Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6223 produtos de "Apoptose"
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BC-1258
CAS:BC-1258 is a unique small molecule F-box/LRR-repeat protein 2 (FBXL2) activator.Fórmula:C22H22N4S2Pureza:97.48% - 99.64%Cor e Forma:SolidPeso molecular:406.57Afimetoran
CAS:Afimetoran (BMS-986256) is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.Fórmula:C26H32N6OPureza:99.81% - 99.94%Cor e Forma:SolidPeso molecular:444.57Ref: TM-T39654
1mg87,00€5mg177,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg492,00€50mg688,00€100mg964,00€Z-VAD-FMK
CAS:Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does notFórmula:C21H28FN3O7Pureza:98.24% - 99.79%Cor e Forma:SolidPeso molecular:453.46Ref: TM-T7020
1mg112,00€5mg231,00€1mL*10mM (DMSO)255,00€10mg394,00€25mg627,00€50mg890,00€100mg1.198,00€200mg1.603,00€(E/Z)-NiCur
CAS:Benzonitrile, 3,3'-[(2-oxo-1,3-cyclohexanediylidene)dimethylidyne]bis- (9CI) is an inhibitor of p53 with an IC50 value of 0.35 μMFórmula:C22H16N2OPureza:99.18%Cor e Forma:SolidPeso molecular:324.38Ref: TM-T9129
1mg49,00€5mg102,00€1mL*10mM (DMSO)105,00€10mg149,00€25mg245,00€50mg354,00€100mg495,00€200mg673,00€Z-DEVD-FMK
CAS:Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,Fórmula:C30H41FN4O12Pureza:96.19% - 99.69%Cor e Forma:SolidPeso molecular:668.66Rebastinib
CAS:DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,
Fórmula:C30H28FN7O3Pureza:99.53% - 99.79%Cor e Forma:SolidPeso molecular:553.59PCI-34051
CAS:PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).Fórmula:C17H16N2O3Pureza:97.219% - 98.29%Cor e Forma:SolidPeso molecular:296.32Ref: TM-T6325
5mg57,00€1mL*10mM (DMSO)63,00€10mg90,00€25mg175,00€50mg334,00€100mg537,00€500mg1.134,00€Notoginsenoside R1
CAS:Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.Fórmula:C47H80O18Pureza:99.69% - 99.91%Cor e Forma:SolidPeso molecular:933.13Ref: TM-T2961
10mg42,00€1mL*10mM (DMSO)43,00€25mg71,00€50mg92,00€100mg145,00€200mg219,00€500mg383,00€Geranylgeraniol
CAS:Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice.Fórmula:C20H34OPureza:99.17% - ≥98%Cor e Forma:SolidPeso molecular:290.48YUM70
CAS:YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.Fórmula:C21H19ClN2O4Pureza:97.25%Cor e Forma:SolidPeso molecular:398.84Ref: TM-T8901
1mg46,00€1mL*10mM (DMSO)90,00€5mg92,00€10mg128,00€25mg250,00€50mg369,00€100mg525,00€200mg710,00€R547
CAS:R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM.Fórmula:C18H21F2N5O4SPureza:90% - 99.64%Cor e Forma:SolidPeso molecular:441.45Ref: TM-T6312
1mg48,00€5mg96,00€1mL*10mM (DMSO)114,00€10mg140,00€25mg254,00€50mg487,00€100mg700,00€200mg973,00€PR-619
CAS:PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor. PR-619 induces endoplasmic reticulum stress and activates autophagy. Cost-effective and quality-assured.Fórmula:C7H5N5S2Pureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:223.28Rigosertib sodium
CAS:Rigosertib sodium (ON-01910), a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.Fórmula:C21H24NNaO8SPureza:98% - 99.37%Cor e Forma:SolidPeso molecular:473.47Panobinostat lactate
CAS:Panobinostat lactate: potent, non-selective, oral HDAC inhibitor; treats refractory multiple myeloma.Fórmula:C24H29N3O5Cor e Forma:SolidPeso molecular:439.512DIM-C-pPhOH
CAS:CDIM8 (DIM-C-pPhOH) opposes NR4A1, halts TGF-β breast cancer migration, induces ROS/ER stress, and mimics Nur77 RNAi in pancreatic cancer.Fórmula:C23H18N2OPureza:98.61% - 99.93%Cor e Forma:SolidPeso molecular:338.4Ref: TM-T4400
2mg42,00€1mL*10mM (DMSO)56,00€5mg62,00€10mg79,00€25mg144,00€50mg215,00€100mg356,00€200mg469,00€Adalimumab
CAS:Adalimumab (anti-TNF-alpha) is the first fully human recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.Pureza:95% - >95.0% (SDS-PAGE)Cor e Forma:LiquidPeso molecular:145.4 kDaSetanaxib
CAS:Setanaxib (GKT137831) is a potent, specific dual NADPH oxidase (NOX1/4) inhibitor.Fórmula:C21H19ClN4O2Pureza:93.468% - 99.31%Cor e Forma:SolidPeso molecular:394.85GIBH-130
CAS:GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.Fórmula:C20H20N6OPureza:99.52%Cor e Forma:SolidPeso molecular:360.41Propylparaben
CAS:Propylparaben (Propyl parahydroxybenzoate) is an antimicrobial agent, preservative, flavouring agentFórmula:C10H12O3Pureza:99.84%Cor e Forma:White Solid CrystallinePeso molecular:180.20Navitoclax
CAS:View and buy Navitoclax from TargetMol.Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2.Cited in 4 publications.Fórmula:C47H55ClF3N5O6S3Pureza:95.82% - >99.99%Cor e Forma:Pale Yellow SolidPeso molecular:974.61Lonicerin
CAS:Lonicerin: antioxidant, anti-arthritic, antifungal; potential for combined fungal arthritis treatment from C. albicans.Fórmula:C27H30O15Pureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:594.52Diethylnorspermine HBr
CAS:DENSPM is a potent polyamine analog that induces SSAT, arrests the cell cycle, and triggers apoptosis in various cancer cells.Fórmula:C13H36Br4N4Cor e Forma:SolidPeso molecular:568.075Trametinib
CAS:Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.Fórmula:C26H23FIN5O4Pureza:98% - 99.96%Cor e Forma:SolidPeso molecular:615.39Tivantinib
CAS:Tivantinib (ARQ 197) is an orally bioavailable small molecule inhibitor of c-Met with potential antineoplastic activity.Fórmula:C23H19N3O2Pureza:98% - 99.41%Cor e Forma:SolidPeso molecular:369.42GSK481
CAS:GSK481 (GSK'481) is a RIP1(Receptor Interacting Protein Kinase1) inhibitor. Inhibition of RIP1 has been shown to hinder cell necrotic death.Fórmula:C21H19N3O4Pureza:98.97%Cor e Forma:SolidPeso molecular:377.39AKN-028 trifluoroacetate
CAS:AKN-028 trifluoroacetate causes cell cycle arrest and lowers Myc genes and tyrosine kinase activity in AML.Fórmula:C19H15F3N6O2Cor e Forma:SolidPeso molecular:416.36Avelumab
CAS:Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.Pureza:95% - 97.17% (SDS-PAGE)Cor e Forma:LiquidPeso molecular:143.8 kDaSelonsertib
CAS:Selonsertib (GS-4997), an oral ASK1 inhibitor, may have anti-inflammatory, anti-fibrotic, and anti-cancer effects.Fórmula:C24H24FN7OPureza:95.04% - 99.53%Cor e Forma:SolidPeso molecular:445.49MIRA-1
CAS:MIRA-1 (WRN Helicase Inhibitor) is a restorer of wild-type p53 conformation/cellular function and selectively inhibits Werner syndrome WRN helicase activityFórmula:C8H9NO4Pureza:99.94%Cor e Forma:SolidPeso molecular:183.16SC144
CAS:SC144 is an orally active small-molecule gp130 inhibitor.Fórmula:C16H11FN6OPureza:99.20%Cor e Forma:SolidPeso molecular:322.3Tylvalosin tartrate
CAS:Tylvalosin tartrate (Acetylisovaleryltylosin Tartrate) is a macrolide antibiotic that can against Gram-positive bacteria.Fórmula:C57H93NO25Pureza:99.25%Cor e Forma:SolidPeso molecular:1192.34Prexasertib
CAS:Prexasertib (LY2606368) is a selective checkpoint kinase 1 (CHK1) inhibitor (Ki 0.9 nM, IC50<1 nM). antitumor activity. High-Quality, Low-Cost!Fórmula:C18H19N7O2Pureza:97.3% - 98.23%Cor e Forma:SolidPeso molecular:365.39Angiotensin II human acetate
CAS:Angiotensin II human acetate (DRVYIHPF acetate) is a vasoconstrictor that mainly acts on the AT1 receptor.Fórmula:C52H75N13O14Pureza:98.89% - 99.78%Cor e Forma:SolidPeso molecular:1106.2CASP3 Activator 1541
CAS:CASP3 Activator 1541 is an activator of the proenzyme forms of caspase-3, and induces cell death.Fórmula:C24H17N3O4Pureza:98.84%Cor e Forma:SolidPeso molecular:411.41Ref: TM-T8652
1mg34,00€5mg71,00€1mL*10mM (DMSO)86,00€10mg105,00€25mg215,00€50mg344,00€100mg532,00€200mg740,00€Sirtinol
CAS:Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).Fórmula:C26H22N2O2Pureza:97.12% - 99.96%Cor e Forma:SolidPeso molecular:394.47Ref: TM-T6671
2mg40,00€5mg55,00€1mL*10mM (DMSO)55,00€10mg88,00€25mg170,00€50mg324,00€100mg482,00€500mg1.063,00€PS 48
CAS:PS 48 has been shown to be a PKB Kinase (PDK1) activator (Kd: 10.3 μM). This compound selectively binds to the PIF-binding pocket of PKB Kinase (PDK1).Fórmula:C17H15ClO2Pureza:99.96% - ≥95%Cor e Forma:SolidPeso molecular:286.75CCCP
CAS:CCCP blocks STING activation, TBK1, IRF3 signaling, and IFN-β production by disrupting MMP.Fórmula:C9H5ClN4Pureza:97.15% - 99.64%Cor e Forma:Yellow To Orange PowderPeso molecular:204.62Trabectedin
CAS:Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.Fórmula:C39H43N3O11SPureza:≥98%Cor e Forma:SolidPeso molecular:761.84tubuloside B
CAS:Tubuloside B from Cistanche salsa stems guards SH-SY5Y cells against TNFalpha-induced apoptosis.Fórmula:C31H38O16Pureza:98.46% - 99.72%Cor e Forma:SolidPeso molecular:666.62Staurosporine
CAS:Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFórmula:C28H26N4O3Pureza:99.24% - 99.82%Cor e Forma:Off-White PowderPeso molecular:466.53Ref: TM-T6680
1mg58,00€2mg82,00€5mg92,00€1mL*10mM (DMSO)103,00€10mg138,00€25mg234,00€50mg380,00€100mg565,00€500mg1.215,00€Kahweol
CAS:Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFórmula:C20H26O3Pureza:99.26% - 99.86%Cor e Forma:Off-White To Yellow SolidPeso molecular:314.42Hypericin
CAS:Hypericin (Cyclosan) is a natural anthraquinone compound. Hypericin exhibits antimicrobial, antiviral, antitumor, and antidepressant effects. Cost-effective and quality-assured.Fórmula:C30H16O8Pureza:98.90% - ≥98%Cor e Forma:Red-Coloured Anthraquinone-DerivativePeso molecular:504.44Ref: TM-T6S0923
1mg54,00€5mg120,00€1mL*10mM (DMSO)133,00€10mg172,00€25mg341,00€50mg504,00€100mg705,00€500mg1.431,00€C25-140
CAS:C25-140 is a small-molecule inhibitor of TRAF6-Ubc13.Fórmula:C26H31N7OPureza:98.81%Cor e Forma:SolidPeso molecular:457.57Deoxypodophyllotoxin
CAS:Deoxypodophyllotoxin is cytotoxic, antineoplastic, anti-tumor, anti-angiogenic, antiviral, and anti-inflammatory.Fórmula:C22H22O7Pureza:99.65% - 99.93%Cor e Forma:SolidPeso molecular:398.413-O-Methylgallic acid
CAS:3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins andFórmula:C8H8O5Pureza:99.56%Cor e Forma:SolidPeso molecular:184.15ISOGINKGETIN
CAS:ISOGINKGETIN (4',4'''-Dimethylamentoflavone), a compound derived from the leaves of Ginkgo biloba, to up-regulate adiponectin secretion.Fórmula:C32H22O10Pureza:98% - 99.75%Cor e Forma:SolidPeso molecular:566.51SCR130
CAS:SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。Fórmula:C19H13Cl2N3O2SPureza:98.9%Cor e Forma:SolidPeso molecular:418.3iCRT3
CAS:iCRT3 is a Wnt and β-catenin-responsive transcription inhibitor.Fórmula:C23H26N2O2SPureza:98.32% - 98.47%Cor e Forma:SolidPeso molecular:394.53
