Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(127 produtos)
- FOXO1(3 produtos)
- IAP(65 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(24 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(91 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5622 produtos de "Apoptose"
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Z-WEHD-FMK
CAS:Z-WEHD-FMK is a cell-permeable and irreversible inhibitor of caspase-1/5. It also shows a robust inhibitory effect on cathepsin B activity (IC50: 6 μM).Fórmula:C37H42FN7O10Pureza:98%Cor e Forma:SolidPeso molecular:763.78Violacein
CAS:<p>Violacein, a purple antibacterial and antiprotozoal compound from C. violaceum, effective against Gram-positive bacteria and P. falciparum.</p>Fórmula:C20H13N3O3Cor e Forma:SolidPeso molecular:343.34PAK4-IN-3
<p>PAK4-IN-3 (compound 27e) is a PAK4 inhibitor exhibiting an IC50 of 10 nM and demonstrates antiproliferative effects on A549 cells with an IC50 of 0.61μM.</p>Pureza:98%Cor e Forma:Odour Solidcis-Clovamide
CAS:<p>cis-Clovamide is a naturally occurring phenolic compound with noteworthy antioxidant, anti-inflammatory, and antiapoptotic properties.</p>Fórmula:C18H17NO7Cor e Forma:SolidPeso molecular:359.334SB-1295
<p>SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 μM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells.</p>Fórmula:C23H22ClNO6Pureza:98%Cor e Forma:SolidPeso molecular:443.88HC Toxin
CAS:<p>HC Toxin: cyclic tetrapeptide, reversible HDAC inhibitor (IC50=30 nM), upregulates 15-lipoxygenase-1, induces fetal hemoglobin, from C. carbonum.</p>Fórmula:C21H32N4O6Cor e Forma:SolidPeso molecular:436.509Bcl-2-IN-4
CAS:<p>Bcl-2-IN-4: potent, selective, oral Bcl-2 inhibitor with 1.5 nM IC50, >200x selectivity over Bcl-xL.</p>Fórmula:C46H50ClN9O7SCor e Forma:SolidPeso molecular:908.46HDAC3-IN-2
<p>HDAC3-IN-2 (compound 4i), a pyrazinyl hydrazide-based HDAC3 inhibitor with an IC50 of 14 nM, effectively targets triple-negative breast cancer cells.</p>Fórmula:C16H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:315.37dTAGV-1-NEG TFA
<p>dTAGV-1-NEG TFA, a diastereomer, serves as the heterobifunctional negative control for dTAGV-1. It acts specifically as an FKBP12 F36V-selective degrader [1].</p>Fórmula:C70H91F3N6O16SCor e Forma:SolidPeso molecular:1361.56PROTAC AR-NTD degrader 1
<p>PROTAC AR-NTD antagonist 1 (compound 18) is a small molecule belonging to the protein-targeting chimeras (PROTACs) that selectively targets the N-terminal</p>Fórmula:C41H47ClN6O7Pureza:98%Cor e Forma:SolidPeso molecular:771.3Thalidomide-PEG2-NH2
CAS:<p>Thalidomide-PEG2-NH2: synthetic E3 ligase ligand-linker, combines Thalidomide-based cereblon and PROTAC linker.</p>Fórmula:C17H19N3O6Cor e Forma:SolidPeso molecular:361.354AS-99 TFA
<p>AS-99 TFA: potent ASH1L inhibitor, IC50=0.79 μM, combats leukemia, inhibits cell growth, induces apoptosis.</p>Cor e Forma:SolidPhotosensitizer-3
CAS:<p>Photosensitizer-3, generates single-linear oxygen upon near-infrared light excitation in combination with FAP,potent and selective killing cancer cells.</p>Fórmula:C29H33ClI2N2O3Pureza:99.61%Cor e Forma:SolidPeso molecular:746.85LSD1-IN-36
LSD1-IN-36, an effective LSD1 inhibitor with an IC50 value of 0.8 nM, induces cell apoptosis and arrests the cell cycle. This compound also exhibits antitumor activity.Fórmula:C22H25N3O6SCor e Forma:SolidPeso molecular:459.52p38α inhibitor 6
<p>p38α inhibitor6 (compound 19) is a p38α inhibitor with an IC50 value of 0.68 μM. It induces apoptosis, arrests the cell cycle in the G0 and G2/M phases, reduces TNF-α concentration, upregulates the expression of the tumor suppressor gene p53, increases the Bax/BCL-2 ratio, and activates caspase3/7.</p>Cor e Forma:Odour SolidH3B-8800
CAS:<p>H3B-8800 is an SF3B1 modulator that can be used to study transfusion-dependent anemia.</p>Fórmula:C31H45N3O6Pureza:98.31%Cor e Forma:SoildPeso molecular:555.71EGFR-IN-153
<p>EGFR-IN-153 (Compound 5l) is an EGFR inhibitor that suppresses the proliferation of MDA-MB-231 cells with an IC50 of 0.73 μM and induces apoptosis. It is applicable for research in breast cancer.</p>Cor e Forma:Odour SolidRosomidnar
CAS:<p>PNT100: 24-base DNA oligo targeting BCL-2 regulatory region; halts tumor cell growth, induces death.</p>Fórmula:C227H291O141P23Cor e Forma:SolidPeso molecular:7220.63KP1019
CAS:<p>KP1019 is now discontinued.</p>Fórmula:C21H19Cl4N6RuCor e Forma:SolidPeso molecular:598.30eIF4A3-IN-7
CAS:<p>eIF4A3-IN-7: Potent eIF4A3 inhibitor, potential cancer/dysproliferation research (WO2019161345A1, Compound 8).</p>Fórmula:C26H25NO7Cor e Forma:SolidPeso molecular:463.486
