Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5600 produtos de "Apoptose"
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ABBV-167
CAS:<p>ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax.</p>Fórmula:C46H53ClN7O11PSCor e Forma:SolidPeso molecular:978.45TTQ-SA
<p>TTQ-SA is a near-infrared spiraling aggregation-induced emitter capable of converting near-infrared light (NIR) into thermal energy, resulting in thermal damage and death of tumor cells. In cancer cells MF-7, TTQ-SA shows cell uptake and targeting capabilities. TTQ-SA binds with DNAzyme to inhibit the expression of the survivin gene, enhancing the sensitivity of tumor cells to photothermal therapy.</p>Fórmula:C78H53N7SCor e Forma:SolidPeso molecular:1120.37Anticancer agent 137
<p>Anticancer agent 137 (8q), a potent PI3k inhibitor, exhibits broad-spectrum anticancer activity by inducing G2/M cell cycle arrest and apoptosis.</p>Fórmula:C26H27NO6Pureza:98%Cor e Forma:SolidPeso molecular:449.5Solasodine hydrochloride
CAS:<p>Solasodine hydrochloride (90 μM; 2 days) treatment induced significant budding in P19 cells. This compound strongly stimulated the expression of various neuronal markers, including βIII-tubulin, synaptophysin, MAP2, ChAT, and the neural progenitor marker doublecortin. Predominantly, Solasodine hydrochloride directed the differentiation of P19 cells towards neuronal pathways.</p>Fórmula:C27H44ClNO2Cor e Forma:SolidPeso molecular:450.1TNF-α (31-45), human
CAS:<p>TNF-α (31-45), human is a peptide of tumor necrosis factor-α.</p>Fórmula:C69H122N26O22Pureza:98%Cor e Forma:SolidPeso molecular:1667.895Latikafusp
CAS:<p>Latikafusp (AMG 256) is a fusion protein that is a PD-1 blocker and IL-21R agonist with antitumor activity.</p>Pureza:97.1% (SDS-PAGE); 97.4% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.4% (SEC-HPLC)Cor e Forma:LiquidAnti-inflammatory agent 42
CAS:<p>Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.</p>Fórmula:C20H12N2OSPureza:98.13%Cor e Forma:SolidPeso molecular:328.39GSK-1070916
CAS:<p>GSK-1070916 (GSK-1070916A) is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3.5 nM/6.5 nM.</p>Fórmula:C30H33N7OPureza:99.73%Cor e Forma:SolidPeso molecular:507.63c-Met-IN-24
<p>c-Met-IN-24 (compound 3g) serves as a dual-target inhibitor for STAT-3 (=4.7 μM) and c-MET (=12.67 μM), exhibiting anticancer properties. It arrests the G2/M cell cycle and induces apoptosis in SNB-75 cells, making it applicable in the research of central nervous system cancers.</p>Fórmula:C20H15ClN4O4SCor e Forma:SolidPeso molecular:442.88Acrixolimab
CAS:<p>Acrixolimab is a humanized IgG4-κ monoclonal antibody that selectively targets PD-1 [1] [2].</p>Pureza:98%Cor e Forma:LiquidBoc-AEVD-CHO
CAS:<p>Boc-AEVD-CHO, a selective Caspase 8 inhibitor, facilitates apoptosis research and the investigation of immune and inflammatory diseases [1] [2].</p>Fórmula:C22H36N4O10Pureza:98%Cor e Forma:SolidPeso molecular:516.54Thalidomide-O-amido-PEG4-azide
CAS:<p>Thalidomide-O-amido-PEG4-azide is a polyethylene glycol (PEG) derivative serving as a linker for Proteolysis Targeting Chimeras (PROTACs) synthesis [1].</p>Fórmula:C25H32N6O10Pureza:98%Cor e Forma:SolidPeso molecular:576.56Antiangiogenic agent 6
Antiangiogenic agent 6 (Pt-1) effectively inhibits angiogenesis and induces necroptosis in tumor cells.Fórmula:C37H24F6N3PPtCor e Forma:SolidPeso molecular:850.66BK60106
<p>BK60106 is a selective and direct inhibitor of the transmembrane protein CD99, which causes cell death in Ewing Sarcoma cells.</p>Fórmula:C15H15FN6O3Pureza:99.30% - >99.99%Cor e Forma:SolidPeso molecular:346.32Atibuclimab
CAS:<p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:145.28 kDaSincalide ammonium
CAS:<p>Sincalide ammonium, a CCK analog, stimulates bile release, gallbladder contraction, and sphincter relaxation, aiding in diagnoses.</p>Fórmula:C49H65N11O16S3Pureza:98.46%Cor e Forma:SolidPeso molecular:1160.3(-)-Irofulven
CAS:<p>Irofulven is an agent of DNA-damaging and antitumor. It is used for the treatment of advanced solid tumors, including prostate, ovarian, and pancreatic cancers.</p>Fórmula:C15H18O3Cor e Forma:SolidPeso molecular:246.30MD-222
CAS:<p>MD-222: a first-in-class, highly potent PROTAC that degrades MDM2, activates p53, and exhibits anticancer properties.</p>Fórmula:C48H47Cl2FN6O6Cor e Forma:SolidPeso molecular:893.84PROTAC Bcl-xL degrader-3
CAS:<p>PROTAC Bcl-xL degrader-3 is a potent ROTAC Bcl-xL degrader.</p>Fórmula:C82H105ClF3N11O11S4Cor e Forma:SolidPeso molecular:1641.49Giloralimab
CAS:<p>Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.</p>Pureza:95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Cor e Forma:Liquid
