Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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FTI-277
CAS:<p>FTI-277, an FTase inhibitor, blocks H-Ras/K-Ras signaling and HDV infection; mimics Ras CAAX peptide.</p>Fórmula:C22H29N3O3S2Cor e Forma:SolidPeso molecular:447.61Curcumin-d6
CAS:<p>Curcumin D6 (difluoroformylmethane D6) is deuterium-labeled curcumin (Turmeric yellow). Curcumin (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxidant, anti-proliferative and anti-a</p>Fórmula:C21H20O6Pureza:98%Cor e Forma:SolidPeso molecular:374.422Necrostatin 2 S enantiomer
CAS:<p>Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2</p>Fórmula:C13H12ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:277.71Metronidazole-d4
CAS:<p>Metronidazole-d4 is a deuterium labeled compound isotopic tracing.Metronidazole is an antibiotic and antiprotozoal oral and BBB penetration anaerobic bacteria.</p>Fórmula:C6H9N3O3Cor e Forma:SolidPeso molecular:175.18Tegaserod
CAS:<p>Tegaserod is a 5-HT4R agonist and 5-HT2B receptor antagonist with antitumor activity used in the treatment of irritable bowel syndrome (IBS).</p>Fórmula:C16H23N5OPureza:99.20% - 99.89%Cor e Forma:SolidPeso molecular:301.39Thalidomide-O-amido-PEG-C2-NH2
CAS:<p>Thalidomide-based cereblon ligand linked to PEG-C2-NH2 for use in PROTAC E3 ligase conjugates.</p>Fórmula:C19H22N4O7Cor e Forma:SolidPeso molecular:418.4Zardaverine
CAS:<p>Zardaverine (BY 290) is a PDE3/4 inhibitor with anti-hepatocarcinogenic activity and is used in the study of acute renal failure and chronic airflow obstruction</p>Fórmula:C12H10F2N2O3Pureza:99.11%Cor e Forma:SolidPeso molecular:268.22Ulipristal Acetate
CAS:Fórmula:C30H37NO4Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Yellow to Green powder to crystalPeso molecular:475.63NU 9056
CAS:<p>NU 9056 is an effective and selective inhibitor of KAT5 histone acetyltransferase with an IC50 of 2 µM.</p>Fórmula:C6H4N2S4Pureza:95.36% - 97.11%Cor e Forma:SolidPeso molecular:232.37Glucagon-Like Peptide (GLP) II, human
CAS:<p>GLP-2, an intestinal growth factor, may treat various human intestinal diseases.</p>Fórmula:C165H254N44O55SCor e Forma:SolidPeso molecular:3766.2FPA-124
CAS:<p>FPA-124 is a cell-permeable copper complex that acts as a selective Akt (protein kinase B) inhibitor to induce apoptosis in a variety of cancer cell lines.</p>Fórmula:C11H9Cl2CuN3O2SPureza:95.04%Cor e Forma:SolidPeso molecular:381.73Tubastatin A TFA
CAS:<p>Tubastatin A is a potent HDAC6 inhibitor with IC50 of 15 nM.</p>Fórmula:C22H22F3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:449.42Isoscabertopin
CAS:<p>Isoscabertopin has anticancer activity.</p>Fórmula:C20H22O6Pureza:98%Cor e Forma:SolidPeso molecular:358.39Cl-amidine TFA
CAS:<p>Cl-amidine TFA: oral PAD inhibitor, induces cancer cell apoptosis, IC50s: PAD1 - 0.8μM, PAD3 - 6.2μM, PAD4 - 5.9μM.</p>Fórmula:C16H20ClF3N4O4Cor e Forma:SolidPeso molecular:424.8Momelotinib sulfate
CAS:<p>Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.</p>Fórmula:C23H26N6O10S2Pureza:98%Cor e Forma:SolidPeso molecular:610.62PERK-IN-2
CAS:<p>PERK-IN-2 is a potent inhibitor of PERK(IC50 of 0.2 nM).</p>Fórmula:C23H18F3N5OPureza:98%Cor e Forma:SolidPeso molecular:437.42PI-103 Hydrochloride
CAS:<p>PI-103 Hydrochloride is a dual PI3K/Akt and mTOR inhibitor exhibiting nM-level inhibition of p110α, p110β, p110δ, p110γ, DNA-PK, mTORC1, and mTORC2.</p>Fórmula:C19H17ClN4O3Pureza:97.07%Cor e Forma:SolidPeso molecular:384.82Nutlin-3
CAS:Fórmula:C30H30Cl2N4O4Pureza:>95.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:581.49Tubulin inhibitor 1
CAS:Tubulin inhibitor 1 blocks tubulin polymerization, with strong anti-tumor effects, induces apoptosis and G2/M mitotic arrest.Fórmula:C21H24N2O4Pureza:98%Cor e Forma:SolidPeso molecular:368.43PT-262
CAS:<p>PT-262: ROCK inhibitor, causes cytoskeleton change, halts lung cancer cell migration.</p>Fórmula:C14H13ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:276.72Iodoacetyl-LC-Biotin
CAS:<p>Iodoacetyl-LC-Biotin (Iaa-Biotin) is a sulfhydryl-responsive probe that forms irreversible thioether bonds at alkaline pH, label protein cysteines.</p>Fórmula:C18H31IN4O3SPureza:97.47%Cor e Forma:SolidPeso molecular:510.43Batabulin sodium
CAS:<p>Batabulin sodium, an antitumor compound, disrupts microtubules, alters cell shape, halts cell cycle, and induces apoptosis.</p>Fórmula:C13H6F6NNaO3SCor e Forma:SolidPeso molecular:393.24Thalidomide-5,6-F
CAS:<p>Thalidomide-5,6-F, a cereblon ligand for CRBN protein recruitment, forms PROTACs for targeted protein degradation.</p>Fórmula:C13H8F2N2O4Cor e Forma:SolidPeso molecular:294.21Belinostat
CAS:Fórmula:C15H14N2O4SPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:318.35Rapamycin-d3
CAS:<p>Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).</p>Fórmula:C51H79NO13Pureza:98%Cor e Forma:SolidPeso molecular:917.19EIF2α activator 2
CAS:<p>EIF2α activator 2 is an activator of eIF2α phosphorylation, anti-proliferative in SRB, K562, and PBMC cells, suitable for cancer research.</p>Fórmula:C21H20F6N2O2Pureza:98.86%Cor e Forma:SolidPeso molecular:446.39Thalidomide-piperazine-Boc
CAS:<p>Thalidomide-piperazine-Boc is an intermediate utilized for synthesizing BCL6 PROTAC, which targets B-cell lymphoma 6 protein.</p>Fórmula:C22H26N4O6Cor e Forma:SolidPeso molecular:442.46CuATSM
CAS:<p>Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.</p>Fórmula:C8H14CuN6S2Cor e Forma:SolidPeso molecular:321.92Pentagamavunon-1
CAS:<p>PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.</p>Fórmula:C23H24O3Cor e Forma:SolidPeso molecular:348.43Fenobucarb
CAS:<p>Fenobucarb is a broad-spectrum carbamate insecticide and AChE inhibitor. It exhibits neurotoxicity to zebrafish foetal development and induces muscle spasms</p>Fórmula:C12H17NO2Pureza:98.80%Cor e Forma:White CrystalPeso molecular:207.27C8-Ceramide
CAS:<p>C8 Ceramide, a cell-permeable analog, is analog to naturally occur ceramides.</p>Fórmula:C26H51NO3Cor e Forma:SolidPeso molecular:425.69Mycophenolic acid-d3
CAS:<p>Mycophenolic acid-d3 is a derivative that lowers GTP, affects RNA polymerase II transcription, changes polyadenylation, and counters cordyceps.</p>Fórmula:C17H20O6Pureza:98%Cor e Forma:SolidPeso molecular:323.36Pexidartinib hydrochloride
CAS:<p>Pexidartinib HCl is a potent, selective CSF1R and c-Kit inhibitor with IC50s of 20 nM and 10 nM, respectively, showing anti-tumor activity.</p>Fórmula:C20H16Cl2F3N5Cor e Forma:SolidPeso molecular:454.28OTS193320
CAS:<p>OTS193320, an imidazo[1,2-a]pyridine, inhibits SUV39H2, reduces H3K9me3, and induces apoptosis in breast cancer; enhances DOX effects.</p>Fórmula:C28H30ClN5O4Cor e Forma:SolidPeso molecular:536.02Melflufen hydrochloride
CAS:<p>Melflufen HCl: prodrug of Melphalan, has antitumor and antiangiogenic effects, causes DNA damage in MM cells.</p>Fórmula:C24H31Cl3FN3O3Cor e Forma:SolidPeso molecular:534.88Thioridazine
CAS:<p>Thioridazine: an antipsychotic, anti-anxiety drug, blocks dopamine D2, PI3K-Akt-mTOR; halts angiogenesis, kills cancer cells, targets CSCs.</p>Fórmula:C21H26N2S2Cor e Forma:SolidPeso molecular:370.57MM-401 TFA
CAS:<p>MM-401 (TFA), an MLL1 H3K4 methylation inhibitor (IC50 = 0.32 µM), blocks MLL1-WDR5, causing cell cycle arrest and apoptosis, for MLL leukemia studies.</p>Fórmula:C31H47F3N8O7Cor e Forma:SolidPeso molecular:700.755-NIdR
CAS:<p>5-NIdR is a Nucleoside Derivative - Indole nucleoside.</p>Fórmula:C13H14N2O5Cor e Forma:SolidPeso molecular:278.26SB 202190 hydrochloride
CAS:<p>SB 202190 hydrochloride is a p38 MAPK inhibitor that inhibits p38α and p38β2 with selective, cell-permeable, and antitumor ,differentiation to cardiomyocytes.</p>Fórmula:C20H15ClFN3OPureza:99.99%Cor e Forma:SolidPeso molecular:367.8Thalidomide D4
CAS:<p>Thalidomide D4 is a deuterium labeled Thalidomide, has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties.</p>Fórmula:C13H10N2O4Pureza:98%Cor e Forma:SolidPeso molecular:262.25Baohuoside I
CAS:Fórmula:C27H30O10Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow to Green powder to crystalPeso molecular:514.53Alantolactone
CAS:Fórmula:C15H20O2Pureza:>95.0%(GC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:232.32Everolimus-d4
CAS:<p>Everolimus-d4 is a deuterated compound of Everolimus.</p>Fórmula:C53H83NO14Cor e Forma:SolidPeso molecular:962.264TZ9
CAS:<p>TZ9 is a Rad6 inhibitor with anticancer activity.TZ9 inhibits Rad6B-induced ubiquitination of histone H2A.TZ9 induces cell cycle arrest and apoptosis.</p>Fórmula:C17H14N6O4Pureza:99.69%Cor e Forma:SolidPeso molecular:366.33Hematoporphyrin monomethyl ether
CAS:<p>Hematoporphyrin monomethyl ether is a porphyrin photosensitizer that can be used in studies of port wine stains.</p>Fórmula:C35H40N4O6Cor e Forma:SolidPeso molecular:612.72CCW16
CAS:<p>CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand, cysteine reactivity, inducing ferroptosis in AML cells by activating ROS signalling.</p>Fórmula:C22H20ClNO3Pureza:97%Cor e Forma:SolidPeso molecular:381.85Fenvalerate
CAS:<p>Fenvalerate (Evercide 2362) is a protein phosphatase 2B (calcineurin) inhibitor, a synthetic pyrethroid insecticide, that inhibits PP2B-Aα.</p>Fórmula:C25H22ClNO3Pureza:99.62%Peso molecular:419.90KRA-533
CAS:<p>KRA-533 is an effective KRAS agonist that targets the GTP/GDP binding pocket within the KRAS protein, inhibiting GTP cleavage.</p>Fórmula:C13H16BrNO3Pureza:98.11%Cor e Forma:SolidPeso molecular:314.18Dynole 34-2
CAS:<p>Dynole 34-2 is a non-competitive inhibitor of dynamin1 and dynamin2 GTPases that inhibits receptor-mediated endocytosis and synaptic vesicle endocytosis.</p>Fórmula:C25H36N4OPureza:99.61%Cor e Forma:SolidPeso molecular:408.58Fenitrothion
CAS:<p>Fenitrothion (Arbogal) is a insecticide that exhibits reproductive toxicity, inhibits acetylcholinesterase, and is commonly used in agriculture.</p>Fórmula:C9H12NO5PSPureza:95.07%Cor e Forma:Yellow-Brown Liquid Insecticide Against Chewing And Sucking Insects On Rice Orchard Fruits Vegetables Cereals CottonPeso molecular:277.23
