Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Bax activator-1
CAS:<p>Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].</p>Fórmula:C29H36N4O3Cor e Forma:SolidPeso molecular:488.62NVS-CECR2-1
CAS:<p>NVS-CECR2-1 is a CECR2 inhibitor with anti-tumor activity that inhibits chromatin binding of the CECR2 BRD.</p>Fórmula:C27H37N5O2SPureza:98.68%Cor e Forma:SolidPeso molecular:495.68Propiomazine
CAS:<p>Propiomazine is an orally active antihistamine compound with sedative properties, useful for controlling insomnia in neurological disorders.</p>Fórmula:C20H24N2OSPureza:98.5%Cor e Forma:SolidPeso molecular:340.48BIM-46174
CAS:<p>BIM-46174 has anticancer activity, inhibits the growth of a large number of human cancer cell lines, and induces caspase-3-dependent cancer cell apoptosis.</p>Fórmula:C22H30N4OSCor e Forma:SolidPeso molecular:398.57STAT3-IN-11
CAS:<p>STAT3-IN-11 is a STAT3 inhibitor.STAT3-IN-11 promotes apoptosis in cancer cells and is a candidate compound for the treatment of cancer.</p>Fórmula:C20H17NO4Pureza:98.3%Cor e Forma:SolidPeso molecular:335.35L6H21
CAS:<p>L6H21 is an MD-2 inhibitor that can be used to study cognitive impairment and brain damage.</p>Fórmula:C18H18O4Pureza:99.26%Cor e Forma:SolidPeso molecular:298.33SMBA1
CAS:<p>SMBA1 is a Bax agonist with antitumor activity that can induce cell cycle arrest and apoptosis in malignant glioma cells.</p>Fórmula:C20H13NO3Pureza:99.2%Cor e Forma:SolidPeso molecular:315.32EC359
CAS:<p>EC359 is a Leukemia Inhibitory Factor Receptor (LIFR) inhibitor with anticancer activity for the study of leukemia and endometrial cancer.</p>Fórmula:C36H38F2O2Pureza:98.11% - 98.11%Cor e Forma:SolidPeso molecular:540.68Simmiparib
CAS:<p>Simmiparib (SMOCL-9112) is a PARP1 and PARP2 inhibitor that promotes apoptosis.Simmiparib is used to study Parkinson's disease and melanoma.</p>Fórmula:C23H18F4N6O2Pureza:99.05% - 99.51%Cor e Forma:SolidPeso molecular:486.42CCCI-01
CAS:<p>CCCI-01: Centrosome cluster inhibitor with anticancer properties, induces apoptosis, aids in non-cross-resistant drug research.</p>Fórmula:C11H9N3O4Pureza:>99.99%Cor e Forma:SolidPeso molecular:247.21KS106
CAS:<p>KS106 inhibits ALDH (1A1: 334 nM, 2: 2137 nM, 3A1: 360 nM), has anti-cancer properties, raises ROS, and promotes aldehyde build-up.</p>Fórmula:C18H15BrF3N3O2SPureza:99.31%Cor e Forma:SolidPeso molecular:474.3Necrostatin-7
CAS:<p>Necrostatin-7 (Necrostatin 7) is a necrotic apoptosis inhibitor with cardioprotective effects that inhibits RANK-NFATc1 signaling.</p>Fórmula:C16H10FN5OS2Pureza:98.71%Cor e Forma:SolidPeso molecular:371.41SD-36
CAS:<p>SD-36: Potent, selective PROTAC STAT3 degrader, Kd ~50 nM, effective on mutants, IC50=10 nM, strong anti-tumor effects, enables mouse tumor regression.</p>Fórmula:C59H62F2N9O12PPureza:98% - >99.99%Cor e Forma:SoildPeso molecular:1158.15Declopramide
CAS:<p>Declopramide (OXI-104) is a chemosensitizer with antitumor activity that can be used to study colorectal cancer and inflammatory bowel disease.</p>Fórmula:C13H20ClN3OPureza:98.53%Cor e Forma:SolidPeso molecular:269.77PD-1/PD-L1-IN-29
CAS:<p>PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction, with an IC50 value of 6.1 nM.</p>Fórmula:C26H24N2O6Cor e Forma:SolidPeso molecular:460.48AZD-5991 Racemate
CAS:<p>AZD-5991 Racemate is the racemate of AZD-5991. (Rac)-AZD-5991 is a novel Mcl-1 inhibitor induces upregulation of BCL2,BCL-XL, CMYC and MCL1 in AML cell lines.</p>Fórmula:C35H34ClN5O3S2Cor e Forma:SolidPeso molecular:672.26CYD-2-11
CAS:<p>CYD-2-11 is an effective and selective Bax agonist. It acts by targeting the structural pocket proximal to S184 in the C-terminal region of Bax.</p>Fórmula:C22H18N2O3Cor e Forma:SolidPeso molecular:358.39QTX125
CAS:<p>QTX125: potent, selective HDAC6 inhibitor with strong antitumor effects.</p>Fórmula:C23H19N3O5Cor e Forma:SolidPeso molecular:417.41Topoisomerase II inhibitor 7
CAS:<p>Topoisomerase II inhibitor 7 halts cell division and induces apoptosis, targeting topoisomerase II alpha with a 3.19 μM IC50.</p>Fórmula:C32H28BrN5O5SCor e Forma:SolidPeso molecular:674.56ATX inhibitor 13
CAS:<p>ATX inhibitor 13: orally active, IC50 3.4 nM, halts RAW264.7 cells at G2, curbs growth/migration, prompts apoptosis, suppresses tumors.</p>Fórmula:C31H35Cl2N5O3Cor e Forma:SolidPeso molecular:596.55(S)-PERK-IN-5
CAS:<p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5TNF-α-IN-1
CAS:<p>TNF-α-IN-1 is a TNF-α inhibitor.</p>Fórmula:C16H14ClN3O5Pureza:98.82%Cor e Forma:SolidPeso molecular:363.75EGFR/HER2/TS-IN-1
CAS:<p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>Fórmula:C24H15N5O4S2Cor e Forma:SolidPeso molecular:501.54Bcl-2/Mcl-1-IN-1
CAS:<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Fórmula:C28H23NO3Cor e Forma:SolidPeso molecular:421.49Se-Methylselenocysteine hydrochloride
CAS:<p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>Fórmula:C4H10ClNO2SePureza:98%Cor e Forma:SolidPeso molecular:218.54VII-31
CAS:<p>VII-31 is an activator of the NEDDylation pathway, capable of inducing apoptosis in MCF-7, PC-3, and MGC-803 cells.</p>Fórmula:C23H25NO5SCor e Forma:SolidPeso molecular:427.51Erbstatin
CAS:<p>Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.</p>Fórmula:C9H9NO3Cor e Forma:SolidPeso molecular:179.17BI-0282
CAS:<p>BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.</p>Fórmula:C30H23Cl2FN4O4Cor e Forma:SolidPeso molecular:593.43BRD0476
CAS:<p>BRD0476 prevents pancreatic β-cell death by blocking IFN-γ-induced JAK2 & STAT1 without inhibiting JAK kinase activity.</p>Fórmula:C35H38N4O8SPureza:98%Cor e Forma:SolidPeso molecular:674.76p-DDAP
CAS:<p>p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.</p>Fórmula:C18H31NOPureza:98%Cor e Forma:SolidPeso molecular:277.44HDAC6-IN-4
CAS:<p>HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.</p>Fórmula:C30H38N2O5Cor e Forma:SolidPeso molecular:506.63PI3K/Akt/mTOR-IN-3
CAS:<p>PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.</p>Fórmula:C34H51NO2Cor e Forma:SolidPeso molecular:505.77Caylin-2
CAS:<p>Nutlin-3 activates p53 by blocking MDM2. Caylin-2, a nutlin-3 analog with trifluoromethyl instead of chlorine, is 10x less potent with an 8 μM IC50.</p>Fórmula:C32H30F6N4O4Cor e Forma:SolidPeso molecular:648.6VEGFR-2/BRAF-IN-2
<p>VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.</p>Fórmula:C26H21ClF3N5O3S2Cor e Forma:SolidPeso molecular:608.05ZT55
CAS:<p>ZT55: Oral JAK2 inhibitor, IC50: 0.031 μM, hinders JAK2 V617F HEL cell growth, induces apoptosis, arrests cell cycle, effective in mice HEL tumor studies.</p>Fórmula:C17H16N2O3Cor e Forma:SolidPeso molecular:296.32TRK-IN-23
CAS:<p>TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L,</p>Fórmula:C20H17FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:364.37PSB 0474
CAS:<p>P2Y6 receptor agonist</p>Fórmula:C17H20N2O13P2Pureza:98%Cor e Forma:SolidPeso molecular:522.29S-Gem
CAS:<p>S-Gem, a thioredoxin reductase (TrxR)-dependent prodrug of Gemcitabine, is selectively activated by TrxR.</p>Fórmula:C13H15F2N3O6S2Pureza:98%Cor e Forma:SolidPeso molecular:411.4MEK-IN-5
CAS:<p>MEK-IN-5: strong MEK inhibitor and NO donor, reduces pMEK/pERK dose/time-dependently, triggers apoptosis in MDA-MB-231 cells.</p>Fórmula:C29H27FN4O10S2Cor e Forma:SolidPeso molecular:674.67Antiproliferative agent-7
CAS:<p>Antiproliferative agent-7 (compound 8f) is a potent anti-proliferative agent. Antiproliferative agent-7 can promote ROS production and induce apoptosis.</p>Fórmula:C28H32N4OCor e Forma:SolidPeso molecular:440.58APPA
CAS:<p>APPA, an aldose reductase inhibitor, demonstrates efficacy in preventing apoptosis and symptoms of Streptozotocin-induced diabetes in rats through inhibition of</p>Fórmula:C14H13NO3Pureza:98%Cor e Forma:SolidPeso molecular:243.26Anticancer agent 67
CAS:<p>Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.</p>Fórmula:C26H24F2N6O2S2Cor e Forma:SolidPeso molecular:554.63Quinidine Monosulfate
CAS:<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Fórmula:C40H50N4O8SCor e Forma:SolidPeso molecular:746.92TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Fórmula:C20H21N5OSCor e Forma:SolidPeso molecular:379.48CK2/ERK8-IN-1
CAS:<p>TMCB inhibits CK2 (Ki: 0.25 µM), ERK8 (IC50: 0.50 µM), PIM1, DYRK1A, HIPK2 (Ki: 8.65-15.25 µM), and induces apoptosis.</p>Fórmula:C11H9Br4N3O2Pureza:98.22%Cor e Forma:SolidPeso molecular:534.82Targapremir-210
CAS:<p>Targapremir-210 (TGP-210) is a miRNA-210 (miRNA-210) inhibitor that inhibits pre-miR-210 processing and induces apoptosis in breast cancer cells.</p>Fórmula:C32H36N10O2Pureza:98%Cor e Forma:SolidPeso molecular:592.69PQ1 Succinate
CAS:<p>PQ1 Succinate boosts GJIC and connexin in breast cancer cells without impacting normal mammary cells.</p>Fórmula:C25H28F3N3O6Cor e Forma:SolidPeso molecular:523.5Anticancer agent 42
CAS:<p>Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.</p>Fórmula:C19H16Cl2N2O3Cor e Forma:SolidPeso molecular:391.25RET-IN-20
<p>RET-IN-20: potent RET inhibitor (IC50 = 13.7 nM), reduces p-Ret/p-Shc, induces apoptosis, anti-tumor effects.</p>Fórmula:C32H33FN6O4Cor e Forma:SolidPeso molecular:584.64Anti-melanoma agent 1
CAS:<p>Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent that induces apoptosis.</p>Fórmula:C28H28N2O2Cor e Forma:SolidPeso molecular:424.53UCD38B HCl
CAS:<p>UCD38B HCl, a cell-permeable uPA inhibitor, induces programmed necrosis in high-grade glioma cells.</p>Fórmula:C15H17Cl2N7O3Pureza:98%Cor e Forma:SolidPeso molecular:414.25HDAC1/6-IN-1
CAS:<p>HDAC1/6-IN-1, a dual HDAC1 (89 nM) and HDAC6 (13 nM) inhibitor, blocks cancer cell cycle, triggers apoptosis, and halts metastasis.</p>Fórmula:C32H45N7O4Cor e Forma:SolidPeso molecular:591.74Metallo-β-lactamase-IN-5
CAS:<p>Metallo-β-lactamase-IN-5 (compound 5c) is a powerful inhibitor of metallo-β-lactamases (MBLs).</p>Fórmula:C19H16N4O3Cor e Forma:SolidPeso molecular:348.362,3-DCPE
CAS:<p>Induces p21, S-phase arrest in cancer cells through ERK pathways. IC50: 0.89 μM (LoVo cells), 12.6 μM (fibroblasts).</p>Fórmula:C11H15Cl2NO2Pureza:98%Cor e Forma:SolidPeso molecular:264.15PERK-IN-5
CAS:<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5MIR96-IN-1
CAS:<p>MIR96-IN-1 selectively inhibits biogenesis of microRNA-96, upregulating a protein target (FOXO1) and inducing apoptosis in cancer cells.</p>Fórmula:C33H48N8O2Cor e Forma:SolidPeso molecular:588.79NSC 146109 hydrochloride
CAS:<p>NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.</p>Fórmula:C17H17ClN2SPureza:99.28%Cor e Forma:SolidPeso molecular:316.85Anticancer agent 76
CAS:<p>Compound CT2-3 is an anticancer agent that hinders growth, induces arrest, ROS, and apoptosis in NSCLC cells.</p>Fórmula:C32H33NO5SCor e Forma:SolidPeso molecular:543.67PD-1-IN-18
CAS:<p>PD-1-IN-18 is a PD1 inhibitor of signaling pathway, and acts as an immunomodulator.</p>Fórmula:C11H17N5O8Pureza:98%Cor e Forma:SolidPeso molecular:347.28NHI-2
CAS:<p>NHI-2 is an LDHA inhibitor (IC50 14.7 µM) that blocks glycolysis, induces apoptosis and cell cycle arrest, and suppresses tumor growth in melanoma models.</p>Fórmula:C17H12F3NO3Pureza:99.981%Cor e Forma:SolidPeso molecular:335.28BMS-242
CAS:<p>BMS-242 is an effective inhibitor of PD-1/PD-L1 interaction.</p>Fórmula:C28H35NO4Pureza:98%Cor e Forma:SolidPeso molecular:449.58CPI-7c
CAS:<p>CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.</p>Fórmula:C22H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:358.39IDT
CAS:<p>IDT, an oral TNFα modulator, changes neutrophil levels, boosts cognition, and reduces tau/amyloid in 3xTgAD mice.</p>Fórmula:C8H5NS2Pureza:98%Cor e Forma:SolidPeso molecular:179.26IDH1 Inhibitor 9
CAS:<p>IDH1 Inhibitor 9 (compound 11S) (2, 4, 8, 10 µM) induces apoptosis and causes cell cycle arrest in the S phase in a dose-dependent manner.</p>Fórmula:C26H30N4O3Cor e Forma:SolidPeso molecular:446.54Ozarelix
CAS:<p>Ozarelix: a GnRH antagonist that induces apoptosis in advanced prostate cancer, modulates death receptors, and reduces sex hormones.</p>Fórmula:C72H96ClN17O14Cor e Forma:SolidPeso molecular:1459.09PARP1-IN-31
CAS:<p>PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC₅₀ of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549).</p>Fórmula:C22H15ClFN3O2Pureza:98.99%Cor e Forma:SolidPeso molecular:407.83Butyrolactone I
CAS:<p>Butyrolactone I (Olomoucin) inhibits CDKs, blocks cdc2 kinases, and shows antitumor activity in lung and prostate cancers.</p>Fórmula:C24H24O7Pureza:98%Cor e Forma:SolidPeso molecular:424.44RIPK1-IN-12
CAS:<p>RIPK1-IN-12: Strong RIPK1 blocker, hinders necroptosis; EC50=1.6 nM (human), 2.9 nM (mouse).</p>Fórmula:C24H26N4O3SCor e Forma:SolidPeso molecular:450.55PARP-2-IN-3
CAS:<p>PARP-2-IN-3 is used in the study of breast cancer as a PARP-2 inhibitor with antitumor activity that induces apoptosis (apoptosis) and necrosis in cancer cells.</p>Fórmula:C20H20ClN3O3Pureza:99.33%Cor e Forma:SolidPeso molecular:385.84Ki23057
CAS:<p>Ki23057, a FGFR2 inhibitor, boosts chemo effects in resistant gastric cancer, may work with SN38/PTX/VP16, enhancing apoptosis via ERCC1/p53 synergy.</p>Fórmula:C30H35N3O4Cor e Forma:SolidPeso molecular:501.623-(3-Phenoxybenzyl)amino-β-carboline
CAS:<p>3-(3-Phenoxybenzyl)amino-β-carboline is a highly effective tubulin inhibitor, selectively degrading αβ-tubulin heterodimers.</p>Fórmula:C24H19N3OCor e Forma:SolidPeso molecular:365.43CU-3
CAS:<p>CU-3 inhibits DGKalpha, reducing cancer growth and boosting anti-cancer immunity.</p>Fórmula:C16H12N2O4S3Pureza:98%Cor e Forma:SolidPeso molecular:392.47EGFR-IN-51
CAS:<p>EGFR-IN-51 effectively inhibits EGFR and mutations with IC50s of 0.493-461.63 μM; it induces apoptosis in cancer cells.</p>Fórmula:C21H15N3O2SCor e Forma:SolidPeso molecular:373.43MM-102
CAS:<p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>Fórmula:C35H49F2N7O4Pureza:98.77% - 99.99%Cor e Forma:SolidPeso molecular:669.8GY1-22
CAS:<p>GY1-22, an inhibitor targeting the DNAJA1-mutP53 R175H interaction pocket, holds potential for cancer research applications.</p>Fórmula:C23H20N4OSCor e Forma:SolidPeso molecular:400.5Infliximab
CAS:<p>Infliximab is a chimeric monoclonal antibody that inhibits TNF-α. Infliximab can be used to treat Crohn's disease and rheumatoid arthritis. Cost-effective and quality-assured.</p>Pureza:98% - 99.70%Cor e Forma:LiquidPeso molecular:149 kDaCS1
CAS:<p>CS1: potent topoisomerase II alpha inhibitor, broad-spectrum antitumor, low toxicity, anti-resistance, induces DNA damage, G2/M arrest, apoptosis.</p>Fórmula:C16H12O3Cor e Forma:SolidPeso molecular:252.26DNA topoisomerase II inhibitor 1
CAS:<p>Potent DNA topoisomerase II blocker; arrests cell cycle, induces apoptosis, anti-growth effects.</p>Fórmula:C28H24N4O3SCor e Forma:SolidPeso molecular:496.58MDM2/XIAP-IN-3
CAS:<p>MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing</p>Fórmula:C29H30N2O5SCor e Forma:SolidPeso molecular:518.62MK-886 sodium salt
CAS:<p>MK-886 sodium salt inhibits leukotriene biosynthesis in leukocytes.</p>Fórmula:C27H33ClNNaO2SCor e Forma:SolidPeso molecular:494.06EGFR/BRAFV600E-IN-1
CAS:<p>EGFR/BRAFV600E-IN-1 inhibits EGFR (0.08 μM) & BRAFV600E (0.15 μM), affects A-549, MCF-7, Panc-1 & HT-29 (IC50: 0.79-1.3 μM).</p>Fórmula:C24H24ClN3O3Cor e Forma:SolidPeso molecular:437.92CFM-5
CAS:<p>CFM-5 has anticonvulsant activity and is used in epilepsy research.</p>Fórmula:C23H18BrN3OSPureza:98%Cor e Forma:SolidPeso molecular:464.38VU0285655-1
CAS:<p>VU0285655-1, a PLD2 inhibitor, halts PLD2-deficient cell growth and protects against high glucose-induced cell death. Used in diabetic retinopathy research.</p>Fórmula:C25H27N5O2Pureza:99.73%Cor e Forma:SolidPeso molecular:429.51IQDMA
CAS:<p>IQDMA is an inhibitor of the transcription factor STAT5.</p>Fórmula:C19H20N4Cor e Forma:SolidPeso molecular:304.39PI3K-IN-34
CAS:<p>PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.</p>Fórmula:C23H22N6O3Cor e Forma:SolidPeso molecular:430.46FAK-IN-5
CAS:<p>FAK-IN-5 is a FAK signaling inhibitor that induces apoptosis and autophagy.</p>Fórmula:C29H29ClF3N3O4Cor e Forma:SolidPeso molecular:576.01MMP-9-IN-3
CAS:<p>MMP-9-IN-3: MMP-9/AKT inhibitor (IC50: 5.56/2.11 nM), forms H-bonds, cytotoxic, induces apoptosis, used in cancer research.</p>Fórmula:C29H25N3O4Cor e Forma:SolidPeso molecular:479.53ZMF-10
CAS:<p>ZMF-10 inhibits PAK1 (IC50: 174 nM), PAK2, PAK3; affects apoptosis, ER stress, migration in cancer studies.</p>Fórmula:C19H17F6N7OCor e Forma:SolidPeso molecular:473.38αβ-Tubulin-IN-1
CAS:<p>αβ-Tubulin-IN-1 is a potent and orally active inhibitor of αβ-Tubulin.</p>Fórmula:C25H19N3O3Cor e Forma:SolidPeso molecular:409.44hnRNPK-IN-1
CAS:<p>hnRNPK-IN-1 binds hnRNPK tightly (Kd 4.6-2.6 μM), disrupting c-myc transcription and inducing apoptosis in Hela cells.</p>Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43MPT0B002
CAS:<p>MPT0B002 is a microtubule inhibitor that acts by downregulating T315I mutant Bcr-Abl and inducing apoptosis of imatinib-resistant chronic myeloid leukemia cells</p>Fórmula:C19H19NO4Pureza:98%Cor e Forma:SolidPeso molecular:325.36Nevanimibe
CAS:<p>Nevanimibe is an orally active and selective inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase 1 (ACAT1) (EC50 of 9 nM).</p>Fórmula:C27H39N3OPureza:98%Cor e Forma:SolidPeso molecular:421.62PARP1-IN-10
CAS:<p>PARP1-IN-10 (12c) is a potent, non-toxic PARP1 inhibitor with a 50.62 nM IC50, enhancing TMZ effects and causing G2/M arrest and apoptosis.</p>Fórmula:C20H23N3O5Cor e Forma:SolidPeso molecular:385.41VEGFR-2-IN-23
CAS:<p>VEGFR-2-IN-23 (11b) is a potent VEGFR-2 inhibitor with an IC50 of 0.34 nM, exhibits antitumor effects, and causes G1 cell cycle arrest.</p>Fórmula:C22H15N5O2Cor e Forma:SolidPeso molecular:381.39MPT0B214
CAS:<p>MPT0B214, a potent microtubule inhibitor, disrupts tubulin polymerization and kills various cancer cells, including drug-resistant types.</p>Fórmula:C20H20N2O5Cor e Forma:SolidPeso molecular:368.38Casein Kinase inhibitor A51
CAS:<p>Casein Kinase inhibitor A51 is a CK1α inhibitor with anticancer activity used in the study of breast and prostate cancer.</p>Fórmula:C18H25ClN6Pureza:99.88%Cor e Forma:SolidPeso molecular:360.88BCL6-IN-7
CAS:<p>BCL6-IN-7 (BCL6 inhibitor-7) is a BCL6 corepressor-interaction inhibitor with potential antitumor activity, used in lymphoma research.</p>Fórmula:C18H15ClN6OPureza:99.03%Cor e Forma:SolidPeso molecular:366.8LQZ-7F
CAS:<p>LQZ-7F is a survivin dimerization inhibitor with anticancer activity.LQZ-7F induces proteasome-dependent survivin degradation and inhibits human tumor growth.</p>Fórmula:C14H7N9O3Pureza:98.64%Cor e Forma:SolidPeso molecular:349.26EM-12
CAS:<p>EM-12, a Thalidomide analogue, is more active, stable, and boosts rat colon cancer studies.</p>Fórmula:C13H12N2O3Pureza:99.34%Cor e Forma:SolidPeso molecular:244.25TAI-1
CAS:<p>TAI-1 is a potent and specific Hec1 inhibitor, which disrupts Hec1-Nek2 protein interaction.</p>Fórmula:C24H21N3O3SPureza:99.58%Cor e Forma:SolidPeso molecular:431.51NLRP3/AIM2-IN-3
CAS:<p>NLRP3/AIM2-IN-3 selectively blocks NLRP3/AIM2 inflammasomes; IC50 for cell lysis is 0.077 μM, disrupting ASC oligomerization.</p>Fórmula:C16H14N2O2Pureza:97.04%Cor e Forma:SolidPeso molecular:266.29F16
CAS:<p>F16 ((E)-4-(3-indolylvinyl)-N-methylpyridinium iodide) inhibits the growth of neu-overexpressing cells and the proliferation of mammary epithelial.</p>Fórmula:C16H15IN2Pureza:99.89%Cor e Forma:SolidPeso molecular:362.21Ro 08-2750
CAS:<p>Ro 08-2750: A non-peptide NGF inhibitor binding NGF (~1 µM IC50) & selectively inhibits p75NTR over TRKA and MSI RNA-binding (2.7 µM IC50).</p>Fórmula:C13H10N4O3Pureza:98.795%Cor e Forma:SolidPeso molecular:270.24Cipepofol
CAS:<p>HSK3486 is similar to propofol and is a general anesthetic, which may have therapeutic potential in insomnia, migraine, anxiety, analgesia, and other aspects.</p>Fórmula:C14H20OPureza:99.77%Cor e Forma:SolidPeso molecular:204.31C6 Ceramide
CAS:<p>C6 Ceramide (N-hexanoylsphingosine) is an activator of the ceramide pathway that arrests cells in the G0/G1 phase by activating ERK.</p>Fórmula:C24H47NO3Pureza:99.67%Cor e Forma:SolidPeso molecular:397.63eIF4A3-IN-1
CAS:<p>eIF4A3-IN-1 is an inhibitor of eukaryotic initiation factor 4A3 (eIF4A3). eIF4A3-IN-1 inhibits cytosolic nonsense-mediated RNA decay at high concentrations.</p>Fórmula:C29H23BrClN5O2Pureza:99.49% - 99.89%Cor e Forma:SolidPeso molecular:588.88Mepazine
CAS:<p>Mepazine, a MALT1 inhibitor, blocks GSTMALT1 (IC50: 0.83μM) and GSTMALT1 325-760 (IC50: 0.42μM), promoting apoptosis and reducing cell viability.</p>Fórmula:C19H22N2SPureza:99.88% - 99.92%Cor e Forma:SolidPeso molecular:310.46HS-276
CAS:<p>HS-276, a selective oral TAK1 inhibitor (Ki: 2.5 nM), also targets CLK2, GCK, ULK2, MAP4K5; potential for RA research.</p>Fórmula:C24H29N5O2Pureza:97.852% - 98.81%Cor e Forma:SolidPeso molecular:419.52CUDC-427
CAS:<p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>Fórmula:C29H36N6O4SPureza:99.92%Cor e Forma:SolidPeso molecular:564.7A 419259 trihydrochloride
CAS:<p>A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).</p>Fórmula:C29H37Cl3N6OPureza:99.75% - 99.96%Cor e Forma:SolidPeso molecular:592Minodronic acid
CAS:<p>Minodronic acid (YM-529) is a P2X2/3 antagonist with anticancer properties, inhibiting cell growth and metastasis, and used in osteoporosis research.</p>Fórmula:C9H12N2O7P2Pureza:98.02%Cor e Forma:SolidPeso molecular:322.15XX-650-23
CAS:<p>XX-650-23 is a CREB inhibitor that induces apoptosis and cell cycle arrest in AML cells and can be used to study acute myeloid leukemia (AML).</p>Fórmula:C18H12N2O2Pureza:97.01%Cor e Forma:SolidPeso molecular:288.3BCP-T.A
CAS:<p>BCP-T.A is an iron death inducer that acts by binding to GPX4.</p>Fórmula:C23H19Cl2N3OSPureza:99.49%Cor e Forma:SolidPeso molecular:456.39Perphenazine dihydrochloride
CAS:<p>Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.</p>Fórmula:C21H28Cl3N3OSPureza:99.67%Cor e Forma:SolidPeso molecular:476.89DK419
CAS:<p>DK419 is an orally active inhibitor of Wnt/β-catenin signaling, with an IC50 of 0.19 μM.</p>Fórmula:C16H8ClF6N3OPureza:99.63%Cor e Forma:SolidPeso molecular:407.7LDCA
CAS:<p>LDCA inhibits LDH-A, disrupts mitochondrial function, induces apoptosis in cancer cells, and is non-toxic.</p>Fórmula:C8H5Cl3FNOPureza:98.99%Cor e Forma:SolidPeso molecular:256.49GSK2593074A
CAS:<p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>Fórmula:C27H23N5OSPureza:99.76%Cor e Forma:SolidPeso molecular:465.57UC-112
CAS:<p>UC-112 is a novel potent IAP inhibitor and potently inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).</p>Fórmula:C22H24N2O2Pureza:99.54%Cor e Forma:SolidPeso molecular:348.44SLMP53-1
CAS:<p>SLMP53-1 is a p53 activator with anti-tumor activity, activates reprogramming of glucose metabolism, and interferes with angiogenesis and migration</p>Fórmula:C20H18N2O2Pureza:99.64%Cor e Forma:SolidPeso molecular:318.37STAT3-IN-13
CAS:<p>STAT3-IN-13 is a STAT3 inhibitor with antiproliferative activity that induces apoptosis and can be used to study breast and liver cancer.</p>Fórmula:C21H20N6O3SPureza:98.89%Cor e Forma:SolidPeso molecular:436.49H2L5186303
CAS:<p>H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.</p>Fórmula:C26H20N2O8Pureza:98.19%Cor e Forma:SolidPeso molecular:488.45Tubulin inhibitor 32
CAS:<p>Tubulin inhibitor 32 is a microtubule inhibitor with antiproliferative and antitumor activity that induces apoptosis and cell cycle arrest in the G2/M phase.</p>Fórmula:C18H19N3O3Pureza:99.92%Cor e Forma:SolidPeso molecular:325.36TL4-12
CAS:<p>TL4-12 is a MAP4K2 (GCK) inhibitor that inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation in vitro.</p>Fórmula:C25H27F3N6O2Pureza:98.38%Cor e Forma:SolidPeso molecular:500.52Exisulind
CAS:<p>Exisulind (CP248) triggers apoptosis via PKG activation, shows antitumor effects, and inhibits growth in various rodent cancer models.</p>Fórmula:C20H17FO4SPureza:97.94%Cor e Forma:SolidPeso molecular:372.41Vamotinib
CAS:<p>Vamotinib (PF-114) is a tyrosine kinase inhibitor with antiproliferative and antitumor activity.Vamotinib is used in the study of Alzheimer's disease.</p>Fórmula:C29H27F3N6OPureza:99.64%Cor e Forma:SolidPeso molecular:532.56VAS 3947
CAS:<p>VAS 3947: NOX inhibitor, induces platelet apoptosis via UPR, not linked to NOX inhibition.</p>Fórmula:C14H10N6OSPureza:98.44%Cor e Forma:SolidPeso molecular:310.33RIPK3-IN-1
CAS:<p>RIPK3-IN-1 is a RIPK3 inhibitor (IC50: 9.1 nM) that inhibits c-Met kinase, RIPK1, and RIPK2 activity and can be used to study apoptosis.</p>Fórmula:C29H25FN4O4Pureza:98.27%Cor e Forma:SolidPeso molecular:512.53Ro24-7429
CAS:<p>Ro24-7429: oral HIV-1 Tat antagonist, RUNX1 inhibitor with anti-HIV, antifibrotic, and anti-inflammatory properties.</p>Fórmula:C14H13ClN4Pureza:99.29% - 99.85%Cor e Forma:SolidPeso molecular:272.73LCS3
CAS:<p>LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3</p>Fórmula:C11H7ClN2O4Pureza:99.68%Cor e Forma:SolidPeso molecular:266.64R306465
CAS:<p>R306465 (JNJ-16241199) is an HDAC 1 inhibitor with broad-spectrum anti-tumor activity, inducing apoptosis, and can be used to study solid tumors.</p>Fórmula:C19H19N5O4SPureza:98.46% - 99.54%Cor e Forma:SolidPeso molecular:413.45Atrosab
CAS:<p>Atrosab is a humanized IgG1 antibody targeting TNFR1, inhibiting TNF-mediated apoptosis, and can be used to study inflammatory and neurodegenerative diseases.</p>Pureza:SDS-PAGE:>95%;SEC-HPLC:95.22%Cor e Forma:LiquidPeso molecular:146.12 kDaDasatinib hydrochloride
CAS:<p>Dasatinib hydrochloride is an oral Src/Bcr-Abl inhibitor with potent antitumor effects, Ki values of 16 pM (Src) and 30 pM (Bcr-Abl).</p>Fórmula:C22H27Cl2N7O2SPureza:99.88% - 99.98%Cor e Forma:SolidPeso molecular:524.47SYM 2081
CAS:<p>SYM 2081: Kainate receptor agonist, IC50 of 35 nM, depolarizes muscle, lowers EPSP amplitude.</p>Fórmula:C6H11NO4Pureza:99.59%Cor e Forma:SolidPeso molecular:161.16Trk-IN-9
CAS:<p>Trk-IN-9 is a TRK inhibitor with anticancer and antiproliferative activity and can be used in cancer research.</p>Fórmula:C23H24ClFN6OPureza:98.15%Cor e Forma:SolidPeso molecular:454.93KR-33493
CAS:<p>KR-33493 is a FAS-associated factor 1 (FAF1) inhibitor and can be used in studies about Parkinson's disease.</p>Fórmula:C20H18BrN3O3SPureza:99.96%Cor e Forma:SolidPeso molecular:460.34AZA1
CAS:<p>AZA1 (Rac1/Cdc42-IN-1) is a potent dual inhibitor of Rac1 and Cdc42.</p>Fórmula:C22H20N6Pureza:99.75%Cor e Forma:SolidPeso molecular:368.43EB1
CAS:<p>EB1 is an MNK kinase inhibitor that inhibits cancer cell growth, promotes apoptosis, and inhibits eIF4E phosphorylation.</p>Fórmula:C18H14N4Pureza:99.82%Cor e Forma:SolidPeso molecular:286.33SPD304 dihydrochloride
CAS:<p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>Fórmula:C32H34Cl2F3N3O2Pureza:99.25%Cor e Forma:SolidPeso molecular:620.53CMLD-2
CAS:<p>CMLD-2 is a HuR-ARE inhibitor (Ki: 350 nM) that promotes apoptosis, has antitumor properties, and reduces thyroid cancer cell viability.</p>Fórmula:C31H31NO6Pureza:99.99%Cor e Forma:SolidPeso molecular:513.58Sarmustine
CAS:<p>SarCNU is an alkylating anticancer drug targeting prostate cancer through p53 pathways and selects P140K MGMT-transduced CD34(+) cells.</p>Fórmula:C6H11ClN4O3Pureza:98.29% - 99.71%Cor e Forma:SolidPeso molecular:222.63N6-Cyclopentyladenosine
CAS:<p>N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of</p>Fórmula:C15H21N5O4Pureza:99.84%Cor e Forma:SolidPeso molecular:335.36Cot inhibitor-1
CAS:<p>Cot inhibitor-1 selectively blocks Tpl2 kinase, reducing TNF-alpha in blood (IC50: 5.7 nM). It may treat arthritis, IBD, and certain cancers.</p>Fórmula:C27H27Cl2FN8Pureza:98.59%Cor e Forma:SolidPeso molecular:553.46Ciglitazone
CAS:<p>Ciglitazone: potent PPARγ agonist, EC50 3 μM, oral hypoglycemic; reduces insulin, blood pressure, Th17 cells, VEGF; halts gastric cancer growth.</p>Fórmula:C18H23NO3SPureza:98.23% - 99.59%Cor e Forma:White Cyrstalline SolidPeso molecular:333.451G244
CAS:<p>1G244 is an inhibitor of DPP8/9 with antiatherosclerotic and antimyeloma properties.</p>Fórmula:C29H30F2N4O2Pureza:99.14%Cor e Forma:SolidPeso molecular:504.57Tubulin inhibitor 11
CAS:<p>Potent, oral Tubulin inhibitor 11 hinders polymerization, targets Colchicine site, induces mitotic block, and apoptosis.</p>Fórmula:C22H23N3O3SPureza:98.32%Cor e Forma:SoildPeso molecular:409.5Sabizabulin
CAS:<p>Sabizabulin (ABI-231) is a potent, orally bioavailable α- and β-tubulin inhibitor.Cost-effective and quality-assured.</p>Fórmula:C21H19N3O4Pureza:98.10% - 99.79%Cor e Forma:SolidPeso molecular:377.39P505-15 Acetate
CAS:<p>P505-15 Acetate inhibits spleen tyrosine kinase, reduces immune response and inflammation, and lowers arthritis severity.</p>Fórmula:C21H27N9O3Pureza:99.99%Cor e Forma:SolidPeso molecular:453.5Tiomolibdate diammonium
CAS:<p>Tiomolibdate diammonium (NSC-286644) blocks SOD1 and COX, acting as an antiangiogenic and antitumor agent.</p>Fórmula:H8MoN2S4Pureza:98%Cor e Forma:Brown To Black Iridescent Crystalline PowderPeso molecular:260.28SB 699551 dihydrochloride
CAS:<p>SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.</p>Fórmula:C34H47Cl2N3OPureza:99.83%Cor e Forma:SolidPeso molecular:584.66Antifolate C2
CAS:<p>Antifolate C2 (AGF 154) inhibits tumor growth with 0.14 nM IC, useful in cancer/autoimmune research.</p>Fórmula:C19H21N5O6SPureza:99.57%Cor e Forma:SolidPeso molecular:447.46Triciribine phosphate
CAS:<p>Triciribine phosphate (VD 002) is an AKT inhibitor that inhibits neovascularization and can be used in the study of leukemia.</p>Fórmula:C13H17N6O7PPureza:97.94%Cor e Forma:SolidPeso molecular:400.28NSC49652
CAS:<p>NSC49652 triggers apoptotic cell death dependent on p75NTR and JNK activity in neurons and melanoma cells, and inhibits tumor growth in a melanoma mouse model.</p>Fórmula:C14H11NO2Pureza:98.98%Cor e Forma:SolidPeso molecular:225.24Lanperisone HCl
CAS:<p>Lanperisone (NK433) is a potent, long-lasting muscle relaxant that inhibits spinal reflexes via noradrenergic system suppression.</p>Fórmula:C15H19ClF3NOPureza:98.67% - >99.99%Cor e Forma:SolidPeso molecular:321.77CDK9-IN-7
CAS:<p>CDK9-IN-7: selective, oral CDK9/cyclin T inhibitor with 11 nM IC50, stronger than CDK4/6.</p>Fórmula:C29H37N7O2SPureza:98.08%Cor e Forma:SolidPeso molecular:547.71Droloxifene
CAS:<p>Droloxifene, a tamoxifen derivative and oral SERM, induces p53 and apoptosis; Fluroxifene protects bone, blocks estrogen and implantation.</p>Fórmula:C26H29NO2Pureza:99.86% - 99.97%Cor e Forma:Solid PowderPeso molecular:387.51CCT018159
CAS:<p>CCT018159: ATP-competitive HSP90 inhibitor, IC50 3.2 μM (human), 6.6 μM (yeast), blocks invasion, angiogenesis, induces G1 arrest and apoptosis.</p>Fórmula:C20H20N2O4Pureza:98.78% - 99.79%Cor e Forma:SolidPeso molecular:352.38T025
CAS:<p>T025 inhibits CLK1-4 (Kds: 0.074-6.5 nM), shows anti-cancer effects (IC50: 30-300 nM), useful for MYC-related disease research.</p>Fórmula:C21H18N8Pureza:98.08%Cor e Forma:SolidPeso molecular:382.42HTH-01-091
CAS:<p>HTH-01-091 is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor (IC50: 10.5 nM).HTH-01-091 inhibits PIM1/2/3, RIPK2, DYRK3,</p>Fórmula:C26H28Cl2N4O2Pureza:98.4%Cor e Forma:SolidPeso molecular:499.43GS-9191
CAS:<p>GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which</p>Fórmula:C37H51N8O6PPureza:98.01 - 99.28%Cor e Forma:SolidPeso molecular:734.82Ro 90-7501
CAS:<p>Ro 90-7501, an amyloid β42 (Aβ42) protofibril and TPR-dependent PP5 inhibitor, is a novel cervical cancer cell radiosensitizer that inhibits HCMV.</p>Fórmula:C20H16N6Pureza:97.21% - 99.72%Cor e Forma:SolidPeso molecular:340.38UCB-5307
CAS:<p>UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.</p>Fórmula:C22H21N3OPureza:98.76%Cor e Forma:SolidPeso molecular:343.42cRIPGBM chloride
CAS:<p>cRIPGBM chloride is a pro-apoptotic derivative found in GBM cancer stem cells with anti-tumor activity, inducing caspase-1-dependent apoptosis.</p>Fórmula:C26H20ClFN2O2Pureza:99.75%Cor e Forma:SolidPeso molecular:446.9Brigimadlin
CAS:<p>Brigimadlin (BI 907828) is an orally active and highly potent antagonist of the E3 ubiquitin-protein ligase MDM2-p53 with antitumor activity.</p>Fórmula:C31H25Cl2FN4O3Pureza:98.17%Cor e Forma:SolidPeso molecular:591.46ZDLD20
CAS:<p>ZDLD20 is a CDK4 inhibitor with anti-HCT116 and anticancer activity that inhibits colony formation and blocks the G1 phase of the cell cycle.</p>Fórmula:C22H22N6OPureza:98.59%Cor e Forma:SolidPeso molecular:386.45UNC0321
CAS:<p>UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.</p>Fórmula:C27H45N7O3Pureza:99.80%Cor e Forma:SolidPeso molecular:515.69MBM-55
CAS:<p>MBM-55 is an effective inhibitor of NIMA related kinase 2 (NEK2) with an IC50 of 1 nM.</p>Fórmula:C28H27FN6O2Pureza:99.83%Cor e Forma:SolidPeso molecular:498.55Prinomastat
CAS:<p>Prinomastat: orally active, crosses blood-brain barrier, inhibits MMP-1/2/3/9, Ki/IC50s: 0.05-0.3/5.0-79 nM, antitumor.</p>Fórmula:C18H21N3O5S2Pureza:99.23%Cor e Forma:SolidPeso molecular:423.51Anticancer agent 110
CAS:<p>Anticancer Agent 110 exhibits potent in vitro anti-leukemia activity, demonstrating high cytotoxicity against K-562 lineage chronic myelogenous leukemia cells</p>Fórmula:C18H13FN6OSPureza:98%Cor e Forma:SolidPeso molecular:380.4DCG066
CAS:<p>DCG066 is an inhibitor of lysine methyltransferase G9a with anticancer activity and may be used in the study of leukemia.</p>Fórmula:C30H31F6N3O2Pureza:98.26% - 98.38%Cor e Forma:SolidPeso molecular:579.58Triparanol
CAS:<p>Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1</p>Fórmula:C27H32ClNO2Pureza:99.72%Cor e Forma:SolidPeso molecular:438D609
CAS:<p>D609 (Tricyclodecan-9-yl-Xanthogenate) has antiviral and antiproliferative activities.D609 acts through competitive inhibition of PC, PC-P and SMS.</p>Fórmula:C11H15KOS2Pureza:97.67% - 99.56%Cor e Forma:Off-White PowderPeso molecular:266.46JY-2
CAS:<p>JY-2 is a forkhead transcription factor O1 (FoxO1) inhibitor with antidiabetic activity that inhibits FoxO1 transcription and can be used to study psoriasis.</p>Fórmula:C13H7Cl2N3OPureza:99.66%Cor e Forma:SolidPeso molecular:292.12TT01001
CAS:<p>TT01001, a mitoNEET agonist, may treat type II diabetes by reducing oxidative stress and preventing neuronal death.</p>Fórmula:C15H19Cl2N3O2SPureza:99.93%Cor e Forma:SolidPeso molecular:376.3RET-IN-23
CAS:<p>RET-IN-23 is an orally available and highly potent RET inhibitor with significant antitumor activity for the study of non-small cell lung cancer.</p>Fórmula:C28H28FN11Pureza:97.46%Cor e Forma:SolidPeso molecular:537.59HBDDE
CAS:<p>HBDDE inhibits PKCα/γ (IC50: 43/50 μM), favors them over PKCδ/βI/βII, and induces neuronal apoptosis. Derived from ellagic acid.</p>Fórmula:C16H18O8Pureza:97.94%Cor e Forma:SolidPeso molecular:338.31HBED
CAS:<p>HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.</p>Fórmula:C20H24N2O6Pureza:97.35% - 98.58%Cor e Forma:SolidPeso molecular:388.41Etomoxir
CAS:<p>Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1a (CPT-1a) (IC50=5-20 nM), inhibits fatty acid oxidation. High-Quality, Low-Cost!</p>Fórmula:C17H23ClO4Pureza:98% - 99.39%Cor e Forma:SolidPeso molecular:326.82DB1976
CAS:<p>DB1976: Selenophene DB270 analog, inhibits PU.1 (IC50=10 nM), disrupts PU.1/DNA (KD=12 nM), induces apoptosis, cell-permeable.</p>Fórmula:C20H16N8SePureza:98.74%Cor e Forma:SolidPeso molecular:447.35GSK-3β inhibitor 3
CAS:<p>GSK-3β inhibitor 3 is a covalent inhibitor (IC50: 6.6 μM) of glycogen synthase kinase 3β (GSK-3β) that is potent, selective, and irreversible.GSK-3β inhibitor 3</p>Fórmula:C18H14FNO2SPureza:97.53%Cor e Forma:SolidPeso molecular:327.37EGFR-IN-11
CAS:<p>EGFR-IN-11 selectively blocks EGFR-tyrosine kinase and promotes apoptosis; targets EGFRL858R/T790M/C797S, IC50=18 nM; halts cell cycle at G0/G1.</p>Fórmula:C29H35N9O2SPureza:99.93%Cor e Forma:SolidPeso molecular:573.71GCN2-IN-1
CAS:<p>GCN2-IN-1 (A-92) is an effective GCN2 inhibitor and can be used in research on the treatment of cancer as a chemotherapeutic agent.</p>Fórmula:C19H18N10OPureza:99.49% - 99.64%Cor e Forma:SolidPeso molecular:402.41DX3-213B
CAS:<p>DX3-213B is a potent, orally active inhibitor of oxidative phosphorylation (OXPHOS) complex I with an IC50 of 3.6 nM.</p>Fórmula:C20H28F2N2O5S2Pureza:99.85%Cor e Forma:SolidPeso molecular:478.57RS1-PDK1 inhibitor
CAS:<p>RS1-PDK1 inhibitor (RS 1) is a selective inhibitor of the protein kinase PDK1 that can be used to treat and prevent disease or disorders.</p>Fórmula:C15H9ClN2O2S3Pureza:98.12%Cor e Forma:SolidPeso molecular:380.89iCRT-5
CAS:<p>iCRT-5 is a potent inhibitor of the Wnt pathway. iCRT-5 has antiproliferative activity and can be used in the study of multiple myeloma.</p>Fórmula:C16H17NO5S2Pureza:99.68%Cor e Forma:SolidPeso molecular:367.44Epristeride
CAS:<p>Epristeride (ONO-9302) is a steroidal 5-alpha-reductase isoform 2 inhibitor that inhibits SR isoform 2. Epristeride reduces prostate size.</p>Fórmula:C25H37NO3Pureza:98.12% - >99.99%Cor e Forma:SolidPeso molecular:399.57UK-101
CAS:<p>UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM</p>Fórmula:C25H48N2O5SiPureza:99.08% - 99.25%Cor e Forma:SolidPeso molecular:484.74RO-5963
CAS:<p>RO-5963 is a dual inhibitor of p53-MDM2 and p53-MDMX (IC50s: ~17 nM and ~24 nM, respectively).</p>Fórmula:C24H21ClF2N4O5Pureza:99.28%Cor e Forma:SolidPeso molecular:518.9Alethine
CAS:<p>Alethine is a small antitumor compound used to treat cancers and infections, boosting T-cell cytotoxicity by raising TNFα.</p>Fórmula:C10H22N4O2S2Pureza:98.83%Cor e Forma:SolidPeso molecular:294.44Pyrazoloacridine
CAS:<p>Pyrazoloacridine (PD 115934) binds DNA, inhibits topo I/II, has 1.25 μM IC50 in K562 cells, and exhibits anti-cancer effects.</p>Fórmula:C19H21N5O3Pureza:99.72%Cor e Forma:SolidPeso molecular:367.4Stemazole
CAS:<p>Stemazole activates human stem cell growth, boosts survival, reduces cell death, and aids myelin repair, with therapeutic potential in demyelinating diseases.</p>Fórmula:C9H9N5OS2Pureza:98.57%Cor e Forma:SolidPeso molecular:267.33GSK854
CAS:<p>GSK854 is a selective TNNI3K inhibitor reducing heart damage and stress post-infarction in mice.</p>Fórmula:C18H19ClN6O4S2Pureza:98.79%Cor e Forma:SolidPeso molecular:482.96CBS9106
CAS:<p>CBS9106 (SL-801) is a CRM1 inhibitor with CRM1-degrading and anti-tumor activity that inhibits CRM1-dependent nuclear export.</p>Fórmula:C18H21ClF3N3O3Pureza:98.98%Cor e Forma:SolidPeso molecular:419.83A09-003
CAS:<p>A09-003 Inhibits the proliferation of leukemia cell lines and inhibits the increase of leukemia sequence-1 protein in HI bone marrow cells.</p>Fórmula:C23H26N4OPureza:99.61%Cor e Forma:SolidPeso molecular:374.48OR-1896
CAS:<p>OR-1896 is a PDE III inhibitor, a vasodilator with partial anti-inflammatory properties, and can be used to study heart failure and vascular dysfunction.</p>Fórmula:C13H15N3O2Pureza:99.33%Cor e Forma:SolidPeso molecular:245.28SCFSkp2-IN-2
CAS:<p>SCFSkp2-IN-2, a Skp2 inhibitor, exhibits a dissociation constant (K_D) of 28.77 μM.</p>Fórmula:C17H20N4O2Pureza:99.86%Cor e Forma:SolidPeso molecular:312.37PARP/PI3K-IN-1
CAS:<p>PARP/PI3K-IN-1 is a PARP and PI3K dual inhibitor with anticancer and antiproliferative activities for the study of breast, pancreatic and lung cancers.</p>Fórmula:C33H28F4N8O3Pureza:99.59%Cor e Forma:SolidPeso molecular:660.62TC-DAPK 6
CAS:<p>TC-DAPK 6 is an ATP-competitive inhibitor of Death-associated protein kinase (DAPK) with IC50s of 69 and 225 nM for DAPK1 and DAPK3.</p>Fórmula:C17H12N2O2Pureza:98.73%Cor e Forma:SolidPeso molecular:276.29AMG PERK 44
CAS:<p>AMG PERK 44 is a PERK inhibitor that induces autophagy.AMG PERK 44 inhibits GCN2 and B-Raf and can be used in cancer research.</p>Fórmula:C34H29ClN4O2Pureza:98.8% - 99.81%Cor e Forma:SolidPeso molecular:561.07Apostatin-1
CAS:<p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>Fórmula:C19H27N3OSPureza:99.31%Cor e Forma:SolidPeso molecular:345.5Bomedemstat ditosylate
CAS:<p>Bomedemstat (IMG-7289) is an LSD1 inhibitor for acute myeloid leukemia, MDS, and Myelofibrosis; induces apoptosis by regulating p53, PUMA, and BCLXL.</p>Fórmula:C42H50FN7O8S2Pureza:99.05%Cor e Forma:SolidPeso molecular:864.02
