Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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BU 224 hydrochloride
CAS:<p>BU 224 hydrochloride is a selective imidazoline I(2) binding site ligand and has antinociceptive and antidepressant-like activities.</p>Fórmula:C12H12ClN3Pureza:99.51%Cor e Forma:SolidPeso molecular:233.7Rozanolixizumab
CAS:<p>Rozanolixizumab (RYSTIGGO) is a humanized IgG4 monoclonal antibody that targets FcRn in newborns for autoimmune research.</p>Pureza:SDS-PAGE:97.2%;SEC-HPLC:95.9%Cor e Forma:LiquidPeso molecular:145.19 kDaPROTAC SMARCA2/4 degrader-38
<p>PROTACSMARCA2/4 degrader-38 is a SMARCA2/4 PROTAC degrader with DC50 values of 3.0 nM and 4.0 nM, respectively. It facilitates the ubiquitination and degradation of SMARCA2/4 and can block the G0/G1 phase of the cell cycle, leading to the induction of apoptosis. PROTACSMARCA2/4 degrader-38 is applicable in acute myeloid leukemia (AML) research.</p>Cor e Forma:Odour SolidEPZ020411 hydrochloride
CAS:<p>EPZ020411 hydrochloride is a selective and potent small molecule PRMT6 inhibitor with an IC50 value of 10 nM.</p>Fórmula:C25H39ClN4O3Pureza:99.88%Cor e Forma:SolidPeso molecular:479.05PROTAC HDAC6 degrader 1
CAS:<p>Compound A6, a potent PROTAC HDAC6 degrader, has a DC50 of 3.5 nM and induces apoptosis in myeloid leukemia cells.</p>Fórmula:C37H46N6O10Cor e Forma:SolidPeso molecular:734.8Thalidomide-NH-C6-NH2
CAS:<p>Thalidomide-NH-C6-NH2 is a synthetic conjugate compound designed as an E3 ligase ligand-linker.</p>Fórmula:C19H24N4O4Pureza:98%Cor e Forma:SolidPeso molecular:372.42Polyphyllin G
CAS:<p>Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas.</p>Fórmula:C51H84O22Pureza:98%Cor e Forma:SolidPeso molecular:1049.21Isovalerylcarnitine
CAS:<p>Isovalerylcarnitine (3-methylbutyrylcarnitine) is a selective effective calpain activator that can promote cell apoptosis and is related to isovaleric acidemia.</p>Fórmula:C12H23NO4Pureza:98.24%Cor e Forma:SolidPeso molecular:245.32Methoxyacetic acid
CAS:<p>Methoxyacetic acid is an endogenous metabolite.</p>Fórmula:C3H6O3Cor e Forma:Less Liquid (Ntp 1992) Physical Description Colorless Liquid (Ntp 1992)Peso molecular:90.083,4,5-Trihydroxycinnamic acid decyl ester
CAS:<p>3,4,5-Trihydroxycinnamic acid decyl ester is an anti-obesity agent that inhibits lipid absorption and pancreatic lipase (EC50 ≈ 0.9μM).</p>Fórmula:C19H28O5Pureza:98.28%Cor e Forma:SolidPeso molecular:336.4213-Methyltetradecanoic acid
CAS:<p>LeDSF3 controls HSAF production in Lysobacter, has antifungal properties, and acts as an anti-tumor by inhibiting p-AKT and activating caspase-3.</p>Fórmula:C15H30O2Cor e Forma:SolidPeso molecular:242.4Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride
CAS:<p>Thalidomide-O-amido-PEG4-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate incorporating the Thalidomide-based cereblon ligand and a</p>Fórmula:C25H35ClN4O10Pureza:98%Cor e Forma:SolidPeso molecular:587.02Pexidartinib hydrochloride
CAS:<p>Pexidartinib HCl is a potent, selective CSF1R and c-Kit inhibitor with IC50s of 20 nM and 10 nM, respectively, showing anti-tumor activity.</p>Fórmula:C20H16Cl2F3N5Cor e Forma:SolidPeso molecular:454.28CuATSP
CAS:<p>CuATSP is a potent free radical trapping antioxidant (RTA) and ferroptosis inhibitor inhibit lipid peroxidation, for (ALS) and Parkinson's disease.</p>Fórmula:C18H18CuN6S2Pureza:97.09%Cor e Forma:SolidPeso molecular:446.05Mepazine hydrochloride
CAS:<p>Mepazine hydrochloride (Pecazine hydrochloride) is a MALT1 inhibitor with anticancer and antitumor activity, inhibiting RANK-induced osteoclastogenesis.</p>Fórmula:C19H23ClN2SPureza:99.76%Cor e Forma:SolidPeso molecular:346.92Bax inhibitor peptide V5
CAS:<p>Bax inhibitor peptide V5 (BIP-V5) is a Bax-mediated apoptosis inhibitor with anticancer activity.</p>Fórmula:C27H50N6O6SCor e Forma:SolidPeso molecular:586.79Saquinavir mesylate
CAS:Saquinavir mesylate (Ro 31-8959/003) is an Inhibitor of HIV Proteaseused in antiretroviral therapyFórmula:C39H54N6O8SPureza:99.19%Cor e Forma:White Or Pale Yellow PowderPeso molecular:766.9FKBP12 PROTAC RC32
CAS:<p>FKBP12 PROTAC RC32 is a PROTAC-like degrader targeting FKBP12. It can degrade FKBP12 in organs after intraperitoneal administration.</p>Fórmula:C75H107N7O20Pureza:98.57% - 99.57%Cor e Forma:SolidPeso molecular:1426.69Tubulin inhibitor 1
CAS:Tubulin inhibitor 1 blocks tubulin polymerization, with strong anti-tumor effects, induces apoptosis and G2/M mitotic arrest.Fórmula:C21H24N2O4Pureza:98%Cor e Forma:SolidPeso molecular:368.43Venetoclax-d8
CAS:Venetoclax-d8 (ABT-199-d8) is a deuterated form of Venetoclax, a potent, selective, and orally active Bcl-2 inhibitor that induces autophagy and apoptosis.Fórmula:C45H42D8ClN7O7SCor e Forma:SolidPeso molecular:876.49PR-924
CAS:<p>PR-924 is a selective inhibitor of tripeptide epoxyketone immunoproteasome subunit LMP-7 (IC50: 22 nM).</p>Fórmula:C37H38N4O5Pureza:98%Cor e Forma:SolidPeso molecular:618.72Nafamostat
CAS:<p>Nafamostat is a synthetic serine protease inhibitor and an anticoagulant used in haemodialysis. It induces apoptosis, inhibiting SARS-CoV-2 and COVID-19.</p>Fórmula:C19H17N5O2Pureza:98%Cor e Forma:SolidPeso molecular:347.37MM-401 TFA
CAS:<p>MM-401 (TFA), an MLL1 H3K4 methylation inhibitor (IC50 = 0.32 µM), blocks MLL1-WDR5, causing cell cycle arrest and apoptosis, for MLL leukemia studies.</p>Fórmula:C31H47F3N8O7Cor e Forma:SolidPeso molecular:700.75KRA-533
CAS:<p>KRA-533 is an effective KRAS agonist that targets the GTP/GDP binding pocket within the KRAS protein, inhibiting GTP cleavage.</p>Fórmula:C13H16BrNO3Pureza:98.11%Cor e Forma:SolidPeso molecular:314.185-NIdR
CAS:<p>5-NIdR is a Nucleoside Derivative - Indole nucleoside.</p>Fórmula:C13H14N2O5Cor e Forma:SolidPeso molecular:278.26VK3-OCH3
CAS:Fórmula:C14H14O3SPureza:>98.0%(HPLC)Cor e Forma:Light yellow to Yellow to Orange powder to crystalPeso molecular:262.32Etoposide Phosphate
CAS:<p>Etoposide Phosphate is a selective and orally active topoisomerase II inhibitor and anticancer chemotherapy drug that apoptosise, the p53, and G2/M</p>Fórmula:C29H33O16PCor e Forma:SolidPeso molecular:668.54J22352
CAS:<p>J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects in</p>Fórmula:C24H21N3O4Cor e Forma:SolidPeso molecular:415.44Forodesine hydrochloride
CAS:<p>Forodesine hydrochloride blocks lymphocyte growth and induces leukemia cell death by inhibiting PNP, effective across species.</p>Fórmula:C11H15ClN4O4Cor e Forma:SolidPeso molecular:302.71NCX 4040
CAS:<p>COX-2 expression inhibitor</p>Fórmula:C16H13NO7Pureza:98%Cor e Forma:SolidPeso molecular:331.28SB 202190 hydrochloride
CAS:<p>SB 202190 hydrochloride is a p38 MAPK inhibitor that inhibits p38α and p38β2 with selective, cell-permeable, and antitumor ,differentiation to cardiomyocytes.</p>Fórmula:C20H15ClFN3OPureza:99.99%Cor e Forma:SolidPeso molecular:367.8Thalidomide D4
CAS:<p>Thalidomide D4 is a deuterium labeled Thalidomide, has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.</p>Fórmula:C13H10N2O4Pureza:98%Cor e Forma:SolidPeso molecular:262.25Isoalantolactone
CAS:Fórmula:C15H20O2Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:232.32(Rac)-Apremilast D5
CAS:<p>(Rac)-Apremilast D5 is a deuterium-labeled version of the enantiomer (R)-Apremilast, also known as (R)-CC-10004, which itself is one specific form of Apremilast</p>Fórmula:C22H24N2O7SPureza:98%Cor e Forma:SolidPeso molecular:465.53GO-203
CAS:<p>GO-203 is a useful organic compound for research related to life sciences. The catalog number is T35351 and the CAS number is 1222186-26-6.</p>Fórmula:C89H171F3N52O21S2Cor e Forma:SolidPeso molecular:2426.81PETCM
CAS:PETCM is a caspase-3 activator and acts as an cytochrome c (cyto c)-dependent manner.Fórmula:C8H8Cl3NOPureza:98%Cor e Forma:SolidPeso molecular:240.51AZT triphosphate
CAS:<p>AZT triphosphate is a Nucleoside Triphosphate.</p>Fórmula:C10H16N5O13P3Cor e Forma:SolidPeso molecular:507.18Thalidomide-Piperazine 5-fluoride
CAS:<p>Thalidomide-Piperazine 5-fluoride: a cereblon ligand-linked E3 ligase via PROTAC tech.</p>Fórmula:C17H17FN4O4Cor e Forma:SolidPeso molecular:360.34Sunitinib-d10
CAS:<p>Sunitinib D10, a deuterium-enriched version, inhibits VEGFR2 and PDGFRβ tyrosine kinases (IC50: 80 nM/2 nM).</p>Fórmula:C22H27FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:408.54Thalidomide-O-amido-PEG-C2-NH2
CAS:<p>Thalidomide-based cereblon ligand linked to PEG-C2-NH2 for use in PROTAC E3 ligase conjugates.</p>Fórmula:C19H22N4O7Cor e Forma:SolidPeso molecular:418.4Prinaberel
CAS:<p>Prinaberel (ERB-041) is an effective and selective ERβ agonist and >200-fold selective for ERβ.</p>Fórmula:C15H10FNO3Pureza:97.1%Cor e Forma:SolidPeso molecular:271.245-(N,N-Hexamethylene)-amiloride
CAS:<p>5-(N,N-Hexamethylene)-amiloride (5-HMA) is an amiloride derivative that inhibits TRPA1-mediated calcium signaling (IC50: 35 μM). It functions as an inhibitor of the Na+/H+ exchanger (NHE) with Ki values ranging from 0.013 to 2.4 μM for various NHE isoforms. Additionally, 5-HMA blocks ASIC3 channels by 51% at 20 μM.</p>Fórmula:C12H18ClN7OPureza:85.48%Cor e Forma:SolidPeso molecular:311.77Metronidazole-d4
CAS:<p>Metronidazole-d4 is a deuterium labeled compound isotopic tracing.Metronidazole is an antibiotic and antiprotozoal oral and BBB penetration anaerobic bacteria.</p>Fórmula:C6H9N3O3Cor e Forma:SolidPeso molecular:175.18Gum arabic
CAS:<p>Gum Arabic, from A. Senegal, is an antioxidant that defends against hepatic, renal, and cardiac toxicities and aids in immunohistochemistry.</p>Cor e Forma:SolidMC1742
CAS:<p>MC1742 inhibits class I/IIb HDACs, blocks sarcoma CSC growth, and reactivates latent HIV. IC50: HDAC1-3/8 (0.02-0.61 μM), HDAC6/10 (7-40 nM).</p>Fórmula:C21H21N3O3SPureza:99.20%Cor e Forma:SolidPeso molecular:395.48Forodesine
CAS:<p>Forodesine inhibits lymphocyte growth and induces apoptosis in leukemic cells; oral purine nucleoside phosphorylase blocker; IC50: 0.48-1.57 nM.</p>Fórmula:C11H14N4O4Pureza:98.75% - 99.88%Cor e Forma:SolidPeso molecular:266.25Thalidomide-O-amido-PEG3-C2-NH2 hydrochloride
CAS:<p>Thalidomide-based E3 ligase linker for PROTACs with a PEG3 chain and hydrochloride salt.</p>Fórmula:C23H31ClN4O9Pureza:98%Cor e Forma:SolidPeso molecular:542.97Celosin K
CAS:<p>Celosin K (compound 8), isolated from Semen Celosiae seeds, effectively inhibits t-BHP-induced neuronal injury.</p>Fórmula:C47H74O19Pureza:98%Cor e Forma:SolidPeso molecular:943.08PI3Kα-IN-9
CAS:<p>PI3Kα-IN-9 is an inhibitor of PI3Kα and PI3Kα with antiproliferative activity, inhibits PI3Kα, PI3Kγ, PI3Kδ, and PI3Kβ, induces apoptosis.</p>Fórmula:C18H21N7O3Pureza:98.29%Cor e Forma:SolidPeso molecular:383.4Olanzapine D3
CAS:<p>Olanzapine D3 is the deuterium labeled Olanzapine.</p>Fórmula:C17H20N4SPureza:98%Cor e Forma:SolidPeso molecular:315.45
