Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(143 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(139 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(89 produtos)
- c-RET(58 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5966 produtos de "Apoptose"
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TM5441 sodium
CAS:<p>TM5441, an orally bioavailable plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 values ranging from 13.9 to 51.1 μM, effectively induces intrinsic apoptosis across multiple human cancer cell lines. Additionally, it mitigates Nω-nitro-l-arginine methyl ester-induced cardiac hypertension and vascular senescence [1] [2].</p>Fórmula:C21H16ClN2NaO6Cor e Forma:SolidPeso molecular:450.8GDC-2394
CAS:GDC-2394: Oral, selective NLRP3 inhibitor; blocks IL-1β (human 0.4μM, mouse 0.1μM), spares NLRC4.Fórmula:C20H25N5O4SCor e Forma:SolidPeso molecular:431.51Bcl-2-IN-16
CAS:Bcl-2-IN-16 is a Bcl-2 (B-cell lymphoma 2) inhibitor [1].Fórmula:C53H63ClN8O10SCor e Forma:SolidPeso molecular:1039.63NF 023
CAS:NF 023 is a potent, selective P2X1 purinoceptor antagonist.Fórmula:C35H26N4O21S6Cor e Forma:SolidPeso molecular:1030.99Necrocide 1
CAS:Necrocide 1 is a inducer of cancer cell necrosis that is not inhibited by caspase, BCL2 , or TNFα, and acts through the mitochondrial regulatory pathway.Fórmula:C23H27NO3Pureza:98%Cor e Forma:SolidPeso molecular:365.47FHND5071
CAS:<p>FHND5071, a potent and selective RET kinase inhibitor, exerts antitumor effects through the inhibition of RET autophosphorylation and may be utilized for tumor</p>Fórmula:C30H30D3N9OCor e Forma:SolidPeso molecular:538.66MAO-B-IN-26
CAS:MAO-B-IN-26 (Compound IC9) serves as both a MAO-B and acetylcholinesterase inhibitor.Fórmula:C17H12BrNOPureza:98%Cor e Forma:SolidPeso molecular:326.19SD 1008
CAS:SD 1008 is a JAK2/STAT3 signaling pathway inhibitor. SD 1008 inhibits activation of STAT3, JAK2, and Src.Fórmula:C18H19NO5Pureza:98%Cor e Forma:SolidPeso molecular:329.35HJC0152 free base
CAS:<p>HJC0152 (free base) is an orally active, potent STAT3 inhibitor that impedes cell cycle progression, induces apoptosis, and notably reduces MDA-MB-231 xenograft</p>Fórmula:C15H13Cl2N3O4Pureza:98%Cor e Forma:SolidPeso molecular:370.19ERα antagonist 1
CAS:<p>ERα antagonist 1 is a selective, potent, covalent estrogen receptor alpha (ERα) antagonist that blocks the cell cycle of MCF-7 cells in G0/G1 phase and induces</p>Fórmula:C33H32N2O5SCor e Forma:SolidPeso molecular:568.68RET-IN-17
CAS:RET-IN-17 inhibits RET kinase; may help in IBS pain and RET-activated cancers.Fórmula:C27H28F4N4O4Cor e Forma:SolidPeso molecular:548.53TG2-179-1
CAS:Nalmefene (ORF 11676) is a μ-opioid antagonist and partial κ agonist used to study opioid overdose and alcohol dependence.Fórmula:C22H14ClFN4O2S2Cor e Forma:SolidPeso molecular:484.95CIL62
CAS:<p>CIL62 is a caspase-3/7-independent inducer of cell death. The mechanism of action of CIL62 is Necrostatin-1 dependent cell death [1].</p>Fórmula:C23H26O5Pureza:97.07%Cor e Forma:SolidPeso molecular:382.45HAPSBC
CAS:HAPSBC, an S-benzyl iron chelator, modulates the intracellular distribution of ^59Fe [1].Fórmula:C15H15N3S2Cor e Forma:SolidPeso molecular:301.43KRIBB3
CAS:KRIBB3: novel anticancer microtubule inhibitor; halts MDA-MB-231 cell migration/invasion by targeting Hsp27 phosphorylation.Fórmula:C19H19NO4Cor e Forma:SolidPeso molecular:325.36A-1293102
CAS:<p>A-1293102 is a potent, selective inhibitor of BCL-XL, effective in inducing apoptosis in tumor cells reliant on BCL-XL [1].</p>Fórmula:C42H40F3N7O7S5Cor e Forma:SolidPeso molecular:972.13HDAC-IN-53
CAS:HDAC-IN-53 inhibits HDAC1-3 with IC50s: 47, 125, 450 nM. Inactive on class II HDACs; triggers apoptosis; reduces tumor growth in mice.Fórmula:C23H20ClN7O2Pureza:98%Cor e Forma:SolidPeso molecular:461.9UNC3474
CAS:UNC3474, a small molecule ligand, selectively interacts with the aromatic methyl-lysine binding cage of the tumor protein 53BP1 Tudor domain (TT), exhibiting aFórmula:C17H28N2OCor e Forma:SolidPeso molecular:276.42MI-888 free base
CAS:MI-888 is the most potent MDM2 inhibitor (Ki = 0.44 nM), with high oral efficacy in human cancer models and optimal pharmacokinetics.Fórmula:C28H32Cl2FN3O3Cor e Forma:SolidPeso molecular:548.48Z-LLY-FMK
CAS:Z-LLY-FMK (Calpain Inhibitor IV) serves as an inhibitor of calpain, a family of proteases implicated in the apoptosis of various cell systems.Fórmula:C30H40FN3O6Pureza:98%Cor e Forma:SolidPeso molecular:557.65
