Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5600 produtos de "Apoptose"
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PETCM
CAS:PETCM is a caspase-3 activator and acts as an cytochrome c (cyto c)-dependent manner.Fórmula:C8H8Cl3NOPureza:98%Cor e Forma:SolidPeso molecular:240.51AK-778-XXMU
CAS:<p>AK-778-XXMU is an ID2 antagonist with a KD value of 129 nM.AK-778-XXMU has potential antitumor and anticancer activity and can be used for the study of gliomas.</p>Fórmula:C22H17ClN2O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:392.835Pexidartinib hydrochloride
CAS:<p>Pexidartinib HCl is a potent, selective CSF1R and c-Kit inhibitor with IC50s of 20 nM and 10 nM, respectively, showing anti-tumor activity.</p>Fórmula:C20H16Cl2F3N5Cor e Forma:SolidPeso molecular:454.28Glucagon-Like Peptide (GLP) II, human
CAS:<p>GLP-2, an intestinal growth factor, may treat various human intestinal diseases.</p>Fórmula:C165H254N44O55SCor e Forma:SolidPeso molecular:3766.2Thalidomide-piperazine hydrochloride
CAS:<p>Thalidomide-piperazine HCl may aid leprosy, multiple myeloma research, and developmental biology studies.</p>Fórmula:C17H19ClN4O4Cor e Forma:SolidPeso molecular:378.81Edaravone-d5
CAS:<p>Edaravone, a potent free radical scavenger, prevents MMP-9-induced brain bleeds in rats and has a deuterium variant, Edaravone D5.</p>Fórmula:C10H10N2OPureza:98%Cor e Forma:SolidPeso molecular:179.23Isovalerylcarnitine
CAS:<p>Isovalerylcarnitine (3-methylbutyrylcarnitine) is a selective effective calpain activator that can promote cell apoptosis and is related to isovaleric acidemia.</p>Fórmula:C12H23NO4Pureza:98.24%Cor e Forma:SolidPeso molecular:245.32Lestaurtinib
CAS:<p>Lestaurtinib (CEP 701) is a FLT3 inhibitor that inhibits the phosphorylation of RPTKs and can be used to study leukemia.</p>Fórmula:C26H21N3O4Pureza:99.17%Cor e Forma:Off-White SolidPeso molecular:439.46SC144 hydrochloride
CAS:<p>SC144 hydrochloride: oral gp130 inhibitor, blocks Stat3 and gene expression, triggers apoptosis in ovarian cancer cells.</p>Fórmula:C16H12ClFN6OCor e Forma:SolidPeso molecular:358.76Ezatiostat
CAS:<p>Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.</p>Fórmula:C27H35N3O6SPureza:97.95%Cor e Forma:SolidPeso molecular:529.65Barbadin
CAS:<p>Barbadin is an inhibitor of β-arrestin/β2-adaptin interaction.Barbadin enhances the effects of lorcaserin on weight loss and can be used to study obesity.</p>Fórmula:C19H15N3OSPureza:98.93% - 99.10%Cor e Forma:SolidPeso molecular:333.41Propylparaben sodium
CAS:<p>Propylparaben sodium, a plant-based preservative used in cosmetics, pharma, and food, hinders follicle growth and sperm health.</p>Fórmula:C10H12NaO3Cor e Forma:SolidPeso molecular:203.193Hydrolyzed Fumonisin B1
CAS:<p>Hydrolyzed Fumonisin B1 is the backbone and the main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase.</p>Fórmula:C22H47NO5Pureza:98%Cor e Forma:SolidPeso molecular:405.62Mycophenolic acid-d3
CAS:<p>Mycophenolic acid-d3 is a derivative that lowers GTP, affects RNA polymerase II transcription, changes polyadenylation, and counters cordyceps.</p>Fórmula:C17H20O6Pureza:98%Cor e Forma:SolidPeso molecular:323.36SB 203580
CAS:Fórmula:C21H16FN3OSPureza:>98.0%(HPLC)Cor e Forma:White to Orange to Green powder to crystalPeso molecular:377.44PB28 dihydrochloride
CAS:ZD-6888 Hydrochloride (ZD-6888 HCl) is an angiotensin II antagonist that mediates AII receptor blockade and induces AII-mediated inhibition of renin release.Fórmula:C24H40Cl2N2OPureza:99.97%Cor e Forma:SolidPeso molecular:443.494-PQBH
CAS:<p>4-PQBH is a potent Nur77-binding agent with antitumour activity.4-PQBH is used in the study of hepatocellular carcinoma.</p>Fórmula:C22H17N5OPureza:99.08%Cor e Forma:SolidPeso molecular:367.4PBOX 6
CAS:<p>PBOX 6 is a pyrrolo-1,5-benzoxazepine (PBOX) compound with anticancer and antitumor activity that inhibits the growth of breast cancer cells.</p>Fórmula:C25H20N2O3Pureza:98.18% - 98.71%Cor e Forma:SolidPeso molecular:396.441,4-Dideoxy-1,4-epithio-D-ribitol
CAS:<p>1,4-Dideoxy-1,4-epithio-D-ribitol is a purine nucleoside analog that targets malignant tumors of the inert lymphatic system and possesses a broad spectrum of</p>Fórmula:C5H10O3SPureza:99.76%Cor e Forma:SolidPeso molecular:150.2(Rac)-Hesperetin
CAS:(Rac)-Hesperetin, a racemic flavanone, inhibits human UGT activity and triggers apoptosis via p38 MAPK activation.Fórmula:C16H14O6Cor e Forma:SolidPeso molecular:302.28Palmatine hydroxide
CAS:<p>Palmatine hydroxide: oral IDO-1 inhibitor (IC50: 3-157μM), targets WNV protease, has anti-cancer/viral and neuroprotective properties.</p>Fórmula:C21H23NO5Cor e Forma:SolidPeso molecular:369.412'-Aminoacetophenone
CAS:<p>Compound Fr14273 is a natural product for research related to life sciences. The catalog number is Fr14273 and the CAS number is 551-93-9.</p>Fórmula:C8H9NOPureza:99.88%Cor e Forma:Pale Yellow Solid Solid CrystallinePeso molecular:135.17Melatonin-d4
CAS:<p>Melatonin D5, a deuterium-labeled version of melatonin, is a hormone produced by the pineal gland, known for its role as a selective ATF-6 inhibitor that promotes apoptosis in human hepatoma cells via COX-2 downregulation. Additionally, it activates melatonin receptors and exhibits antioxidative and anti-inflammatory properties.</p>Fórmula:C13H16N2O2Pureza:98%Cor e Forma:SolidPeso molecular:236.3Etoposide Phosphate
CAS:<p>Etoposide Phosphate is a selective and orally active topoisomerase II inhibitor and anticancer chemotherapy drug that apoptosise, the p53, and G2/M</p>Fórmula:C29H33O16PCor e Forma:SolidPeso molecular:668.54M47
CAS:<p>M47 is a selective CRY1 (Cryptochrome 1) degradator that enhances nuclear degradation of CRY1, thereby extending the lifespan of p53 knockout mice.</p>Fórmula:C28H22ClNO4Cor e Forma:SolidPeso molecular:471.93Br-DAPI
CAS:<p>IST5-002 (N6-Benzyladenosine-5'-phosphate) is a Stat5a/b inhibitor with anticancer activity and is used in cancer research.</p>Fórmula:C16H14BrN5Pureza:100%Cor e Forma:SolidPeso molecular:356.22Nafamostat
CAS:<p>Nafamostat is a synthetic serine protease inhibitor and an anticoagulant used in haemodialysis. It induces apoptosis, inhibiting SARS-CoV-2 and COVID-19.</p>Fórmula:C19H17N5O2Pureza:98%Cor e Forma:SolidPeso molecular:347.37Givinostat
CAS:<p>Givinostat (ITF-2357) is a non-selective, orally active HDAC inhibitor capable of inhibiting STAT5 phosphorylation which is antitumour and anti-inflammatory .</p>Fórmula:C24H27N3O4Pureza:98.56%Cor e Forma:SolidPeso molecular:421.5Nutlin-3
CAS:Fórmula:C30H30Cl2N4O4Pureza:>95.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:581.49Amoscanate
CAS:<p>Amoscanate is an antiparasitic agent. It is highly effective in animals against the four major species of schistosomes which infect humans.</p>Fórmula:C13H9N3O2SCor e Forma:SolidPeso molecular:271.29KS100
CAS:<p>KS100 inhibits ALDH1A1, ALDH2, ALDH3A1, boosts ROS, triggers apoptosis, and has anti-cancer properties.</p>Fórmula:C17H14Br3N3O2SPureza:97.05%Cor e Forma:SolidPeso molecular:564.09KT-474
CAS:<p>KT-474 (KYM-001) is a PROTAC degrader targeting IRAK4 with antitumor activity for the study of autoimmune diseases.</p>Fórmula:C44H49F2N11O6Pureza:98.50% - 99.57%Cor e Forma:SolidPeso molecular:865.93SC-560
CAS:Fórmula:C17H12ClF3N2OPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:352.74C8-Ceramide
CAS:<p>C8 Ceramide, a cell-permeable analog, is analog to naturally occur ceramides.</p>Fórmula:C26H51NO3Cor e Forma:SolidPeso molecular:425.69Vitamin E succinate
CAS:<p>Vitamin E succinate (D-alpha-Tocopherol Succinate) is an antioxidant tocopherol with antitumor activity that induces apoptosis.</p>Fórmula:C33H54O5Pureza:99.24%Cor e Forma:SolidPeso molecular:530.78Meisoindigo
CAS:Fórmula:C17H12N2O2Pureza:>98.0%(HPLC)Cor e Forma:Orange to Brown to Dark red powder to crystalPeso molecular:276.30Cystamine
CAS:Cystamine (2,2'-Disulfanediyldiethanamine) is an inhibitor of transglutaminase and inhibits caspase-3 with an IC50 value of 23.6 μM.Fórmula:C4H12N2S2Pureza:99.84%Cor e Forma:SolidPeso molecular:152.28C-DIM 12
CAS:Fórmula:C23H17ClN2Pureza:>98.0%(HPLC)(qNMR)Cor e Forma:Orange to Amber to Dark red powder to crystalinePeso molecular:356.85N-deacetylated BMS-202
CAS:<p>N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interaction with potential anticancer activity for cancer research.</p>Fórmula:C23H27N3O2Pureza:98.13% - 98.13%Cor e Forma:SolidPeso molecular:377.484-[Di(1H-indol-3-yl)methyl]phenol
CAS:Fórmula:C23H18N2OPureza:>97.0%(T)(HPLC)Cor e Forma:White to Light orange to Yellow powder to crystalPeso molecular:338.41GSK-843
CAS:<p>GSK-843 (GSK'843) is a RIP3 inhibitor with analgesic activity, inhibits RIP3 expression, and can be used as an adjunctive treatment for inflammation.</p>Fórmula:C19H15N5S2Pureza:99.18%Cor e Forma:SolidPeso molecular:377.49(S)-Oxiracetam
CAS:<p>(S)-Oxiracetam is a positive allosteric the AMPA receptorsmodulator.</p>Fórmula:C6H10N2O3Cor e Forma:SolidPeso molecular:158.16Condurango glycoside A
CAS:<p>Condurango glycoside A activates p53, induces ROS generation, up-regulates p53 expression, and triggers apoptosis as well as premature senescence associated</p>Fórmula:C53H78O17Cor e Forma:SolidPeso molecular:987.18Sodium catechol sulfate
CAS:<p>Sodium catechol sulfate is a bioactive chemical.</p>Fórmula:C6H4Na2O8S2Pureza:98%Cor e Forma:Light Tan PowderPeso molecular:314.20Degarelix
CAS:<p>Degarelix is a peptide and selective GnRH (human gonadotropin-releasing hormone) receptor antagonist prostate cancer by lowering testosterone levels.</p>Fórmula:C82H103ClN18O16Pureza:99.34%Cor e Forma:SolidPeso molecular:1632.26CuATSM
CAS:<p>Cu/Zn-SOD1 enzyme scavenges radicals; mutations cause ALS. Cu-ATSM, crossing blood-brain barrier, targets hypoxic tissue, may aid ALS mice.</p>Fórmula:C8H14CuN6S2Cor e Forma:SolidPeso molecular:321.92SLC7A11-IN-1
CAS:<p>SLC7A11-IN-1 is an SLC7A11 inhibitor with antiproliferative activity, inhibiting cell invasion and metastasis, useful for research on neurological diseases.</p>Fórmula:C13H17Cl2F3N4O5PtSPureza:95.93%Cor e Forma:SolidPeso molecular:664.35OTS193320
CAS:<p>OTS193320, an imidazo[1,2-a]pyridine, inhibits SUV39H2, reduces H3K9me3, and induces apoptosis in breast cancer; enhances DOX effects.</p>Fórmula:C28H30ClN5O4Cor e Forma:SolidPeso molecular:536.02Wedelolactone
CAS:Fórmula:C16H10O7Pureza:>98.0%(HPLC)Cor e Forma:White to Dark green powder to crystalPeso molecular:314.255-(N,N-Hexamethylene)-amiloride
CAS:<p>5-(N,N-Hexamethylene)-amiloride (5-HMA) is an amiloride derivative that inhibits TRPA1-mediated calcium signaling (IC50: 35 μM). It functions as an inhibitor of the Na+/H+ exchanger (NHE) with Ki values ranging from 0.013 to 2.4 μM for various NHE isoforms. Additionally, 5-HMA blocks ASIC3 channels by 51% at 20 μM.</p>Fórmula:C12H18ClN7OPureza:85.48%Cor e Forma:SolidPeso molecular:311.77
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