Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
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LOM612
CAS:<p>LOM612 is a potent and specific FOXO relocator FOXO3a reporter protein endogenous FOXO3a and FOXO1 , down-regulates c-Myc and cyclin D1, anti-proliferative.</p>Fórmula:C13H10N2O2SCor e Forma:SolidPeso molecular:258.3NU-8165
CAS:<p>NU-8165 is an MDM2-p53 protein-protein interaction inhibitor.</p>Fórmula:C24H22ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:407.89(5Z,2E)-CU-3
CAS:<p>(5Z,2E)-CU-3 is a potent and selective inhibitor of DGKα isozyme with an IC50 value of 0.6 μM and inhibition of DGKα by competing ATP with a Km value of 0.48 mM</p>Fórmula:C16H12N2O4S3Pureza:99.02%Cor e Forma:SolidPeso molecular:392.47Sparfosic acid trisodium
CAS:<p>Sparfosic acid trisodium is a CAD (carbamoyl-phosphate synthetase 2) inhibitor and also an aspartate transcarbamoyl transferase inhibitor with antitumour</p>Fórmula:C6H9NNaO8PPureza:98%Cor e Forma:SolidPeso molecular:277.1MSN-125
CAS:<p>MSN-125 inhibits Bax/Bak apoptosis, protects neurons, prevents MOMP with IC50 of 4μM.</p>Fórmula:C36H38BrN3O6Pureza:98%Cor e Forma:SolidPeso molecular:688.61USP7-IN-4
CAS:<p>USP7-IN-4 is a non-competitive, potent and selective inhibitor of USP7, up-regulates p53 and p21, down-regulates MDM2,anti-proliferativity RS4;11 (leukemia) .</p>Fórmula:C29H34N6O3Pureza:98.27% - 99.09%Cor e Forma:SolidPeso molecular:514.62ROC-325
CAS:<p>ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.</p>Fórmula:C28H27ClN4OSPureza:99.26%Cor e Forma:SolidPeso molecular:503.06Targapremir-210
CAS:<p>Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.</p>Fórmula:C32H36N10O2Pureza:98%Cor e Forma:SolidPeso molecular:592.69EC359
CAS:<p>EC359 is a Leukemia Inhibitory Factor Receptor (LIFR) inhibitor with anticancer activity for the study of leukemia and endometrial cancer.</p>Fórmula:C36H38F2O2Pureza:98.11% - 98.11%Cor e Forma:SolidPeso molecular:540.68Simmiparib
CAS:<p>Simmiparib (SMOCL-9112) is a PARP1 and PARP2 inhibitor that promotes apoptosis.Simmiparib is used to study Parkinson's disease and melanoma.</p>Fórmula:C23H18F4N6O2Pureza:99.05% - 99.51%Cor e Forma:SolidPeso molecular:486.42Sparfosic Acid
CAS:<p>Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma</p>Fórmula:C6H10NO8PPureza:98.89%Cor e Forma:SolidPeso molecular:255.12ICG-001
CAS:<p>ICG001 is a β-catenin/TCF-mediated transcription inhibitor that selectively blocks β-catenin/CBP interaction.Cost-effective and quality-assured.</p>Fórmula:C33H32N4O4Pureza:99.55% - 99.62%Cor e Forma:SolidPeso molecular:548.63CCCI-01
CAS:<p>CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.</p>Fórmula:C11H9N3O4Pureza:>99.99%Cor e Forma:SolidPeso molecular:247.21SCAL-266
CAS:<p>SCAL-266, a potent inhibitor of mitochondrial complex I (CI), exhibits an IC50 of 0.83 μM.</p>Fórmula:C27H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:511.54MIR96-IN-1
CAS:<p>MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.</p>Fórmula:C33H48N8O2Cor e Forma:SolidPeso molecular:588.79BP-1-108
CAS:<p>BP-1-108 is a potent and selective STAT5 inhibitor.</p>Fórmula:C32H38N2O6SCor e Forma:SolidPeso molecular:578.72RC-33 HCl
CAS:<p>RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.</p>Fórmula:C21H28ClNPureza:98%Cor e Forma:SolidPeso molecular:329.91SMBA2
CAS:<p>SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.</p>Fórmula:C8H16N4Pureza:98%Cor e Forma:SolidPeso molecular:168.24Gea 3162
CAS:<p>GEA 3162 blocks ADP-induced platelet clumping in PRP and boosts cGMP in granulocytes and leukocytes.</p>Fórmula:C7H4Cl2N4OPureza:98%Cor e Forma:SolidPeso molecular:231.04TL02-59 dihydrochloride
CAS:<p>TL02-59 dihydrochloride is an orally active inhibitor of Src-family kinase Fgr (IC50: 0.03 nM).</p>Fórmula:C32H36Cl2F3N5O4Pureza:98%Cor e Forma:SolidPeso molecular:682.56Apoptosis inducer 6
CAS:<p>Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.</p>Fórmula:C27H26N4O3SCor e Forma:SolidPeso molecular:486.59MEB55
CAS:<p>MEB55, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.</p>Fórmula:C22H17NO4SPureza:98%Cor e Forma:SolidPeso molecular:391.44CAY10747
CAS:<p>CAY10747, a celastrol derivative, inhibits Hsp90-Cdc37 interaction, decreases client proteins, and induces apoptosis in various cancer cells.</p>Fórmula:C42H48FNO6Cor e Forma:SolidPeso molecular:681.83c-Met-IN-9
CAS:<p>c-Met-IN-9 is a 4-phenoxypyridine derivative and a c-Met kinase inhibitor (IC50: 12 nM). c-Met-IN-9 induces apoptosis and shows antitumour effects.</p>Fórmula:C25H19F2N5O3Cor e Forma:SolidPeso molecular:475.45B-Raf IN 9
CAS:<p>B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).</p>Fórmula:C23H20N4OSCor e Forma:SolidPeso molecular:400.5PI3Kα-IN-7
CAS:<p>PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.</p>Fórmula:C17H22N8O2SCor e Forma:SolidPeso molecular:402.47PERK-IN-3
CAS:<p>PERK-IN-3 is a potent inhibitor of PERK(IC50 of 7.4 nM).</p>Fórmula:C22H16F2N4O2Pureza:98%Cor e Forma:SolidPeso molecular:406.38Bozepinib
CAS:<p>Bozepinib is an antitumor compound that acts by inducing PKR-mediated apoptosis and synergizing with IFN.</p>Fórmula:C20H14Cl2N6O5SPureza:98%Cor e Forma:SolidPeso molecular:521.33MCL-1/BCL-2-IN-3
CAS:<p>MCL-1/BCL-2-IN-3 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor with IC50s of 5.95 and 4.78 μM, respectiely.</p>Fórmula:C27H25BrN2O5SCor e Forma:SolidPeso molecular:569.47HMBPP triammonium
CAS:<p>HMBPP triammonium is a stimulator of gamma delta T cells.</p>Fórmula:C5H15NO8P2Cor e Forma:SolidPeso molecular:279.122CDK9-IN-18
CAS:<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Fórmula:C27H20N8OCor e Forma:SolidPeso molecular:472.5YH-306
CAS:<p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>Fórmula:C19H18N2O2Pureza:98.06%Cor e Forma:SolidPeso molecular:306.36GSK962
CAS:<p>GSK962 is a GSK963 inactive enantiomer. It can be used to confirm the on-target effects.</p>Fórmula:C14H18N2OPureza:99.75%Cor e Forma:SolidPeso molecular:230.31PARP1/BRD4-IN-1
CAS:<p>PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.</p>Fórmula:C29H26N6O3Cor e Forma:SolidPeso molecular:506.56hGGPPS-IN-1
CAS:<p>HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.</p>Fórmula:C13H13N3O6P2SCor e Forma:SolidPeso molecular:401.27MDM2-IN-1
CAS:<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Fórmula:C23H21Cl2FN2O3Cor e Forma:SolidPeso molecular:463.33Isodispar B
CAS:<p>Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.</p>Fórmula:C20H18O5Cor e Forma:SolidPeso molecular:338.35ASK1-IN-3
CAS:<p>ASK1-IN-3, selective ASK1 inhibitor with 33.8 nM IC50; inhibits cell cycle kinases; induces apoptosis in HepG2 cells.</p>Fórmula:C18H18N8O2Cor e Forma:SolidPeso molecular:378.39SZM-1209
CAS:<p>SZM-1209 is a potent and specific RIPK1 inhibitor with oral activity, displaying a dissociation constant (Kd) of 85 nM.</p>Fórmula:C31H29F5N4O5S2Pureza:98%Cor e Forma:SolidPeso molecular:696.71Ozarelix
CAS:<p>Ozarelix: a GnRH antagonist that induces apoptosis in advanced prostate cancer, modulates death receptors, and reduces sex hormones.</p>Fórmula:C72H96ClN17O14Cor e Forma:SolidPeso molecular:1459.09ZINC69391
CAS:<p>ZINC69391 inhibits Rac1, reduces cancer cell growth and metastasis, and induces apoptosis.</p>Fórmula:C14H14F3N5Pureza:99.61%Cor e Forma:SolidPeso molecular:309.29SAR125844
CAS:<p>SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)</p>Fórmula:C25H23FN8O2S2Pureza:98.73%Cor e Forma:SolidPeso molecular:550.63IST5-002
CAS:<p>IST5-002: Potent Stat5a/b blocker, IC50 1.5μM/3.5μM, targets prostate cancer & CML.</p>Fórmula:C17H20N5O7PPureza:99.36%Cor e Forma:SolidPeso molecular:437.34Dimethoate
CAS:<p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>Fórmula:C5H12NO3PS2Pureza:99.74% - 99.91%Cor e Forma:White Crystalline SolidPeso molecular:229.26Topoisomerase II inhibitor 11
CAS:<p>Topoisomerase II inhibitor 11 (compound 3d) is a potent inhibitor of Topoisomerase II (IC50: 2.89 μM).</p>Fórmula:C27H21BrCl2N2O2SCor e Forma:SolidPeso molecular:588.34Rhosin
CAS:<p>Rhosin is a specific inhibitor of RhoA GTPases (Kd: ~0.4 uM), blocking RhoA-GEF interaction, not affecting Cdc42/Rac1/LARG, and induces apoptosis.</p>Fórmula:C20H18N6OPureza:98%Cor e Forma:SolidPeso molecular:358.4GZD856
CAS:<p>GZD856 is an orally bioavailable PDGFRα/β inhibitor (IC50s: 68.6 and 136.6 nM) with anti-lung cancer activities.</p>Fórmula:C29H27F3N6OPureza:98%Cor e Forma:SolidPeso molecular:532.56VU 0364739 hydrochloride
CAS:<p>VU 0364739 hydrochloride (VU 0364739 HCl) is a phospholipase D2 (PLD2) inhibitor that induces apoptosis and can be used in cancer research.</p>Fórmula:C26H28ClFN4O2Pureza:99.36%Cor e Forma:SolidPeso molecular:482.98PARP-2-IN-3
CAS:<p>PARP-2-IN-3 is used in the study of breast cancer as a PARP-2 inhibitor with antitumor activity that induces apoptosis (apoptosis) and necrosis in cancer cells.</p>Fórmula:C20H20ClN3O3Pureza:99.33%Cor e Forma:SolidPeso molecular:385.84BN201
CAS:<p>BN201 (OCS-05) is a neuroprotective drug by activating SGK2 and FOXO3 pathway. BN201 is able to regulate multiple kinases in the IGF1 pathway and cross BBB.</p>Fórmula:C25H38FN5O4Pureza:99.42% - 99.42%Cor e Forma:SolidPeso molecular:491.6RLX
CAS:<p>RLX (PD 139530) is a PI3K/Akt/FoxO3a signal inhibitor with anticancer,antitussive and anti-asthmatic activity,colon cancer，toxicity toward A549 cells..</p>Fórmula:C13H14N2OPureza:99.81%Cor e Forma:SolidPeso molecular:214.26KS106
CAS:<p>KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.</p>Fórmula:C18H15BrF3N3O2SPureza:99.31%Cor e Forma:SolidPeso molecular:474.3PERK-IN-5
CAS:<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5HDAC8-IN-3
CAS:<p>HDAC8-IN-3 (P19) inhibits HDAC8 (IC50 9.3 μM), induces leukemic cell apoptosis, and enhances thermal stability.</p>Fórmula:C18H12N4O3S2Cor e Forma:SolidPeso molecular:396.44CAM 833
CAS:<p>CAM 833 inhibits BRCA2-RAD51 interaction; Kd for ChimRAD51 is 366 nM, disrupts RAD51 oligocoagulation, and induces apoptosis in G2/M cells.</p>Fórmula:C26H26ClFN4O5Pureza:99.83%Cor e Forma:SolidPeso molecular:528.96CTX1
CAS:<p>CTX1 is a small molecule activator of p53.</p>Fórmula:C14H10N4Pureza:98%Cor e Forma:SolidPeso molecular:234.26Arylquin 1
CAS:<p>Arylquin 1: a Par-4 secretagogue targeting vimentin; causes non-apoptotic cancer cell death via LMP.</p>Fórmula:C17H16FN3Cor e Forma:SolidPeso molecular:281.33MG-262
CAS:<p>MG-262 is a reversible proteasome inhibitor with multiple biological activities [1] [2] [3].</p>Fórmula:C25H42BN3O6Cor e Forma:SolidPeso molecular:491.43M199
CAS:<p>M199, a novel inhibitor of TLR3/9 activation, induces secretion of IL-6, IL-8 and TNFalpha in human PBMCs.</p>Fórmula:C17H17N3OPureza:98%Cor e Forma:SolidPeso molecular:279.34AMG-548
CAS:<p>AMG-548, oral p38α inhibitor (Ki=0.5 nM), >1000x selectivity over p38γ/δ, blocks TNFα (IC50=3 nM), also inhibits Wnt/Casein kinase 1δ/ε.</p>Fórmula:C29H27N5OPureza:99.91%Cor e Forma:SolidPeso molecular:461.56SMIP004
CAS:<p>SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.</p>Fórmula:C13H19NOPureza:99.86%Cor e Forma:SolidPeso molecular:205.3SD-36
CAS:<p>SD-36: Potent, selective PROTAC STAT3 degrader, Kd ~50 nM, effective on mutants, IC50=10 nM, strong anti-tumor effects, enables mouse tumor regression.</p>Fórmula:C59H62F2N9O12PPureza:98% - >99.99%Cor e Forma:SoildPeso molecular:1158.15SCH529074
CAS:<p>SCH529074 is a selective activator of p53 (Ki = 1 μM) and can be used in studies about non-small-cell lung carcinoma.</p>Fórmula:C31H36Cl2N6Pureza:99.57%Cor e Forma:SolidPeso molecular:563.56Mutant p53 modulator-1
CAS:<p>Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.</p>Fórmula:C27H32F4N8O2Cor e Forma:SolidPeso molecular:576.59PhiKan 083 hydrochloride
CAS:<p>PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).</p>Fórmula:C16H19ClN2Pureza:98%Cor e Forma:SolidPeso molecular:274.79CAY10506
CAS:<p>CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.</p>Fórmula:C20H26N2O4S3Cor e Forma:SolidPeso molecular:454.63PD-1/PD-L1-IN 5
CAS:<p>PD-1/PD-L1-IN 5 is a potent PD-1/PD-L1 protein/protein interaction inhibitor (IC50 ≤ 100 nM).</p>Fórmula:C22H18N4O3SCor e Forma:SolidPeso molecular:418.47Mitochonic Acid 35
CAS:<p>Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.</p>Fórmula:C19H19NO5Pureza:98%Cor e Forma:SolidPeso molecular:341.36Atopaxar
CAS:<p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Fórmula:C29H38FN3O5Pureza:97.07% - 98.07%Cor e Forma:SolidPeso molecular:527.63GL-331
CAS:<p>GL-331, a DNA topoisomerase II inhibitor, is used potentially for the treatment of small cell lung cancer and gastric cancer.</p>Fórmula:C27H24N2O9Cor e Forma:SolidPeso molecular:520.49Antitumor agent-83
<p>Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.</p>Fórmula:C29H30N6O2Cor e Forma:SolidPeso molecular:494.59PHA-690509
CAS:<p>PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.</p>Fórmula:C17H21N3O2SPureza:98%Cor e Forma:SolidPeso molecular:331.43Dipin
CAS:<p>Dipin is an Antineoplastic.</p>Fórmula:C12H24N6O2P2Pureza:98%Cor e Forma:SolidPeso molecular:346.31DC-5163
CAS:<p>DC-5163 inhibits GAPDH (IC50: 176.3 nM, Kd: 3.192 μM), targets cancer cell growth and glycolysis.</p>Fórmula:C18H20ClN3OSPureza:98%Cor e Forma:SolidPeso molecular:361.89PDE5-IN-3
CAS:<p>PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.</p>Fórmula:C21H14BrN5O2Cor e Forma:SolidPeso molecular:448.27Topoisomerase I inhibitor 2
CAS:<p>ZML-8 selectively inhibits Top1, blocks G2/M phase, causes DNA damage, and induces apoptosis with anti-tumor properties.</p>Fórmula:C18H15NO3Cor e Forma:SolidPeso molecular:293.32Prinomastat hydrochloride
CAS:<p>Prinomastat HCl, an oral MMP (1, 3, 9) inhibitor, IC50s: 79, 6.3, 5.0 nM, shows antitumor activity.</p>Fórmula:C18H22ClN3O5S2Pureza:98%Cor e Forma:SolidPeso molecular:459.97ARN 14494
CAS:<p>ARN 14494, a potent SPT inhibitor (IC50=27.3 nM), reduces ceramide synthesis and neuroinflammation, and protects against β-amyloid toxicity.</p>Fórmula:C24H32N4O3Cor e Forma:SolidPeso molecular:424.54PI3Kα-IN-6
CAS:<p>PI3Kα-IN-6 (Compound 5b) is a PI3Kα inhibitor that exhibits anticancer effects without toxicity to normal cells.</p>Fórmula:C16H15IN2OSCor e Forma:SolidPeso molecular:410.27Oxythiamine chloride HCl
CAS:<p>Oxythiamine chloride is a thiamine antagonist and anticancer agent that inhibits transketolase, affecting RNA/DNA synthesis and inducing apoptosis.</p>Fórmula:C12H17Cl2N3O2SCor e Forma:SolidPeso molecular:338.25iMAC2
CAS:<p>iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibiting</p>Fórmula:C19H20Br2FN3Cor e Forma:SolidPeso molecular:469.19Esuberaprost Sodium
CAS:<p>Famitinib (SHR1020), an oral drug, inhibits c-kit, VEGFR-2, and PDGFRβ (IC50: 2.3/4.7/6.6 nM) and triggers apoptosis in gastric cancer.</p>Fórmula:C23H27FN4O2Cor e Forma:SolidPeso molecular:410.48Vin-C01
CAS:<p>Vin-C01, a potent protector of pancreatic β-cells (EC50=0.22μM), aids in type 2 diabetes research by preventing STZ-induced β-cell apoptosis.</p>Fórmula:C20H24N2OCor e Forma:SolidPeso molecular:308.42Epofolate
CAS:<p>Epofolate: folate receptor-targeted antimitotic, delivers epothilone to cancer cells, inhibits mitosis, may halt tumor growth. Check clinical trials.</p>Fórmula:C67H92N16O22S3Cor e Forma:SolidPeso molecular:1569.74Gemcitabine monophosphate
CAS:<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Fórmula:C9H12F2N3O7PCor e Forma:SolidPeso molecular:343.18Xanthine oxidase-IN-6
<p>Xanthine oxidase-IN-6: potent oral mixed-type XOD inhibitor, IC50 1.37 µM, anti-hyperuricemia, renal protection.</p>Fórmula:C29H34N2O15Cor e Forma:SolidPeso molecular:650.58MMPSI
CAS:<p>MMPSI (Caspase-3/7 Inhibitor I) is a caspase 3 and caspase 7 inhibitor that inhibits ischemic injury in cardiomyocytes and can be used to study cardioprotection</p>Fórmula:C14H16N2O5SPureza:99.74%Cor e Forma:SolidPeso molecular:324.35IW-927
CAS:<p>IW-927 is a potent and selective TNFα/TNFRc1 interaction antagonist.</p>Fórmula:C22H23N3O3S2Cor e Forma:SolidPeso molecular:441.57SDZ 224-015
CAS:<p>SDZ 224-015 is an inhibitor of interleukin-1β (IL-1β) converting enzyme and caspase-1 with anti-COVID-19 and anti-inflammatory activity.</p>Fórmula:C30H35Cl2N3O9Pureza:95.49% - 95.49%Cor e Forma:SolidPeso molecular:652.52hnRNPK-IN-1
CAS:<p>hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.</p>Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43CDK1/Cyc B-IN-1
CAS:<p>CDK1/Cyc B-IN-1: Potent CDK1/Cyc B inhibitor, IC50 97 nM, induces apoptosis, arrests G2/M cycle, halts cancer growth.</p>Fórmula:C14H12ClN3O2S2Cor e Forma:SolidPeso molecular:353.85VEGFR-2/BRAF-IN-1
<p>VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.</p>Fórmula:C26H20Cl2F3N5O3S2Cor e Forma:SolidPeso molecular:642.5HJC0416
CAS:<p>HJC0416 is a potent orally bioavailable signal transducer and activator of transcription 3 inhibitor.</p>Fórmula:C18H17ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:392.86Apoptotic agent-1
CAS:<p>Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.</p>Fórmula:C12H6ClN5O2SCor e Forma:SolidPeso molecular:319.73PHM16
CAS:<p>PHM16 is an ATP competitive FAK and FGFR2 inhibitor.</p>Fórmula:C20H22N6O4Pureza:98%Cor e Forma:SolidPeso molecular:410.43VRT-043198
CAS:<p>VRT-043198, a VX-765 metabolite, is a potent ICE/caspase-1 inhibitor, crossing the blood-brain barrier with K i of 0.8/0.6 nM.</p>Fórmula:C22H29ClN4O6Cor e Forma:SolidPeso molecular:480.94LG190178
CAS:<p>LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.</p>Fórmula:C28H42O5Cor e Forma:SolidPeso molecular:458.63CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Fórmula:C14H15NO4Pureza:98%Cor e Forma:SolidPeso molecular:261.27DNL343
CAS:<p>DNL343 is an eIF2B activator that inhibits stress granule (SG) assembly induced by the C9ORF72 dipeptide repeat.</p>Fórmula:C20H19ClF3N3O4Pureza:99.96%Cor e Forma:SolidPeso molecular:457.83CMLD012072
CAS:<p>CMLD012072 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor with potent anti-neoplastic activity. It can induce RNA clamping of eIF4A1 and eIF4A2.</p>Fórmula:C32H32N2O7Pureza:98%Cor e Forma:SolidPeso molecular:556.61
