CymitQuimica logo
Apoptose

Apoptose

Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.

Subcategorias de "Apoptose"

Exibir 6 mais subcategorias

Foram encontrados 5622 produtos de "Apoptose"

Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
produtos por página.
  • 7-Methoxy-1-tetralone
    Targetmol
    + Info

    7-Methoxy-1-tetralone

    CAS:
    <p>7-Methoxy-1-tetralone may have insecticidal activity.</p>
    Fórmula:C11H12O2
    Pureza:99.85% - 99.89%
    Cor e Forma:White Crystal
    Peso molecular:176.21

    Ref: TM-Fr12275

  • Cefatrizine
    Targetmol
    + Info

    Cefatrizine

    CAS:
    <p>Cefatrizine inhibits eEF-2 kinase, affecting apoptosis, autophagy, and ER stress in cancers.</p>
    Fórmula:C18H18N6O5S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:462.5

    Ref: TM-T26973

  • PROTAC FLT-3 degrader 1
    Targetmol
    + Info

    PROTAC FLT-3 degrader 1

    CAS:
    <p>PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 nM),with anti-proliferative activity.</p>
    Fórmula:C52H61N9O9S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1020.23

    Ref: TM-T12555

  • KB02-SLF
    Targetmol
    + Info

    KB02-SLF

    <p>KB02-SLF, a molecular glue, degrades nuclear FKBP12 by modifying E3 ligase DCAF16 and extends protein degradation.</p>
    Fórmula:C50H65ClN4O12
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:949.52

    Ref: TM-T18061

  • Fosbretabulin [free base]
    Targetmol
    + Info

    Fosbretabulin [free base]

    CAS:
    <p>Fosbretabulin is a natural cis-stilbene that interferes with cellular tubulin dynamics and selectively destroys tumor blood vessels.</p>
    Fórmula:C18H21O8P
    Cor e Forma:Solid
    Peso molecular:396.33

    Ref: TM-T31857

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    QZ2135

    <p>QZ2135 (compound 20) is a PROTAC degrader that specifically targets RET and exhibits antitumor activity in vivo within a Ba/F3-KIF5B-RET-G810C xenograft mouse model. The compound demonstrates degradation activity with DC50 values of 4.7 nM (WT), 17.2 nM (V804M), and 73.8 nM (G810C) when targeting KIF5B-RET. QZ2135 is composed of the target protein ligand (red part) RETligand-3, the E3 ligase ligand (blue part) Lenalidomide-F, and the PROTAC Linker (black part) 7-Iodohept-1-yne, wherein the target protein ligand combined with the linker forms the conjugate RETLigand-Linker Conjugate-1.</p>
    Fórmula:C53H54N12O4
    Cor e Forma:Solid
    Peso molecular:923.07

    Ref: TM-T205359

  • Osajin
    Targetmol
    + Info

    Osajin

    CAS:
    <p>Osajin is the major bioactive iso avone present in the fruit of Maclura pomifera. It has antitumor, antioxidant, and anti-inflammatory activities.</p>
    Fórmula:C25H24O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:404.46

    Ref: TM-T16407

  • Targaprimir-96
    Targetmol
    + Info

    Targaprimir-96

    CAS:
    <p>Targaprimir-96 is a potent microRNA-96 (miR-96) processing inhibitor.</p>
    Fórmula:C77H102N18O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1391.75

    Ref: TM-T13085

  • β-Amyloid (1-40) (rat)
    Targetmol
    + Info

    β-Amyloid (1-40) (rat)

    CAS:
    <p>Rat form of the beta-Amyloid (1-40) peptide</p>
    Fórmula:C190H291N51O57S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:4233.76

    Ref: TM-TP1441

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    ZZM-1220

    <p>ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP.</p>
    Fórmula:C25H29N5O3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:447.53

    Ref: TM-T79776

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    VEGFR-2-IN-68

    <p>VEGFR-2-IN-68 (13b) is an inhibitor of VEGFR-2 with an IC50 value of 41.51 nM. It can induce apoptosis and cause G2/M cell cycle arrest, as well as exhibit anti-cancer metastasis properties.</p>
    Fórmula:C27H25N5O2S
    Cor e Forma:Solid
    Peso molecular:483.1729

    Ref: TM-T207599

  • Thalidomide-O-PEG4-NHS ester
    Targetmol
    + Info

    Thalidomide-O-PEG4-NHS ester

    CAS:
    Thalidomide-O-PEG4-NHS ester is a polyethylene glycol (PEG)-based linker, commonly employed for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
    Fórmula:C28H33N3O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:619.57

    Ref: TM-T18830

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    BIO8898

    <p>BIO8898: potent CD40-CD154 inhibitor, IC50 of 25 µM, prevents CD40L-induced apoptosis.</p>
    Fórmula:C53H64N8O6
    Cor e Forma:Solid
    Peso molecular:909.13

    Ref: TM-T73866

  • JAK05
    Targetmol
    + Info

    JAK05

    JAK05 exhibits inhibitory activity against Helicobacter pylori, effectively suppressing strains J63, J196, and J107, with a MIC of 3-5 µg/mL. It shows affinity for binding to H+/K+-ATPase, COX-1/2, TNF-α, and PGE2, and possesses antioxidant and anti-inflammatory properties. In a rat model of ethanol-induced gastric ulcers, JAK05 demonstrates anti-ulcer activity.
    Fórmula:C27H27ClN4O9S
    Cor e Forma:Solid
    Peso molecular:619.043

    Ref: TM-T204688

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    GSK-3β inhibitor 15

    <p>GSK-3β inhibitor 15 (Compound 54), with an IC50 of 3.4 nM, effectively suppresses Aβ 1-42-induced phosphorylation of GSK-3β and tau protein, as well as LPS-</p>
    Fórmula:C17H16N6OS
    Cor e Forma:Solid
    Peso molecular:352.41

    Ref: TM-T78874

  • SF1126
    Targetmol
    + Info

    SF1126

    CAS:
    <p>SF1126 is a first-in-class PI3K/BRD4 inhibitor and RGDS-conjugated LY294002 prodrug, enhancing solubility and targeting tumor integrins.</p>
    Fórmula:C39H48N8O14
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:852.84

    Ref: TM-T16875

  • HDAC-IN-57
    Targetmol
    + Info

    HDAC-IN-57

    CAS:
    <p>HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4</p>
    Fórmula:C21H19N3O4
    Pureza:98.38%
    Cor e Forma:Soild
    Peso molecular:377.39

    Ref: TM-T77334

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Mcl-1 inhibitor 14

    <p>Compound (Ra)-10, also known as Mcl-1 inhibitor 14, is a potent inhibitor of myeloid cell leukemia-1 (MCL-1), exhibiting a K_i of 0.018 nM, and holds potential</p>
    Fórmula:C39H41ClFN5O5S
    Cor e Forma:Solid
    Peso molecular:746.29

    Ref: TM-T79215

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    Nrf2 activator-9

    <p>Nrf2 activator-9 (compound D-36) is an agent that mitigates oxidative stress by inhibiting the apoptosis of HUVEC cells induced by oxidized low-density</p>
    Fórmula:C26H27N5O4
    Cor e Forma:Solid
    Peso molecular:473.52

    Ref: TM-T79702

  • Logotipo do CymitQuimica
    Targetmol
    + Info

    SB-1295

    <p>SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 μM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells.</p>
    Fórmula:C23H22ClNO6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:443.88

    Ref: TM-T79287