Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
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DNA topoisomerase II inhibitor 1
CAS:<p>Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.</p>Fórmula:C28H24N4O3SCor e Forma:SolidPeso molecular:496.58MDM2/XIAP-IN-3
CAS:<p>MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing</p>Fórmula:C29H30N2O5SCor e Forma:SolidPeso molecular:518.62EGFR/BRAFV600E-IN-1
CAS:<p>EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).</p>Fórmula:C24H24ClN3O3Cor e Forma:SolidPeso molecular:437.92YC-137
CAS:<p>YC-137 inhibits BCL-2, triggers apoptosis in Bcl-2-high cells, and blocks its anti-apoptotic function.</p>Fórmula:C24H21N3O6S2Cor e Forma:SolidPeso molecular:511.57Anticancer agent 50
CAS:<p>Anticancer agent 50 targets ABCB1 pump, has cytotoxic effects, alters cyclin D1/p53, and shows promise in T lymphoma research.</p>Fórmula:C30H32N2O4SeCor e Forma:SolidPeso molecular:563.55Sparfosic acid trisodium
CAS:<p>Sparfosic acid trisodium is a CAD (carbamoyl-phosphate synthetase 2) inhibitor and also an aspartate transcarbamoyl transferase inhibitor with antitumour</p>Fórmula:C6H9NNaO8PPureza:98%Cor e Forma:SolidPeso molecular:277.1IQDMA
CAS:<p>IQDMA is an inhibitor of the transcription factor STAT5.</p>Fórmula:C19H20N4Cor e Forma:SolidPeso molecular:304.39RET-IN-16
CAS:<p>RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.</p>Fórmula:C31H29F3N8O2Cor e Forma:SolidPeso molecular:602.61Lemuteporfin
CAS:<p>Lemuteporfin is a light-activated photosensitizing agent confers cytotoxic upon light activation.reduce sebaceous gland volume in animal studies.</p>Fórmula:C44H48N4O10Pureza:97.14% - 99.44%Cor e Forma:SolidPeso molecular:792.87MMPSI
CAS:<p>MMPSI (Caspase-3/7 Inhibitor I) is a caspase 3 and caspase 7 inhibitor that inhibits ischemic injury in cardiomyocytes and can be used to study cardioprotection</p>Fórmula:C14H16N2O5SPureza:99.74%Cor e Forma:SolidPeso molecular:324.35SEC
CAS:<p>SEC triggers ANXA7 GTPase via AMPK/mTORC1/STAT3, causing ITGB4-driven apoptosis in ITGB4-high cancer cells.</p>Fórmula:C22H23ClN2O5Cor e Forma:SolidPeso molecular:430.88FD223
CAS:<p>FD223, a PI3Kδ inhibitor, is highly potent (IC50=1 nM) and selective, limiting AML cell growth by causing G1 arrest.</p>Fórmula:C17H12ClN5O2SCor e Forma:SolidPeso molecular:385.83CAY10773
CAS:<p>CAY10773, a sorafenib derivative, inhibits cancer cells over non-cancerous ones and induces apoptosis or ferroptosis in T24 cells.</p>Fórmula:C22H17Cl2N5OCor e Forma:SolidPeso molecular:438.31TNF-α-IN-18
CAS:<p>TNF-α-IN-18 is a small molecule TNF-α inhibitor that blocks NF-κB translocation, alleviates sepsis in models, and protects against rheumatoid arthritis in mice.</p>Fórmula:C16H7ClF2O4Pureza:99.77%Cor e Forma:SolidPeso molecular:336.67Tubulin polymerization-IN-31
CAS:<p>Compound 4c, inhibits tubulin polymerization, IC50 3.64 μM, and induces cancer cell apoptosis.</p>Fórmula:C18H13ClFN3Cor e Forma:SolidPeso molecular:325.77STAT3-IN-11
CAS:<p>STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.</p>Fórmula:C20H17NO4Pureza:98.3%Cor e Forma:SolidPeso molecular:335.35WJ35435
CAS:<p>WJ35435 is a histone deacetylase and topoisomerase I dual inhibitor.</p>Fórmula:C20H21N3O3Pureza:98%Cor e Forma:SolidPeso molecular:351.4Topoisomerase I inhibitor 3
CAS:<p>Topoisomerase I (Compound ZML-14) inhibitor 3 induces HepG2 cell apoptosis and arrests cell cycle at G2/M phase.</p>Fórmula:C18H14FNO3Cor e Forma:SolidPeso molecular:311.313-(3-Phenoxybenzyl)amino-β-carboline
CAS:<p>3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers.</p>Fórmula:C24H19N3OCor e Forma:SolidPeso molecular:365.43Bcl-2/Mcl-1-IN-1
CAS:<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Fórmula:C28H23NO3Cor e Forma:SolidPeso molecular:421.49CCCI-01
CAS:<p>CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.</p>Fórmula:C11H9N3O4Pureza:>99.99%Cor e Forma:SolidPeso molecular:247.21MI-389
CAS:<p>MI-389 is a PROTAC degrader that induces the degradation of receptor tyrosine kinases (RTKs), useful for leukemia research.</p>Fórmula:C35H35FN6O6Pureza:98.12%Cor e Forma:SolidPeso molecular:654.69VII-31
CAS:<p>VII-31 is an activator of the NEDDylation pathway, capable of inducing apoptosis in MCF-7, PC-3, and MGC-803 cells.</p>Fórmula:C23H25NO5SCor e Forma:SolidPeso molecular:427.51BRD0476
CAS:<p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.</p>Fórmula:C35H38N4O8SPureza:98%Cor e Forma:SolidPeso molecular:674.76AZD-5991 Racemate
CAS:<p>AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.</p>Fórmula:C35H34ClN5O3S2Cor e Forma:SolidPeso molecular:672.26PSB 0474
CAS:<p>P2Y6 receptor agonist</p>Fórmula:C17H20N2O13P2Pureza:98%Cor e Forma:SolidPeso molecular:522.29BP-1-108
CAS:<p>BP-1-108 is a potent and selective STAT5 inhibitor.</p>Fórmula:C32H38N2O6SCor e Forma:SolidPeso molecular:578.72Dimethoate
CAS:<p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>Fórmula:C5H12NO3PS2Pureza:99.74% - 99.91%Cor e Forma:White Crystalline SolidPeso molecular:229.26Apoptosis inducer 6
CAS:<p>Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.</p>Fórmula:C27H26N4O3SCor e Forma:SolidPeso molecular:486.59MMP-9-IN-3
CAS:<p>MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.</p>Fórmula:C29H25N3O4Cor e Forma:SolidPeso molecular:479.53B-Raf IN 9
CAS:<p>B-Raf IN 9 is a potent B-Raf inhibitor (IC50=24.79 nM), induces G2/M arrest and apoptosis, and inhibits PC-3 prostate cancer cells (IC50=7.83 μM).</p>Fórmula:C23H20N4OSCor e Forma:SolidPeso molecular:400.5MEB55
CAS:<p>MEB55, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.</p>Fórmula:C22H17NO4SPureza:98%Cor e Forma:SolidPeso molecular:391.44PI3Kα-IN-7
CAS:<p>PI3Kα-IN-7 (Compound A12) is a potent PI3Kα inhibitor, and also inhibits PI3Kβ.</p>Fórmula:C17H22N8O2SCor e Forma:SolidPeso molecular:402.47RIPK1-IN-11
CAS:<p>RIPK1-IN-11, an oral RIPK1 blocker, Kd 9.2 nM, IC50 67 nM, prevents necrosis and inflammation in cells.</p>Fórmula:C23H24N4O4SCor e Forma:SolidPeso molecular:452.53ZMF-10
CAS:<p>ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.</p>Fórmula:C19H17F6N7OCor e Forma:SolidPeso molecular:473.38Gea 3162
CAS:<p>GEA 3162 blocks ADP-induced platelet clumping in PRP and boosts cGMP in granulocytes and leukocytes.</p>Fórmula:C7H4Cl2N4OPureza:98%Cor e Forma:SolidPeso molecular:231.04αβ-Tubulin-IN-1
CAS:<p>αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.</p>Fórmula:C25H19N3O3Cor e Forma:SolidPeso molecular:409.44CPI-7c
CAS:<p>CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.</p>Fórmula:C22H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:358.39NSC-741909
CAS:<p>NSC-741909 is an anticancer agent that acts by suppressing the growth of several cell lines.</p>Fórmula:C16H14ClNOPureza:98%Cor e Forma:SolidPeso molecular:271.74RET-IN-15
CAS:<p>RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Fórmula:C27H28N8O2Cor e Forma:SolidPeso molecular:496.56STAT3-IN-10
CAS:<p>STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).</p>Fórmula:C17H13NO5Cor e Forma:SolidPeso molecular:311.29Bcl-2-IN-9
CAS:<p>Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.</p>Fórmula:C27H31N7O3SCor e Forma:SolidPeso molecular:533.65Anticancer agent 71
CAS:<p>Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.</p>Fórmula:C18H13ClF3N5OCor e Forma:SolidPeso molecular:407.78CA224
CAS:<p>CA224: selective oral Cdk4-cyclin D1 inhibitor, IC50=6.2μM, promotes apoptosis, has antitumor effects.</p>Fórmula:C24H22N2OCor e Forma:SolidPeso molecular:354.44Nevanimibe
CAS:<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Fórmula:C27H39N3OPureza:98%Cor e Forma:SolidPeso molecular:421.62(rel)-Oxaliplatin
CAS:<p>(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.</p>Fórmula:C8H14N2O4PtCor e Forma:SolidPeso molecular:397.29PARP1-IN-10
CAS:<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Fórmula:C20H23N3O5Cor e Forma:SolidPeso molecular:385.41AMPK activator 11
CAS:<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Fórmula:C25H20N4O2Pureza:98%Cor e Forma:SolidPeso molecular:408.45CCT373566
CAS:<p>CCT373566: potent BCL6 degrader, oral, IC50 2.2 nM; hinders cell growth in vitro & shrinks tumors in vivo.</p>Fórmula:C26H29ClF2N6O3Cor e Forma:SolidPeso molecular:547YM-155 hydrochloride
CAS:<p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>Fórmula:C20H19ClN4O3Cor e Forma:SolidPeso molecular:398.85CFM 4
CAS:CFM 4 is a potent small molecule CARP-1/APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosisFórmula:C22H16ClN3OSPureza:98.16%Cor e Forma:SolidPeso molecular:405.9Apoptotic agent-3
CAS:<p>"Apoptotic agent-3 targets Bcl-2/Bax, activates caspase-3, and has anti-proliferative properties for cancer research."</p>Fórmula:C31H21N5OSCor e Forma:SolidPeso molecular:511.6MeOIstPyrd
CAS:<p>MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsic</p>Fórmula:C14H16N4O2SCor e Forma:SolidPeso molecular:304.37MK-886 sodium salt
CAS:<p>MK-886 sodium salt inhibits leukotriene biosynthesis in leukocytes.</p>Fórmula:C27H33ClNNaO2SCor e Forma:SolidPeso molecular:494.06QTX125
CAS:<p>QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.</p>Fórmula:C23H19N3O5Cor e Forma:SolidPeso molecular:417.41Topoisomerase II inhibitor 7
CAS:<p>Topoisomerase II inhibitor 7 halts cell division and induces apoptosis, targeting topoisomerase II alpha with a 3.19 μM IC50.</p>Fórmula:C32H28BrN5O5SCor e Forma:SolidPeso molecular:674.56PARP-2-IN-3
CAS:<p>PARP-2-IN-3 is used in the study of breast cancer as a PARP-2 inhibitor with antitumor activity that induces apoptosis (apoptosis) and necrosis in cancer cells.</p>Fórmula:C20H20ClN3O3Pureza:99.33%Cor e Forma:SolidPeso molecular:385.84VO-OHPic
CAS:<p>VO-OHPic, a selective PTEN inhibitor (IC50 = 46 nM), reduces apoptosis and inflammation in doxorubicin-induced cardiomyopathy.</p>Fórmula:C12H10N2O8VCor e Forma:SolidPeso molecular:361.16ATX inhibitor 13
CAS:<p>ATX inhibitor 13: orally active, IC50 3.4 nM, halts RAW264.7 cells at G2, curbs growth/migration, prompts apoptosis, suppresses tumors.</p>Fórmula:C31H35Cl2N5O3Cor e Forma:SolidPeso molecular:596.55PD173952
CAS:<p>PD173952 is a Src kinase and Myt1 inhibitor with antitumor activity, inhibits Lyn, Abl and Csk, and induces Bcr-Abl-dependent hematopoietic cell apoptosis.</p>Fórmula:C24H21Cl2N5O2Pureza:99.5%Cor e Forma:SolidPeso molecular:482.36Berubicin HCl
CAS:<p>Berubicin hydrochloride, a brain-penetrating anthracycline, disrupts DNA replication and repair by inhibiting topoisomerase II.</p>Fórmula:C34H36ClNO11Cor e Forma:SolidPeso molecular:670.1Mcl-1 inhibitor 10
CAS:<p>Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 μM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers.</p>Fórmula:C21H15F3O4Cor e Forma:SolidPeso molecular:388.34PI3K inhibitor C 96
CAS:<p>PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myeloma in vitro and in vivo.</p>Fórmula:C11H8N2O3SPureza:98%Cor e Forma:SolidPeso molecular:248.26Erbstatin
CAS:<p>Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.</p>Fórmula:C9H9NO3Cor e Forma:SolidPeso molecular:179.17BI-0282
CAS:<p>BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.</p>Fórmula:C30H23Cl2FN4O4Cor e Forma:SolidPeso molecular:593.43PI3K/Akt/mTOR-IN-3
CAS:<p>PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.</p>Fórmula:C34H51NO2Cor e Forma:SolidPeso molecular:505.77Necrostatin-7
CAS:<p>Necrostatin-7 (Necrostatin 7) is a necrotic apoptosis inhibitor with cardioprotective effects that inhibits RANK-NFATc1 signaling.</p>Fórmula:C16H10FN5OS2Pureza:98.71%Cor e Forma:SolidPeso molecular:371.41Anti-inflammatory agent 22
CAS:<p>Compound 14a is an oral anti-inflammatory with an IC50 of 14.6 μM for TNF-α, preventing adipogenesis and reducing mouse limb lymphedema.</p>Fórmula:C22H16O6Cor e Forma:SolidPeso molecular:376.36Mitoguazone
CAS:<p>Mitoguazone is an antitumor agent, blocking SAM decarboxylase, disrupting polyamine synthesis, and hindering HIV DNA integration in immune cells.</p>Fórmula:C5H12N8Pureza:97.47% - 98%Cor e Forma:SolidPeso molecular:184.2Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Fórmula:C32H40BrN3O2Pureza:98%Cor e Forma:SolidPeso molecular:578.58Caylin-2
CAS:<p>Nutlin-3 activates p53 by blocking MDM2. Caylin-2, a nutlin-3 analog with trifluoromethyl instead of chlorine, is 10x less potent with an 8 μM IC50.</p>Fórmula:C32H30F6N4O4Cor e Forma:SolidPeso molecular:648.6Apogossypolone (ApoG2)
CAS:<p>Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i</p>Fórmula:C28H26O8Cor e Forma:SolidPeso molecular:490.5ZT55
CAS:<p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>Fórmula:C17H16N2O3Cor e Forma:SolidPeso molecular:296.32DMH2
CAS:<p>DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.</p>Fórmula:C27H25N5O2Pureza:98%Cor e Forma:SolidPeso molecular:451.52Anticancer agent 42
CAS:<p>Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.</p>Fórmula:C19H16Cl2N2O3Cor e Forma:SolidPeso molecular:391.25PARP1/BRD4-IN-1
CAS:<p>PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.</p>Fórmula:C29H26N6O3Cor e Forma:SolidPeso molecular:506.56S-Gem
CAS:<p>S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.</p>Fórmula:C13H15F2N3O6S2Pureza:98%Cor e Forma:SolidPeso molecular:411.4CHMFL-ABL/KIT-155
CAS:<p>CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM).</p>Fórmula:C33H38F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:609.68IM-93
CAS:<p>IM-93 inhibits ferroptosis and NETosis with an IC< sub>50 of 0.45 μM for cell death inhibition [1].</p>Fórmula:C21H28N4O2Cor e Forma:SolidPeso molecular:368.47Antiproliferative agent-7
CAS:<p>Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.</p>Fórmula:C28H32N4OCor e Forma:SolidPeso molecular:440.58Nec-3a
CAS:<p>Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM.</p>Fórmula:C21H18F4N2O4Cor e Forma:SolidPeso molecular:438.37HBV-IN-23
CAS:<p>HBV-IN-23: HBV replication inhibitor, IC50 0.58μM, affects resistant strains, induces HepG2 apoptosis, anti-HCC.</p>Fórmula:C25H27N3O3SCor e Forma:SolidPeso molecular:449.57Butyrolactone I
CAS:<p>Butyrolactone I (Olomoucin) inhibits CDKs, blocks cdc2 kinases, and shows antitumor activity in lung and prostate cancers.</p>Fórmula:C24H24O7Pureza:98%Cor e Forma:SolidPeso molecular:424.44GK563
CAS:<p>GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.</p>Fórmula:C16H22O2Cor e Forma:SolidPeso molecular:246.34Mps1-IN-5
CAS:<p>Mps1-IN-5: oral Mps1 inhibitor with 29 nM IC50, induces apoptosis, G2/M arrest, and has anti-tumor properties.</p>Fórmula:C24H25N9Cor e Forma:SolidPeso molecular:439.52MPT0B002
CAS:<p>MPT0B002 is a microtubule inhibitor that acts by downregulating T315I mutant Bcr-Abl and inducing apoptosis of imatinib-resistant chronic myeloid leukemia cells</p>Fórmula:C19H19NO4Pureza:98%Cor e Forma:SolidPeso molecular:325.36ARP 101
CAS:<p>ARP 101 is a selective matrix metalloproteinase-2 (MMP-2) inhibitor with anticancer activity.</p>Fórmula:C20H26N2O5SPureza:98.26%Cor e Forma:SolidPeso molecular:406.5HIOC
CAS:<p>TrkB agonist; shields neurons & retinas; crosses blood-brain & retinal barriers.</p>Fórmula:C16H19N3O3Cor e Forma:SolidPeso molecular:301.34EGFR/HER2/TS-IN-1
CAS:<p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>Fórmula:C24H15N5O4S2Cor e Forma:SolidPeso molecular:501.54NSC 107512
CAS:<p>NSC 107512, a sangivamycin-like molecule, inhibits CDK9, curbing myeloma growth and triggering cell death.</p>Fórmula:C12H16N6O5Cor e Forma:SolidPeso molecular:324.29Infliximab
CAS:<p>Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.</p>Pureza:98% - 99.70%Cor e Forma:LiquidPeso molecular:149 kDacRIPGBM
CAS:<p>cRIPGBM induces apoptosis in GBM CSCs by targeting RIPK2, with an EC50 of 68 nM in GBM-1 cells.</p>Fórmula:C26H20FN2O2Pureza:98%Cor e Forma:SolidPeso molecular:411.45c-Fms-IN-12
CAS:<p>c-Fms-IN-12 inhibits FMS/c-KIT, triggers A549 cell apoptosis, and has potential as a multi-cancer therapy.</p>Fórmula:C30H32N6O6Cor e Forma:SolidPeso molecular:572.61Z-LEVD-FMK
CAS:<p>Z-LEVD-FMK is a caspase-4 inhibitor with anti-cancer activity, capable of eliminating LPS-induced GCLC protein degradation.</p>Fórmula:C31H45FN4O10Cor e Forma:SolidPeso molecular:652.71CFM-5
CAS:<p>CFM-5 has anticonvulsant activity and is used in epilepsy research.</p>Fórmula:C23H18BrN3OSPureza:98%Cor e Forma:SolidPeso molecular:464.38Quinidine Monosulfate
CAS:<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Fórmula:C40H50N4O8SCor e Forma:SolidPeso molecular:746.92CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Fórmula:C15H18ClNO3Cor e Forma:SolidPeso molecular:295.76Targapremir-210
CAS:<p>Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.</p>Fórmula:C32H36N10O2Pureza:98%Cor e Forma:SolidPeso molecular:592.69MBC-11
CAS:<p>MBC-11: First bone-targeting bisphosphonate-etidronate conjugate with araC, may treat TIBD.</p>Fórmula:C11H20N3O14P3Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:511.21NBI-42902
CAS:<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Fórmula:C27H24F3N3O3Cor e Forma:SolidPeso molecular:495.49
