Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6222 produtos de "Apoptose"
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Afatinib Dimaleate
CAS:Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the EGFR family, with antineoplastic activity.Fórmula:C32H33ClFN5O11Pureza:98.11% - 99.87%Cor e Forma:SolidPeso molecular:718.08Psoralen
CAS:Psoralen (Ficusin) is a furocoumarin that intercalates with DNA, inhibiting DNA synthesis and cell division.
Fórmula:C11H6O3Pureza:99.3% - 99.87%Cor e Forma:Crystals From Ether Crystalline SolidPeso molecular:186.16CM-272
CAS:CM-272 is a dual G9a/DNA methyltransferases (DNMTs) inhibitor.Fórmula:C28H38N4O3Pureza:97.83%Cor e Forma:SolidPeso molecular:478.63Trifloxystrobin
CAS:Trifloxystrobin is a fungicide against R. solani in sugar beets with EC50s: 23.0 μg/L for Daphnia neonates, 1.7 μg/L for embryos.Fórmula:C20H19F3N2O4Pureza:99.49%Cor e Forma:SolidPeso molecular:408.37Mitoxantrone diacetate
CAS:Mitoxantrone diacetate hinders topoisomerase II & PKC, fights tumors & orthopoxviruses (IC50: 8.5μM, EC50: 0.25-0.8μM).Fórmula:C26H36N4O10Cor e Forma:SolidPeso molecular:564.592Siremadlin
CAS:Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.Fórmula:C26H24Cl2N6O4Pureza:98.98% - 99.76%Cor e Forma:SolidPeso molecular:555.41Ref: TM-T5555
1mg55,00€2mg75,00€5mg105,00€1mL*10mM (DMSO)129,00€10mg177,00€25mg319,00€50mg512,00€100mg762,00€Benzoylpaeoniflorin
CAS:1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.Fórmula:C30H32O12Pureza:95.86% - 97.28%Cor e Forma:SolidPeso molecular:584.57Cinchonine monohydrochloride hydrate
CAS:Cinchonine monohydrochloride hydrate: natural antimalarial, inhibits platelet aggregation & cancer cell growth, blocks fat cell formation.Fórmula:C19H25ClN2O2Cor e Forma:SolidPeso molecular:348.878-Bromo-cAMP sodium salt
CAS:8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.Fórmula:C10H10BrN5NaO6PPureza:98% - 99.94%Cor e Forma:Off-White PowderPeso molecular:430.08Dacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Fórmula:C24H25ClFN5O2Pureza:99.4% - 99.72%Cor e Forma:SolidPeso molecular:469.94Ref: TM-T2483
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)74,00€10mg120,00€25mg170,00€50mg215,00€100mg334,00€200mg421,00€500mg692,00€Sodium Demethylcantharidate
CAS:Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.Fórmula:C8H9O5·NaPureza:99.66% - ≥98%Cor e Forma:SolidPeso molecular:208.14Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Fórmula:C47H76O16Pureza:98.76% - 99.92%Cor e Forma:SolidPeso molecular:897.1Ref: TM-T2P2806
1mg46,00€5mg114,00€1mL*10mM (DMSO)161,00€10mg167,00€25mg268,00€50mg408,00€100mg587,00€200mg825,00€Talampanel
CAS:Talampanel (LY-300164), an oral selective AMPA receptor antagonist, exhibits anti-seizure and neuroprotective properties.Fórmula:C19H19N3O3Pureza:98.3%Cor e Forma:SolidPeso molecular:337.37ENMD-1068 hydrochloride
CAS:ENMD-1068 hydrochloride: selective PAR2 antagonist, counters liver fibrosis, hinders endometrial cell growth, and induces apoptosis in studies.Fórmula:C15H30ClN3O2Cor e Forma:SolidPeso molecular:319.87Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFórmula:C42H56F2N8O6Pureza:97.08% - ≥95%Cor e Forma:SolidPeso molecular:806.94Ref: TM-T6007
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)92,00€10mg109,00€25mg172,00€50mg250,00€100mg447,00€Topotecan
CAS:Topotecan (NSC-609669) is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.Fórmula:C23H23N3O5Pureza:96.14% - 98.23%Cor e Forma:Light Yellow Needle Crystal Or Crystalline PowderPeso molecular:421.45DRB
CAS:DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 range of 4-10 μM)
Fórmula:C12H12Cl2N2O4Pureza:99.46% - 99.83%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:319.14Tenovin-6 Hydrochloride
CAS:Tenovin-6 HCl: Inhibits SIRT1 (21µM), SIRT2 (10µM), HDAC8; potent p53 activator.Fórmula:C25H35ClN4O2SPureza:99.36%Cor e Forma:SolidPeso molecular:491.09Ref: TM-T8480
1mg39,00€2mg51,00€5mg70,00€1mL*10mM (DMSO)73,00€10mg88,00€25mg140,00€50mg226,00€100mg376,00€AZD3759 hydrochloride
CAS:AZD3759 hydrochloride is an oral, CNS-penetrant EGFR inhibitor with IC50s of 0.2/0.3/0.2 nM.Fórmula:C22H24Cl2FN5O3Pureza:99.62%Cor e Forma:SolidPeso molecular:496.36Ref: TM-T4249
2mg34,00€5mg46,00€1mL*10mM (DMSO)49,00€10mg62,00€25mg94,00€50mg167,00€100mg265,00€200mg385,00€VR23
CAS:VR23: Potent proteasome inhibitor; IC50: 1 nM trypsin, 50-100 nM chymotrypsin, 3 μM caspase-like.Fórmula:C19H16ClN5O6SPureza:98.99% - 99.22%Cor e Forma:SolidPeso molecular:477.88Emricasan
CAS:Emricasan (IDN-6556) is a pan-caspase inhibitor with irreversible properties.Fórmula:C26H27F4N3O7Pureza:98.13% - 99%Cor e Forma:SolidPeso molecular:569.5Aloperine
CAS:Aloperine exhibits anti-inflammatory, antibacterial, antiviral, and anti-tumor properties.Fórmula:C15H24N2Pureza:98% - 99.88%Cor e Forma:Yellow Crystalline PowderPeso molecular:232.361400W dihydrochloride
CAS:1400W dihydrochloride (N-(3-(Aminomethyl)benzyl)acetamidine) is a highly effective and specific inhibitor of inducible NOS2 (iNOS).Fórmula:C10H17Cl2N3Pureza:98% - 99.94%Cor e Forma:SolidPeso molecular:250.17Ref: TM-T3491
5mg48,00€1mL*10mM (DMSO)50,00€10mg71,00€25mg118,00€50mg207,00€100mg354,00€200mg460,00€500mg747,00€Thalidomide-NH-PEG1-NH2 hydrochloride
CAS:Thalidomide-NH-PEG1-NH2 hydrochloride (4-[(2-(2-Aminoethoxy)ethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl) is a synthetic E3 ligase ligand-Fórmula:C17H21ClN4O5Pureza:97.13%Cor e Forma:SolidPeso molecular:396.83Tetrahydroxyquinone monohydrate
CAS:Anticataract compound; redox-active; forms ROS via semiquinone radical cycle.Fórmula:C6H6O7Cor e Forma:SolidPeso molecular:190.11ISRIB (trans-isomer)
CAS:ISRIB (trans-isomer) is a potent inhibitor of PERK that rescues protein translation and prevents SG formation in the presence of P-eIF2α. Cost effective and quality assured.Fórmula:C22H24Cl2N2O4Pureza:97.86% - 99.27%Cor e Forma:SolidPeso molecular:451.34Thalidomide-O-amido-C6-NH2 hydrochloride
CAS:Thalidomide-O-amido-C6-NH2 HCl, a cereblon ligand-linker for PROTAC synthesis.Fórmula:C21H27ClN4O6Pureza:97.33%Cor e Forma:SolidPeso molecular:466.915Dacarbazine citrate
CAS:Dacarbazine citrate treats lymphatic cancers, malignant melanoma, islet cell carcinoma, and soft tissue sarcoma.Fórmula:C12H18N6O8Cor e Forma:SolidPeso molecular:374.31FOXO4-DRI acetate
FOXO4-DRI acetate is a bioactive chemical.Fórmula:C36H64N14O14SPureza:99.10%Cor e Forma:SolidPeso molecular:5358.06Thalidomide-O-COOH
CAS:Thalidomide-O-COOH is a Cereblon ligand for CRBN protein recruitment and PROTAC construction with a linker.Fórmula:C15H12N2O7Pureza:98% - 98.29%Cor e Forma:SolidPeso molecular:332.27Difurazon hydrochloride
CAS:Difurazon HCl: a mutagenic antibacterial and growth promoter, used for bacillary dysentery in feed.Fórmula:C14H13ClN6O6Pureza:98.51%Cor e Forma:SolidPeso molecular:396.74KRCA-0008
CAS:KRCA-0008 is an effective and specific ALK/Ack1 inhibitor (IC50: 12/4 nM); displays drug-like properties without hERG liability.Fórmula:C30H37ClN8O4Pureza:96.19%Cor e Forma:SolidPeso molecular:609.12Perhexiline
CAS:Perhexiline: oral CPT1/2 inhibitor, limits fat metabolism, crosses BBB, anti-cancer, induces liver cell apoptosis, for cancer/cardio research.Fórmula:C19H35NCor e Forma:SolidPeso molecular:277.49IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Fórmula:C21H21NO4Pureza:98.07% - 98.14%Cor e Forma:SolidPeso molecular:351.4Ref: TM-T8841
1mg77,00€5mg166,00€1mL*10mM (DMSO)178,00€10mg285,00€25mg533,00€50mg763,00€100mg1.054,00€Cystamine dihydrochloride
CAS:Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage.Fórmula:C4H14Cl2N2S2Pureza:98.91% - 99.81%Cor e Forma:White PowderPeso molecular:225.19KX2-361
CAS:KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastomaFórmula:C24H24FN3O2Pureza:99.64% - 99.68%Cor e Forma:SolidPeso molecular:405.46Ref: TM-T9411
1mg77,00€5mg161,00€1mL*10mM (DMSO)172,00€10mg224,00€25mg366,00€50mg515,00€100mg692,00€200mg888,00€Crebanine
CAS:Crebanine mitigates arrhythmias, increases aconitine tolerance in rats, lacks effect on ouabain-induce arrhythmias, and shows anti-cancer properties.Fórmula:C20H21NO4Pureza:99.17% - 99.77%Cor e Forma:SolidPeso molecular:339.39Rabeprazole sodium
CAS:Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.Fórmula:C18H20N3NaO3SPureza:98% - 99.912%Cor e Forma:White Or Off White Crystalline PowderPeso molecular:381.42Desmorpholinyl Navitoclax-NH-Me
CAS:Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a
Fórmula:C44H51ClF3N5O5S3Pureza:99.87%Cor e Forma:SolidPeso molecular:918.55Lercanidipine hydrochloride
CAS:Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.Fórmula:C36H41N3O6·HClPureza:99.86% - 99.91%Cor e Forma:Pale-Yellow PowderPeso molecular:648.194-Oxofenretinide
CAS:4-Oxofenretinide (3-Keto fenretinide) , a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.Fórmula:C26H31NO3Pureza:96.89%Cor e Forma:SolidPeso molecular:405.53Ref: TM-T4189
1mg42,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)90,00€10mg107,00€25mg185,00€50mg278,00€100mg500,00€1-(1-Naphthyl) piperazine hydrochloride
CAS:1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multipleFórmula:C14H17ClN2Pureza:98.27%Cor e Forma:SolidPeso molecular:248.75Bardoxolone Methyl
CAS:Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-Fórmula:C32H43NO4Pureza:97.81% - 99.09%Cor e Forma:SolidPeso molecular:505.69Decursin
CAS:Decursin: potential antiepileptic, hepatoprotective, anti-cancer, anti-amnesic; affects NOX activation, PKCα/MAPK/NF-κB pathways, AChE.Fórmula:C19H20O5Pureza:97.22% - 99.91%Cor e Forma:SolidPeso molecular:328.36Ref: TM-T3S1416
1mg40,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg113,00€25mg245,00€50mg439,00€100mg627,00€500mg1.288,00€Ζ-Stat
CAS:ζ-Stat (NSC37044), a specific and atypical inhibitor of PKC-ζ with an IC50 of 5 μM, demonstrates the ability to inhibit proliferation and induce apoptosis inFórmula:C10H8O10S3Pureza:99.85%Cor e Forma:SolidPeso molecular:384.36Darapladib
CAS:Darapladib (SB-480848) is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with an IC50 value of 0.25 nM.Cost-effective and quality-assured.Fórmula:C36H38F4N4O2SPureza:99.82% - >99.99%Cor e Forma:SolidPeso molecular:666.77Ref: TM-T6109
200mgA consultar1mg42,00€2mg52,00€5mg87,00€1mL*10mM (DMSO)116,00€10mg125,00€25mg180,00€50mg309,00€100mg499,00€GDC-0623
CAS:GDC-0623 (RG 7421) is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.Fórmula:C16H14FIN4O3Pureza:98.95% - 99.02%Cor e Forma:SolidPeso molecular:456.21Ref: TM-T6843
1mg50,00€2mg70,00€5mg113,00€1mL*10mM (DMSO)113,00€10mg177,00€25mg265,00€50mg349,00€100mg580,00€Devimistat
CAS:Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase
Fórmula:C22H28O2S2Pureza:98.06% - 99.24%Cor e Forma:SolidPeso molecular:388.59Diallyl Trisulfide
CAS:Diallyl Trisulfide is an organic polysulfide compound found in garlic that acts as an H2S donor.Fórmula:C6H10S3Pureza:95% - ≥98%Cor e Forma:LiquidPeso molecular:178.34
