Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(127 produtos)
- FOXO1(3 produtos)
- IAP(65 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(24 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(91 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5622 produtos de "Apoptose"
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Moracin N
CAS:<p>Moracin N, a ferroptosis inhibitor derived from mulberry leaves, exhibits neuroprotective activity by mitigating oxidative stress [1].</p>Fórmula:C19H18O4Pureza:98%Cor e Forma:SolidPeso molecular:310.34Angiogenesis inhibitor 3
CAS:<p>Angiogenesis Inhibitor 3 (compound 8) is a potent anti-cancer agent, blocking HUVEC/HCT-15 cell growth and inducing apoptosis.</p>Fórmula:C44H42BrN3O9Cor e Forma:SolidPeso molecular:836.72TG101209 analog 1
<p>TG101209 analog 1 (Compound 8h) serves as an inhibitor of BUB1B, exhibiting an IC50 of 10.36 μM. It also possesses cytotoxic properties, demonstrated by an IC50 of 1.347 μM against Caki-1 cells, and can induce necrosis and apoptosis.</p>Fórmula:C24H31N5O5SCor e Forma:SolidPeso molecular:501.598PROTAC SMARCA2/4 degrader-38
<p>PROTACSMARCA2/4 degrader-38 is a SMARCA2/4 PROTAC degrader with DC50 values of 3.0 nM and 4.0 nM, respectively. It facilitates the ubiquitination and degradation of SMARCA2/4 and can block the G0/G1 phase of the cell cycle, leading to the induction of apoptosis. PROTACSMARCA2/4 degrader-38 is applicable in acute myeloid leukemia (AML) research.</p>Cor e Forma:Odour Solidtetrathiomolybdate
CAS:<p>Tetrathiomolybdate (TM) promotes the dimerization of the metal-binding domain (WLN4) of the cellular copper efflux protein ATP7B through its characteristic</p>Fórmula:MoS4Cor e Forma:SolidPeso molecular:224.2Bim BH3, Peptide IV
CAS:<p>This Bim peptide belongs to the pro-apoptotic group of the Bcl-2 family of proteins.</p>Fórmula:C145H222N44O41SPureza:98%Cor e Forma:SolidPeso molecular:3269.65RIPK2-IN-2
CAS:<p>RIPK2-IN-2, a RIP2 kinase PROTAC inhibitor, blocks proinflammatory signaling in autoinflammatory diseases.</p>Fórmula:C53H65FN14O7S2Cor e Forma:SolidPeso molecular:1093.3cis-Clovamide
CAS:<p>cis-Clovamide is a naturally occurring phenolic compound with noteworthy antioxidant, anti-inflammatory, and antiapoptotic properties.</p>Fórmula:C18H17NO7Cor e Forma:SolidPeso molecular:359.334Anticancer agent 273
<p>Anticanceragent 273 (Compound 9q) is an effective anticancer compound identified from matrine. It inhibits cancer cell proliferation, with an IC50 of 4.48 μM against HeLa cells. Anticanceragent 273 exerts its anticancer effects by modulating PI3K/AKT expression and activating activating transcription factor 4 (ATF4), which induces endoplasmic reticulum stress and triggers apoptosis. It holds potential for cancer research, including cervical cancer.</p>Cor e Forma:Odour SolidMRIA9
CAS:<p>MRIA9 inhibits SIK1/2/3 & PAK2/3 with IC50: SIK1 (516 nM), SIK2 (180 nM), SIK3 (127 nM); ATP-competitive.</p>Fórmula:C24H22ClFN6O3Cor e Forma:SolidPeso molecular:496.92UBX1325
CAS:<p>UBX1325, a potent Bcl-xL inhibitor, induces cell death in aging cells, useful for age-related eye disease research.</p>Fórmula:C53H59ClF3N6O10PS3Cor e Forma:SolidPeso molecular:1159.69Thalidomide-PEG2-C2-NH2 hydrochloride
CAS:Thalidomide-based cereblon ligand with 2-unit PEG linker for PROTAC, in hydrochloride form.Fórmula:C19H25ClN4O6Pureza:98%Cor e Forma:SolidPeso molecular:440.88eIF4E-IN-2
CAS:<p>eIF4E-IN-2 effectively inhibits eIF4e, crucial for research on diseases like cancer.</p>Fórmula:C37H33ClF2N8O4S2Cor e Forma:SolidPeso molecular:791.29DB2115 tertahydrochloride
CAS:<p>DB2115 (tertahydrochloride) inhibits PU.1, key in leukemia; potential for cancer research.</p>Fórmula:C32H34Cl4N8O2Cor e Forma:SolidPeso molecular:704.48Violacein
CAS:<p>Violacein, a purple antibacterial and antiprotozoal compound from C. violaceum, effective against Gram-positive bacteria and P. falciparum.</p>Fórmula:C20H13N3O3Cor e Forma:SolidPeso molecular:343.34TRP-601
CAS:<p>TRP-601 is a caspase inhibitor.</p>Fórmula:C40H48F2N6O11Pureza:98%Cor e Forma:SolidPeso molecular:826.852MET/PDGFRA-IN-1
<p>MET/PDGFRA-IN-1 (compound 8c) serves as an inhibitor of MET and PDGFRA proteins, displaying an IC50 of 36 μM against MET.</p>Fórmula:C26H23N7OPureza:98%Cor e Forma:SolidPeso molecular:449.511-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea
CAS:<p>1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea 是一种能够激动 TNF-α的化合物，可以诱导细胞分泌 TNF-α。</p>Fórmula:C24H21ClF3N5OPureza:98.37% - 98.57%Cor e Forma:SoildPeso molecular:487.9Lenercept
CAS:<p>Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].</p>Cor e Forma:LiquidPUMA BH3
PUMA BH3 activates Bak, binds Bcl-2; triggers apoptosis via cytochrome C release; Kd 26 nM.Fórmula:C128H202N42O43SPureza:98%Cor e Forma:SolidPeso molecular:3049.3
