Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5599 produtos de "Apoptose"
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Genistein
CAS:<p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>Fórmula:C15H10O5Pureza:98.22% - 99.64%Cor e Forma:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidPeso molecular:270.24Oleic acid
CAS:<p>Oleic acid, a common unsaturated fat, is used in oleates, lotions, and as a pharma solvent.</p>Fórmula:C18H34O2Pureza:97.14% - 99.91%Cor e Forma:Colorless Or Nearly Colorless Liq (Above 5-7 Deg C) Oleic Acid Is A Colorless To Pale Yellow Liquid With A Mild Odor Floats On Water (Uscg 1999)Peso molecular:282.46PRLX-93936
CAS:<p>PRLX-93936 is a selective Ras pathway protein inhibitor that modulates RAS/JNK pathway-associated protein phosphorylation, anticancer activity.</p>Fórmula:C21H24N4O2Cor e Forma:SolidPeso molecular:364.44SJ-172550
CAS:<p>SJ-172550 is a small molecule inhibitor of MDMX (EC50: 5 μM).</p>Fórmula:C22H21ClN2O5Pureza:99.87%Cor e Forma:SolidPeso molecular:428.87PNU-74654
CAS:<p>PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).</p>Fórmula:C19H16N2O3Pureza:97.27%Cor e Forma:SolidPeso molecular:320.34Salidroside
CAS:<p>Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.</p>Fórmula:C14H20O7Pureza:97.81%Cor e Forma:Red-Brown Fine PowderPeso molecular:300.3Elevenostat
CAS:<p>Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.</p>Fórmula:C16H17N3O4Pureza:95% - 96.14%Cor e Forma:SolidPeso molecular:315.32DD1
CAS:<p>DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.</p>Fórmula:C16H14N2O3Pureza:99.57%Cor e Forma:SolidPeso molecular:282.29SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Fórmula:C22H28N2O2Pureza:98.58%Cor e Forma:SolidPeso molecular:352.47D-Saccharic acid 1,4-lactone hydrate
CAS:<p>D-Saccharic acid 1,4-lactone hydrate inhibits β-glucuronidase (IC50=48.4 μM); has anticarcinogenic, detoxifying, antioxidant traits.</p>Fórmula:C17H20ClN3OPureza:99.49% - ≥98%Cor e Forma:SolidPeso molecular:317.81Cyasterone
CAS:<p>Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising</p>Fórmula:C29H44O8Pureza:99.32% - 99.70%Cor e Forma:SolidPeso molecular:520.65Vandetanib trifluoroacetate
CAS:<p>Vandetanib trifluoroacetate: oral VEGFR2/KDR inhibitor, IC50=40nM, also blocks VEGFR3/FLT4 (110nM) and EGFR/HER1 (500nM).</p>Fórmula:C24H25BrF4N4O4Cor e Forma:SolidPeso molecular:589.386Sulindac sodium
CAS:<p>Sulindac (sodium) (MK-231) is an NSAID used for arthritis pain, swelling, gout, and as an immunomodulator in CRC therapy.</p>Fórmula:C20H16FNaO3SCor e Forma:SolidPeso molecular:378.39Formosanin C
CAS:<p>Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity.</p>Fórmula:C51H82O20Pureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:1015.18Vanillyl Alcohol
CAS:<p>Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant and anti-nociceptive activities.</p>Fórmula:C8H10O3Pureza:97.02% - 98.42%Cor e Forma:Crystalline White To Off-White PowderPeso molecular:154.16Pyrogallol
CAS:<p>Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.</p>Fórmula:C6H6O3Pureza:99.88%Cor e Forma:SoildPeso molecular:126.11Trametinib
CAS:<p>Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.</p>Fórmula:C26H23FIN5O4Pureza:98% - 99.96%Cor e Forma:SolidPeso molecular:615.39Thalidomide-5-methyl
CAS:<p>Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand. Thalidomide-5-methyl is used in the recruitment of CRBN protein.</p>Fórmula:C14H12N2O4Pureza:99.48%Cor e Forma:SolidPeso molecular:272.26Taurolidine
CAS:<p>Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity.</p>Fórmula:C7H16N4O4S2Pureza:99.79% - 99.81%Cor e Forma:SolidPeso molecular:284.36DC260126
CAS:<p>DC260126 is a small-molecule antagonist of FFA1 (GPR40)</p>Fórmula:C16H18FNO2SPureza:99.77%Cor e Forma:SolidPeso molecular:307.38Isobutylparaben
CAS:<p>Isobutylparaben is a preservative and preservative insecticide.</p>Fórmula:C11H14O3Pureza:99.36%Cor e Forma:White CreamPeso molecular:194.23Selonsertib
CAS:<p>Selonsertib (GS-4997), an oral ASK1 inhibitor, may have anti-inflammatory, anti-fibrotic, and anti-cancer effects.</p>Fórmula:C24H24FN7OPureza:95.04% - 99.53%Cor e Forma:SolidPeso molecular:445.49Liensinine
CAS:<p>1. Liensinine, a kind of isoquinoline alkaloid, can antagonize the ventricular arrhythmias.</p>Fórmula:C37H42N2O6Pureza:98.92% - 99.93%Cor e Forma:White-Like PowderPeso molecular:610.74BO-264
CAS:<p>BO-264 is a highly potent and orally active inhibitor of transforming acidic coiled-coil 3 (TACC3, IC50 of 188 nM and a Kd of 1.5 nM).</p>Fórmula:C18H19N5O3Pureza:98.03% - 99.81%Cor e Forma:SolidPeso molecular:353.38Trabectedin
CAS:<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Fórmula:C39H43N3O11SPureza:≥98%Cor e Forma:SolidPeso molecular:761.84Mirodenafil dihydrochloride
CAS:<p>Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.</p>Fórmula:C26H39Cl2N5O5SPureza:99.64% - 99.78%Cor e Forma:SolidPeso molecular:604.59Panobinostat lactate
CAS:<p>Panobinostat lactate: potent, non-selective, oral HDAC inhibitor; treats refractory multiple myeloma.</p>Fórmula:C24H29N3O5Cor e Forma:SolidPeso molecular:439.512Tubastatin A Hydrochloride
CAS:<p>Tubastatin A Hydrochloride (TSA HCl) is an effective and specific HDAC6 inhibitor (IC50: 15 nM).</p>Fórmula:C20H21N3O2·HClPureza:97.24% - 99.15%Cor e Forma:SolidPeso molecular:371.86VER-50589
CAS:<p>VER-50589 is a potent HSP90 inhibitor.</p>Fórmula:C19H17ClN2O5Pureza:99.96% - >99.99%Cor e Forma:SolidPeso molecular:388.8Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Fórmula:C28H26N4O3Pureza:99.24% - 99.82%Cor e Forma:Off-White PowderPeso molecular:466.53Laquinimod
CAS:<p>Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral</p>Fórmula:C19H17ClN2O3Pureza:98.42% - 98.84%Cor e Forma:SolidPeso molecular:356.8Topotecan hydrochloride hydrate
CAS:<p>Orally active Topotecan HCl hydrate inhibits Topoisomerase I, blocks G0/G1 & S phases, and induces apoptosis.</p>Fórmula:C23H26ClN3O6Cor e Forma:SolidPeso molecular:475.93AZD1208
CAS:<p>AZD1208 is a novel, orally bioavailable, highly selective PIM kinase inhibitor with single nanomolar potency against all three PIM kinases.</p>Fórmula:C21H21N3O2SPureza:97.24% - 99.83%Cor e Forma:SolidPeso molecular:379.48Resatorvid
CAS:<p>Resatorvid (TAK-242) inhibits TLR4, with IC50s for IL-6, TNF-R, NO at 1.3, 1.9, 1.8 nM respectively.</p>Fórmula:C15H17ClFNO4SPureza:99.31% - >99.99%Cor e Forma:SolidPeso molecular:361.82Quinocetone
CAS:<p>Quinocetone is an animal growth promoter and potential anti-tumor activity.</p>Fórmula:C18H14N2O3Pureza:98.06%Cor e Forma:SolidPeso molecular:306.32Lanreotide acetate
CAS:<p>Lanreotide acetate (BIM 23014 acetate) is a somatostatin analogue with antineoplastic activity, used for carcinoid syndrome</p>Fórmula:C56H73N11O12S2Pureza:>99.99%Cor e Forma:SolidPeso molecular:1156.39dl-Maackiain
CAS:<p>1. dl-Maackiain (Demethylpterocarpin) induces apoptosis and growth suppression 2. MAK1 is the second functional gene cloned from Maackiain detoxification.</p>Fórmula:C16H12O5Pureza:97.36% - 99.89%Cor e Forma:SolidPeso molecular:284.26ICCB-19 hydrochloride
CAS:<p>ICCB-19 hydrochloride (ICCB-19 HCl) is an inhibitor of TRADD (TNFRSF1A Associated Via Death Domain). It binds to a pocket on the TRADD-N.</p>Fórmula:C12H22ClN3OSPureza:99.3%Cor e Forma:SolidPeso molecular:291.84Demethoxycurcumin
CAS:<p>Demethoxycurcumin: antioxidant, anti-inflammatory, anti-proliferative, anti-acanthamoebic, enhances chemo for resistant cancers, inhibits cancer pathways.</p>Fórmula:C20H18O5Pureza:94.54% - 99.86%Cor e Forma:SolidPeso molecular:338.35RIPGBM
CAS:<p>RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).</p>Fórmula:C26H21FN2O3Pureza:99.45%Cor e Forma:SolidPeso molecular:428.45Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Cor e Forma:SolidPeso molecular:532.61Deltamethrin
CAS:<p>Deltamethrin, a pyrethroid insecticide, causes reversible hind limb rigidity in rats and is used for crop protection and disease control.</p>Fórmula:C22H19Br2NO3Pureza:99.25% - 99.85%Cor e Forma:White To Off-White Crystals Or PowderPeso molecular:505.20Euscaphic acid
CAS:<p>Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.</p>Fórmula:C30H48O5Pureza:98.93%Cor e Forma:SolidPeso molecular:488.7C5 Lenalidomide
CAS:<p>C5 Lenalidomide is an chemical weith inconclusive biological activity.</p>Fórmula:C13H13N3O3Pureza:99.4%Cor e Forma:SolidPeso molecular:259.26TrxR1-IN-B19
CAS:<p>TrxR1-IN-B19 (TrxR1 IN B19), a TrxR1 inhibitor, selectively kills gastric cancer cells by a small molecule via targeting TrxR1 and ROS-mediated ER stress</p>Fórmula:C21H22O5Pureza:98.6%Cor e Forma:SolidPeso molecular:354.4Desmorpholinyl Navitoclax-NH-Me
CAS:<p>Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a</p>Fórmula:C44H51ClF3N5O5S3Pureza:99.87%Cor e Forma:SolidPeso molecular:918.55Avadomide HCl
CAS:<p>Avadomide (CC-122), an oral drug, targets CRBN, degrades Ikaros/Aiolos, and mimics interferon, showing antitumor effects in DLBCL.</p>Fórmula:C14H15ClN4O3Cor e Forma:SolidPeso molecular:322.75PS47
CAS:<p>PS-47(PS 47) is an inactive E-isomer of PS48. PS48 is an activator of PDK1.</p>Fórmula:C17H15ClO2Pureza:99.09%Cor e Forma:SolidPeso molecular:286.75NAE-IN-M22
CAS:<p>NAE-IN-M22: Selective, potent NEDD8 enzyme inhibitor; blocks cancer cell growth; induces apoptosis in A549 cells; effective in vivo.</p>Fórmula:C20H24Cl2N2Pureza:97.65%Cor e Forma:SolidPeso molecular:363.32
