Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(127 produtos)
- FOXO1(3 produtos)
- IAP(65 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(24 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(91 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5622 produtos de "Apoptose"
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PD-1/PD-L1-IN-39
<p>PD-1/PD-L1-IN-39 (X 14) is an orally active PD-1/PD-L1 inhibitor with an IC50 value of 15.73 nM. It exhibits strong binding affinity to human and mouse PD-L1, with KD values of 14.62 and 392 nM, respectively. PD-1/PD-L1-IN-39 also demonstrates antitumor activity.</p>Fórmula:C23H20ClFN2O3Peso molecular:426.11465PERK-IN-6
CAS:<p>PERK-IN-6 is a novel and highly potent PERK inhibitor (IC50:2.5 nM).</p>Fórmula:C23H22N6OPureza:99.62% - 99.92%Cor e Forma:SolidPeso molecular:398.46YX-02-030
CAS:<p>YX-02-030M is a PROTACMDM2 degrader. It inhibits the binding of MDM2 to p53 and VHL to HIF1α, with IC50 values of 63 nM and 1.35 μM, respectively. YX-02-030M binds to MDM2 and recruits the VHL E3 ubiquitin ligase to initiate MDM2 degradation, effectively killing p53 mutant or deficient triple-negative breast cancer (TNBC) cells.</p>Fórmula:C66H85Cl2N9O10SPeso molecular:1267.41Thalidomide-NH-C8-NH2
CAS:<p>Thalidomide-NH-C8-NH2 is a synthetic E3 ligase ligand-linker for PROTAC, combining cereblon ligand and a specific linker.</p>Fórmula:C21H28N4O4Cor e Forma:SolidPeso molecular:400.479Anti-inflammatory agent 42
CAS:<p>Anti-inflammatory agent 42 has anti-inflammatory activity and inhibits the expression of TNF-α and IL-6 in LPS-stimulated macrophages.</p>Fórmula:C20H12N2OSPureza:98.13%Cor e Forma:SolidPeso molecular:328.39EGFR/HER2/DHFR-IN-3
<p>EGFR/HER2/DHFR-IN-3 (compound 4c) serves as an efficacious dual inhibitor specifically targeting EGFR/HER2, exhibiting IC50 values of 0.138 μM for EGFR and 0.</p>Pureza:98%Cor e Forma:Odour SolidOligomycin B
CAS:Oligomycin B is an antibiotic isolated from marine Streptomyces, is an eukaryotic ATP synthase inhibitor, induces apoptosis.Fórmula:C45H72O12Pureza:98%Cor e Forma:SolidPeso molecular:805.05Enniatin A1
CAS:Enniatin A1, a cyclic hexadepsipeptide from Fusarium, induces apoptosis and disrupts ERK, inhibiting ACAT (IC50: 49 μM).Fórmula:C35H61N3O9Pureza:98%Cor e Forma:SolidPeso molecular:667.885N-Stearoyltyrosine
CAS:<p>N-Stearoyltyrosine (N-(1-Oxooctadecyl)-L-tyrosine) is an analog of Anandamide. It exhibits neuroprotective effects by safeguarding the CA1 region of the hippocampus in a gerbil ischemia-reperfusion model. Additionally, N-Stearoyltyrosine inhibits free radical generation, enhances antioxidant capacity, and reduces IR-induced apoptosis (cell apoptosis).</p>Fórmula:C27H45NO4Cor e Forma:SolidPeso molecular:447.65SRE-II
<p>SRE-II, an amide derivative, serves as an activatable photosensitizer tailored for photodynamic cancer research, exhibiting diminished fluorescence and</p>Fórmula:C15H9ClINO2Pureza:98%Cor e Forma:SolidPeso molecular:397.59Tubulin/HDAC-IN-2
<p>Tubulin/HDAC-IN-2 (Compound II-19k) is a dual inhibitor targeting Tubulin and HDAC, exhibiting IC50 values of 0.403 μM for HDAC1, 0.591 μM for HDAC2, 3.552 μM</p>Fórmula:C21H19FN2O4Cor e Forma:SolidPeso molecular:382.38HDAC6-IN-16
<p>HDAC6-IN-16 (compound 5c), a quinazolin-4(3H)-one-based inhibitor of histone deacetylase 6 (HDAC6), demonstrates an anticancer effect by inhibiting colony</p>Fórmula:C23H19N3O3SPureza:98%Cor e Forma:SolidPeso molecular:417.48Thymidine 3',5'-disphosphate
CAS:<p>pdTp is a highly selective, small-molecule miRNA regulatory complex RISC subunit SND1 inhibitor.</p>Fórmula:C10H16N2O11P2Cor e Forma:SolidPeso molecular:402.194-hydroperoxy cyclophosphamide
CAS:<p>4-hydroperoxy cyclophosphamide (4-OOH-CY) induces hepatotoxicity. It increases ghrelin levels and enhances inflammatory factors and oxidative markers.</p>Fórmula:C7H15Cl2N2O4PPureza:98%Cor e Forma:SolidPeso molecular:293.09VPC-70063
CAS:<p>VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.</p>Fórmula:C16H12F6N2SPureza:99.98%Cor e Forma:SolidPeso molecular:378.34PD0166285 dihydrochloride
CAS:<p>PD-166285 is an effective and broadly active inhibitor of protein tyrosine kinase.</p>Fórmula:C26H29Cl4N5O2Cor e Forma:SolidPeso molecular:585.35Sandacanol
CAS:Sandacanol (Sandranol) is an olfactory receptor (OR10H1) agonist.Sandacanol induces cell cycle arrest and partial apoptosis in bladder cancer cells.Fórmula:C14H24OPureza:99.59%Cor e Forma:SolidPeso molecular:208.34Tilogotamab
CAS:<p>Tilogotamab (GEN-1029) is an agonistic hexameric complex targeting two independent epitopes on DR5, used for studying multiple myeloma (MM).</p>Pureza:95%Cor e Forma:LiquidPOV-PC
CAS:<p>POV-PC is an oxidized phospholipid that inhibits VSMC growth under high serum conditions and induces cell apoptosis under low serum conditions.</p>Fórmula:C29H56NO9PCor e Forma:SolidPeso molecular:593.73Z-Asp-CH2-DCB
CAS:<p>Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.</p>Fórmula:C20H17Cl2NO7Pureza:99.08%Cor e Forma:SolidPeso molecular:454.26
