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Apoptose

Apoptose

Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.

Subcategorias de "Apoptose"

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Foram encontrados 5599 produtos de "Apoptose"

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  • NSC-639829

    CAS:
    <p>NSC-639829 is an anti-tumor compound that requires a solubilizing agent for dissolution.</p>
    Fórmula:C21H20BrN5O3
    Pureza:99.53% - 99.77%
    Cor e Forma:Solid
    Peso molecular:470.32
  • CCT373566

    CAS:
    <p>CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro &amp; shrinks tumors in vivo.</p>
    Fórmula:C26H29ClF2N6O3
    Cor e Forma:Solid
    Peso molecular:547
  • Apoptotic agent-3

    CAS:
    <p>"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."</p>
    Fórmula:C31H21N5OS
    Cor e Forma:Solid
    Peso molecular:511.6
  • QTX125

    CAS:
    <p>QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.</p>
    Fórmula:C23H19N3O5
    Cor e Forma:Solid
    Peso molecular:417.41
  • Topoisomerase II inhibitor 7

    CAS:
    <p>Topoisomerase II inhibitor 7 halts cell division and induces apoptosis, targeting topoisomerase II alpha with a 3.19 μM IC50.</p>
    Fórmula:C32H28BrN5O5S
    Cor e Forma:Solid
    Peso molecular:674.56
  • ATX inhibitor 13

    CAS:
    <p>ATX inhibitor 13: orally active, IC50 3.4 nM, halts RAW264.7 cells at G2, curbs growth/migration, prompts apoptosis, suppresses tumors.</p>
    Fórmula:C31H35Cl2N5O3
    Cor e Forma:Solid
    Peso molecular:596.55
  • A-385358

    CAS:
    <p>A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.</p>
    Fórmula:C32H41N5O5S2
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:639.83
  • PIK-C98

    CAS:
    <p>PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.</p>
    Fórmula:C16H10Cl2N2OS
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:349.23
  • p53 Activator 5

    CAS:
    <p>Potent p53 Activator 5, SC150 &lt;0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>
    Fórmula:C29H32F6N4O
    Cor e Forma:Solid
    Peso molecular:566.58
  • Metoprolol fumarate

    CAS:
    <p>Metoprolol fumarate (CGP 2175C): selective β1-blocker with anti-inflammatory, antitumor, anti-angiogenic effects.</p>
    Fórmula:C34H54N2O10
    Cor e Forma:Solid
    Peso molecular:650.8
  • Shield-2

    CAS:
    <p>Shield-2 is a potent FKBP-derived destabilizing domain stabilizing ligand.</p>
    Fórmula:C35H51N3O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:625.8
  • MMP2-IN-1

    CAS:
    <p>MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.</p>
    Fórmula:C15H13NO5S
    Cor e Forma:Solid
    Peso molecular:319.33
  • Quinidine polygalacturonate

    CAS:
    <p>Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.</p>
    Fórmula:C26H34N2O9
    Cor e Forma:Solid
    Peso molecular:518.22643
  • ZT55

    CAS:
    <p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>
    Fórmula:C17H16N2O3
    Cor e Forma:Solid
    Peso molecular:296.32
  • BLM-IN-2


    <p>BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.</p>
    Fórmula:C33H38BrFN4O
    Cor e Forma:Solid
    Peso molecular:605.58
  • SIRT6 activator 12q

    CAS:
    <p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>
    Fórmula:C31H22N2O2
    Cor e Forma:Solid
    Peso molecular:454.52
  • CEP-1612

    CAS:
    <p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>
    Fórmula:C35H53N7O7
    Cor e Forma:Solid
    Peso molecular:683.84
  • SKLB0565

    CAS:
    <p>SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.</p>
    Fórmula:C20H25ClN6O
    Cor e Forma:Solid
    Peso molecular:400.91
  • S-Gem

    CAS:
    <p>S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.</p>
    Fórmula:C13H15F2N3O6S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:411.4
  • Selicrelumab

    CAS:
    <p>Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.</p>
    Pureza:98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)
    Cor e Forma:Liquid
  • Antiproliferative agent-7

    CAS:
    <p>Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.</p>
    Fórmula:C28H32N4O
    Cor e Forma:Solid
    Peso molecular:440.58
  • AG-024322

    CAS:
    <p>AG-024322 is a pan-CDK inhibitor with antitumor activity, induces apoptosis, and can be used in the study of metabolic diseases.</p>
    Fórmula:C23H20F2N6
    Pureza:98.53%
    Cor e Forma:Solid
    Peso molecular:418.44
  • SKLB70326

    CAS:
    <p>SKLB70326 is a cell-cycle progression inhibitor that acts by inducing G0/G1 phase arrest and apoptosis in human hepatic carcinoma cells.</p>
    Fórmula:C15H13N3O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:299.35
  • PDE5-IN-3

    CAS:
    <p>PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.</p>
    Fórmula:C21H14BrN5O2
    Cor e Forma:Solid
    Peso molecular:448.27
  • Dipin

    CAS:
    <p>Dipin is an Antineoplastic.</p>
    Fórmula:C12H24N6O2P2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:346.31
  • PHA-690509

    CAS:
    <p>PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.</p>
    Fórmula:C17H21N3O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:331.43
  • Antitumor agent-83


    <p>Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.</p>
    Fórmula:C29H30N6O2
    Cor e Forma:Solid
    Peso molecular:494.59
  • Atopaxar

    CAS:
    <p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>
    Fórmula:C29H38FN3O5
    Pureza:97.07% - 98.07%
    Cor e Forma:Solid
    Peso molecular:527.63
  • CAY10506

    CAS:
    <p>CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.</p>
    Fórmula:C20H26N2O4S3
    Cor e Forma:Solid
    Peso molecular:454.63
  • PhiKan 083 hydrochloride

    CAS:
    <p>PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).</p>
    Fórmula:C16H19ClN2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:274.79
  • Mutant p53 modulator-1

    CAS:
    <p>Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.</p>
    Fórmula:C27H32F4N8O2
    Cor e Forma:Solid
    Peso molecular:576.59
  • FKGK 18

    CAS:
    <p>FKGK 18: GVIA iPLA2 inhibitor, 99.9% at 0.091 fraction, selective, IC50 ~50 nM–3 μM, reduces blood glucose and diabetes in NOD mice.</p>
    Fórmula:C16H15F3O
    Cor e Forma:Solid
    Peso molecular:280.28
  • QM31

    CAS:
    <p>QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).</p>
    Fórmula:C39H38Cl4N4O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:768.56
  • RIP1 kinase inhibitor 6

    CAS:
    <p>RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1</p>
    Fórmula:C19H18F2N2O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:360.35
  • EGFR-IN-59

    CAS:
    <p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>
    Fórmula:C27H23N5O4S
    Cor e Forma:Solid
    Peso molecular:513.57
  • RET-IN-8

    CAS:
    <p>RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>
    Fórmula:C27H30N6O3
    Cor e Forma:Solid
    Peso molecular:486.57
  • Sanazole

    CAS:
    <p>Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line.</p>
    Fórmula:C7H11N5O4
    Cor e Forma:Solid
    Peso molecular:229.19
  • AZD-5991 Racemate

    CAS:
    <p>AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.</p>
    Fórmula:C35H34ClN5O3S2
    Cor e Forma:Solid
    Peso molecular:672.26
  • Mcl1-IN-11

    CAS:
    <p>Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.</p>
    Fórmula:C38H41N3O5S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:683.88
  • DX2-201

    CAS:
    <p>DX2-201 is a potent and selective inhibitor of oxidative phosphorylation (OXPHOS) complex I (IC50: 312 nM) and exhibits anticancer activity.</p>
    Fórmula:C18H28N2O6S2
    Cor e Forma:Solid
    Peso molecular:432.55
  • Declopramide

    CAS:
    <p>Declopramide (OXI-104) is a chemosensitizer with antitumor activity that can be used to study colorectal cancer and inflammatory bowel disease.</p>
    Fórmula:C13H20ClN3O
    Pureza:98.53%
    Cor e Forma:Solid
    Peso molecular:269.77
  • SB-218078

    CAS:
    <p>SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM).</p>
    Fórmula:C24H15N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:393.39
  • EGFR-IN-46

    CAS:
    <p>EGFR-IN-46: Potent EGFR/FAK inhibitor (IC50: 20.17 &amp; 14.25 nM), curbs cancer cell growth, triggers apoptosis.</p>
    Fórmula:C27H32F3N3O3
    Cor e Forma:Solid
    Peso molecular:503.56
  • Tubulin/HDAC-IN-1

    CAS:
    <p>Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin &amp; HDAC8, blocking polymerization &amp; targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.</p>
    Fórmula:C21H18N4O3
    Cor e Forma:Solid
    Peso molecular:374.39
  • PD-1/PD-L1-IN-14

    CAS:
    <p>PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM).</p>
    Fórmula:C24H24N4O2
    Cor e Forma:Solid
    Peso molecular:400.47
  • T-3256336

    CAS:
    <p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>
    Fórmula:C31H45F2N5O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:605.72
  • BTK-IN-9

    CAS:
    <p>BTK-IN-9 reversibly inhibits BTK, disrupts mitochondria, boosts ROS, and triggers apoptosis in Z138 cells, impeding condyloma cell growth.</p>
    Fórmula:C25H19N7O4
    Cor e Forma:Solid
    Peso molecular:481.46
  • Pentabromophenol

    CAS:
    <p>Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.</p>
    Fórmula:C6HBr5O
    Pureza:99.83%
    Cor e Forma:Monoclinic Prisms From Acetic Acid; Needles From Alcohol Physical Description Light Brown Powder Insoluble In Water (Ntp 1992)
    Peso molecular:488.59
  • RIPK1-IN-3

    CAS:
    <p>RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.</p>
    Fórmula:C22H19F3N6O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:472.42
  • Anti-inflammatory agent 11

    CAS:
    <p>Potent anti-inflammatory compound 16 combats tuberculosis, inhibiting Mtb H37Rv and M299 (MICs: 1.3, 6.9 μM) and reduces NO, TNF-α, IL-1β production.</p>
    Fórmula:C14H14N4OS
    Cor e Forma:Solid
    Peso molecular:286.35
  • DCP-LA

    CAS:
    <p>DCP-LA (FR236924), linoleic acid derivatives, selective and direct activation of PKCε.</p>
    Fórmula:C20H36O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:308.5
  • MCL-1/BCL-2-IN-4

    CAS:
    <p>MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.</p>
    Fórmula:C26H23BrN2O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:555.44
  • EL-102

    CAS:
    <p>EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.</p>
    Fórmula:C19H16N2O3S2
    Pureza:99.34%
    Cor e Forma:Solid
    Peso molecular:384.47
  • Irbesartan HCl

    CAS:
    <p>Irbesartan: angiotensin II blocker; treats hypertension by inhibiting receptor binding.</p>
    Fórmula:C25H29ClN6O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:465
  • (E)-[6]-Dehydroparadol

    CAS:
    <p>(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.</p>
    Fórmula:C17H24O3
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:276.37
  • K-7174 dihydrochloride

    CAS:
    <p>K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-</p>
    Fórmula:C33H50Cl2N2O6
    Pureza:99.15%
    Cor e Forma:Solid
    Peso molecular:641.67
  • PARP14 inhibitor H10

    CAS:
    <p>PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nM</p>
    Fórmula:C24H27N7O7S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:557.58
  • DJ001

    CAS:
    <p>DJ001: specific PTPσ inhibitor, non-competitive, IC50=1.43 μM, aids hematopoietic stem cell regeneration.</p>
    Fórmula:C15H12N2O3
    Pureza:99.54%
    Cor e Forma:Solid
    Peso molecular:268.27
  • CDK8/19-IN-1

    CAS:
    <p>CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).</p>
    Fórmula:C19H18N4O4S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:430.5
  • Psammaplysene A

    CAS:
    <p>Psammaplysene A is a FOXO1a nuclear export inhibitor.</p>
    Fórmula:C27H35Br4N3O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:769.2
  • W146 TFA

    CAS:
    <p>W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.</p>
    Fórmula:C18H28F3N2O6P
    Cor e Forma:Solid
    Peso molecular:456.399
  • VII-31

    CAS:
    <p>VII-31 is an activator of the NEDDylation pathway, capable of inducing apoptosis in MCF-7, PC-3, and MGC-803 cells.</p>
    Fórmula:C23H25NO5S
    Cor e Forma:Solid
    Peso molecular:427.51
  • MYRA-A

    CAS:
    <p>MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.</p>
    Fórmula:C19H20N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:340.37
  • Polyphyllin II

    CAS:
    <p>Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.</p>
    Fórmula:C44H70O16
    Pureza:99.92%
    Cor e Forma:Solid
    Peso molecular:855.02
  • Epirubicin

    CAS:
    <p>Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.</p>
    Fórmula:C27H29NO11
    Cor e Forma:Solid
    Peso molecular:543.52
  • SLMP53-2

    CAS:
    <p>SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction with</p>
    Fórmula:C26H22N2O2
    Cor e Forma:Solid
    Peso molecular:394.47
  • Misetionamide

    CAS:
    <p>Misetionamide: Oral oxathiazin-like, GAPDH inhibitor with anticancer properties for research use.</p>
    Fórmula:C3H7NO3S
    Cor e Forma:Solid
    Peso molecular:137.16
  • pan-HER-IN-1

    CAS:
    <p>Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.</p>
    Fórmula:C19H14BrN5O
    Cor e Forma:Solid
    Peso molecular:408.25
  • MpsBAY2a

    CAS:
    <p>carcinoma cell proliferation.</p>
    Fórmula:C29H28N6O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:476.57
  • TH1834 dihydrochloride

    CAS:
    <p>TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.</p>
    Fórmula:C33H42Cl2N6O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:641.63
  • MBM-17

    CAS:
    <p>MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).</p>
    Fórmula:C28H28N6O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:480.56
  • NSC405640

    CAS:
    <p>NSC405640 selectively inhibits MDM2-p53 interaction, restoring mutated p53 structure; halts growth of cells with normal p53. [1]</p>
    Fórmula:C12H10Cl2Sn
    Cor e Forma:Solid
    Peso molecular:343.82
  • ML132

    CAS:
    <p>ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).</p>
    Fórmula:C22H28ClN5O5
    Cor e Forma:Solid
    Peso molecular:477.94
  • KY1022

    CAS:
    <p>KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.</p>
    Fórmula:C17H19N3OS
    Cor e Forma:Solid
    Peso molecular:313.42
  • Jolkinolide B

    CAS:
    <p>Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.</p>
    Fórmula:C20H26O4
    Pureza:99.39% - 99.7%
    Cor e Forma:Solid
    Peso molecular:330.42
  • HL271

    CAS:
    <p>HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.</p>
    Fórmula:C13H17ClF3N5O
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:351.76
  • Topoisomerase IIα-IN-3

    CAS:
    <p>Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.</p>
    Fórmula:C29H20N6O2S
    Cor e Forma:Solid
    Peso molecular:516.57
  • Glucocorticoid receptor modulator 1

    CAS:
    <p>Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.</p>
    Fórmula:C24H23ClN2O4S
    Pureza:99.79%
    Cor e Forma:Solid
    Peso molecular:470.97
  • EGFR-IN-56

    CAS:
    <p>EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.</p>
    Fórmula:C23H22N4O3S
    Cor e Forma:Solid
    Peso molecular:434.51
  • Adapalene sodium salt

    CAS:
    <p>Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist.</p>
    Fórmula:C28H28NaO3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:435.519
  • CDK1/2/4-IN-1

    CAS:
    <p>CDK1/2/4-IN-1 inhibits CDKs (IC50: CDK1-1.47μM; CDK2-0.78μM; CDK4-0.87μM) and is useful in cancer studies, affecting apoptosis and the cell cycle.</p>
    Fórmula:C15H16N2O2S
    Cor e Forma:Solid
    Peso molecular:288.36
  • ACA-28

    CAS:
    <p>ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.</p>
    Fórmula:C17H16O6
    Pureza:98.73%
    Cor e Forma:Solid
    Peso molecular:316.31
  • HS-438

    CAS:
    <p>HS-438 inhibits imatinib-resistant BCR-ABL T315I mutation in chronic myeloid leukemia.</p>
    Fórmula:C17H17N3O3S
    Cor e Forma:Solid
    Peso molecular:343.4
  • Anti-inflammatory agent 17

    CAS:
    <p>Compound 17: Orally active, potent IL-6 &amp; TNF-α inhibitor; not cytotoxic; promising for ALI research.</p>
    Fórmula:C20H23NO5
    Cor e Forma:Solid
    Peso molecular:357.4
  • HDACs/mTOR Inhibitor 1

    CAS:
    <p>HDACs/mTOR Inhibitor 1 is a dual HDACs and mammalian target of Rapamycin (mTOR) target inhibitor for treating hematologic malignancies (IC50s: 0.19 nM, 1.8 nM,</p>
    Fórmula:C28H38N8O5
    Cor e Forma:Solid
    Peso molecular:566.65
  • SKI-I

    CAS:
    <p>SKI-I: Human sphingosine kinase inhibitor, IC50 1.2μM; hERK2 inhibitor, IC50 11μM; promotes tumor cell apoptosis.</p>
    Fórmula:C25H18N4O2
    Cor e Forma:Solid
    Peso molecular:406.44
  • SID 3712249

    CAS:
    <p>SID 3712249 is an inhibitor of the biogenesis of microRNA-544 (miR-544).</p>
    Fórmula:C17H21N7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:323.4
  • PD-1/PD-L1-IN-28

    CAS:
    <p>PD-1/PD-L1-IN-28, an inhibitor of the PD-1/PD-L1 signaling pathway (IC 50 = 0.744 µM), demonstrates promising research potential in tumor immunity.</p>
    Fórmula:C24H24N4O2
    Cor e Forma:Solid
    Peso molecular:400.47
  • Epinephrine bitartrate

    CAS:
    <p>L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.</p>
    Fórmula:C13H19NO9
    Pureza:98.6% - 99.07%
    Cor e Forma:White Solid
    Peso molecular:333.3
  • Caspase-3-IN-1

    CAS:
    <p>Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).</p>
    Fórmula:C26H25N3O6S
    Cor e Forma:Solid
    Peso molecular:507.56
  • Telomerase-IN-4

    CAS:
    <p>Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].</p>
    Fórmula:C21H18N4OS2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:406.52
  • SS28

    CAS:
    <p>SS28 inhibits tubulin polymerization to cause cell cycle arrest at G2/M phase.</p>
    Fórmula:C18H20O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:284.35
  • Anticancer agent 147

    CAS:
    <p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>
    Fórmula:C32H40BrN3O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:578.58
  • FW1256

    CAS:
    <p>FW1256: phenyl analog, slow H2S donor, inhibits NF-κB, induces apoptosis, anti-inflammatory, potential cancer/cardio treatment.</p>
    Fórmula:C12H10NOPS
    Cor e Forma:Solid
    Peso molecular:247.25
  • Antiproliferative agent-32

    CAS:
    <p>Antiproliferative agent-32 (Compound 1c) impedes phosphorylation within the PI3K/Akt/mTOR signaling pathway, restrains proliferation of Huh7 and SK-Hep-1 cells</p>
    Fórmula:C19H15NO2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:289.33
  • Atopaxar Hydrobromide

    CAS:
    <p>Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>
    Fórmula:C29H39BrFN3O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:608.54
  • Antitumor agent-115

    CAS:
    <p>Antitumor agent-115 (SS-12) is a potent anti-tumor compound, exhibiting an IC50 range of 0.34 μM-24.14 μM against the 4T1 mouse breast cancer cell line.</p>
    Fórmula:C19H38ClNO2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:347.96
  • 2,5-Dihydroxybiphenyl

    CAS:
    <p>2,5-Dihydroxybiphenyl: a small molecule that induces trichothiodystrophy A protein dimerization, modulating TFIIH activity.</p>
    Fórmula:C12H10O2
    Pureza:99.66%
    Cor e Forma:White To Grey-Brownish Powder
    Peso molecular:186.21
  • Anticancer agent 59


    <p>Anticancer agent 59 suppresses various cancers, notably A549 at IC50 of 0.2 μM, induces apoptosis and disrupts mitochondria in mice.</p>
    Fórmula:C42H59NO6
    Cor e Forma:Solid
    Peso molecular:673.92
  • 673-A

    CAS:
    <p>673-A inhibits ALDH1A, depletes ovarian CSCs, induces necroptosis, and reverses chemo resistance.</p>
    Fórmula:C15H13NO
    Cor e Forma:Solid
    Peso molecular:223.27