Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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5HPP-33
CAS:<p>5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.</p>Fórmula:C20H21NO3Cor e Forma:SolidPeso molecular:323.39RET-IN-20
<p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>Fórmula:C32H33FN6O4Cor e Forma:SolidPeso molecular:584.64DAT-230
CAS:<p>DAT-230 is a microtubule inhibitor effective against cancer cells, causing cell cycle arrest and apoptosis via caspase activation.</p>Fórmula:C20H21NO2SCor e Forma:SolidPeso molecular:339.45Topoisomerase I inhibitor 3
CAS:<p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>Fórmula:C18H14FNO3Cor e Forma:SolidPeso molecular:311.31PI3Kδ-IN-10
CAS:<p>PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).</p>Fórmula:C19H16ClN9Cor e Forma:SolidPeso molecular:405.84Caspase-9 Inhibitor III
CAS:<p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>Fórmula:C24H35ClN6O9Cor e Forma:SolidPeso molecular:587.02HLI 373
CAS:<p>HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.</p>Fórmula:C18H23N5O2Cor e Forma:SolidPeso molecular:341.41Quinidine Monosulfate
CAS:<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Fórmula:C40H50N4O8SCor e Forma:SolidPeso molecular:746.92Anticancer agent 67
CAS:<p>Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.</p>Fórmula:C26H24F2N6O2S2Cor e Forma:SolidPeso molecular:554.63Benpyrine
CAS:<p>Benpyrine, an oral TNF-α inhibitor (KD 82.1 μM, IC50 0.109 μM), may help in inflammatory/autoimmune studies.</p>Fórmula:C16H16N6OCor e Forma:SolidPeso molecular:308.34EGFR-IN-52
CAS:<p>EGFR-IN-52, a potent EGFR inhibitor, has IC50s: 0.358 μM (wild-type), 86.02 μM (L858R-TK), 432.67 μM (T790M-TK); induces cancer cell apoptosis.</p>Fórmula:C19H18N4O3SCor e Forma:SolidPeso molecular:382.44SPRC
CAS:<p>"SPRC, a synthetic antioxidant, boosts H2S production, activates STAT3, and guards against doxorubicin heart damage."</p>Fórmula:C6H9NO2SPureza:98%Cor e Forma:SolidPeso molecular:159.21RGB-286147
CAS:<p>RGB-286147 is a potent, selective, ATP-competitive Cdks inhibitor.</p>Fórmula:C23H22Cl2N4O3Pureza:98%Cor e Forma:SolidPeso molecular:473.35(R)-eIF4A3-IN-2
CAS:<p>(R)-eIF4A3-IN-2, a weaker eIF4A3-IN-2 isomer, inhibits eIF4A3 selectively with 110 nM IC50.</p>Fórmula:C25H19Br2ClN4O2Cor e Forma:SolidPeso molecular:602.71CAY10789
CAS:<p>CAY10789: potent CysLT1R antagonist (IC50 2.8 µM), GPBAR1 agonist (EC50 3 µM), reduces U937 cell adhesion, TNF-α, stable with promising pharmacokinetics.</p>Fórmula:C17H15NO2Cor e Forma:SolidPeso molecular:265.31Caspase-3/7 activator 3
<p>Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.</p>Fórmula:C24H27NO5Cor e Forma:SolidPeso molecular:409.47Anticancer agent 63
CAS:<p>Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.</p>Fórmula:C17H24F3NOSeCor e Forma:SolidPeso molecular:394.33Cyclamidomycin
CAS:<p>Cyclamidomycin is an antibiotic. It also functions as an inhibitor of nucleoside diphosphokinase of Escherichia coli.</p>Fórmula:C7H10N2OCor e Forma:SolidPeso molecular:138.17YL-939
<p>YL-939 is a potent inhibitor of ferroptosis, targeting the PHB2/ferritin/iron axis to impede this form of cell death.</p>Fórmula:C25H26N6OCor e Forma:SolidPeso molecular:426.51VS 8
CAS:<p>VS 8: potent oral VEGFR-2 inhibitor, anti-angiogenic, induces cancer cell apoptosis & migration, acts on CSCs.</p>Fórmula:C26H20F3N3O3Cor e Forma:SolidPeso molecular:479.45VEGFR-2-IN-28
CAS:<p>VEGFR-2-IN-28 is a potent inhibitor of VEGFR-2 (IC50: 0.83 μM). VEGFR-2-IN-28 induces apoptosis and exhibits antitumor effects.</p>Fórmula:C26H17N7O7Cor e Forma:SolidPeso molecular:539.46PK9327
CAS:<p>PK9327 is a small-molecule stabilizer that targets cavity-creating p53 cancer mutations.</p>Fórmula:C21H22N2SCor e Forma:SolidPeso molecular:334.48MMP-9-IN-5
CAS:<p>MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.</p>Fórmula:C27H20IN3O4Cor e Forma:SolidPeso molecular:577.37Gemcitabine monophosphate
CAS:<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Fórmula:C9H12F2N3O7PCor e Forma:SolidPeso molecular:343.18CDK9-IN-18
CAS:<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Fórmula:C27H20N8OCor e Forma:SolidPeso molecular:472.5SCAL-266
CAS:<p>SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.</p>Fórmula:C27H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:511.54VU0424465
CAS:<p>VU0424465 is a mGlu5-selective allosteric agonist.</p>Fórmula:C19H19FN2O2Cor e Forma:SolidPeso molecular:326.36AZD 1152 (hydrochloride)
CAS:<p>AZD 1152, an oral prodrug, becomes AZD 1152-HQPA in plasma, selectively inhibits Aurora kinase B (IC50=0.36 nM), and blocks tumor growth.</p>Fórmula:C26H33Cl2FN7O6PCor e Forma:SolidPeso molecular:660.47GW-3333
CAS:<p>GW-3333 inhibits matrix metalloproteinases and TNF-Converting Enzyme, showing potential as an antiarthritic therapy.</p>Fórmula:C22H36N4O4Pureza:98%Cor e Forma:SolidPeso molecular:420.55PBENZ-DBRMD
CAS:<p>PBENZ-DBRMD inhibits DIO3, has anti-growth effects, and aids apoptosis, showing promise for cancer research.</p>Fórmula:C11H5Br2NO4Cor e Forma:SolidPeso molecular:374.97SB-218078
CAS:<p>SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM).</p>Fórmula:C24H15N3O3Pureza:98%Cor e Forma:SolidPeso molecular:393.39Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Fórmula:C26H23NOCor e Forma:SolidPeso molecular:365.47Tubulin/MMP-IN-2
CAS:<p>Tubulin/MMP-IN-2 blocks tubulin polymerization, MMP-2/-3/-9, induces apoptosis, aids cancer research, IC50: 24.95, 31.60, 22.37 µM.</p>Fórmula:C40H48NO11PCor e Forma:SolidPeso molecular:749.78TPB15
CAS:<p>TPB15, an oral Hh inhibitor, blocks Smo activity, arrests cell cycle, induces apoptosis, and shows potent antitumor effects with low toxicity.</p>Fórmula:C18H9Cl4N5OCor e Forma:SolidPeso molecular:453.11(Z)-4EGI-1
CAS:<p>(Z)-4EGI-1, a Z-isomer, inhibits eIF4E/eIF4G; binds eIF4E (IC50=43.5 μM, Kd=8.74 μM); anticancer properties.</p>Fórmula:C18H12Cl2N4O4SCor e Forma:SolidPeso molecular:451.28Bcl-2/Mcl-1-IN-1
CAS:<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Fórmula:C28H23NO3Cor e Forma:SolidPeso molecular:421.49EGFR/HER2/TS-IN-1
CAS:<p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>Fórmula:C24H15N5O4S2Cor e Forma:SolidPeso molecular:501.54Anticancer agent 99
CAS:<p>Anticancer agent 99 targets HepG2 cells, IC50 at 35.9 μM, induces apoptosis and hinders cell growth.</p>Fórmula:C19H20F3N3O2Cor e Forma:SolidPeso molecular:379.38Thioxodihydroquinazolinone-19
CAS:<p>Thioxodihydroquinazolinone-19 triggers apoptosis in A2780cis ovarian cancer cells and enhances cisplatin efficacy.</p>Fórmula:C16H14N2OSPureza:98%Cor e Forma:SolidPeso molecular:282.36hnRNPK-IN-1
CAS:<p>hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.</p>Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43GK563
CAS:<p>GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.</p>Fórmula:C16H22O2Cor e Forma:SolidPeso molecular:246.34Mps1-IN-5
CAS:<p>Mps1-IN-5: oral Mps1 inhibitor with 29 nM IC50, induces apoptosis, G2/M arrest, and has anti-tumor properties.</p>Fórmula:C24H25N9Cor e Forma:SolidPeso molecular:439.52Isodispar B
CAS:<p>Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.</p>Fórmula:C20H18O5Cor e Forma:SolidPeso molecular:338.35Justicidin B
CAS:<p>Justicidin B: anticancer, proapoptotic, inhibits bone resorption & platelets, antiviral, fungicidal, antiprotozoal.</p>Fórmula:C21H16O6Cor e Forma:SolidPeso molecular:364.35NBI-42902
CAS:<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Fórmula:C27H24F3N3O3Cor e Forma:SolidPeso molecular:495.49CU-3
CAS:<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Fórmula:C16H12N2O4S3Pureza:98%Cor e Forma:SolidPeso molecular:392.47DRAK1/2-IN-1
CAS:<p>DRAK1/2-IN-1 is a potent inhibitor targeting both DRAK1 and DRAK2, displaying dissociation constants (Kd) of 1 µM and 6 µM, respectively.</p>Fórmula:C22H24N2O3SCor e Forma:SolidPeso molecular:396.5ISC-4
CAS:<p>ISC-4 is an Akt inhibitor, which activates prostate apoptosis response protein-4 and reduces colon tumor growth in a nude mouse model.</p>Fórmula:C11H13NSeCor e Forma:SolidPeso molecular:238.19RIPK1-IN-11
CAS:<p>RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.</p>Fórmula:C23H24N4O4SCor e Forma:SolidPeso molecular:452.53CX-5011
CAS:<p>CX-5011, a CK2 inhibitor, induces Rac1 activation and promotes apoptosis, effectively causing cancer cell death [1] [2].</p>Fórmula:C20H12N4O2Pureza:98%Cor e Forma:SolidPeso molecular:340.33Apogossypolone (ApoG2)
CAS:<p>Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i</p>Fórmula:C28H26O8Cor e Forma:SolidPeso molecular:490.5PARP1/BRD4-IN-1
CAS:<p>PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.</p>Fórmula:C29H26N6O3Cor e Forma:SolidPeso molecular:506.56PERK-IN-5
CAS:<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5Tubulin polymerization-IN-17
CAS:<p>Compound 23g, a potent inhibitor of tubulin aggregation, induces apoptosis, and inhibits cell migration; promising for cancer research.</p>Fórmula:C26H23NO5Cor e Forma:SolidPeso molecular:429.46Ludartin
CAS:<p>Ludartin activates TRPA1, induces DNA damage, and lowers mitochondrial potential, yielding anticancer effects.</p>Fórmula:C15H18O3Cor e Forma:SolidPeso molecular:246.3EGFR-IN-57
CAS:<p>EGFR-IN-57: potent EGFR-TK blocker, IC50 0.054 μM, oral. Halts VEGFR-2, CK2α, topo IIβ, tubulin. Causes G2/M, pre-G1 arrest, cancer cell death.</p>Fórmula:C22H15N3O2SCor e Forma:SolidPeso molecular:385.44Metallo-β-lactamase-IN-5
CAS:<p>Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs).</p>Fórmula:C19H16N4O3Cor e Forma:SolidPeso molecular:348.36HDAC1/6-IN-1
CAS:<p>HDAC1/6-IN-1, a dual HDAC1 (89 nM) and HDAC6 (13 nM) inhibitor, blocks cancer cell cycle, triggers apoptosis, and halts metastasis.</p>Fórmula:C32H45N7O4Cor e Forma:SolidPeso molecular:591.74AG311
CAS:<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Fórmula:C17H15N5SCor e Forma:SolidPeso molecular:321.4CZS-241
<p>CZS-241: Oral PLK4 inhibitor (IC50=2.6 nM), less potent TRKA blocker (IC50=2.74 μM), triggers apoptosis and S/G2 arrest, anti-leukemia, safe for normal cells.</p>Fórmula:C26H24ClF2N9OCor e Forma:SolidPeso molecular:551.98AP23464
CAS:<p>AP23464 inhibits Src/Abl kinases, effective on imatinib-resistant CML cells (IC50=14nM), blocks cell cycle, induces apoptosis, not against T315I mutant.</p>Fórmula:C26H30N5O2PCor e Forma:SolidPeso molecular:475.52Antitumor agent-57
CAS:<p>Antitumor agent-57 (Compound 3o) is a potent NQO1-directed antitumor compound.</p>Fórmula:C20H15NO5Cor e Forma:SolidPeso molecular:349.34CMC2.24
CAS:<p>CMC2.24 inhibits Ras and ERK1/2, fights pancreatic tumors in mice, blocks MMPs (IC50: 2-69 µM), and reduces osteoarthritis by stabilizing cartilage.</p>Fórmula:C26H21NO5Cor e Forma:SolidPeso molecular:427.45PI3K-IN-33
CAS:<p>PI3K-IN-33 selectively inhibits PI3K-α/β/δ, blocks G2/M, induces apoptosis, for leukemia research.</p>Fórmula:C23H21BrN6O2Cor e Forma:SolidPeso molecular:493.36PI3Kδ-IN-11
CAS:<p>PI3Kδ-IN-11 is a potent and selective PI3Kδ inhibitor (IC50: 27.5 nM) that dose-dependently blocks PI3K/Akt pathway activity.</p>Fórmula:C27H21N5OCor e Forma:SolidPeso molecular:431.49(Rac)-Indoximod
CAS:<p>(Rac)-Indoximod, a robust IDO inhibitor, and IFN-γ combo reduce α-SMA hCM activity and boost apoptosis, aiding cardiac fibrosis.</p>Fórmula:C12H14N2O2Cor e Forma:SolidPeso molecular:218.25(S)-Erypoegin K
CAS:<p>(S)-Erypoegin K is a potent anticancer agent that demonstrates strong anti-proliferative activity against HL-60 cells and induces apoptosis.</p>Fórmula:C20H18O6Cor e Forma:SolidPeso molecular:354.35Anticancer agent 56
CAS:<p>Anticancer agent 56 (4d) has potent action <3μM IC50 on various cancers, causing G2/M arrest and mitochondrial apoptosis via ROS and caspase activation.</p>Fórmula:C20H18ClN3O3Cor e Forma:SolidPeso molecular:383.83Bcl-2/Mcl-1-IN-3
CAS:<p>Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.</p>Fórmula:C27H26ClNO4Cor e Forma:SolidPeso molecular:463.95GGTI-2154
CAS:<p>GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity against</p>Fórmula:C24H28N4O3Cor e Forma:SolidPeso molecular:420.5PQ1 Succinate
CAS:<p>PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.</p>Fórmula:C25H28F3N3O6Cor e Forma:SolidPeso molecular:523.5NSC114792
CAS:<p>NSC114792 is a selective JAK3 inhibitor.</p>Fórmula:C26H32N4O2SPureza:98%Cor e Forma:SolidPeso molecular:464.62Mcl1-IN-3
CAS:<p>Mcl1-IN-3 is an Mcl1 inhibitor. It has an IC50 and Ki of 0.67 and 0.13 μM, respectively.</p>Fórmula:C27H22ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:487.93Antiproliferative agent-7
CAS:<p>Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.</p>Fórmula:C28H32N4OCor e Forma:SolidPeso molecular:440.58S-Gem
CAS:<p>S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.</p>Fórmula:C13H15F2N3O6S2Pureza:98%Cor e Forma:SolidPeso molecular:411.4p-nitro-Pifithrin-α
CAS:<p>p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.</p>Fórmula:C15H16BrN3O3SCor e Forma:SolidPeso molecular:398.27Anticancer agent 72
CAS:<p>Compound 8c inhibits K+ channel and induces apoptosis, showing promise as an anticancer agent.</p>Fórmula:C20H19N7O2Cor e Forma:SolidPeso molecular:389.41SKLB0565
CAS:<p>SKLB0565 inhibits tubulin and colorectal cancer growth (IC50: 0.012-0.081 μM), causes G2/M arrest, triggers apoptosis, and prevents HUVEC migration.</p>Fórmula:C20H25ClN6OCor e Forma:SolidPeso molecular:400.91CEP-1612
CAS:<p>CEP-1612 inhibits protein breakdown, regulates cell cycles, apoptosis, boosts p21/p27 expression, and curbs lung cancer growth.</p>Fórmula:C35H53N7O7Cor e Forma:SolidPeso molecular:683.84SIRT6 activator 12q
CAS:<p>SIRT6 activator 12q: potent, selective, oral; IC50 - SIRT1: 171.20μM, SIRT6: 0.58μM; halts cell growth/migration, induces apoptosis, G2 arrest, anticancer.</p>Fórmula:C31H22N2O2Cor e Forma:SolidPeso molecular:454.52BLM-IN-2
<p>BLM-IN-2: BLM inhibitor, IC50=0.8 μM; hinders CRC cell growth, invasion, cycle arrest, and death.</p>Fórmula:C33H38BrFN4OCor e Forma:SolidPeso molecular:605.58DBIBB
CAS:<p>DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.</p>Fórmula:C23H20N2O6SPureza:98.49% - 99.1%Cor e Forma:SolidPeso molecular:452.48Topoisomerase II inhibitor 10
CAS:<p>Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM).</p>Fórmula:C27H20N6O7SCor e Forma:SolidPeso molecular:572.55Alteminostat
CAS:<p>Alteminostat is used as a histone deacetylase inhibitor and is an antineoplastic drug candidate.</p>Fórmula:C27H36N6O3Cor e Forma:SolidPeso molecular:492.61IDO1/TDO-IN-1
CAS:<p>IDO1/TDO-IN-1 (30) inhibits IDO1 (Ki=0.23μM) & TDO (Ki=0.73μM); induces apoptosis via Bcl-2/Bax.</p>Fórmula:C21H16O6Cor e Forma:SolidPeso molecular:364.35EGFR-IN-60
CAS:<p>EGFR-IN-60: oral anticancer drug, inhibits EGFR/JAK3, effective on H1975/A431 cells, promotes apoptosis.</p>Fórmula:C28H28Cl2N6OCor e Forma:SolidPeso molecular:535.47Antioxidant agent-5
CAS:<p>Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.</p>Fórmula:C24H24N6OCor e Forma:SolidPeso molecular:412.49LLP-3
CAS:<p>Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.</p>Fórmula:C32H23ClN2O4Cor e Forma:SolidPeso molecular:534.99c-Met-IN-14
CAS:<p>c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.</p>Fórmula:C34H38ClFN4O7SCor e Forma:SolidPeso molecular:701.2Anticancer agent 83
CAS:<p>Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.</p>Fórmula:C20H19N5OSCor e Forma:SolidPeso molecular:377.46ZC0101
CAS:<p>ZC0101: potent oral IDO1/TrxR inhibitor. IC50: 0.084/7.98 μM. Induces apoptosis, ROS in cancer cells.</p>Fórmula:C17H15N3O2Cor e Forma:SolidPeso molecular:293.32TH-Z835
CAS:<p>TH-Z835 is a selective inhibitor for the KRAS (G12D) mutation, demonstrating an inhibitory concentration (IC50) of 1.6 μM.</p>Fórmula:C30H38N6OPureza:98%Cor e Forma:SolidPeso molecular:498.66RO2468
CAS:<p>RO2468 is a potent and orally active inhibitor of the p53-MDM2.</p>Fórmula:C30H30Cl2FN5O4Pureza:98%Cor e Forma:SolidPeso molecular:614.49MMP2-IN-1
CAS:<p>MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.</p>Fórmula:C15H13NO5SCor e Forma:SolidPeso molecular:319.33Cadein1
<p>Cadein1, an isoquinolinium derivative, induces G2/M phase delay and caspase-dependent apoptosis in cancer cells lacking functional p53.</p>Fórmula:C33H48F2INO2Cor e Forma:SolidPeso molecular:655.64BMS-37
CAS:<p>BMS-37 is a novel inhibitor of PD-1/PD-L1 immune checkpoint.</p>Fórmula:C27H32N2O4Cor e Forma:SolidPeso molecular:448.55GEM144
CAS:<p>GEM144: oral POLA1/HDAC11 inhibitor; boosts p53, p21; halts G1/S cycle; triggers cell death.</p>Fórmula:C28H31NO5Cor e Forma:SolidPeso molecular:461.55ATSP-7041
CAS:<p>ATSP-7041 is a novel potent and selective dual inhibitor of mdm2 (ki = 0.9 nm) and mdmx (ki = 7 nm)</p>Fórmula:C87H125N17O21Cor e Forma:SolidPeso molecular:1745.02p53 Activator 5
CAS:<p>Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Fórmula:C29H32F6N4OCor e Forma:SolidPeso molecular:566.58SAHA-OH
CAS:<p>SAHA-OH selectively inhibits HDAC6 (IC50 = 23 nM) with 10-47x preference over HDACs 1, 2, 3, 8, and reduces inflammation and macrophage apoptosis.</p>Fórmula:C15H22N2O4Pureza:98%Cor e Forma:SolidPeso molecular:294.35
