Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5593 produtos de "Apoptose"
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MDM2/XIAP-IN-2
CAS:<p>MDM2/XIAP-IN-2 is a dual inhibitor targeting murine double minute 2 (MDM2) and X-linked inhibitor of apoptosis protein (XIAP).</p>Fórmula:C29H32N2O4SCor e Forma:SolidPeso molecular:504.64A-385358
CAS:<p>A-385358 is a selective Bcl-xL inhibitor with Kis of 0.80 nM for Bcl-xL and 67 nM for Bcl-2, respectively.</p>Fórmula:C32H41N5O5S2Pureza:99.97%Cor e Forma:SolidPeso molecular:639.83MeOIstPyrd
CAS:<p>MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsic</p>Fórmula:C14H16N4O2SCor e Forma:SolidPeso molecular:304.37Apoptosis inducer 8
CAS:<p>Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be used</p>Fórmula:C29H22ClN5O2Cor e Forma:SolidPeso molecular:507.97HDAC-IN-42
CAS:<p>HDAC-IN-42, a potent HDAC inhibitor: IC50 - 0.19μM (HDAC1), 4.98μM (HDAC6); halts cancer cell growth, triggers apoptosis & G2/M arrest.</p>Fórmula:C20H15NO7Cor e Forma:SolidPeso molecular:381.34Butyrolactone I
CAS:<p>Butyrolactone I (Olomoucin) inhibits CDKs, blocks cdc2 kinases, and shows antitumor activity in lung and prostate cancers.</p>Fórmula:C24H24O7Pureza:98%Cor e Forma:SolidPeso molecular:424.44VEGFR-2-IN-22
CAS:<p>VEGFR-2-IN-22 blocks VEGFR-2/beta-tubulin, IC50=19.82 nM, induces apoptosis.</p>Fórmula:C26H24ClFN4O6Cor e Forma:SolidPeso molecular:542.94FAK-IN-5
CAS:<p>FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.</p>Fórmula:C29H29ClF3N3O4Cor e Forma:SolidPeso molecular:576.01NSC 107512
CAS:<p>NSC 107512, a sangivamycin-like molecule, inhibits CDK9, curbing myeloma growth and triggering cell death.</p>Fórmula:C12H16N6O5Cor e Forma:SolidPeso molecular:324.29JMX0293
<p>JMX0293, a salicylamide derivative, inhibits STAT3, inducing MDA-MB-231 cell apoptosis with IC50=3.38μM, while sparing MCF-10A (IC50>60μM).</p>Fórmula:C25H30Cl2N4O7Cor e Forma:SolidPeso molecular:569.43n-Octyl caffeate
CAS:<p>n-Octyl caffeate demonstrates anti-cancer and apoptosis-inducing properties in highly liver-metastatic murine colon 26-L5 carcinoma cell lines.</p>Fórmula:C17H24O4Cor e Forma:SolidPeso molecular:292.37CAY10682
CAS:<p>(±)-Nutlin-3 & CAY10682 inhibit p53-Mdm2; CAY also blocks NF-κB, IKKs phosphorylation, and cancer cell growth (IC50s = 2-6 μM).</p>Fórmula:C30H25BrFN5OCor e Forma:SolidPeso molecular:570.45RET-IN-16
CAS:<p>RET-IN-16: Selective RET inhibitor, IC50s 3.98-15.05 nM for various RET mutations; anticancer properties.</p>Fórmula:C31H29F3N8O2Cor e Forma:SolidPeso molecular:602.61Topoisomerase I inhibitor 2
CAS:<p>ZML-8 selectively inhibits Top1, blocks G2/M phase, causes DNA damage, and induces apoptosis with anti-tumor properties.</p>Fórmula:C18H15NO3Cor e Forma:SolidPeso molecular:293.32PDE5-IN-3
CAS:<p>PDE5-IN-3: Inhibits PDE5 (1.57 nM), EGFR (5.827 μM), Wnt pathway (1286.96 ng/mL), induces apoptosis, and has antitumor effects.</p>Fórmula:C21H14BrN5O2Cor e Forma:SolidPeso molecular:448.27D-Cl-amidine
CAS:<p>D-Cl-amidine is an effective and highly selective PAD1 inhibitor. D-Cl-amidine has a good correlation and no obvious toxicity.</p>Fórmula:C14H19ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:310.78PCAF-IN-2
CAS:<p>PCAF-IN-2 inhibits PCAF (IC50 = 5.31 µM), induces apoptosis, and halts G2/M cell cycle, showing anti-tumor properties.</p>Fórmula:C10H7F3N6Cor e Forma:SolidPeso molecular:268.2YH-306
CAS:<p>YH-306 (TRV055 acetate ) is a modulator of the FAK signaling pathway that acts by suppressing colorectal tumor growth and metastasis.</p>Fórmula:C19H18N2O2Pureza:98.06%Cor e Forma:SolidPeso molecular:306.36IDT
CAS:<p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>Fórmula:C8H5NS2Pureza:98%Cor e Forma:SolidPeso molecular:179.26CMLD010509
CAS:<p>CMLD010509 (SDS-1-021) inhibits oncogenic proteins MDM2, CCND1, MYC, MAF, MCL-1 in multiple myeloma.</p>Fórmula:C27H26BrNO7Pureza:98%Cor e Forma:SolidPeso molecular:556.4WK-298
CAS:<p>WK-298 is an effective MDM2/MDMX-p53 interaction inhibitor.</p>Fórmula:C35H38Cl2N6OPureza:98%Cor e Forma:SolidPeso molecular:629.62TNF-α-IN-1
CAS:<p>TNF-α-IN-1 is a TNF-α inhibitor.</p>Fórmula:C16H14ClN3O5Pureza:98.82%Cor e Forma:SolidPeso molecular:363.75CPI-7c
CAS:<p>CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.</p>Fórmula:C22H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:358.39Ivaltinostat
CAS:<p>CG-200745 is a potent inhibitor of HDAC. CG200745 induces apoptosis and also inhibits the deacetylation of histone H3 and tubulin.</p>Fórmula:C24H33N3O4Pureza:98%Cor e Forma:SolidPeso molecular:427.54NU-8165
CAS:<p>NU-8165 is an MDM2-p53 protein-protein interaction inhibitor.</p>Fórmula:C24H22ClNO3Pureza:98%Cor e Forma:SolidPeso molecular:407.89AK301
CAS:<p>AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM).</p>Fórmula:C19H21ClN2O2Pureza:99.27%Cor e Forma:SolidPeso molecular:344.84Gea 3162
CAS:<p>GEA 3162 blocks ADP-induced platelet clumping in PRP and boosts cGMP in granulocytes and leukocytes.</p>Fórmula:C7H4Cl2N4OPureza:98%Cor e Forma:SolidPeso molecular:231.04Antitumor agent-83
<p>Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.</p>Fórmula:C29H30N6O2Cor e Forma:SolidPeso molecular:494.59MEB55
CAS:<p>MEB55, an anticancer agent, acts by disrupting DNA repair and halting growth in prostate, colon, lung and breast cancer cells.</p>Fórmula:C22H17NO4SPureza:98%Cor e Forma:SolidPeso molecular:391.44MDM2-IN-1
CAS:<p>MDM2-IN-1 is a synthetic MDM2-p53 interaction (MDM2) inhibitor and contains the trans (D-)configuration.</p>Fórmula:C23H21Cl2FN2O3Cor e Forma:SolidPeso molecular:463.33Fomesafen
CAS:<p>Fomesafen (PP-021) is a diphenyl ether herbicide and an inhibitor of efficient and selective protoporphyrinogen IX oxidase (PPO).</p>Fórmula:C15H10ClF3N2O6SPureza:99.91% - 99.93%Cor e Forma:White Crystalline Solid Fomesafen Is A White Crystalline Solid Used As An HerbicidePeso molecular:438.76Tryptophanamide
CAS:<p>Tryptophanamide is a chymotrypsin inhibitor.</p>Fórmula:C11H13N3OPureza:98%Cor e Forma:SolidPeso molecular:203.24Dimethoate
CAS:<p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>Fórmula:C5H12NO3PS2Pureza:99.74% - 99.91%Cor e Forma:White Crystalline SolidPeso molecular:229.26Mitochonic Acid 35
CAS:<p>Mitochonic Acid 35 is a dual TNF-α and TGF-β1 inhibitor that acts by inhibiting IκB kinase phosphorylation and Smad3 phosphorylation.</p>Fórmula:C19H19NO5Pureza:98%Cor e Forma:SolidPeso molecular:341.36Mcl1-IN-9
CAS:<p>Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM.</p>Fórmula:C37H39ClN4O4Pureza:98%Cor e Forma:SolidPeso molecular:639.18MI-1061
CAS:<p>MI-1061 is a orally bioavailable inhibitor of MDM2 (MDM2-p53 interaction) (IC50=4.4 nM).</p>Fórmula:C30H26Cl2FN3O4Cor e Forma:SolidPeso molecular:582.45MG-115
CAS:<p>MG-115 inhibits 20S (21 nM Ki) and 26S (35 nM Ki) proteasomes, targets chymotrypsin-like activity & induces p53 apoptosis.</p>Fórmula:C25H39N3O5Pureza:97.12%Cor e Forma:White PowderPeso molecular:461.59RIP1 kinase inhibitor 6
CAS:<p>RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1</p>Fórmula:C19H18F2N2O3Pureza:98%Cor e Forma:SolidPeso molecular:360.35Filanesib
CAS:<p>Filanesib (ARRY 520) is a selective inhibitor of kinesin spindle protein (KSP, IC50 = 6 nM) with potent anti-proliferative activity.</p>Fórmula:C20H22F2N4O2SPureza:99.8%Cor e Forma:SolidPeso molecular:420.48AZM475271
CAS:<p>AZM475271 is a potent and selective inhibitor of Src kinase(IC50 : 5 nM)</p>Fórmula:C23H27ClN4O3Pureza:99.78%Cor e Forma:SolidPeso molecular:442.94ASK1-IN-3
CAS:<p>ASK1-IN-3, selective ASK1 inhibitor with 33.8 nM IC50; inhibits cell cycle kinases; induces apoptosis in HepG2 cells.</p>Fórmula:C18H18N8O2Cor e Forma:SolidPeso molecular:378.39Anticancer agent 57
CAS:<p>Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.</p>Fórmula:C20H21Cl2NO2Cor e Forma:SolidPeso molecular:378.29EGFR-IN-59
CAS:<p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>Fórmula:C27H23N5O4SCor e Forma:SolidPeso molecular:513.57Pim-1 kinase inhibitor 1
CAS:<p>Pim-1 kinase inhibitor 1, IC50 0.11 μM, combats various cancers by inducing apoptosis.</p>Fórmula:C19H13N3O3Cor e Forma:SolidPeso molecular:331.32Propiomazine
CAS:<p>Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.</p>Fórmula:C20H24N2OSPureza:98.5%Cor e Forma:SolidPeso molecular:340.48SMI-6860766
CAS:<p>SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.</p>Fórmula:C15H11BrClNOPureza:98%Cor e Forma:SolidPeso molecular:336.61E64FC26
CAS:<p>E64FC26 is a PDI family pan-inhibitor with antitumor activity that inhibits PDIA1 and PDIA6 and can be used to study multiple myeloma and pancreatic cancer.</p>Fórmula:C19H23F3O2Pureza:98.1% - 98.1%Cor e Forma:SolidPeso molecular:340.38CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Fórmula:C15H18ClNO3Cor e Forma:SolidPeso molecular:295.76SB-218078
CAS:<p>SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM).</p>Fórmula:C24H15N3O3Pureza:98%Cor e Forma:SolidPeso molecular:393.39Tubulin/HDAC-IN-1
CAS:<p>Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.</p>Fórmula:C21H18N4O3Cor e Forma:SolidPeso molecular:374.39Merck-22-6
CAS:<p>Merck-22-6 is an allosteric dual inhibitor of Akt1, Akt2.</p>Fórmula:C40H43N7O2Cor e Forma:SolidPeso molecular:653.82Antitumor agent-62
CAS:<p>Antitumor agent-62 releases NO, inhibits cancer cell growth, triggers apoptosis, and halts cell cycle at G2/M.</p>Fórmula:C21H19N3O9SCor e Forma:SolidPeso molecular:489.46BTK-IN-9
CAS:<p>BTK-IN-9 reversibly inhibits BTK, disrupts mitochondria, boosts ROS, and triggers apoptosis in Z138 cells, impeding condyloma cell growth.</p>Fórmula:C25H19N7O4Cor e Forma:SolidPeso molecular:481.46MMP-9-IN-4
CAS:<p>MMP-9-IN-4 inhibits MMP-9 (IC50=7.46nM) and AKT (IC50=8.82nM), induces apoptosis and is used in cancer research.</p>Fórmula:C28H19F3N4O6Cor e Forma:SolidPeso molecular:564.47RIPK1-IN-3
CAS:<p>RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.</p>Fórmula:C22H19F3N6O3Pureza:98%Cor e Forma:SolidPeso molecular:472.42EL-102
CAS:<p>EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.</p>Fórmula:C19H16N2O3S2Pureza:99.34%Cor e Forma:SolidPeso molecular:384.47(E)-[6]-Dehydroparadol
CAS:<p>(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.</p>Fórmula:C17H24O3Pureza:99.85%Cor e Forma:SolidPeso molecular:276.37Antitumor agent-70
CAS:<p>Antitumor agent-70, a potent c-Kit kinase inhibitor, induces apoptosis with an IC50 of 0.12 μM, showing promise as a cancer therapy.</p>Fórmula:C21H18N4O2Cor e Forma:SolidPeso molecular:358.39Selicrelumab
CAS:<p>Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.</p>Pureza:98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Cor e Forma:LiquidW146 TFA
CAS:<p>W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.</p>Fórmula:C18H28F3N2O6PCor e Forma:SolidPeso molecular:456.399MYRA-A
CAS:<p>MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.</p>Fórmula:C19H20N2O4Pureza:98%Cor e Forma:SolidPeso molecular:340.37CK2/ERK8-IN-1
CAS:<p>TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.</p>Fórmula:C11H9Br4N3O2Pureza:98.22%Cor e Forma:SolidPeso molecular:534.82MBM-17
CAS:<p>MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).</p>Fórmula:C28H28N6O2Pureza:98%Cor e Forma:SolidPeso molecular:480.56(R)-STU104
CAS:<p>(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.</p>Fórmula:C18H18O4Pureza:98.91% - 99.42%Cor e Forma:SolidPeso molecular:298.33IV-23
CAS:<p>IV-23 hinders cell growth, blocks M phase, induces apoptosis, and shows promise as an anticancer agent.</p>Fórmula:C18H18BrNO4Pureza:98%Cor e Forma:SolidPeso molecular:392.24KY1022
CAS:<p>KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.</p>Fórmula:C17H19N3OSCor e Forma:SolidPeso molecular:313.42L6H21
CAS:<p>L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.</p>Fórmula:C18H18O4Pureza:99.26%Cor e Forma:SolidPeso molecular:298.33GL-331
CAS:<p>GL-331, a DNA topoisomerase II inhibitor, is used potentially for the treatment of small cell lung cancer and gastric cancer.</p>Fórmula:C27H24N2O9Cor e Forma:SolidPeso molecular:520.49SD-36
CAS:<p>SD-36: Potent, selective PROTAC STAT3 degrader, Kd ~50 nM, effective on mutants, IC50=10 nM, strong anti-tumor effects, enables mouse tumor regression.</p>Fórmula:C59H62F2N9O12PPureza:98% - >99.99%Cor e Forma:SoildPeso molecular:1158.15RSH-7
CAS:<p>RSH-7 is a potent dual inhibitor of BTK and FLT3, with IC50s of 47 and 12 nM, respectively.RSH-7 has antiproliferative and antitumor activities, inducing</p>Fórmula:C22H25FN8OPureza:98.31%Cor e Forma:SolidPeso molecular:436.493-ATA
CAS:<p>3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons.</p>Fórmula:C13H10N2SCor e Forma:SolidPeso molecular:226.3EC359
CAS:<p>EC359 is a Leukemia Inhibitory Factor Receptor (LIFR) inhibitor with anticancer activity for the study of leukemia and endometrial cancer.</p>Fórmula:C36H38F2O2Pureza:98.11% - 98.11%Cor e Forma:SolidPeso molecular:540.68Simmiparib
CAS:<p>Simmiparib (SMOCL-9112) is a PARP1 and PARP2 inhibitor that promotes apoptosis.Simmiparib is used to study Parkinson's disease and melanoma.</p>Fórmula:C23H18F4N6O2Pureza:99.05% - 99.51%Cor e Forma:SolidPeso molecular:486.42Tubulin polymerization-IN-31
CAS:<p>Compound 4c, inhibits tubulin polymerization, IC50 3.64 μM, and induces cancer cell apoptosis.</p>Fórmula:C18H13ClFN3Cor e Forma:SolidPeso molecular:325.77CCCI-01
CAS:<p>CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.</p>Fórmula:C11H9N3O4Pureza:>99.99%Cor e Forma:SolidPeso molecular:247.213-(3-Phenoxybenzyl)amino-β-carboline
CAS:<p>3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers.</p>Fórmula:C24H19N3OCor e Forma:SolidPeso molecular:365.43EGFR-IN-56
CAS:<p>EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.</p>Fórmula:C23H22N4O3SCor e Forma:SolidPeso molecular:434.51ACA-28
CAS:<p>ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.</p>Fórmula:C17H16O6Pureza:98.73%Cor e Forma:SolidPeso molecular:316.31Fenoldopam hydrochloride
CAS:<p>Fenoldopam HCl: D1 dopamine receptor agonist, vasodilator, doesn't cross blood-brain barrier, α2-adrenoceptor antagonist.</p>Fórmula:C16H17Cl2NO3Cor e Forma:SolidPeso molecular:342.22SKI-I
CAS:<p>SKI-I: Human sphingosine kinase inhibitor, IC50 1.2μM; hERK2 inhibitor, IC50 11μM; promotes tumor cell apoptosis.</p>Fórmula:C25H18N4O2Cor e Forma:SolidPeso molecular:406.44SID 3712249
CAS:<p>SID 3712249 is an inhibitor of the biogenesis of microRNA-544 (miR-544).</p>Fórmula:C17H21N7Pureza:98%Cor e Forma:SolidPeso molecular:323.4iMAC2
CAS:<p>iMAC2, a potent MAC (Membrane Attack Complex) inhibitor, exhibits an IC50 of 28 nM and an LD50 of 15,000 nM, demonstrating significant efficacy in inhibiting</p>Fórmula:C19H20Br2FN3Cor e Forma:SolidPeso molecular:469.19Epinephrine bitartrate
CAS:<p>L-Epinephrine Bitartrate is alpha- and beta-adrenergic receptor stimulator.</p>Fórmula:C13H19NO9Pureza:98.6% - 99.07%Cor e Forma:White SolidPeso molecular:333.3Ormeloxifene
CAS:estrogen receptor modulatorFórmula:C30H35NO3Pureza:98%Cor e Forma:SolidPeso molecular:457.6ADU-S100
CAS:<p>ADU-S100 (MIW815) is a STING agonist that significantly induces the production of IFN-β,TNF-α,IL-6,and MCP-1,induces TBK1 and IRF3 phosphorylation,antitumour.</p>Fórmula:C20H24N10O10P2S2Pureza:99.83%Cor e Forma:SolidPeso molecular:690.54NMK-TD-100
CAS:<p>NMK-TD-100: Microtubule disruptor, anti-proliferative, blocks mitosis, causes apoptosis in HeLa; IC50=17.5µM for tubulin polymerization.</p>Fórmula:C19H17N3O3SPureza:98%Cor e Forma:SolidPeso molecular:367.42VEGFR-2/BRAF-IN-1
<p>VEGFR-2/BRAF-IN-1 inhibits VEGFR-2, BRAF V600E & BRAF WT with IC50 of 49, 63 and 5 nM, triggers apoptosis, and halts G1/S cell cycle.</p>Fórmula:C26H20Cl2F3N5O3S2Cor e Forma:SolidPeso molecular:642.5BS-181
CAS:<p>BS-181 is a highly selective CDK7 inhibitor (IC50: 21 nM); >40-fold selective for CDK7 than CDK1/2/4/5/6/9.</p>Fórmula:C22H32N6Pureza:98%Cor e Forma:SolidPeso molecular:380.53MPT0B392
CAS:<p>MPT0B392 is an orally active quinoline derivative, induces c-Jun N-terminal kinase (JNK) activation.</p>Fórmula:C19H20N2O6SCor e Forma:SolidPeso molecular:404.44AKCI
CAS:<p>AKCI is a PPI inhibitor that acts by targeting the AURKC-IκBα interaction.</p>Fórmula:C19H27N7OPureza:98%Cor e Forma:SolidPeso molecular:369.46CMLD012612
CAS:<p>CMLD012612 is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. It inhibits cell translation and is cytotoxic to NIH/3T3 cells (IC50: 2 nM).</p>Fórmula:C31H33N3O7Pureza:98%Cor e Forma:SolidPeso molecular:559.61Quinidine Monosulfate
CAS:<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Fórmula:C40H50N4O8SCor e Forma:SolidPeso molecular:746.92Anticancer agent 67
CAS:<p>Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.</p>Fórmula:C26H24F2N6O2S2Cor e Forma:SolidPeso molecular:554.63RGB-286147
CAS:<p>RGB-286147 is a potent, selective, ATP-competitive Cdks inhibitor.</p>Fórmula:C23H22Cl2N4O3Pureza:98%Cor e Forma:SolidPeso molecular:473.35(R)-eIF4A3-IN-2
CAS:<p>(R)-eIF4A3-IN-2, a weaker eIF4A3-IN-2 isomer, inhibits eIF4A3 selectively with 110 nM IC50.</p>Fórmula:C25H19Br2ClN4O2Cor e Forma:SolidPeso molecular:602.71Caspase-3/7 activator 3
<p>Caspase-3/7 activator 3 triggers apoptosis with tumor selectivity and anti-proliferative effects.</p>Fórmula:C24H27NO5Cor e Forma:SolidPeso molecular:409.47Anticancer agent 63
CAS:<p>Compound 3h fights various cancers; most effective on MCF-7 (IC50 3.4 μM). Triggers apoptosis; alters Bcl-2, IL-2, Caspase-3 levels, has antioxidant effects.</p>Fórmula:C17H24F3NOSeCor e Forma:SolidPeso molecular:394.33Lexibulin dihydrochloride
CAS:<p>Lexibulin 2HCl inhibits tubulin polymerization (IC50: 10-100 nM) and shows potent anti-cancer cytotoxicity and vascular disruption in vitro/vivo.</p>Fórmula:C24H32Cl2N6O2Pureza:98%Cor e Forma:SolidPeso molecular:507.46Tubulin inhibitor 30
CAS:<p>Tubulin Inhibitor 30, exhibiting an IC50 value of 0.52 μM, functions as an inhibitor of tubulin assembly. Additionally, it can induce ferroptosis.</p>Fórmula:C22H19N3O5Cor e Forma:SolidPeso molecular:405.4S116836
CAS:<p>S116836 is a tyrosine kinase inhibitor.</p>Fórmula:C27H21F3N6OPureza:98%Cor e Forma:SolidPeso molecular:502.49PD1-PDL1-IN 1
CAS:<p>PD1-PDL1-IN 1 is a potent inhibitor of programmed cell death 1 (PD-1),and used as immune modulator.</p>Fórmula:C14H23N7O6Pureza:98%Cor e Forma:SolidPeso molecular:385.38CDK9-IN-18
CAS:<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Fórmula:C27H20N8OCor e Forma:SolidPeso molecular:472.5BRD0476
CAS:<p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.</p>Fórmula:C35H38N4O8SPureza:98%Cor e Forma:SolidPeso molecular:674.76CDK6/PIM1-IN-1
CAS:<p>CDK6/PIM1-IN-1: A dual inhibitor for CDK6 (39 nM IC50) & PIM1 (88 nM), also targets CDK4 (3.6 nM IC50), halts AML cell growth, and induces apoptosis.</p>Fórmula:C25H28FN9Cor e Forma:SolidPeso molecular:473.55CB-64D
CAS:<p>CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.</p>Fórmula:C22H23NO2Cor e Forma:SolidPeso molecular:333.42MBM-17S
CAS:<p>MBM-17S, a potent NIMA-related kinase 2 (Nek2) inhibitor with an IC50 of 3 nM, effectively inhibits cancer cell proliferation by inducing cell cycle arrest and</p>Fórmula:C36H40N6O10Pureza:98%Cor e Forma:SolidPeso molecular:716.74PI3K-IN-34
CAS:<p>PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.</p>Fórmula:C23H22N6O3Cor e Forma:SolidPeso molecular:430.46Isodispar B
CAS:<p>Isodispar B: an anticancer drug, halts many cancer types' growth, triggers cell death.</p>Fórmula:C20H18O5Cor e Forma:SolidPeso molecular:338.35NBI-42902
CAS:<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Fórmula:C27H24F3N3O3Cor e Forma:SolidPeso molecular:495.49PD-1-IN-18
CAS:<p>PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.</p>Fórmula:C11H17N5O8Pureza:98%Cor e Forma:SolidPeso molecular:347.28Anticancer agent 76
CAS:<p>Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.</p>Fórmula:C32H33NO5SCor e Forma:SolidPeso molecular:543.67Apogossypolone (ApoG2)
CAS:<p>Apogossypolone (ApoG2) is a semi-synthesized derivative of gossypol which is a nonpeptidic small molecule inhibitor targeting Bcl-2 family proteins with K i</p>Fórmula:C28H26O8Cor e Forma:SolidPeso molecular:490.5PARP1/BRD4-IN-1
CAS:<p>PARP1/BRD4-IN-1 selectively inhibits PARP1 (49 nM IC50) and BRD4 (202 nM IC50), hindering pancreatic cancer cell growth.</p>Fórmula:C29H26N6O3Cor e Forma:SolidPeso molecular:506.56PERK-IN-5
CAS:<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5ARN 14494
CAS:<p>ARN 14494, a potent SPT inhibitor (IC50=27.3 nM), reduces ceramide synthesis and neuroinflammation, and protects against β-amyloid toxicity.</p>Fórmula:C24H32N4O3Cor e Forma:SolidPeso molecular:424.54PHM16
CAS:<p>PHM16 is an ATP competitive FAK and FGFR2 inhibitor.</p>Fórmula:C20H22N6O4Pureza:98%Cor e Forma:SolidPeso molecular:410.43CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Fórmula:C14H15NO4Pureza:98%Cor e Forma:SolidPeso molecular:261.27Antiproliferative agent-11
<p>Antiproliferative agent-11, a Ruthenium(II) complex, targets multiple cancers with IC50s of 6-10 μM.</p>Fórmula:C31H34Cl2N6O3P2RuCor e Forma:SolidPeso molecular:772.56AQX-016A
CAS:<p>AQX-016A, a potent SHIP1 agonist, is an oral analog of pelorol, 3x stronger, inhibits PI3K, TNFa, for inflammation research.</p>Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.49HIOC
CAS:<p>TrkB agonist; shields neurons & retinas; crosses blood-brain & retinal barriers.</p>Fórmula:C16H19N3O3Cor e Forma:SolidPeso molecular:301.34Berubicin HCl
CAS:<p>Berubicin hydrochloride, a brain-penetrating anthracycline, disrupts DNA replication and repair by inhibiting topoisomerase II.</p>Fórmula:C34H36ClNO11Cor e Forma:SolidPeso molecular:670.1Bcl-2/Mcl-1-IN-3
CAS:<p>Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.</p>Fórmula:C27H26ClNO4Cor e Forma:SolidPeso molecular:463.95GGTI-2154
CAS:<p>GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity against</p>Fórmula:C24H28N4O3Cor e Forma:SolidPeso molecular:420.5CCT128930
CAS:<p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>Fórmula:C18H20ClN5Pureza:99.07% - 99.18%Cor e Forma:SolidPeso molecular:341.84CDK/HDAC-IN-2
CAS:<p>CDK/HDAC-IN-2 inhibits HDAC1,2,3, CDK1,2, induces G2/M arrest, apoptosis, and shows anti-tumor effects.</p>Fórmula:C25H20Cl2N6O3Cor e Forma:SolidPeso molecular:523.37TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Fórmula:C20H21N5OSCor e Forma:SolidPeso molecular:379.48Casein Kinase inhibitor A51
CAS:<p>Casein Kinase inhibitor A51 is a CK1α inhibitor with anticancer activity used in the study of breast and prostate cancer.</p>Fórmula:C18H25ClN6Pureza:99.88%Cor e Forma:SolidPeso molecular:360.88NSC114792
CAS:<p>NSC114792 is a selective JAK3 inhibitor.</p>Fórmula:C26H32N4O2SPureza:98%Cor e Forma:SolidPeso molecular:464.62Antiproliferative agent-7
CAS:<p>Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.</p>Fórmula:C28H32N4OCor e Forma:SolidPeso molecular:440.58S-Gem
CAS:<p>S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.</p>Fórmula:C13H15F2N3O6S2Pureza:98%Cor e Forma:SolidPeso molecular:411.4p-nitro-Pifithrin-α
CAS:<p>p-nitro-Pifithrin-α is a cell-permeable analog of pifithrin-α, a potent p53 inhibitor.</p>Fórmula:C15H16BrN3O3SCor e Forma:SolidPeso molecular:398.27DMH2
CAS:<p>DMH2 is an antagonist of bone morphogenetic protein (BMP) type I receptor. It acts by decreasing growth and inducing cell death of lung cancer cell lines.</p>Fórmula:C27H25N5O2Pureza:98%Cor e Forma:SolidPeso molecular:451.52Topoisomerase II inhibitor 10
CAS:<p>Topoisomerase II inhibitor 10 is a potent inhibitor of topoisomerase II (IC50: 7.45 μM).</p>Fórmula:C27H20N6O7SCor e Forma:SolidPeso molecular:572.55Alteminostat
CAS:<p>Alteminostat is used as a histone deacetylase inhibitor and is an antineoplastic drug candidate.</p>Fórmula:C27H36N6O3Cor e Forma:SolidPeso molecular:492.61HLI98C
CAS:<p>HLI98C is a HDM2 ubiquitin ligase inhibitor with anti-tumor activity.</p>Fórmula:C17H9ClN4O4Cor e Forma:SolidPeso molecular:368.73Cl-amidine
CAS:<p>Cl-amidine, an oral PAD inhibitor (IC50: 0.8-6.2 μM for PAD1/3/4), induces apoptosis in cancer cells.</p>Fórmula:C14H19ClN4O2Pureza:98%Cor e Forma:SolidPeso molecular:310.78Quinidine polygalacturonate
CAS:<p>Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.</p>Fórmula:C26H34N2O9Cor e Forma:SolidPeso molecular:518.22643Caylin-2
CAS:<p>Nutlin-3 activates p53 by blocking MDM2. Caylin-2, a nutlin-3 analog with trifluoromethyl instead of chlorine, is 10x less potent with an 8 μM IC50.</p>Fórmula:C32H30F6N4O4Cor e Forma:SolidPeso molecular:648.6MMP2-IN-1
CAS:<p>MMP2-IN-1, an MMP2 inhibitor (IC50 = 6.8μM), halts growth and induces apoptosis in some cancers.</p>Fórmula:C15H13NO5SCor e Forma:SolidPeso molecular:319.33p53 Activator 5
CAS:<p>Potent p53 Activator 5, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Fórmula:C29H32F6N4OCor e Forma:SolidPeso molecular:566.58NVX-207
CAS:<p>NVX-207 is a derivative of betulinic acid. It has anti-cancer activity.</p>Fórmula:C36H59NO6Pureza:98%Cor e Forma:SolidPeso molecular:601.86PI3K inhibitor C 96
CAS:<p>PI3K inhibitor C 96 is an inhibitor of phosphatidylinositol 3-kinase. It shows effective activity against multiple myeloma in vitro and in vivo.</p>Fórmula:C11H8N2O3SPureza:98%Cor e Forma:SolidPeso molecular:248.26PD173952
CAS:<p>PD173952 is a Src kinase and Myt1 inhibitor with antitumor activity, inhibits Lyn, Abl and Csk, and induces Bcr-Abl-dependent hematopoietic cell apoptosis.</p>Fórmula:C24H21Cl2N5O2Pureza:99.5%Cor e Forma:SolidPeso molecular:482.36ATX inhibitor 13
CAS:<p>ATX inhibitor 13: orally active, IC50 3.4 nM, halts RAW264.7 cells at G2, curbs growth/migration, prompts apoptosis, suppresses tumors.</p>Fórmula:C31H35Cl2N5O3Cor e Forma:SolidPeso molecular:596.55Topoisomerase II inhibitor 7
CAS:<p>Topoisomerase II inhibitor 7 halts cell division and induces apoptosis, targeting topoisomerase II alpha with a 3.19 μM IC50.</p>Fórmula:C32H28BrN5O5SCor e Forma:SolidPeso molecular:674.56QTX125
CAS:<p>QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.</p>Fórmula:C23H19N3O5Cor e Forma:SolidPeso molecular:417.41K145
CAS:<p>K145: Selective, oral SphK2 inhibitor, IC50 4.3 μM, Ki 6.4 μM, promotes cell apoptosis, strong antitumor effect, inactive against SphK1/other kinases.</p>Fórmula:C18H24N2O3SPureza:98%Cor e Forma:SolidPeso molecular:348.46Nampt-IN-8
CAS:<p>Nampt-IN-8 is a NAMPT inhibitor (IC50: 0.183 μM) and a good substrate for NQO1. Nampt-IN-8 induces reactive oxygen species (ROS) production and apoptosis.</p>Fórmula:C36H35N3O4Cor e Forma:SolidPeso molecular:573.68MR2938
CAS:<p>MR2938: AChE inhibitor (IC50=5.04μM), reduces NO (IC50=3.29μM), blocks MAPK/JNK, NF-κB; for AD research.</p>Fórmula:C21H24N4O3Cor e Forma:SolidPeso molecular:380.44AMPK activator 11
CAS:<p>AMPK Activator 11 is a nanomolar potent inhibitor of cell proliferation in various colorectal carcinomas (CRCs), acting through the selective activation of AMP-</p>Fórmula:C25H20N4O2Pureza:98%Cor e Forma:SolidPeso molecular:408.45VEGFR-2-IN-23
CAS:<p>VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.</p>Fórmula:C22H15N5O2Cor e Forma:SolidPeso molecular:381.39GLS1 Inhibitor-4
CAS:<p>GLS1 Inhibitor-4 (41e) has 11.86 nM IC50, strong binding, disrupts glutamine metabolism, induces apoptosis, and shows antitumor effects.</p>Fórmula:C29H27F3N10O2S2Pureza:98%Cor e Forma:SolidPeso molecular:668.72PDPOB
CAS:<p>PDPOB, a phenyl carboxylic acid derivative, may protect neurons from ischemic damage by reducing mitochondrial issues, oxidative stress, and cell death.</p>Fórmula:C15H20O5Cor e Forma:SolidPeso molecular:280.32HI5
CAS:<p>HI5: potent tubulin/IDO inhibitor, IC50 70 nM (HeLa), blocks kynurenine, G2/M arrest, spurs T cell activity, & triggers apoptosis.</p>Fórmula:C42H43N5O8Cor e Forma:SolidPeso molecular:745.82WJ35435
CAS:<p>WJ35435 is a histone deacetylase and topoisomerase I dual inhibitor.</p>Fórmula:C20H21N3O3Pureza:98%Cor e Forma:SolidPeso molecular:351.4HDAC-IN-51
<p>HDAC-IN-51 is an HDAC inhibitor.</p>Fórmula:C27H24N4O2Pureza:97.19%Cor e Forma:SolidPeso molecular:436.51MX107
CAS:<p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>Fórmula:C24H28N2O2Cor e Forma:SolidPeso molecular:376.49αβ-Tubulin-IN-1
CAS:<p>αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.</p>Fórmula:C25H19N3O3Cor e Forma:SolidPeso molecular:409.44ZMF-10
CAS:<p>ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.</p>Fórmula:C19H17F6N7OCor e Forma:SolidPeso molecular:473.38MMP-9-IN-3
CAS:<p>MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.</p>Fórmula:C29H25N3O4Cor e Forma:SolidPeso molecular:479.53Darinaparsin
CAS:<p>Darinaparsin, a dimethylated arsenic-glutathione compound, is cytotoxic to various cancer cells with diverse IC50 values and inhibits tumor growth in mice.</p>Fórmula:C12H22AsN3O6SCor e Forma:SolidPeso molecular:411.31Rohinitib
CAS:<p>Rohinitib, an eIF4A inhibitor, triggers apoptosis in AML cells and lessens tumor load in models.</p>Fórmula:C29H31NO8Cor e Forma:SolidPeso molecular:521.56SCAL-255
CAS:<p>SCAL-255 is a mitochondrial complex I (CI) inhibitor, exhibiting potent inhibition with an IC50 of 1.14 μM.</p>Fórmula:C27H28F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:527.54ANO1-IN-3
CAS:<p>ANO1-IN-3 (Compound 3n) can induces apoptosis that is a potent and selective inhibitor of ANO1 with an IC 50 of 1.23 μM [1].</p>Fórmula:C20H17NO3Cor e Forma:SolidPeso molecular:319.35CAY10773
CAS:<p>CAY10773, a sorafenib derivative, inhibits cancer cells over non-cancerous ones and induces apoptosis or ferroptosis in T24 cells.</p>Fórmula:C22H17Cl2N5OCor e Forma:SolidPeso molecular:438.31TNF-α-IN-10
CAS:<p>TNF-α-IN-10 (compound 8a) acts as an inhibitor of IL-6 and TNF-α, demonstrating anti-inflammatory activity [1].</p>Fórmula:C17H14O4Cor e Forma:SolidPeso molecular:282.29FD223
CAS:<p>FD223, a PI3Kδ inhibitor, is highly potent (IC50=1 nM) and selective, limiting AML cell growth by causing G1 arrest.</p>Fórmula:C17H12ClN5O2SCor e Forma:SolidPeso molecular:385.83SEC
CAS:<p>SEC triggers ANXA7 GTPase via AMPK/mTORC1/STAT3, causing ITGB4-driven apoptosis in ITGB4-high cancer cells.</p>Fórmula:C22H23ClN2O5Cor e Forma:SolidPeso molecular:430.88Metaproterenol
CAS:<p>Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).</p>Fórmula:C11H17NO3Pureza:98%Cor e Forma:SolidPeso molecular:211.26EGFR/BRAFV600E-IN-1
CAS:<p>EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).</p>Fórmula:C24H24ClN3O3Cor e Forma:SolidPeso molecular:437.92MDM2/XIAP-IN-3
CAS:<p>MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing</p>Fórmula:C29H30N2O5SCor e Forma:SolidPeso molecular:518.62DNA topoisomerase II inhibitor 1
CAS:<p>Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.</p>Fórmula:C28H24N4O3SCor e Forma:SolidPeso molecular:496.58CS1
CAS:<p>CS1: potent topoisomerase II alpha inhibitor, broad-spectrum antitumor, low toxicity, anti-resistance, induces DNA damage, G2/M arrest, apoptosis.</p>Fórmula:C16H12O3Cor e Forma:SolidPeso molecular:252.26Antitumor agent-55
CAS:<p>Antitumor agent-55 (5q) inhibits PC3 (IC50: 0.91 μM), blocks G1/S phase, induces apoptosis, and halts migration.</p>Fórmula:C32H34N6O4SCor e Forma:SolidPeso molecular:598.72(rel)-Oxaliplatin
CAS:<p>(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.</p>Fórmula:C8H14N2O4PtCor e Forma:SolidPeso molecular:397.29YM-155 hydrochloride
CAS:<p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>Fórmula:C20H19ClN4O3Cor e Forma:SolidPeso molecular:398.85Anti-inflammatory agent 15
CAS:<p>Compound 29, anti-inflammatory and antimycobacterial, halts Mtb H37Rv and M299 growth; MIC50 at 2.3 and 7.8 μM. Blocks iNOS, TNF-α, IL-1β.</p>Fórmula:C17H20N2SCor e Forma:SolidPeso molecular:284.42PDMP (hydrochloride)
CAS:<p>PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.</p>Fórmula:C23H39ClN2O3Cor e Forma:SolidPeso molecular:427.03NSC260594
CAS:<p>NSC260594 is a chemical compound that promotes apoptosis by binding to the shallow groove of the Mcl-1 protein and suppressing its expression through down-</p>Fórmula:C29H24N6O3Cor e Forma:SolidPeso molecular:504.54GY1-22
CAS:<p>GY1-22, an inhibitor targeting the DNAJA1-mutP53 R175H interaction pocket, holds potential for cancer research applications.</p>Fórmula:C23H20N4OSCor e Forma:SolidPeso molecular:400.5KRC-108
CAS:<p>KRC-108 is a potent kinase inhibitor targeting Ron, Flt3, TrkA, and c-Met with strong anti-proliferative effects on various cancer cells.</p>Fórmula:C20H20N6OCor e Forma:SolidPeso molecular:360.41Apoptotic agent-1
CAS:<p>Compound 8a is an apoptotic agent that boosts Fas receptor and Cyto C genes to fight cancer with low toxicity.</p>Fórmula:C12H6ClN5O2SCor e Forma:SolidPeso molecular:319.73(S)-Elobixibat
CAS:<p>(S)-Elobixibat is the S-isomer of Elobixibat. It is an orally active inhibitor of Apical Sodium-Dependent Bile (IBAT) and can reduce LDL cholesterol, increase serum GLP-1, and promote colonic motility. This compound shows potential for treating metabolic syndrome and can be studied for constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors.</p>Fórmula:C36H45N3O7S2Cor e Forma:SolidPeso molecular:695.89Anticancer agent 66
CAS:<p>Anticancer agent 66, a ciprofloxacin analog, triggers apoptosis in MCF-7 cells.</p>Fórmula:C26H23Cl2FN6O2S2Cor e Forma:SolidPeso molecular:605.53Antitumor agent-44
CAS:<p>Antitumor agent-44 (Compound 5n) elicits potent antitumor effects by inducing disruption of mitochondrial homeostasis, cell cycle arrest, and apoptosis in human</p>Fórmula:C24H15N3O3Cor e Forma:SolidPeso molecular:393.39BR102375
CAS:<p>BR102375 is a non-TZD PPAR γ full agonist (EC50: 0.28 μM) for the treatment of type 2 diabetes.</p>Fórmula:C31H34N6O4Pureza:98%Cor e Forma:SolidPeso molecular:554.64GRI977143
CAS:<p>GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.</p>Fórmula:C22H17NO4SPureza:98.07%Cor e Forma:SolidPeso molecular:391.44W1131
CAS:<p>W1131 is a potent STAT3 inhibitor and ferroptosis trigger, reducing cancer progression and 5-FU resistance.</p>Fórmula:C23H19N5O4Cor e Forma:SolidPeso molecular:429.43LLL3
CAS:<p>LLL3 is a small molecule STAT3 inhibitor.</p>Fórmula:C16H10O4Cor e Forma:SolidPeso molecular:266.25DRI-C21041
CAS:<p>DRI-C21041 is a potent inhibitor of the CD40/CD40L interaction, demonstrating an inhibitory concentration 50 (IC50) value of 0.31 μM.</p>Fórmula:C30H21N3O7SCor e Forma:SolidPeso molecular:567.57DRI-C25441
CAS:<p>DRI-C25441 is a potent inhibitor of the CD40-CD40L interaction, exhibiting an IC50 value of 0.36 μM, and is capable of suppressing the immune response triggered</p>Fórmula:C31H21N3O6Cor e Forma:SolidPeso molecular:531.51CFM 4
CAS:CFM 4 is a potent small molecule CARP-1/APC-2 antagonist that prevents CARP-1 from binding to APC-2, contributes to G2M cell cycle arrest, and induces apoptosisFórmula:C22H16ClN3OSPureza:98.16%Cor e Forma:SolidPeso molecular:405.9Semapimod
CAS:<p>Semapimod is an inhibitor of proinflammatory cytokine production, capable of suppressing TNF-α, IL-1β, and IL-6.</p>Fórmula:C34H52N18O2Cor e Forma:SolidPeso molecular:744.9BRD4 Inhibitor-15
CAS:<p>BRD4 Inhibitor-15 targets BRD4 with 18 nM IC50, induces apoptosis in 22RV1 cells, and lowers c-Myc, aiding prostate cancer research.</p>Fórmula:C22H21N3O2Cor e Forma:SolidPeso molecular:359.42LG190178
CAS:<p>LG190178, a vitamin D receptor (VDR) ligand, is a therapeutic agent used for the treatment of psoriasis, osteoporosis, and secondary hyperparathyroidism.</p>Fórmula:C28H42O5Cor e Forma:SolidPeso molecular:458.63PDE5/HDAC-IN-1
CAS:<p>PDE5/HDAC-IN-1 is a potent inhibitor of phosphodiesterase 5 (PDE5) and HDAC, with IC50 values of 46.3 nM and 14.5 nM, respectively.</p>Fórmula:C27H29BrN4O4Cor e Forma:SolidPeso molecular:553.45Apoptosis inducer 6
CAS:<p>Apoptosis inducer 6 is an anticancer agent with broad-spectrum anticancer activity that induces apoptosis, which triggers cell death.</p>Fórmula:C27H26N4O3SCor e Forma:SolidPeso molecular:486.59ATAD2-IN-1
CAS:<p>ATAD2-IN-1 (compound 19f) serves as a potent ATAD2 inhibitor (IC 50: 0.27 μM), capable of inducing apoptosis. Additionally, it suppresses c-Myc activation and impedes the migration of BT-549 cells [1].</p>Fórmula:C22H26N6O5Cor e Forma:SolidPeso molecular:454.48VU0285655-1
CAS:<p>VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.</p>Fórmula:C25H27N5O2Pureza:99.73%Cor e Forma:SolidPeso molecular:429.51
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