Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
VEGFR-2-IN-36
<p>VEGFR-2-IN-36 (compound 15) serves as a potent VEGFR-2 inhibitor, exhibiting an IC50 value of 0.067 μM, and acts as an apoptosis inducer with demonstrated</p>Fórmula:C24H23N7O5Pureza:98%Cor e Forma:SolidPeso molecular:489.48Thalidomide-O-PEG4-azide
CAS:Thalidomide-O-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].Fórmula:C23H29N5O9Pureza:98%Cor e Forma:SolidPeso molecular:519.5NTR 368
CAS:<p>cytoplasmic peptide of the neurotrophin receptor p75NTR</p>Fórmula:C69H124N22O19Pureza:98%Cor e Forma:SolidPeso molecular:1565.86Aromatase-IN-5
<p>Aromatase-IN-5 (Compound 10) is a potent inhibitor of aromatase with an IC50 value of 0.06 μM. It effectively blocks estrogen production and inhibits the proliferation of breast cancer cell lines such as MCF-7, arresting the cell cycle in the G1 phase and inducing apoptosis. Aromatase-IN-5 shows promise for breast cancer research.</p>Cor e Forma:Odour SolidPamrevlumab
CAS:<p>FG-3019 (Pamrevlumab), a human antibody, targets CTGF, potentially treating idiopathic pulmonary fibrosis.</p>Pureza:100% (SEC-HPLC) - 95%Cor e Forma:LiquidThalidomide-5,6-Cl
CAS:<p>Thalidomide-5,6-Cl is a cereblon ligand derivative that recruits CRBN protein and forms PROTACs with a linker.</p>Fórmula:C13H8Cl2N2O4Cor e Forma:SolidPeso molecular:327.12TAT-BH4 (Bcl-xL)
<p>TAT-BH4 (Bcl-xL), primarily localized at the mitochondria, inhibits apoptotic cell death.</p>Fórmula:C159H268N58O45Pureza:98%Cor e Forma:SolidPeso molecular:3712.19Halenaquinone
CAS:<p>Halenaquinone: PI3K inhibitor, stops RAD51 DNA binding & osteoclastogenesis, induces PC12 cell apoptosis.</p>Fórmula:C20H12O5Pureza:98%Cor e Forma:SolidPeso molecular:332.31CALP1
CAS:<p>Cell-permeable CaM agonist; activates phosphodiesterase, binds to Ca2+ channels, inhibits cytotoxicity (IC50=52μM), protects cells, reduces inflammation.</p>Fórmula:C40H75N9O10Pureza:98%Cor e Forma:SolidPeso molecular:842.09MDM2-IN-21
CAS:<p>MDM2-IN-21 is a potent MDM2 inhibitor. MDM2-IN-21 can be used for the research of cancer.</p>Fórmula:C34H40Cl2N4O2Cor e Forma:SolidPeso molecular:607.62Anti-Mouse PD-1 (LALA-PG) Antibody (RMP1-14)
<p>Anti-MousePD-1(LALA-PG) Antibody (RMP1-14) is an IgG2a, κ antibody inhibitor derived from mice that targets and inhibits mouse PD-1.</p>Cor e Forma:Odour LiquidTQB-2858
<p>TQB-2858 is a bifunctional fusion protein composed of an anti-PD-L1 monoclonal antibody fused with the extracellular domain of the TGF-β receptor. It exhibits high affinity for PD-L1, TGF-β1, and TGF-β3, and demonstrates a high target occupancy rate for PD-L1. TQB-2858 can be used in research on osteosarcoma and alveolar soft part sarcoma (ASPS).</p>Cor e Forma:Odour LiquidA011
<p>A011, a potent and selective ataxia-telangiectasia mutated (ATM) inhibitor, exhibits an IC50 of 1.0 nM and triggers apoptosis as well as G2/M phase cell cycle</p>Fórmula:C27H28N6OPureza:98%Cor e Forma:SolidPeso molecular:452.55Daporinad hydrochloride
CAS:<p>Daporinad hydrochloride (FK 866 hydrochloride) is a NAMPT inhibitor with antitumor and antiangiogenic activity that induces apoptosis in tumor cells.</p>Fórmula:C24H30ClN3O2Pureza:98.99%Cor e Forma:SolidPeso molecular:427.97Ferroptosis-IN-3
<p>Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM).</p>Pureza:98%Cor e Forma:Odour SolidC-Reactive Protein (CRP) (174-185)
CAS:<p>CRP protein and its fragment (174-185, RS-83277) boost human monocyte and macrophage cancer-killing effects in vitro.</p>Fórmula:C62H93N13O16Pureza:98%Cor e Forma:SolidPeso molecular:1276.48Caerin 1.1 TFA
<p>Caerin 1.1 TFA, a host defense peptide derived from the Australian tree frog Litoria's glandular secretions, exhibits anti-proliferative effects on HeLa cells</p>Pureza:98%Cor e Forma:Odour SolidEGFR-IN-153
<p>EGFR-IN-153 (Compound 5l) is an EGFR inhibitor that suppresses the proliferation of MDA-MB-231 cells with an IC50 of 0.73 μM and induces apoptosis. It is applicable for research in breast cancer.</p>Cor e Forma:Odour SolidPamlectabart
<p>Pamlectabart is a humanised antibody targeting TNFRSF17/BCMA, (ADC) Pamlectabart tismanitin multiple myeloma.</p>Pureza:95%Cor e Forma:Odour LiquidDCZ3301
CAS:<p>DCZ3301 is a novel aryl-guanidino inhibitor.</p>Fórmula:C20H16ClF3N6O2Pureza:99.89%Cor e Forma:SolidPeso molecular:464.83
