Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5600 produtos de "Apoptose"
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Ferroptosis-IN-17
<p>Ferroptosis-IN-17 (Compound 18) is an inhibitor of ferroptosis with an EC50 value of 0.57 μM. It effectively reduces the accumulation of intracellular ferrous ions and lipid peroxidation while restoring levels of glutathione (GSH) and glutathione peroxidase 4 (GPX4). In rat plasma, Ferroptosis-IN-17 demonstrates good solubility and notable metabolic stability. This compound holds potential for research in tumor suppression, neurodegenerative diseases, and cardiovascular disorders.</p>Fórmula:C21H26N4O5SCor e Forma:SolidPeso molecular:446.52RIPK2-IN-2
CAS:<p>RIPK2-IN-2, a RIP2 kinase PROTAC inhibitor, blocks proinflammatory signaling in autoinflammatory diseases.</p>Fórmula:C53H65FN14O7S2Cor e Forma:SolidPeso molecular:1093.3Vonlerizumab
<p>Vonlerizumab (Anti-TNFRSF4/OX40/CD134 Antibody) is a humanized monoclonal antibody targeting OX40, used in tumor research.</p>Pureza:>95%Cor e Forma:LiquidPeso molecular:145.5 kDaDesmethyl-WEHI-345 analog
CAS:<p>Desmethyl-WEHI-345 analog, a protein kinase inhibitor, holds potential for colon cancer research.</p>Fórmula:C22H23N7OCor e Forma:SolidPeso molecular:401.474Os30
<p>Os30 is a potent fourth-generation EGFR inhibitor, specifically targeting the EGFRC797S-TK mutation with IC50 values of 18 nM for EGFRDel19/T790M/C797S TK and</p>Pureza:98%Cor e Forma:Odour SolidViolacein
CAS:<p>Violacein, a purple antibacterial and antiprotozoal compound from C. violaceum, effective against Gram-positive bacteria and P. falciparum.</p>Fórmula:C20H13N3O3Cor e Forma:SolidPeso molecular:343.34Daporinad hydrochloride
CAS:<p>Daporinad hydrochloride (FK 866 hydrochloride) is a NAMPT inhibitor with antitumor and antiangiogenic activity that induces apoptosis in tumor cells.</p>Fórmula:C24H30ClN3O2Pureza:98.99%Cor e Forma:SolidPeso molecular:427.97Eriosematin
CAS:<p>Eriosematin has anti-proliferative and apoptosis-inducing properties and is a compound extracted from the root of Flemingia philippinensis in the Philippines.</p>Fórmula:C19H20O4Pureza:98%Cor e Forma:SolidPeso molecular:312.36Topoisomerase II inhibitor 14
CAS:<p>Topoisomerase II inhibitor 14: powerful anticancer agent that induces apoptosis, halts S phase, and lowers GSH, MDA, and NO levels.</p>Fórmula:C15H11Cl2N5Pureza:99.62%Cor e Forma:SoildPeso molecular:332.19Platycoside G3
CAS:<p>Platycoside G3 is a useful organic compound for research related to life sciences. The catalog number is T124100 and the CAS number is 849758-44-7.</p>Fórmula:C63H102O32Cor e Forma:SolidPeso molecular:1371.48Asparanin A
CAS:<p>Asparanin A, an apoptosis inducer with anticancer properties, arrests the cell cycle in the G0/G1 phase via the mitochondria and PI3K/AKT signaling pathways.</p>Fórmula:C39H64O13Pureza:98%Cor e Forma:SolidPeso molecular:740.92PTD-p65-P1 Peptide TFA
<p>Ptd-p65-p1 Peptide TFA inhibits NF-kappaB, has a cell-penetrating antennapedia sequence, and selectively blocks NF-kappaB activation.</p>Fórmula:C170H276F3N57O46SPureza:98%Cor e Forma:SolidPeso molecular:3943.52Tubulin inhibitor 34
<p>Tubulin Inhibitor 34 (compound b5), a potent anticancer agent, inhibits tubulin polymerization and induces G2/M arrest and apoptosis.</p>Fórmula:C21H22N4O3SCor e Forma:SolidPeso molecular:410.49Anticancer agent 130
<p>Anticancer agent 130 (compound 8d) significantly induces apoptosis in A549 cells [1].</p>Fórmula:C38H46FN5O5Pureza:98%Cor e Forma:SolidPeso molecular:671.8BK60106
<p>BK60106 is a selective and direct inhibitor of the transmembrane protein CD99, which causes cell death in Ewing Sarcoma cells.</p>Fórmula:C15H15FN6O3Pureza:99.30% - >99.99%Cor e Forma:SolidPeso molecular:346.32PERK-IN-6
CAS:<p>PERK-IN-6 is a novel and highly potent PERK inhibitor (IC50:2.5 nM).</p>Fórmula:C23H22N6OPureza:99.62% - 99.92%Cor e Forma:SolidPeso molecular:398.46MALT1-IN-13
<p>MALT1-IN-13 (compound 10m) is an inhibitor of the mucosa-associated lymphoid tissue lymphoma translocation protein (MALT1), forming a covalent and irreversible bond with the MALT1 protease, thereby inhibiting its activity with an IC50 of 1.7 μM. It suppresses the proliferation of ABC-DLBCL and induces apoptosis in ABC-DLBCL HBL1 cells. Additionally, MALT1-IN-13 regulates the mTOR and PI3K-Akt pathways.</p>Fórmula:C20H15BrClN3O3S2Peso molecular:522.94267JPS014 TFA
<p>JPS014 TFA, a benzamide-based Von Hippel-Lindau (VHL) E3-ligase proteolysis targeting chimera (PROTAC), effectively degrades class I histone deacetylase (HDAC</p>Fórmula:C48H60F3N7O9SPureza:98%Cor e Forma:SolidPeso molecular:968.09RO7567132
<p>RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.</p>Cor e Forma:Odour LiquidCWI1-2 HCL
CAS:<p>CWI1-2 HCL: Potent IGF2BP2 inhibitor, induces apoptosis/differentiation, targets leukemia therapy.</p>Fórmula:C22H18Cl4N6O3Pureza:98.09%Cor e Forma:SolidPeso molecular:556.23
