Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6223 produtos de "Apoptose"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Acyclovir sodium
CAS:Acyclovir sodium is an antimetabolite. Acyclovir sodium inhibits HSV-specified DNA polymerases and prevents further viral DNA synthesis.Fórmula:C8H10N5NaO3Pureza:99.59% - 99.89%Cor e Forma:SolidPeso molecular:247.19PDK1-IN-RS2
CAS:PDK1-IN-RS2, a PIFtide mimic, selectively inhibits PDK1, blocking S6K1 activation (Kd: 9 μM).Fórmula:C15H9ClN2O2S3Pureza:98%Cor e Forma:SolidPeso molecular:380.89Isoscabertopin
CAS:Isoscabertopin has anticancer activity.Fórmula:C20H22O6Pureza:98%Cor e Forma:SolidPeso molecular:358.394-Benzoyl-L-phenylalanine
CAS:4-Benzoyl-L-phenylalanine is an L-phenylalanine derivative and optically active amino acid.Fórmula:C16H15NO3Pureza:98.01%Cor e Forma:SolidPeso molecular:269.30Almorexant hydrochloride
CAS:Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.Fórmula:C29H32ClF3N2O3Pureza:99.85%Cor e Forma:SolidPeso molecular:549.02Isovalerylcarnitine
CAS:Isovalerylcarnitine (3-methylbutyrylcarnitine) is a selective effective calpain activator that can promote cell apoptosis and is related to isovaleric acidemia.Fórmula:C12H23NO4Pureza:98.24%Cor e Forma:SolidPeso molecular:245.32p,p'-DDD
CAS:TDE is an organochlorine insecticide with slightly irritating to the skin.Fórmula:C14H10Cl4Cor e Forma:Colourless To Off-White CrystalsPeso molecular:320.03BAY 11-7082
CAS:Fórmula:C10H9NO2SPureza:>98.0%(HPLC)(N)Cor e Forma:White to Almost white powder to crystalPeso molecular:207.25SLF
CAS:SLF is a synthetic ligand for FKBP12 and increases Ca2+ efflux and protein synthesis.Fórmula:C30H40N2O6Pureza:99.91%Cor e Forma:SolidPeso molecular:524.65Isoalantolactone
CAS:Fórmula:C15H20O2Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:232.32AZD-5991
CAS:AZD-5991, an antitumor compound, is a highly selective, potent and direct MCL-1 inhibitor, rapid apoptosis by Bak-dependent mitochondrial apoptotic pathway.Fórmula:C35H34ClN5O3S2Pureza:98.08% - 98.95%Cor e Forma:SolidPeso molecular:672.26Ref: TM-T10434
1mg109,00€5mg260,00€1mL*10mM (DMSO)385,00€10mg409,00€25mg717,00€50mg1.018,00€100mg1.378,00€Momelotinib sulfate
CAS:Momelotinib sulfate is an ATP-competitive JAK1/JAK2 inhibitor (IC50: 11 nM/18 nM). It has 10-fold selectivity versus JAK3.Fórmula:C23H26N6O10S2Pureza:98%Cor e Forma:SolidPeso molecular:610.62(Rac)-Apremilast D5
CAS:(Rac)-Apremilast D5 is a deuterium-labeled version of the enantiomer (R)-Apremilast, also known as (R)-CC-10004, which itself is one specific form of ApremilastFórmula:C22H24N2O7SPureza:98%Cor e Forma:SolidPeso molecular:465.53PERK-IN-2
CAS:PERK-IN-2 is a potent inhibitor of PERK(IC50 of 0.2 nM).Fórmula:C23H18F3N5OPureza:98%Cor e Forma:SolidPeso molecular:437.429-Nitrocamptothecin
CAS:Fórmula:C20H15N3O6Pureza:>98.0%(HPLC)Cor e Forma:White to Yellow powder to crystalPeso molecular:393.36N-3-oxo-dodecanoyl-L-Homoserine lactone
CAS:N-3-oxo-dodecanoyl-L-Homoserine lactone (3-oxo-C12-HSL), a quorum-sensing signaling molecule synthesized by P. aeruginosa and specific B. cepacia complex strains [1][2], facilitates bacterial gene expression modulation in response to cell density escalation and triggers IL-8 production in 16HBE human bronchial epithelial cells [3].Fórmula:C16H27NO4Cor e Forma:SolidPeso molecular:297.39PND-1186 hydrochloride
CAS:PND-1186 hydrochloride (VS-4718 hydrochloride) is a highly specific, reversible and potent inhibitor of FAK (IC50: 1.5 nM), which can selectively induceFórmula:C25H27ClF3N5O3Cor e Forma:SolidPeso molecular:537.97Ulipristal Acetate
CAS:Fórmula:C30H37NO4Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Yellow to Green powder to crystalPeso molecular:475.63YZ129
CAS:YZ129, an HSP90-calcineurin-NFAT inhibitor with 820 nM IC50, halts GBM growth, arrests G2/M phase, and induces apoptosis.Fórmula:C19H12N2O2Cor e Forma:SolidPeso molecular:300.31PI-103 Hydrochloride
CAS:PI-103 Hydrochloride is a dual PI3K/Akt and mTOR inhibitor exhibiting nM-level inhibition of p110α, p110β, p110δ, p110γ, DNA-PK, mTORC1, and mTORC2.Fórmula:C19H17ClN4O3Pureza:97.07%Cor e Forma:SolidPeso molecular:384.82GO-203
CAS:GO-203 is a useful organic compound for research related to life sciences. The catalog number is T35351 and the CAS number is 1222186-26-6.Fórmula:C89H171F3N52O21S2Cor e Forma:SolidPeso molecular:2426.81Belinostat
CAS:Fórmula:C15H14N2O4SPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:318.35Rapamycin-d3
CAS:Rapamycin-d3 is the deuterium labeled Rapamycin. Rapamycin is a potent and specific inhibitor of mTOR(IC50 of 0.1 nM in HEK293 cells).Fórmula:C51H79NO13Pureza:98%Cor e Forma:SolidPeso molecular:917.19Cobimetinib hemifumarate
CAS:Cobimetinib hemifumarate is a potent and selective MEK1 inhibitor with an IC50 value of 4.2 nM for MEK1.Fórmula:C46H46F6I2N6O8Cor e Forma:SolidPeso molecular:1178.707Pentagamavunon-1
CAS:PGV-1, an oral Curcumin analog, induces apoptosis by inhibiting COX-2, VEGF, and NF-κB activation.Fórmula:C23H24O3Cor e Forma:SolidPeso molecular:348.43Fenobucarb
CAS:Fenobucarb is a broad-spectrum carbamate insecticide and AChE inhibitor. It exhibits neurotoxicity to zebrafish foetal development and induces muscle spasmsFórmula:C12H17NO2Pureza:98.80%Cor e Forma:White CrystalPeso molecular:207.27C8-Ceramide
CAS:C8 Ceramide, a cell-permeable analog, is analog to naturally occur ceramides.Fórmula:C26H51NO3Cor e Forma:SolidPeso molecular:425.69SC144 hydrochloride
CAS:SC144 hydrochloride: oral gp130 inhibitor, blocks Stat3 and gene expression, triggers apoptosis in ovarian cancer cells.Fórmula:C16H12ClFN6OCor e Forma:SolidPeso molecular:358.76DCVC
CAS:DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.Fórmula:C5H7Cl2NO2SCor e Forma:SolidPeso molecular:216.09Melflufen hydrochloride
CAS:Melflufen HCl: prodrug of Melphalan, has antitumor and antiangiogenic effects, causes DNA damage in MM cells.Fórmula:C24H31Cl3FN3O3Cor e Forma:SolidPeso molecular:534.88Bucladesine calcium
CAS:Bucladesine calcium: PDE inhibitor, boosts cAMP, activates PKA.Fórmula:C36H46CaN10O16P2Cor e Forma:SolidPeso molecular:976.844Alantolactone
CAS:Fórmula:C15H20O2Pureza:>95.0%(GC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:232.32ML-291
CAS:ML291 triggers UPR, causing apoptosis in solid cancers by activating PERK/eIF2a/CHOP pathway and reducing leukemia cells.Fórmula:C16H16ClN3O6SCor e Forma:SolidPeso molecular:413.83Casein Kinase inhibitor A86
CAS:Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α) and also inhibits CDK7 (TFIIH) and CDK9 (P-TEFb). It induces apoptosis in leukemia cells, exhibiting substantial anti-leukemic effects.Fórmula:C18H25FN6Cor e Forma:SolidPeso molecular:344.438Fosfenopril
CAS:Fosfenopril is an ACE inhibitor reducing LPS-induced inflammation via TLR4/NF-κB suppression, used in cardiovascular and anti-inflammatory molecular studies.Fórmula:C23H34NO5PPureza:99.05%Cor e Forma:SolidPeso molecular:435.49(±)-Shikonin
CAS:Fórmula:C16H16O5Pureza:>98.0%(HPLC)Cor e Forma:Orange to Brown powder to crystalPeso molecular:288.30Fenvalerate
CAS:Fenvalerate (Evercide 2362) is a protein phosphatase 2B (calcineurin) inhibitor, a synthetic pyrethroid insecticide, that inhibits PP2B-Aα.Fórmula:C25H22ClNO3Pureza:99.62%Cor e Forma:Clear Yellow Viscous Liquid Fenvalerate Is A Clear Viscious Yellow Liquid With A Mild Odor Used As Broad Spectrum InsecticidePeso molecular:419.90KRA-533
CAS:KRA-533 is an effective KRAS agonist that targets the GTP/GDP binding pocket within the KRAS protein, inhibiting GTP cleavage.Fórmula:C13H16BrNO3Pureza:98.11%Cor e Forma:SolidPeso molecular:314.18Ref: TM-T38411
2mg40,00€5mg58,00€1mL*10mM (DMSO)65,00€10mg90,00€25mg185,00€50mg317,00€100mg530,00€200mg756,00€Fenitrothion
CAS:Fenitrothion (Arbogal) is a insecticide that exhibits reproductive toxicity, inhibits acetylcholinesterase, and is commonly used in agriculture.Fórmula:C9H12NO5PSPureza:95.07%Cor e Forma:Yellow-Brown Liquid Insecticide Against Chewing And Sucking Insects On Rice Orchard Fruits Vegetables Cereals CottonPeso molecular:277.23SU11652
CAS:SU11652 is an effective and competitive receptor tyrosine kinase (RTK) inhibitor, including VEGFR, FGFR, PDGFR, and Kit.Fórmula:C22H27ClN4O2Pureza:99.14%Cor e Forma:SolidPeso molecular:414.93Ibuprofen-d3
CAS:Ibuprofen D3 is a deuterium labeled Ibuprofen. Ibuprofen is a COX-1 and COX-2 inhibitor (IC50s: 13 μM and 370 μM).Fórmula:C13H18O2Cor e Forma:SolidPeso molecular:209.3Metformin-d6 hydrochloride
CAS:Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.Fórmula:C4H12ClN5Pureza:98.1%Cor e Forma:SolidPeso molecular:171.66Monensin sodium salt (Standard)
CAS:Monensin sodium salt (Standard) is the standard substance of Monensin sodium salt, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt (Monensin A sodium salt) causes a marked enlargement of the MVBs and regulates exosome secretionFórmula:C36H61NaO11Peso molecular:692.85Alternariol (Standard)
CAS:Alternariol (Standard) is the standard substance of Alternariol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Alternariol (AOH), a mycotoxin synthesized by Alternaria species, displays numerous therapeutic and biological effects, including phytotoxic, cytotoxic, anti-HIV, anti-cancer, and anti-microbial properties. It functions by inhibiting the catalytic activity of topoisomerase I and II enzymes.Fórmula:C14H10O5Cor e Forma:SolidPeso molecular:258.23SEN177
CAS:SEN177 shows the potential in the research of Huntington's disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].Fórmula:C18H19FN6Cor e Forma:SolidPeso molecular:338.38SLC7A11-IN-1
CAS:SLC7A11-IN-1 is an SLC7A11 inhibitor with antiproliferative activity, inhibiting cell invasion and metastasis, useful for research on neurological diseases.Fórmula:C13H17Cl2F3N4O5PtSPureza:95.93%Cor e Forma:SolidPeso molecular:664.35Tacrolimus-13C-d2
CAS:Tacrolimus-13C-d2 is the 13C and deuterated compound of Tacrolimus.Fórmula:C44H67D2NO12Cor e Forma:SolidPeso molecular:807.02Degarelix
CAS:Degarelix is a peptide and selective GnRH (human gonadotropin-releasing hormone) receptor antagonist prostate cancer by lowering testosterone levels.Fórmula:C82H103ClN18O16Pureza:99.34%Cor e Forma:SolidPeso molecular:1632.26N-deacetylated BMS-202
CAS:N-deacetylated BMS-202 is an inhibitor of PD-1/PD-L1 interaction with potential anticancer activity for cancer research.Fórmula:C23H27N3O2Pureza:98.13% - 99.58%Cor e Forma:SolidPeso molecular:377.48K 858
CAS:Fórmula:C13H15N3O2SPureza:>98.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:277.34
