Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5593 produtos de "Apoptose"
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PNU-74654
CAS:<p>PNU 74654 blocks β-catenin/Tcf4, disrupting Wnt signaling (Kd = 450 nM).</p>Fórmula:C19H16N2O3Pureza:97.27%Cor e Forma:SolidPeso molecular:320.34TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Cor e Forma:SolidPeso molecular:588.07SB 202190
CAS:<p>SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably.</p>Fórmula:C20H14FN3OPureza:98% - 99.84%Cor e Forma:Pale YellowPeso molecular:331.34Rosmarinic acid
CAS:<p>Rosmarinic acid (Labiatenic acid) is widely found in plants and has antioxidant, anti-inflammatory, and antibacterial activities.</p>Fórmula:C18H16O8Pureza:98.88% - 99.73%Cor e Forma:Brown Fine PowderPeso molecular:360.31SRS11-92
CAS:<p>SRS11-92 (AA9) is a ferroptosis inhibitor and a derivative of ferrostatin-1</p>Fórmula:C22H28N2O2Pureza:98.58%Cor e Forma:SolidPeso molecular:352.47Millepachine
CAS:<p>Millepachine is a natural product found in the Chinese herbal medicine with strong antitumor effects against numerous human cancer cells.</p>Fórmula:C22H22O4Pureza:99.73%Cor e Forma:SolidPeso molecular:350.41Tubeimoside I
CAS:<p>Tubeimoside I (Tubeimoside-1)(Lobatoside-H) is an extract from Chinese herbal medicine Bolbostemma paniculatum (MAXIM).</p>Fórmula:C63H98O29Pureza:98.89% - 99.94%Cor e Forma:SolidPeso molecular:1319.43Pyrogallol
CAS:<p>Pyrogallol (Piral) is a white crystalline powder and a powerful reducing agent prepared by heating gallic acid.</p>Fórmula:C6H6O3Pureza:99.88%Cor e Forma:SoildPeso molecular:126.11NVP 231
CAS:<p>NVP-231 is a potent, specific and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits ceramide binding to CerK.</p>Fórmula:C25H25N3O2SPureza:99.16% - ≥95%Cor e Forma:SolidPeso molecular:431.55Y-27632 dihydrochloride
CAS:<p>View and buy Y-27632 dihydrochloride from TargetMol.Y-27632 is a selective inhibitor of ROCKs.Cited in 10 publications.</p>Fórmula:C14H21N3O·2HClPureza:97.96% - 99.98%Cor e Forma:SolidPeso molecular:320.26Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Fórmula:C23H22ClNO2Pureza:99.25%Cor e Forma:Yellowish SolidPeso molecular:379.88NSC 15364
CAS:<p>NSC 15364 (1,3-Bis(4-aminophenyl)urea) can be used for screening of ALR inhibitors by detection of hydrogen peroxide production Measured in Biochemical System.</p>Fórmula:C13H14N4OPureza:98.67%Cor e Forma:SolidPeso molecular:242.28Trabectedin
CAS:<p>Trabectedin (Ecteinascidin 743) has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research.</p>Fórmula:C39H43N3O11SPureza:≥98%Cor e Forma:SolidPeso molecular:761.84Mirodenafil dihydrochloride
CAS:<p>Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.</p>Fórmula:C26H39Cl2N5O5SPureza:99.64% - 99.78%Cor e Forma:SolidPeso molecular:604.59Sinomenine
CAS:<p>Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.</p>Fórmula:C19H23NO4Pureza:99.02% - 99.73%Cor e Forma:White PowderPeso molecular:329.39Tacedinaline
CAS:<p>Tacedinaline (CI994) is a selective class I HDAC inhibitor with potential antineoplastic activity.</p>Fórmula:C15H15N3O2Pureza:96.83% - 99.15%Cor e Forma:WhitePeso molecular:269.3W-7 hydrochloride
CAS:<p>W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride</p>Fórmula:C16H22Cl2N2O2SPureza:99.63%Cor e Forma:White Crystalline SolidPeso molecular:377.32Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Cor e Forma:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Cysteamine hydrochloride
CAS:<p>Cysteamine hydrochloride (Thioethanolamine Hydrochloride) is an agent for the treatment of nephropathic cystinosis and an antioxidant.</p>Fórmula:C2H7NS·HClPureza:99.34% - 99.87%Cor e Forma:White Crystalline Powder With A Strong And Disagreeable SmellPeso molecular:113.61Otenaproxesul
CAS:<p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>Fórmula:C21H19NO3SPureza:98.76% - 99.13%Cor e Forma:SolidPeso molecular:365.45Nivolumab
CAS:<p>Nivolumab is a monoclonal antibody, a humanized IgG4 antibody to PD-1. Nivolumab has antitumor activity. Cost-effective and quality-assured.</p>Pureza:98% - 98%Cor e Forma:LiquidPeso molecular:146 kDaPembrolizumab
CAS:<p>Pembrolizumab (MK-3475) is a humanized monoclonal antibody.Cost-effective and quality-assured.</p>Pureza:95% - 99.70%Cor e Forma:LiquidPeso molecular:149 kDaEGFR-IN-12
CAS:<p>EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.</p>Fórmula:C21H18F3N5OPureza:98.3% - 99.76%Cor e Forma:SolidPeso molecular:413.4HJC0152 hydrochloride
CAS:<p>HJC0152 hydrochloride (HJC0152) is a signal transducer and activator of transcription 3 (STAT3) inhibitor.</p>Fórmula:C15H14Cl3N3O4Pureza:99.01% - 99.06%Cor e Forma:SolidPeso molecular:406.64IITZ-01
CAS:<p>IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)</p>Fórmula:C26H23FN8OPureza:99.31%Cor e Forma:SolidPeso molecular:482.513-Nitropropanoic acid
CAS:<p>3-Nitropropanoic acid (Bovinocidin) is an irreversible inhibitor of succinate dehydrogenase.</p>Fórmula:C3H5NO4Pureza:98.35% - 99.94%Cor e Forma:Crystals From Chloroform Physical Description Golden Crystals (From Chloroform) (Ntp 1992)Peso molecular:119.08TM5441
CAS:<p>TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.</p>Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Cor e Forma:SolidPeso molecular:428.82Angiotensin II human
CAS:<p>Angiotensin II acts on AT1/AT2 receptors, 30% similar seven-transmembrane glycoproteins, converted from Ang I by ACE.</p>Fórmula:C50H71N13O12Pureza:95% - >99.99%Cor e Forma:SolidPeso molecular:1046.18McMMAF
CAS:<p>McMMAF is a protective group-conjugated MMAF.</p>Fórmula:C49H76N6O11Pureza:99.65% - >99.99%Cor e Forma:SolidPeso molecular:925.16TASIN-1
CAS:<p>TASIN-1 is a small molecule inhibitor of mutant adenomatous polyposis coli (APC).</p>Fórmula:C18H28N2O3SPureza:99.86%Cor e Forma:SolidPeso molecular:352.49Candesartan Cilexetil
CAS:<p>Candesartan Cilexetil, an angiotensin II blocker (IC50: 0.26 nM), turns to candesartan in the body, which dilates blood vessels by hindering AT1.</p>Fórmula:C33H34N6O6Pureza:98.22% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:610.66Oprozomib
CAS:<p>Oprozomib inhibits 20S proteasome β5/LMP7, is orally available, and may have cancer-fighting properties. IC50: β5 - 36 nM; LMP7 - 82 nM.</p>Fórmula:C25H32N4O7SPureza:98% - 99.87%Cor e Forma:SolidPeso molecular:532.61NVP-ADW742
CAS:<p>NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl</p>Fórmula:C28H31N5OPureza:96.14% - 98.70%Cor e Forma:SolidPeso molecular:453.58Pevonedistat
CAS:<p>Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM).</p>Fórmula:C21H25N5O4SPureza:95% - 99.92%Cor e Forma:SolidPeso molecular:443.52TASIN-1 Hydrochloride
CAS:<p>TASIN-1 Hydrochloride (TASIN-1 HCl) is a selective inhibitor of truncated APC that acts by selectively killing colorectal cancer cells that express truncated</p>Fórmula:C18H29ClN2O3SPureza:99.94%Cor e Forma:SolidPeso molecular:388.95Isosorbide Mononitrate
CAS:<p>Isosorbide Mononitrate (Corangin) is a Nitrate Vasodilator, dilating the blood vessels so as to reduce the blood pressure.</p>Fórmula:C6H9NO6Pureza:98.16%Cor e Forma:Isosorbide-5-Mononitrate Is A Crystalline Solid It Is Very Flammable And May Be Toxic By IngestionPeso molecular:191.14Parcetasal
CAS:<p>Parcetasal (MR-897) is a non-steroidal anti-inflammatory agent that can be used in pain relief studies.</p>Fórmula:C17H15NO5Pureza:99.07%Cor e Forma:SolidPeso molecular:313.3TPCK
CAS:<p>TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis</p>Fórmula:C17H18ClNO3SPureza:97.33%Cor e Forma:PowderPeso molecular:351.85PX-12
CAS:<p>PX-12, a Trx-1 inhibitor, promotes apoptosis, reduces HIF-1α/VEGF, and inhibits tumor growth, suggesting use in advanced cancer therapy.</p>Fórmula:C7H12N2S2Pureza:98% - 99.21%Cor e Forma:SolidPeso molecular:188.31Fluazinam
CAS:<p>Fluazinam: a pyridinamine fungicide, broad-spectrum, strongly inhibits S. sclerotiorum mycelial growth.</p>Fórmula:C13H4Cl2F6N4O4Pureza:98% - 99.7%Cor e Forma:Light Yellow CrystalsPeso molecular:465.09Tenilsetam
CAS:<p>Tenilsetam: an endonuclease, nootropic, AGE inhibitor potential for Alzheimer's.</p>Fórmula:C8H10N2OSPureza:99.52%Cor e Forma:SolidPeso molecular:182.244-IBP
CAS:<p>4-IBP is a selective σ1 agonist with a high level of affinity for the σ1 receptor (Ki = 1.7 nM) and a moderate affinity for the σ2 receptor (Ki = 25.2 nM) .</p>Fórmula:C19H21IN2OPureza:98.99%Cor e Forma:SolidPeso molecular:420.29Lubiprostone
CAS:<p>Lubiprostone (RU-0211), an activator of ClC-2 chloride channels, is used in the therapy of idiopathic chronic constipation.</p>Fórmula:C20H32F2O5Pureza:97.31% - 98.54%Cor e Forma:White Odorless Crystals Or Crystalline PowderPeso molecular:390.46RH01687
CAS:<p>RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress.</p>Fórmula:C12H9ClN6O2SPureza:97.93%Cor e Forma:SolidPeso molecular:336.76Clodronic acid disodium salt
CAS:<p>Clodronic acid disodium salt (Lodronate), a bisphosphonate, is a potent antiosteolytic agent which inhibits bone resorption.</p>Fórmula:CH4Cl2O6P0·2NaPureza:>99.99% - ≥98%Cor e Forma:White SolidPeso molecular:288.86Sodium benzoate
CAS:<p>Sodium benzoate (Benzoic acid sodium salt) is a D-Amino Acid Oxidase Inhibitor.Sodium Benzoate is a Food Preservative.</p>Fórmula:C7H5NaO2Pureza:99.72%Cor e Forma:White Solid CrystallinePeso molecular:144.10HX 531
CAS:<p>HX 531 is a RXR antagonist (IC50 of 18 nM).Cost-effective and quality-assured.</p>Fórmula:C29H29N3O4Pureza:98.59% - 99.86%Cor e Forma:SolidPeso molecular:483.563-hydroxy-3-phenylpentanamide
CAS:<p>Chiral 3-hydroxy-3-phenylpentanamide: neuroprotective, may treat anxiety/depression/addiction, anticancer.</p>Fórmula:C11H15NO2Pureza:98.42%Cor e Forma:SolidPeso molecular:193.24Ceftiofur
CAS:<p>Ceftiofur is a semisynthetic antibiotic, with activity against various gram-positive/negative, anaerobic and aerobic bacteria encountered by domestic animals.</p>Fórmula:C19H17N5O7S3Pureza:98.26%Cor e Forma:SolidPeso molecular:523.56Epoxiconazole
CAS:<p>Epoxiconazole (BAS-480F) is a 14-α demethylase inhibitor. It inhibits ergosterol synthesis and fungal cell wall formation.</p>Fórmula:C17H13ClFN3OPureza:98.57%Cor e Forma:Solid PowderPeso molecular:329.76
