Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(144 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(139 produtos)
- PDK(9 produtos)
- PERK(26 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6071 produtos de "Apoptose"
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RS1-PDK1 inhibitor
CAS:<p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>Fórmula:C15H9ClN2O2S3Pureza:98.12%Cor e Forma:SolidPeso molecular:380.89UC-112
CAS:UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).Fórmula:C22H24N2O2Pureza:99.54%Cor e Forma:SolidPeso molecular:348.44Ref: TM-T17195
1mg35,00€2mg47,00€5mg73,00€10mg104,00€25mg213,00€50mg329,00€100mg470,00€500mgA consultar1mL*10mM (DMSO)82,00€TAI-1
CAS:TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.Fórmula:C24H21N3O3SPureza:99.58%Cor e Forma:SolidPeso molecular:431.51UK-101
CAS:UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μMFórmula:C25H48N2O5SiPureza:98.97% - 99.08%Cor e Forma:SolidPeso molecular:484.74eIF4A3-IN-1
CAS:<p>eIF4A3-IN-1 is an inhibitor of eukaryotic initiation factor 4A3 (eIF4A3). eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.</p>Fórmula:C29H23BrClN5O2Pureza:99.49% - 99.89%Cor e Forma:SolidPeso molecular:588.88BCP-T.A
CAS:BCP-T.A is an iron death inducer that acts by binding to GPX4.Fórmula:C23H19Cl2N3OSPureza:99.49%Cor e Forma:SolidPeso molecular:456.39DX3-213B
CAS:DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.Fórmula:C20H28F2N2O5S2Pureza:99.85%Cor e Forma:SolidPeso molecular:478.57Ref: TM-T63136
1mg81,00€5mg170,00€10mg274,00€25mg588,00€50mg852,00€100mg1.159,00€1mL*10mM (DMSO)180,00€C6 Ceramide
CAS:<p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>Fórmula:C24H47NO3Pureza:99.67%Cor e Forma:SolidPeso molecular:397.63NM-3
CAS:NM-3, an oral anti-angiogenic and anti-tumor agent, modulates radiation and blocks VEGF to curb endothelial growth and induce apoptosis.Fórmula:C13H12O6Pureza:99.89%Cor e Forma:SolidPeso molecular:264.23Ref: TM-T33701
1mg180,00€5mg457,00€10mg652,00€25mg1.026,00€50mg1.406,00€100mg1.890,00€500mg3.725,00€1mL*10mM (DMSO)416,00€EGFR-IN-11
CAS:EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.Fórmula:C29H35N9O2SPureza:99.93%Cor e Forma:SolidPeso molecular:573.71Trk-IN-9
CAS:Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.Fórmula:C23H24ClFN6OPureza:98.15%Cor e Forma:SolidPeso molecular:454.93Lanperisone HCl
CAS:Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.Fórmula:C15H19ClF3NOPureza:98.67% - >99.99%Cor e Forma:SolidPeso molecular:321.77Necrostatin-5
CAS:Necrostatin-5 (Nec-5) inhibits RIP1 kinase, prevents cell necrosis, and protects Fadd-deficient Jurkat cells with an EC50 of 240 nM.Fórmula:C19H17N3O2S2Pureza:99.40%Cor e Forma:SolidPeso molecular:383.49Exisulind
CAS:Exisulind (CP248) triggers apoptosis via PKG activation, shows antitumor effects, and inhibits growth in various rodent cancer models.Fórmula:C20H17FO4SPureza:97.94%Cor e Forma:SolidPeso molecular:372.41BTM-3528
CAS:BTM-3528 is a mitochondrial protease OMA1 activator that induces an overactivation of the mitochondrial integrated stress response (ISR).Fórmula:C24H19F4N3O2S2Pureza:99.37% - 99.37%Cor e Forma:SolidPeso molecular:521.55CPT-Se4
CAS:CPT-Se4, a seleno-derivative of CPT, effectively kills cancer cells, triggers apoptosis, and is cytotoxic against various cell lines.Fórmula:C25H24N2O7Se2Pureza:98%Cor e Forma:SolidPeso molecular:622.39JMJD3/HDAC-IN-1
CAS:Compound A5b, also known as JMJD3/HDAC-IN-1, is a dual inhibitor that targets both JMJD3 (Jumonji domain-containing protein demethylase 3) and HADC1 (histoneFórmula:C21H30N6O2Pureza:98%Cor e Forma:SolidPeso molecular:398.5Antitumor agent-110
CAS:Antitumor Agent-110 (Compound 13), an imidazotetrazine anticancer agent, exhibits excellent permeability.Fórmula:C10H6N6OSPureza:98%Cor e Forma:SolidPeso molecular:258.26UNC3474
CAS:UNC3474, a small molecule ligand, selectively interacts with the aromatic methyl-lysine binding cage of the tumor protein 53BP1 Tudor domain (TT), exhibiting aFórmula:C17H28N2OCor e Forma:SolidPeso molecular:276.42RIPK1-IN-8
CAS:RIPK1-IN-8 is an aminoimidazolopyridine and is a selective and potent inhibitor of RIPK1 (IC50: 4 nM).RIPK1-IN-8 has research potential in inflammatory diseasesFórmula:C26H24F2N6O3Cor e Forma:SolidPeso molecular:506.5
