98.74% - 99.82%Cor e Forma:SolidPeso molecular:480.59Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Fórmula:C50H71N13O12Pureza:95% - >99.99%Cor e Forma:SolidPeso molecular:1046.18PD168393
CAS:<p>PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.</p>Fórmula:C17H13BrN4OPureza:99.13% - 99.83%Cor e Forma:SolidPeso molecular:369.22Terameprocol
CAS:<p>Terameprocol (EM-1421), a synthetic NDGA derivative, shows potent anti-HIV, antiangiogenic, and anticancer properties.</p>Fórmula:C22H30O4Pureza:99.38%Cor e Forma:SolidPeso molecular:358.47Dexrazoxane
CAS:<p>Dexrazoxane (ICRF-187) is a mitosis-blocking anticancer drug, iron chelator, and anthracycline cardioprotectant.</p>Fórmula:C11H16N4O4Pureza:99.88%Cor e Forma:SolidPeso molecular:268.27Mancozeb
CAS:<p>Mancozeb is a fungicide of ethylene-bis-dithiocarbamate.</p>Fórmula:C8H12MnN4S8ZnPureza:98%Cor e Forma:Grayish-Yellow PowderPeso molecular:541.08Olsalazine
CAS:<p>Olsalazine (Dipentium), an anti-inflammatory drug, is used in the treatment of inflammatory bowel disease. It is also a novel DNA hypomethylating agent.</p>Fórmula:C14H10N2O6Pureza:99.31%Cor e Forma:SolidPeso molecular:302.24SEC inhibitor KL-1
CAS:<p>KL-1, a potent SEC inhibitor, disrupts the AFF4-CCNT1 interaction with a Ki of 3.48 μM, selectively targeting the SEC.</p>Fórmula:C18H16ClNO4Pureza:97.42%Cor e Forma:SolidPeso molecular:345.78WYE-354
CAS:<p>WYE-354 is a selective mTOR inhibitor (IC50=5 nM), targeting mTORC1/C2 over PI3Kα (>100x) and PI3Kγ (>500x), sparing P-AKT(T308).</p>Fórmula:C24H29N7O5Pureza:97.86% - 99.61%Cor e Forma:SolidPeso molecular:495.53EF24
CAS:<p>EF24 treatment boosts caspase 3/9 activity, hinders MEK1/ERK phosphorylation, and exhibits strong anti-tumor effects in OSCC by deactivating MAPK/ERK.</p>Fórmula:C19H15F2NOPureza:99.71%Cor e Forma:SolidPeso molecular:311.33Deferitrin
CAS:<p>Deferitrin (GT-56-252) is an iron chelator. It potentially for the treatment of thalassemia and iron overload.</p>Fórmula:C11H11NO4SPureza:98.71%Cor e Forma:SolidPeso molecular:253.27Simazine
CAS:<p>Simazine (Tafazine), a chlorotriazine herbicide/pesticide, may cause reproductive harm, endocrine disruption, and cancer.</p>Fórmula:C7H12ClN5Pureza:99.82%Cor e Forma:SolidPeso molecular:201.66McMMAF
CAS:<p>McMMAF is a protective group-conjugated MMAF.</p>Fórmula:C49H76N6O11Pureza:99.65% - >99.99%Cor e Forma:SolidPeso molecular:925.16Sophocarpine
CAS:<p>Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Fórmula:C15H22N2OPureza:99.89%Cor e Forma:SolidPeso molecular:246.35
