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Apoptose

Apoptose

Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.

Subcategorias de "Apoptose"

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Foram encontrados 5593 produtos de "Apoptose"

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  • NM-3

    CAS:
    <p>NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.</p>
    Fórmula:C13H12O6
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:264.23
  • EGFR-IN-11

    CAS:
    <p>EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.</p>
    Fórmula:C29H35N9O2S
    Pureza:99.93%
    Cor e Forma:Solid
    Peso molecular:573.71
  • UK-101

    CAS:
    <p>UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM</p>
    Fórmula:C25H48N2O5Si
    Pureza:99.08% - 99.25%
    Cor e Forma:Solid
    Peso molecular:484.74
  • LQZ-7F

    CAS:
    <p>LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.</p>
    Fórmula:C14H7N9O3
    Pureza:98.64%
    Cor e Forma:Solid
    Peso molecular:349.26
  • Necrostatin-5

    CAS:
    <p>Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.</p>
    Fórmula:C19H17N3O2S2
    Pureza:98.03%
    Cor e Forma:Solid
    Peso molecular:383.49
  • Ro 90-7501

    CAS:
    <p>Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.</p>
    Fórmula:C20H16N6
    Pureza:97.21% - 99.72%
    Cor e Forma:Solid
    Peso molecular:340.38
  • GS-9191

    CAS:
    <p>GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which</p>
    Fórmula:C37H51N8O6P
    Pureza:98.01 - 99.28%
    Cor e Forma:Solid
    Peso molecular:734.82
  • Alethine

    CAS:
    <p>Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.</p>
    Fórmula:C10H22N4O2S2
    Pureza:98.83%
    Cor e Forma:Solid
    Peso molecular:294.44
  • p53-MDM2-IN-1

    CAS:
    <p>p53-MDM2-IN-1 (Example 30), an inhibitor targeting the p53-MDM2/X protein interaction, exhibits a K i value of 23.35 µM.</p>
    Fórmula:C23H20ClN3O3
    Pureza:99.98%
    Cor e Forma:Soild
    Peso molecular:421.88
  • iCRT-5

    CAS:
    <p>iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity and can be used in the study of multiple myeloma.</p>
    Fórmula:C16H17NO5S2
    Pureza:99.68%
    Cor e Forma:Solid
    Peso molecular:367.44
  • Droloxifene

    CAS:
    <p>Droloxifene, a tamoxifen derivative and oral SERM, induces p53 and apoptosis; Fluroxifene protects bone, blocks estrogen and implantation.</p>
    Fórmula:C26H29NO2
    Pureza:99.86% - 99.97%
    Cor e Forma:Solid Powder
    Peso molecular:387.51
  • STAT3-IN-13

    CAS:
    <p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>
    Fórmula:C21H20N6O3S
    Pureza:98.89%
    Cor e Forma:Solid
    Peso molecular:436.49
  • AMG PERK 44

    CAS:
    <p>AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.</p>
    Fórmula:C34H29ClN4O2
    Pureza:98.8% - 99.81%
    Cor e Forma:Solid
    Peso molecular:561.07
  • HTH-01-091

    CAS:
    <p>HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,</p>
    Fórmula:C26H28Cl2N4O2
    Pureza:98.4%
    Cor e Forma:Solid
    Peso molecular:499.43
  • R306465

    CAS:
    <p>R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.</p>
    Fórmula:C19H19N5O4S
    Pureza:98.46% - 99.54%
    Cor e Forma:Solid
    Peso molecular:413.45
  • Mepazine

    CAS:
    <p>Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.</p>
    Fórmula:C19H22N2S
    Pureza:99.88% - 99.92%
    Cor e Forma:Solid
    Peso molecular:310.46
  • Tubulin inhibitor 11

    CAS:
    <p>Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.</p>
    Fórmula:C22H23N3O3S
    Pureza:98.32%
    Cor e Forma:Soild
    Peso molecular:409.5
  • MBM-55

    CAS:
    <p>MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.</p>
    Fórmula:C28H27FN6O2
    Pureza:99.83%
    Cor e Forma:Solid
    Peso molecular:498.55
  • LDCA

    CAS:
    <p>LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.</p>
    Fórmula:C8H5Cl3FNO
    Pureza:98.99%
    Cor e Forma:Solid
    Peso molecular:256.49
  • NSC49652

    CAS:
    <p>NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.</p>
    Fórmula:C14H11NO2
    Pureza:98.98%
    Cor e Forma:Solid
    Peso molecular:225.24
  • SCFSkp2-IN-2

    CAS:
    <p>SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.</p>
    Fórmula:C17H20N4O2
    Pureza:99.86%
    Cor e Forma:Solid
    Peso molecular:312.37
  • UCB-5307

    CAS:
    <p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>
    Fórmula:C22H21N3O
    Pureza:98.76%
    Cor e Forma:Solid
    Peso molecular:343.42
  • AQ4

    CAS:
    <p>AQ4 is a topoisomerase II inhibitor and DNA-inserting agent that inhibits proliferation and induces apoptosis in two cell lines.</p>
    Fórmula:C22H28N4O4
    Pureza:96.28% - 97.15%
    Cor e Forma:Solid
    Peso molecular:412.48
  • Gallium maltolate

    CAS:
    <p>Gallium maltolate is a ribonucleoside-diphosphate reductase inhibitor.</p>
    Fórmula:C18H15GaO9
    Pureza:99.61% - 99.67%
    Cor e Forma:Solid
    Peso molecular:445.03
  • RIPK3-IN-1

    CAS:
    <p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>
    Fórmula:C29H25FN4O4
    Pureza:98.27%
    Cor e Forma:Solid
    Peso molecular:512.53
  • Minodronic acid

    CAS:
    Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.
    Fórmula:C9H12N2O7P2
    Pureza:98.02%
    Cor e Forma:Solid
    Peso molecular:322.15
  • Sarmustine

    CAS:
    <p>SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.</p>
    Fórmula:C6H11ClN4O3
    Pureza:98.29% - 99.71%
    Cor e Forma:Solid
    Peso molecular:222.63
  • UC-112

    CAS:
    <p>UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).</p>
    Fórmula:C22H24N2O2
    Pureza:99.54%
    Cor e Forma:Solid
    Peso molecular:348.44
  • Apostatin-1

    CAS:
    <p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>
    Fórmula:C19H27N3OS
    Pureza:99.31%
    Cor e Forma:Solid
    Peso molecular:345.5
  • AOH1160

    CAS:
    <p>AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA).</p>
    Fórmula:C25H20N2O3
    Pureza:98.46% - 99.52%
    Cor e Forma:Solid
    Peso molecular:396.44
  • Dasatinib hydrochloride

    CAS:
    <p>Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).</p>
    Fórmula:C22H27Cl2N7O2S
    Pureza:99.88% - 99.98%
    Cor e Forma:Solid
    Peso molecular:524.47
  • XX-650-23

    CAS:
    <p>XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).</p>
    Fórmula:C18H12N2O2
    Pureza:97.01%
    Cor e Forma:Solid
    Peso molecular:288.3
  • CSN5i-3

    CAS:
    <p>CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5, as an anticancer agent.Cost-effective and quality-assured.</p>
    Fórmula:C28H29F2N5O2
    Pureza:99.56% - >99.99%
    Cor e Forma:Solid
    Peso molecular:505.56
  • FA16


    <p>FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16</p>
    Fórmula:C22H27F3N4O2S
    Pureza:99.44%
    Cor e Forma:Solid
    Peso molecular:468.54
  • P505-15 Acetate

    CAS:
    <p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>
    Fórmula:C21H27N9O3
    Pureza:99.99%
    Cor e Forma:Solid
    Peso molecular:453.5
  • RO-5963

    CAS:
    <p>RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).</p>
    Fórmula:C24H21ClF2N4O5
    Pureza:99.28%
    Cor e Forma:Solid
    Peso molecular:518.9
  • Vamotinib

    CAS:
    <p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>
    Fórmula:C29H27F3N6O
    Pureza:99.64%
    Cor e Forma:Solid
    Peso molecular:532.56
  • RS1-PDK1 inhibitor

    CAS:
    <p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>
    Fórmula:C15H9ClN2O2S3
    Pureza:98.12%
    Cor e Forma:Solid
    Peso molecular:380.89
  • K-8012

    CAS:
    <p>K-8012 is a modulator of the N-terminally truncated RXRα and improves anticancer activities in an RXRα-dependent manner.</p>
    Fórmula:C23H23FN4
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:374.45
  • DCG066

    CAS:
    <p>DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.</p>
    Fórmula:C30H31F6N3O2
    Pureza:98.26% - 98.38%
    Cor e Forma:Solid
    Peso molecular:579.58
  • GCN2-IN-1

    CAS:
    <p>GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.</p>
    Fórmula:C19H18N10O
    Pureza:99.49% - 99.64%
    Cor e Forma:Solid
    Peso molecular:402.41
  • Triparanol

    CAS:
    <p>Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1</p>
    Fórmula:C27H32ClNO2
    Pureza:99.72%
    Cor e Forma:Solid
    Peso molecular:438
  • Mitazalimab

    CAS:
    <p>Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.</p>
    Pureza:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)
    Cor e Forma:Liquid
  • OR-1896

    CAS:
    <p>OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.</p>
    Fórmula:C13H15N3O2
    Pureza:99.33%
    Cor e Forma:Solid
    Peso molecular:245.28
  • CUDC-427

    CAS:
    <p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>
    Fórmula:C29H36N6O4S
    Pureza:99.92%
    Cor e Forma:Solid
    Peso molecular:564.7
  • F16

    CAS:
    <p>F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.</p>
    Fórmula:C16H15IN2
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:362.21
  • Etomoxir

    CAS:
    <p>Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!</p>
    Fórmula:C17H23ClO4
    Pureza:98% - 99.39%
    Cor e Forma:Solid
    Peso molecular:326.82
  • CMLD-2

    CAS:
    <p>CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.</p>
    Fórmula:C31H31NO6
    Pureza:99.99%
    Cor e Forma:Solid
    Peso molecular:513.58
  • NLRP3/AIM2-IN-3

    CAS:
    <p>NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.</p>
    Fórmula:C16H14N2O2
    Pureza:97.04%
    Cor e Forma:Solid
    Peso molecular:266.29
  • Lanperisone HCl

    CAS:
    <p>Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.</p>
    Fórmula:C15H19ClF3NO
    Pureza:98.67% - >99.99%
    Cor e Forma:Solid
    Peso molecular:321.77
  • PARP/PI3K-IN-1

    CAS:
    <p>PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.</p>
    Fórmula:C33H28F4N8O3
    Pureza:99.59%
    Cor e Forma:Solid
    Peso molecular:660.62
  • Cot inhibitor-1

    CAS:
    <p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>
    Fórmula:C27H27Cl2FN8
    Pureza:98.59%
    Cor e Forma:Solid
    Peso molecular:553.46
  • cRIPGBM chloride

    CAS:
    <p>cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.</p>
    Fórmula:C26H20ClFN2O2
    Pureza:99.75%
    Cor e Forma:Solid
    Peso molecular:446.9
  • VAS 3947

    CAS:
    <p>VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.</p>
    Fórmula:C14H10N6OS
    Pureza:98.44%
    Cor e Forma:Solid
    Peso molecular:310.33
  • Tubulin inhibitor 32

    CAS:
    <p>Tubulin inhibitor 32 is a microtubule inhibitor with antiproliferative and antitumor activity that induces apoptosis and cell cycle arrest in the G2/M phase.</p>
    Fórmula:C18H19N3O3
    Pureza:99.92%
    Cor e Forma:Solid
    Peso molecular:325.36
  • Ro 08-2750

    CAS:
    <p>Ro 08-2750: A non-peptide NGF inhibitor binding NGF (~1 µM IC50) &amp; selectively inhibits p75NTR over TRKA and MSI RNA-binding (2.7 µM IC50).</p>
    Fórmula:C13H10N4O3
    Pureza:98.795%
    Cor e Forma:Solid
    Peso molecular:270.24
  • Prinomastat

    CAS:
    <p>Prinomastat: orally active, crosses blood-brain barrier, inhibits MMP-1/2/3/9, Ki/IC50s: 0.05-0.3/5.0-79 nM, antitumor.</p>
    Fórmula:C18H21N3O5S2
    Pureza:99.23%
    Cor e Forma:Solid
    Peso molecular:423.51
  • C6 Ceramide

    CAS:
    <p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>
    Fórmula:C24H47NO3
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:397.63
  • SYM 2081

    CAS:
    <p>SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.</p>
    Fórmula:C6H11NO4
    Pureza:99.59%
    Cor e Forma:Solid
    Peso molecular:161.16
  • TL4-12

    CAS:
    <p>TL4-12 is a MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation in vitro.</p>
    Fórmula:C25H27F3N6O2
    Pureza:98.38%
    Cor e Forma:Solid
    Peso molecular:500.52
  • N6-Cyclopentyladenosine

    CAS:
    <p>N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of</p>
    Fórmula:C15H21N5O4
    Pureza:99.84%
    Cor e Forma:Solid
    Peso molecular:335.36
  • Epristeride

    CAS:
    <p>Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.</p>
    Fórmula:C25H37NO3
    Pureza:98.12% - >99.99%
    Cor e Forma:Solid
    Peso molecular:399.57
  • Bomedemstat ditosylate

    CAS:
    <p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>
    Fórmula:C42H50FN7O8S2
    Pureza:99.05%
    Cor e Forma:Solid
    Peso molecular:864.02
  • Imipramine

    CAS:
    <p>Imipramine (Dimipressin) is a Fascin1 inhibitor with antitumor activity and induces apoptosis.</p>
    Fórmula:C19H24N2
    Pureza:99.4%
    Cor e Forma:White To Off-White /Hydrochloride/ Solid
    Peso molecular:280.41
  • DX3-213B

    CAS:
    <p>DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.</p>
    Fórmula:C20H28F2N2O5S2
    Pureza:99.85%
    Cor e Forma:Solid
    Peso molecular:478.57
  • HBED

    CAS:
    <p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>
    Fórmula:C20H24N2O6
    Pureza:97.35% - 98.58%
    Cor e Forma:Solid
    Peso molecular:388.41
  • BCL6-IN-7

    CAS:
    <p>BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.</p>
    Fórmula:C18H15ClN6O
    Pureza:99.03%
    Cor e Forma:Solid
    Peso molecular:366.8
  • SB 699551 dihydrochloride

    CAS:
    <p>SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.</p>
    Fórmula:C34H47Cl2N3O
    Pureza:99.83%
    Cor e Forma:Solid
    Peso molecular:584.66
  • SLMP53-1

    CAS:
    <p>SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migration</p>
    Fórmula:C20H18N2O2
    Pureza:99.64%
    Cor e Forma:Solid
    Peso molecular:318.37
  • Brigimadlin

    CAS:
    <p>Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.</p>
    Fórmula:C31H25Cl2FN4O3
    Pureza:98.17%
    Cor e Forma:Solid
    Peso molecular:591.46
  • MJN68390

    CAS:
    <p>MJN68390 has an apparent IC50 value of 15 μM against CASP8 and shows no activity against CASP10.</p>
    Fórmula:C24H28ClN3O3
    Pureza:98.86%
    Cor e Forma:Solid
    Peso molecular:441.95
  • TNIK-IN-3

    CAS:
    <p>TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK).</p>
    Fórmula:C23H18FN3O2
    Pureza:98.39%
    Cor e Forma:Solid
    Peso molecular:387.41
  • GSK2593074A

    CAS:
    <p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>
    Fórmula:C27H23N5OS
    Pureza:99.76%
    Cor e Forma:Solid
    Peso molecular:465.57
  • Deferitazole

    CAS:
    <p>Deferitazole (FBS 0701) is a novel and orally active, selective and high affinity iron chelator.</p>
    Fórmula:C18H25NO7S
    Pureza:99.48%
    Cor e Forma:Solid
    Peso molecular:399.46
  • Antifolate C2

    CAS:
    <p>Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.</p>
    Fórmula:C19H21N5O6S
    Pureza:99.57%
    Cor e Forma:Solid
    Peso molecular:447.46
  • UNC0321

    CAS:
    <p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>
    Fórmula:C27H45N7O3
    Pureza:99.80%
    Cor e Forma:Solid
    Peso molecular:515.69
  • RET-IN-23

    CAS:
    <p>RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.</p>
    Fórmula:C28H28FN11
    Pureza:97.46%
    Cor e Forma:Solid
    Peso molecular:537.59
  • DK419

    CAS:
    <p>DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.</p>
    Fórmula:C16H8ClF6N3O
    Pureza:99.63%
    Cor e Forma:Solid
    Peso molecular:407.7
  • Tiomolibdate diammonium

    CAS:
    <p>Tiomolibdate diammonium (NSC-286644) blocks SOD1 and COX, acting as an antiangiogenic and antitumor agent.</p>
    Fórmula:H8MoN2S4
    Pureza:98%
    Cor e Forma:Brown To Black Iridescent Crystalline Powder
    Peso molecular:260.28
  • H2L5186303

    CAS:
    <p>H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.</p>
    Fórmula:C26H20N2O8
    Pureza:98.19%
    Cor e Forma:Solid
    Peso molecular:488.45
  • TAI-1

    CAS:
    <p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>
    Fórmula:C24H21N3O3S
    Pureza:99.58%
    Cor e Forma:Solid
    Peso molecular:431.51
  • D609

    CAS:
    <p>D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.</p>
    Fórmula:C11H15KOS2
    Pureza:97.67% - 99.56%
    Cor e Forma:Off-White Powder
    Peso molecular:266.46
  • EM-12

    CAS:
    <p>EM-12, a Thalidomide analogue, is more active, stable, and boosts rat colon cancer studies.</p>
    Fórmula:C13H12N2O3
    Pureza:99.34%
    Cor e Forma:Solid
    Peso molecular:244.25
  • Ro24-7429

    CAS:
    <p>Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.</p>
    Fórmula:C14H13ClN4
    Pureza:99.29% - 99.85%
    Cor e Forma:Solid
    Peso molecular:272.73
  • CBS9106

    CAS:
    <p>CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.</p>
    Fórmula:C18H21ClF3N3O3
    Pureza:98.98%
    Cor e Forma:Solid
    Peso molecular:419.83
  • GSK854

    CAS:
    <p>GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.</p>
    Fórmula:C18H19ClN6O4S2
    Pureza:98.79%
    Cor e Forma:Solid
    Peso molecular:482.96
  • TC-DAPK 6

    CAS:
    <p>TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.</p>
    Fórmula:C17H12N2O2
    Pureza:98.73%
    Cor e Forma:Solid
    Peso molecular:276.29
  • eIF4A3-IN-1

    CAS:
    <p>eIF4A3-IN-1 is an inhibitor of eukaryotic initiation factor 4A3 (eIF4A3). eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.</p>
    Fórmula:C29H23BrClN5O2
    Pureza:99.49% - 99.89%
    Cor e Forma:Solid
    Peso molecular:588.88
  • EB1

    CAS:
    <p>EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits eIF4E phosphorylation.</p>
    Fórmula:C18H14N4
    Pureza:99.82%
    Cor e Forma:Solid
    Peso molecular:286.33
  • 1G244

    CAS:
    <p>1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.</p>
    Fórmula:C29H30F2N4O2
    Pureza:99.14%
    Cor e Forma:Solid
    Peso molecular:504.57
  • Sabizabulin

    CAS:
    <p>Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.</p>
    Fórmula:C21H19N3O4
    Pureza:98.10% - 99.79%
    Cor e Forma:Solid
    Peso molecular:377.39
  • AZA1

    CAS:
    <p>AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42.</p>
    Fórmula:C22H20N6
    Pureza:99.75%
    Cor e Forma:Solid
    Peso molecular:368.43
  • BC 11 hydrobromide

    CAS:
    <p>The compound is a selective urokinase inhibitor (IC50 = 8.2 μM). It also inhibits clot lysis with no effect on clot formation.</p>
    Fórmula:C8H12BBrN2O2S
    Pureza:98.07%
    Cor e Forma:Solid
    Peso molecular:290.97
  • CDK9-IN-7

    CAS:
    <p>CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.</p>
    Fórmula:C29H37N7O2S
    Pureza:98.08%
    Cor e Forma:Solid
    Peso molecular:547.71
  • W146

    CAS:
    <p>W146 is an S1PR1 antagonist that induces a significant but transient decrease in blood lymphocytes in mice.</p>
    Fórmula:C16H27N2O4P
    Pureza:99.37%
    Cor e Forma:Solid
    Peso molecular:342.37
  • Exisulind

    CAS:
    <p>Exisulind (CP248) triggers apoptosis via PKG activation, shows antitumor effects, and inhibits growth in various rodent cancer models.</p>
    Fórmula:C20H17FO4S
    Pureza:97.94%
    Cor e Forma:Solid
    Peso molecular:372.41
  • Cipepofol

    CAS:
    <p>HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.</p>
    Fórmula:C14H20O
    Pureza:99.77%
    Cor e Forma:Solid
    Peso molecular:204.31
  • Perphenazine dihydrochloride

    CAS:
    <p>Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.</p>
    Fórmula:C21H28Cl3N3OS
    Pureza:99.67%
    Cor e Forma:Solid
    Peso molecular:476.89
  • SPD304 dihydrochloride

    CAS:
    <p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>
    Fórmula:C32H34Cl2F3N3O2
    Pureza:99.25%
    Cor e Forma:Solid
    Peso molecular:620.53
  • A09-003

    CAS:
    <p>A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.</p>
    Fórmula:C23H26N4O
    Pureza:99.61%
    Cor e Forma:Solid
    Peso molecular:374.48