Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(127 produtos)
- FOXO1(3 produtos)
- IAP(65 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(24 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(91 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5622 produtos de "Apoptose"
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Eldecalcitol
CAS:<p>Eldecalcitol, orally active vitamin D analog, boosts bone density and treats osteoporosis.</p>Fórmula:C30H50O5Pureza:98%Cor e Forma:SolidPeso molecular:490.72LIB3S0280
<p>LIB3S0280 is a potent inhibitor of TBK1, with an IC50 of 493.9 nM. It suppresses TBK1 downstream signaling by reducing the phosphorylation of IκBα and AKT. LIB3S0280 causes G2/M phase arrest and induces apoptosis in pancreatic cancer cells. Notably, it exhibits significant inhibitory effects on pancreatic cancer cell lines with high TBK1 expression, with a 96-hour IC50 value ranging from 6.64-10.98 μM. LIB3S0280 shows potential for research in pancreatic ductal adenocarcinoma (PDAC).</p>Cor e Forma:Odour SolidApoptosis inducer 13
<p>Apoptosis Inducer 13 (Compound Ru4) promotes apoptosis in cancer cells while also suppressing their migration and invasion.</p>Fórmula:C59H54ClF6N8O4PRuPureza:98%Cor e Forma:SolidPeso molecular:1220.6DJ4
CAS:<p>DJ4 induces a dose-dependent pro-apoptotic effect in the micromolar range.</p>Fórmula:C19H16N4OSPureza:≥98%Cor e Forma:SoildPeso molecular:348.42Aphidicolin
CAS:<p>Aphidicolin blocks DNA synthesis, hinders herpes virus growth, and stimulates apoptosis in leukemia cells; it's a mold-derived DNA polymerase inhibitor.</p>Fórmula:C20H34O4Pureza:>99.99%Cor e Forma:SolidPeso molecular:338.48Multi-kinase-IN-4
<p>Multi-kinase-IN-4 (compound 5d) is a multi-targeted kinase inhibitor active against VEGFR2, EGFR, HER2, and CDK2, with respective IC50 values of 0.33, 0.22, 0.</p>Fórmula:C21H20ClFN2OSPureza:98%Cor e Forma:SolidPeso molecular:402.914-Epianhydrotetracycline hydrochloride
CAS:<p>EATC, a tetracycline byproduct, combats Pseudomonas to E. coli with MIC50s of 0.75-16 mg/L.</p>Fórmula:C22H23ClN2O7Cor e Forma:SolidPeso molecular:462.88BM-1244
CAS:<p>BM-1244 is a potent Bcl-xL/Bcl-2 inhibitor with Kis of 134 and 450 nM for Bcl- xL and Bcl-2, respectively.</p>Fórmula:C54H59ClF4N6O8S4Cor e Forma:SolidPeso molecular:1159.78β-Glucuronide-dPBD-PEG5-NH2
CAS:<p>β-Glucuronide-dPBD-PEG5-NH2 is a β-glucuronide-linked pyrrolobenzodiazepine dimer that functions as a proagent for the synthesis of the antibody-drug conjugate</p>Fórmula:C78H101N7O35Cor e Forma:SolidPeso molecular:1696.66Z-Asp-CH2-DCB
CAS:<p>Z-Asp-CH2-DCB is an irreversible inhibitor of broad spectrum caspase.</p>Fórmula:C20H17Cl2NO7Pureza:99.08%Cor e Forma:SolidPeso molecular:454.26HDAC6 degrader-5
<p>HDAC6degrader-5 (Compound 6) exhibits inhibitory and degradative activity against HDAC6, with an IC50 of 4.95 nM and a DC50 of 0.96 nM. It suppresses the release of TNF-α, IL-1β, and IL-6, and prevents apoptosis in liver cells. Additionally, HDAC6degrader-5 demonstrates anti-inflammatory properties in a mouse model of APAP-induced liver injury.</p>Fórmula:C21H22N4O3Cor e Forma:SolidPeso molecular:378.424H3B-8800
CAS:<p>H3B-8800 is an SF3B1 modulator that can be used to study transfusion-dependent anemia.</p>Fórmula:C31H45N3O6Pureza:98.31%Cor e Forma:SoildPeso molecular:555.712,2'-Dihydroxy chalcone
CAS:<p>2,2'-Dihydroxy chalcone inhibits β-glucuronidase (IC50=1.6 μM) and lysozyme (IC50=1.4 μM), and fights E. coli, S. fowleri, S. albicans, S. aureus.</p>Fórmula:C15H12O3Pureza:99.7%Cor e Forma:SolidPeso molecular:240.25PROTAC GPX4 degrader-1
CAS:PROTAC GPX4 Degrader-1 (DC-2) is a PROTAC-based compound that efficiently degrades GPX4, demonstrating a degradation concentration (DC 50) of 0.03 μM in HT1080Fórmula:C50H57ClN10O10Cor e Forma:SolidPeso molecular:993.5HDAC3-IN-2
<p>HDAC3-IN-2 (compound 4i), a pyrazinyl hydrazide-based HDAC3 inhibitor with an IC50 of 14 nM, effectively targets triple-negative breast cancer cells.</p>Fórmula:C16H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:315.37Thalidomide-O-C6-NH2
CAS:<p>Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate used in the PROTAC dTAG-13, a degrader of FKBP12F36V and BET[1].</p>Fórmula:C19H23N3O5Pureza:98%Cor e Forma:SolidPeso molecular:373.4HDAC6-IN-22
<p>HDAC6-IN-22 (compound 30), an HDAC6 inhibitor, exhibits an IC50 of 4.63 nM and demonstrates antiproliferative effects against multiple myeloma both in vitro and</p>Fórmula:C24H24N4O2Pureza:98%Cor e Forma:SolidPeso molecular:400.47Pimagedine
CAS:<p>Pimagedine is a prototype therapeutic agent for the prevention of formation of advanced glycation endproducts.</p>Fórmula:CH6N4Cor e Forma:SolidPeso molecular:74.09SB-1295
<p>SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 μM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells.</p>Fórmula:C23H22ClNO6Pureza:98%Cor e Forma:SolidPeso molecular:443.88Anti-inflammatory agent 61
<p>Compound 5b (Anti-inflammatory agent 61) is a potent anti-inflammatory agent that diminishes TNF-α expression in LPS-induced inflammation within RAW 264.7 cells</p>Cor e Forma:Odour Solid
