Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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EGCG-4″-sulfate
CAS:<p>EGCG-4″-sulfate, a predominant polyphenol in green tea, demonstrates notable anticancer, antioxidant, and anti-inflammatory effects, particularly against</p>Fórmula:C22H18O14SCor e Forma:SolidPeso molecular:538.43Reveromycin A
CAS:<p>Reveromycin A from Streptomyces sp. inhibits epidermal growth, tumors, and C. albicans; affects osteoclasts. IC50: 0.7-1.9 μg/ml; MIC: 2 μg/ml.</p>Fórmula:C36H52O11Cor e Forma:SolidPeso molecular:660.79Thalidomide-O-C7-acid
CAS:<p>Thalidomide-O-C7-acid: A cereblon ligand from Thalidomide linked via a PROTAC-used linker.</p>Fórmula:C21H24N2O7Cor e Forma:SolidPeso molecular:416.43Anti-inflammatory agent 35
CAS:<p>Anti-inflammatory agent 35 is a potent anti-inflammatory agent.</p>Fórmula:C27H29NO8Pureza:99.98%Cor e Forma:SoildPeso molecular:495.52Monactin
CAS:<p>Monactin is a Marcrotetrolide antibiotic produced by cycloheximide producing species of Streptomyces. It is a homolog of nonactin from the same species.</p>Fórmula:C41H66O12Pureza:98%Cor e Forma:SolidPeso molecular:750.96Tubulin inhibitor 34
<p>Tubulin Inhibitor 34 (compound b5), a potent anticancer agent, inhibits tubulin polymerization and induces G2/M arrest and apoptosis.</p>Fórmula:C21H22N4O3SCor e Forma:SolidPeso molecular:410.49PROTAC Mcl1 degrader-1
CAS:<p>PROTAC Mcl1 degrader-1 is a Cereblon ligand-based targeted chimeric protein degrader (PROTAC) and an Mcl-1 inhibitor, useful in cancer research.</p>Fórmula:C45H45BrN6O8SPureza:98.74%Cor e Forma:SolidPeso molecular:909.84EGFR-IN-151
<p>EGFR-IN-151 (Compound 10) inhibits EGFR and its downstream signaling pathways ERK/STAT3. It effectively suppresses the proliferation of various lung cancer cells, with IC50 values of 11.7, 5.19, 7.32, and 1.53 μM for NCI-H1781, HCC827, NCI-H3255, and NCI-H1975, respectively. Additionally, EGFR-IN-151 hinders colony formation and cell migration in H1975, induces G1 phase cell cycle arrest, and triggers apoptosis in H1975 cells.</p>Cor e Forma:Odour SolidUSP7-IN-9
<p>USP7-IN-9 is a potent USP7 inhibitor (IC50 = 40.8 nM), induces apoptosis, arrests RS4;11 cells, and modulates key oncoproteins.</p>Fórmula:C32H33ClF6N6O8Cor e Forma:SolidPeso molecular:779.08CWI1-2
CAS:<p>CWI1-2 is a potent IGF2BP2 inhibitor that inhibits its interaction with M6A-modified target transcripts by binding IGF2BP2.</p>Fórmula:C22H17Cl3N6O3Pureza:98.27%Cor e Forma:SoildPeso molecular:519.77PUMA BH3
<p>PUMA BH3 activates Bak, binds Bcl-2; triggers apoptosis via cytochrome C release; Kd 26 nM.</p>Fórmula:C128H202N42O43SPureza:98%Cor e Forma:SolidPeso molecular:3049.3CPTH2 (hydrochloride) (357649-93-5 free base)
CAS:<p>CPTH2 is an inhibitor of the HAT activity of Gcn5.</p>Fórmula:C14H15Cl2N3SPureza:98%Cor e Forma:SolidPeso molecular:328.26Minocycline
CAS:<p>Minocycline is a useful organic compound for research related to life sciences. The catalog number is T131626 and the CAS number is 10118-90-8.</p>Fórmula:C23H27N3O7Cor e Forma:SolidPeso molecular:457.48MNK8
CAS:<p>MNK8 is a potent STAT3 inhibitor, impairs DNA binding, and inhibits liver cancer cell growth.</p>Fórmula:C15H12N2O2Pureza:99.74%Cor e Forma:SolidPeso molecular:252.27Thalidomide-5-propoxyethanamine
CAS:<p>Thalidomide-5-propoxyethanamine acts as a cereblon (CRBN) ligand derived from Thalidomide, and it serves the purpose of recruiting the CRBN protein.</p>Fórmula:C18H21N3O5Cor e Forma:SolidPeso molecular:359.38XZ338
<p>XZ338 is a highly selective degrader targeting BCL-XL without degrading BCL-2. It exhibits an IC50 value of 3.7 nM against MOLT-4 cells and possesses antiproliferative properties, making it useful for cancer research.</p>Cor e Forma:Odour SolidYL5084
CAS:<p>YL5084 is a selective JNK2/3 inhibitor with IC50s: JNK2 (70 nM), JNK3 (84 nM), and antiproliferative, apoptosis-inducing effects.</p>Fórmula:C35H36N8O2Cor e Forma:SolidPeso molecular:600.71PF-543
CAS:<p>PF-543 (Sphingosine Kinase 1 Inhibitor II), a novel sphingosine-competitive inhibitor of SphK1, inhibits SphK1 with IC50 and Ki of 2.0 nM and 3.6 nM.</p>Fórmula:C27H31NO4SPureza:99.02%Cor e Forma:SolidPeso molecular:465.6eIF4E-IN-3
CAS:<p>eIF4E-IN-3: potent eIF4e inhibitor with promise for cancer study.</p>Fórmula:C34H30ClF3N6O4SCor e Forma:SolidPeso molecular:711.161-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea
CAS:<p>1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea 是一种能够激动 TNF-α的化合物，可以诱导细胞分泌 TNF-α。</p>Fórmula:C24H21ClF3N5OPureza:98.37% - 98.57%Cor e Forma:SoildPeso molecular:487.9
