Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5598 produtos de "Apoptose"
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XIAP BIR2/BIR2-3 inhibitor-3
CAS:<p>XIAP BIR2/BIR2-3 Inhibitor-3 functions as a dual inhibitor targeting both BIR2 and BIR2-3 domains, exhibiting potent activity with IC50 values below 1 nM. This compound is utilized in cancer research [1].</p>Fórmula:C86H106N18O16S2Cor e Forma:SolidPeso molecular:1712TNF-α (31-45), human
CAS:<p>TNF-α (31-45), human is a peptide of tumor necrosis factor-α.</p>Fórmula:C69H122N26O22Pureza:98%Cor e Forma:SolidPeso molecular:1667.895(E/Z)-Eltrombopag 13C4
CAS:<p>(E/Z)-Eltrombopag 13C4 is a mix of E/Z isotopologues, both 13C-labeled TPO receptor agonists for thrombocytopenia.</p>Fórmula:C25H22N4O4Cor e Forma:SolidPeso molecular:446.444Antagonist G TFA
<p>Potent vasopressin blocker, Antagonist G TFA also mildly inhibits GRP & Bradykinin, triggers AP-1, enhances chemo response.</p>Fórmula:C51H67F3N12O8SCor e Forma:SolidPeso molecular:1065.21Zamzetoclax
CAS:<p>Zamzetoclax (compound 1) acts as a potential inhibitor of Mcl-1.</p>Fórmula:C38H46ClN5O6SCor e Forma:SolidPeso molecular:736.32Thalidomide-NH-PEG3-COOH
CAS:<p>Thalidomide-NH-PEG3-COOH is a cereblon-based E3 ligase ligand-linker for PROTAC synthesis.</p>Fórmula:C22H27N3O9Cor e Forma:SolidPeso molecular:477.47CDC20-IN-2
<p>CDC20-IN-2 (14c) is an inhibitor of Cdc20 with a KD of 7.65 μM, inducing G2/M phase arrest, promoting DNA damage accumulation, and stabilizing key substrates such as Cyclin B1 and Bim. This leads to enhanced apoptosis, as well as inhibition of tumor cell proliferation and migration.</p>Cor e Forma:Odour SolidPROTAC MNK1 degrader-1
<p>ROTACMNK1degrader-1 is a selective MNK1 PROTAC degrader with a DC50 of 11.92 nM and a Dmax greater than 96% in MV4-11 cells. It significantly reduces p-eIF4E levels with an IC50 of 22.07 nM, induces apoptosis, and causes cell cycle arrest at the G1 phase. This compound exhibits potent antitumor activity, demonstrating strong anti-leukemic effects in MV4-11 xenograft mouse models with acceptable drug safety.</p>Fórmula:C35H38N6O6SCor e Forma:SolidPeso molecular:670.78Human PD-L1 inhibitor I
CAS:<p>Human PD-L1 inhibitor I, a peptide, blocks PD-L1/PD-1 interaction with 3.39 μM affinity.</p>Fórmula:C110H152N26O32Cor e Forma:SolidPeso molecular:2350.576Human PD-L1 inhibitor II
CAS:<p>Human PD-L1 inhibitor II is a potent PD-L1 inhibitor with anti-cancer activity.</p>Fórmula:C103H151N25O30Cor e Forma:SolidPeso molecular:2219.486BcI-2/BcI-xI ligand 1
CAS:<p>BcI-2/BcI-xI ligand 1, functioning as a BcI-2/BcI-xI ligand, is utilized in the synthesis of PROTAC BcI-2/BcI-xI Degrader-1 .</p>Fórmula:C53H64ClF3N6O8S3Cor e Forma:SolidPeso molecular:1101.75Fascaplysin chloride
CAS:<p>Fascaplysin inhibits CDK4/D1 (IC50=0.35μM), triggers caspase-activated autophagy-apoptosis crosstalk, and blocks PI3K/AKT/mTOR in HL-60 cells.</p>Fórmula:C18H11ClN2OCor e Forma:SolidPeso molecular:306.75PD-1/PD-L1-IN-48
<p>PD-1/PD-L1-IN-48 (compound HD10) is an effective inhibitor of the PD-1/PD-L1 interaction, exhibiting an IC50 of 3.1 nM. It plays a vital role in cancer research.</p>Cor e Forma:Odour SolidThalidomide-Piperazine 5-fluoride hydrochloride
CAS:<p>Thalidomide-Piperazine 5-fluoride hydrochloride, a derivative of the cereblon (CRBN) inhibitor Thalidomide, serves as a ligand for E3 ubiquitin ligase (Ligands for E3 Ligase), facilitating the synthesis of PROTACs [1].</p>Fórmula:C17H18ClFN4O4Cor e Forma:SolidPeso molecular:396.8fac-[Re(CO)3(L3)(H2O)][NO3]
<p>Fac-[Re(CO)3(L3)(H2O)][NO3] (Compound 3), a rhenium(I) tricarbonyl aqua complex, acts as an anticancer agent through the induction of mitochondrial dysfunction.</p>Fórmula:C25H17N6O8ReCor e Forma:SolidPeso molecular:715.64BODIPY FL thalidomide
CAS:<p>BODIPY FL thalidomide is a fluorescent probe that binds human cereblon protein with high affinity, exhibiting a dissociation constant (Kd) of 3.6 nM [1].</p>Fórmula:C37H43BF2N6O7Cor e Forma:SolidPeso molecular:732.58Antitumor photosensitizer-3
<p>Antitumor Photosensitizer-3 (Compound I), a chlorin derivative, effectively induces apoptosis and necrosis in tumor cells upon exposure to 650 nm laser</p>Fórmula:C48H34N4O4Cor e Forma:SolidPeso molecular:730.81LL-K9-3
CAS:<p>LL-K9-3, a selective hydrophobic tagging technology (HyT)-based degrader, specifically targets the CDK9-cyclin T1 complex, displaying DC50 values of 589 nM for</p>Fórmula:C31H49N5O6S3Cor e Forma:SolidPeso molecular:683.94Bursehernin
CAS:<p>Bursehernin is a useful organic compound for research related to life sciences and the catalog number is T124894.</p>Fórmula:C21H22O6Cor e Forma:SolidPeso molecular:370.401hCAIX-IN-13
CAS:<p>hCAIX-IN-13 (Pt2) inhibits CAIX with 6.57 μM IC50, curbs cancer cell growth, and induces apoptosis for cancer research.</p>Fórmula:C37H33F3N6O7PtS2Cor e Forma:SolidPeso molecular:989.9
