Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(127 produtos)
- FOXO1(3 produtos)
- IAP(65 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(24 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(91 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5622 produtos de "Apoptose"
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TAT-BH4 (Bcl-xL) (TFA)
<p>"TAT-BH4 (Bcl-xL) TFA, primarily localized at the mitochondria, inhibits apoptotic cell death.</p>Fórmula:C159H268N58O45·xC2HF3O2Pureza:98%Cor e Forma:SolidPeso molecular:3712.19 (free acid)WEE1-IN-7
<p>WEE1-IN-7 (compound 12h) is a potent, orally active WEE1 inhibitor with an IC50 value of 2.1 nM. This compound induces apoptosis and causes cell cycle arrest in the S phase, demonstrating antitumor activity.</p>Tyroserleutide hydrochloride
CAS:<p>Tyroserleutide HCl, a tripeptide from pig spleen, inhibits tumor growth in vivo/vitro.</p>Fórmula:C18H28ClN3O6Pureza:98%Cor e Forma:SolidPeso molecular:417.88ECDD-S16
ECDD-S16 is a potent inhibitor of pyroptosis. It effectively suppresses pyroptosis in Raw264.7 cells activated by surface and endosomal TLR ligands.Fórmula:C35H31FO12Peso molecular:662.17995HKB99
CAS:<p>HKB99 suppresses NSCLC growth, metastasis, and overcomes erlotinib resistance.</p>Fórmula:C23H18N2O6SPureza:97.35% - 97.35%Cor e Forma:SolidPeso molecular:450.46Urelumab
CAS:<p>"Urelumab (BMS-66513), a humanized IgG4 mAb CD137 agonist, boosts T-cell/NK cell-mediated cytotoxicity and anti-tumor activity."</p>Pureza:97.70%Cor e Forma:LiquidPeso molecular:145.90 kDaNecrosis inhibitor 2 (hydrocholide)
<p>Necrosis inhibitor 2 hydrochloride (Compound B19) is an agent that inhibits cellular necrosis. It is useful for researching diseases associated with necrotic pathways, including inflammation, cancer, metabolic disorders, and neurodegenerative diseases.</p>Fórmula:C24H26ClN5O5Peso molecular:499.16225Thalidomide-N-C3-O-C4-O-C3-OH
<p>Thalidomide-N-C3-O-C4-O-C3-OH is a conjugate of an E3 ligase ligand and a linker, used in the synthesis of the Aster-APROTAC degrader.</p>Fórmula:C23H31N3O7Peso molecular:461.2162RBN013209
CAS:<p>RBN013209 is a potent CD38 inhibitor. RBN013209 is useful in the treatment of cancer.</p>Fórmula:C19H24N6O3Pureza:99.84%Cor e Forma:SoildPeso molecular:384.43Chlopynostat
<p>Chlopynostat (Compound 6c) is an HDAC1 inhibitor with an IC50 value of 67 nM. It induces apoptosis by inhibiting HDAC1, thereby reversing STAT4/p66Shc defects.</p>Fórmula:C22H17ClN4O2Peso molecular:404.104Antitumor agent-113
<p>Antitumor Agent-113 exhibits cytotoxicity in A549 cells, with an IC50 of 46.60 μM, and induces apoptosis, making it applicable for research in non-small cell</p>Fórmula:C21H22ClN5O2SPureza:98%Cor e Forma:SolidPeso molecular:443.95Cu(I) chelator 1
<p>Cu(I) chelator 1 (Compound LH2) is a chelating agent specifically targeting the Cu(I) redox state. It inhibits the production of ROS.</p>Fórmula:C16H27NO4S3Peso molecular:393.11022rac-CCT-250863 HCl
<p>rac-CCT-250863 HCl: NEK 2 inhibitor, halts cell cycle, anti-cancer growth, boosts Pomalidomide-induced apoptosis.</p>Fórmula:C24H26ClF3N4O2SPureza:98.21%Cor e Forma:SoildPeso molecular:527P-gp inhibitor 16
<p>P-gp inhibitor 16 (compound 14) is an inhibitor of p-glycoprotein. It significantly enhances apoptosis induced by doxorubicin and displays anticancer properties.</p>Fórmula:C35H35N5O4Peso molecular:589.2689AVJ16
CAS:<p>AVJ16 as a member of the insulin growth factor 2 mRNA-binding protein family, binds to the mRNA of certain genes to regulate protein translation.</p>Fórmula:C28H27N3O4Pureza:98.87% - 99.72%Cor e Forma:SolidPeso molecular:469.53DC-Y13-27
<p>Dc-y13-27, a derivative of DC-Y13, is a potent YTHDF2 inhibitor (KD: 37.9 μM).</p>Fórmula:C14H10N2O2SPureza:99.75%Cor e Forma:SoildPeso molecular:270.31Hellebrin
CAS:<p>Cytotoxic and antiproliferative effects of Hellebrin on breast and lung cancer cells.</p>Fórmula:C36H52O15Cor e Forma:SolidPeso molecular:724.794-hydroperoxy cyclophosphamide
CAS:<p>4-hydroperoxy cyclophosphamide (4-OOH-CY) induces hepatotoxicity. It increases ghrelin levels and enhances inflammatory factors and oxidative markers.</p>Fórmula:C7H15Cl2N2O4PPureza:98%Cor e Forma:SolidPeso molecular:293.09Chloranil
CAS:<p>Chloranil (tetrachloro-p-benzoquinone) induces inflammation and neurological dysfunction and can be used to model inflammation in mice.</p>Fórmula:C6Cl4O2Pureza:99.38%Cor e Forma:SolidPeso molecular:245.88Z-DQMD-FMK
CAS:<p>Caspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.</p>Fórmula:C29H40FN5O11SPureza:98%Cor e Forma:SolidPeso molecular:685.72
