Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5600 produtos de "Apoptose"
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GSK2801
CAS:<p>GSK2801 is an effective, specific and cell active acetyl-lysine competitive inhibitor of BAZ2A(Kd: 136 nM) and BAZ2B(Kd: 257 nM) bromodomains.</p>Fórmula:C20H21NO4SPureza:97.78% - 99.45%Cor e Forma:SolidPeso molecular:371.45CCCP
CAS:<p>CCCP blocks STING activation, TBK1, IRF3 signaling, and IFN-β production by disrupting MMP.</p>Fórmula:C9H5ClN4Pureza:97.15% - 99.64%Cor e Forma:Yellow To Orange PowderPeso molecular:204.62NS-1619
CAS:NS1619 have cardio-protective effects after ischemia-reperfusion injury.Fórmula:C15H8F6N2O2Pureza:97.66% - 98%Cor e Forma:SolidPeso molecular:362.23Quinidine sulfate dihydrate
CAS:<p>Quinidine sulfate dihydrate (Pitayine Sodium) is a potent and selective cytochrome P450db inhibitor</p>Fórmula:C40H54N4O10SPureza:99.85%Cor e Forma:White To Light Yellow Crystal PowdePeso molecular:782.9IMT1
CAS:<p>IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.</p>Fórmula:C21H21NO4Pureza:98.07% - 98.14%Cor e Forma:SolidPeso molecular:351.4Rilmenidine hemifumarate
CAS:<p>Rilmenidine hemifumarate (S-3341 hemifumarate) is an I1 imidazoline receptor and α2-adrenergic receptor agonist that induces autophagy.</p>Fórmula:C10H16N2OC4H4O4Pureza:98.14%Cor e Forma:SolidPeso molecular:238.28Cystamine dihydrochloride
CAS:<p>Cystamine dihydrochloride is a radiation-protective agent. It also protects against carbon tetrachloride liver damage.</p>Fórmula:C4H14Cl2N2S2Pureza:98.91% - 99.81%Cor e Forma:White PowderPeso molecular:225.19Talampanel
CAS:<p>Talampanel (LY-300164), an oral selective AMPA receptor antagonist, exhibits anti-seizure and neuroprotective properties.</p>Fórmula:C19H19N3O3Pureza:98.3%Cor e Forma:SolidPeso molecular:337.37KX2-361
CAS:<p>KX2-361 is a orally bioavailable small molecule dual Src/tubulin inhibitor that provides long term survival in a murine model of glioblastoma</p>Fórmula:C24H24FN3O2Pureza:99.64% - 99.68%Cor e Forma:SolidPeso molecular:405.46Buparlisib
CAS:<p>Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).</p>Fórmula:C18H21F3N6O2Pureza:95.32% - 98.45%Cor e Forma:SolidPeso molecular:410.39OSU-T315
CAS:<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Fórmula:C30H30F3N5OPureza:98.69%Cor e Forma:SolidPeso molecular:533.59Pomolic acid
CAS:<p>Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-</p>Fórmula:C30H48O4Pureza:96.84% - 99.79%Cor e Forma:SolidPeso molecular:472.7Oleuropein
CAS:<p>Oleuropein is an antioxidant polyphenol isolated from olive leaf.</p>Fórmula:C25H32O13Pureza:98% - 99.95%Cor e Forma:Brown PowderPeso molecular:540.51Maduramicin ammonium
CAS:<p>Maduramicin ammonium (Maduramycin Ammonium) is an anticoccidial agent for the the treatment of Eimeria spp., E.</p>Fórmula:C47H83NO17Pureza:99.83%Cor e Forma:White Crystalline PowderPeso molecular:934.20Tauroursodeoxycholate sodium
CAS:<p>Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.</p>Fórmula:C26H44NNaO6SPureza:97.90%Cor e Forma:SolidPeso molecular:521.69Tetramethylcurcumin
CAS:<p>Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also</p>Fórmula:C25H28O6Pureza:97.69% - 99.94%Cor e Forma:SolidPeso molecular:424.49Trigonelline
CAS:<p>Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.</p>Fórmula:C7H7NO2Pureza:97.585% - 99.49%Cor e Forma:Prisms Aqueous From Alcohol + Water SolidPeso molecular:137.14INH6
CAS:<p>INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1/Nek2 interaction and induces chromosome mis-alignment.</p>Fórmula:C19H18N2OSPureza:98.81%Cor e Forma:SolidPeso molecular:322.42β-mangostin
CAS:<p>β-Mangostin: a xanthone in Cratoxylum arborescens, fights bacteria, malaria, tuberculosis (MIC 6.25μg/mL), and cancer.</p>Fórmula:C25H28O6Pureza:98.01% - 99.69%Cor e Forma:Faintly Yellow PowderPeso molecular:424.49Z-VAD(OMe)-FMK
CAS:<p>View and buy Z-VAD(OMe)-FMK from TargetMol.Z-VAD(OMe)-FMK is a cell-permeable and irreversible pan-caspase inhibitor.Cited in 10 publications.</p>Fórmula:C22H30FN3O7Pureza:95.92% - 99.71%Cor e Forma:SolidPeso molecular:467.49PD0166285
CAS:<p>PD0166285 is a potent Wee1 and Chk1 inhibitor with activity at nanomolar concentrations.PD0166285 is a novel G2 checkpoint abrogator.</p>Fórmula:C26H27Cl2N5O2Pureza:99.23%Cor e Forma:SolidPeso molecular:512.43D-Pantothenic acid sodium
CAS:<p>D-Pantothenic acid sodium, a sodium salt of D-pantothenate, is a vital B5 derivative, aiding fat, carb, and amino acid oxidation.</p>Fórmula:C9H16NNaO5Pureza:97.98%Cor e Forma:White PowderPeso molecular:241.22Avadomide
CAS:<p>Avadomide (CC 122) is an orally available pleiotropic pathway modulator with potential antineoplastic activity.</p>Fórmula:C14H14N4O3Pureza:99.56%Cor e Forma:SolidPeso molecular:286.29Pemetrexed disodium hemipenta hydrate
CAS:<p>Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT.</p>Fórmula:C20H21N5O6·2NaH2OPureza:98.76%Cor e Forma:SolidPeso molecular:518.43Ethoxysanguinarine
CAS:<p>Ethoxysanguinarine inhibits HuAChE and HuBuChE with IC50s of 0.83 and 4.20 μM, respectively.</p>Fórmula:C22H19NO5Pureza:99.24% - 99.48%Cor e Forma:SolidPeso molecular:377.39Volasertib trihydrochloride
CAS:Volasertib (BI 6727), a potent PLK1 inhibitor (IC50: 0.87 nM), also targets PLK2 and PLK3, causes mitotic arrest, apoptosis, and anticancer effects.Fórmula:C34H53Cl3N8O3Cor e Forma:SolidPeso molecular:728.2Desmorpholinyl Navitoclax-NH-Me
CAS:<p>Desmorpholinyl Navitoclax-NH-Me (Desmorpholinyl ABT-263-NH-Me) is a Bcl-xL inhibitor, which can be employed alongside a CRBN ligand to synthesize XZ739, a</p>Fórmula:C44H51ClF3N5O5S3Pureza:99.87%Cor e Forma:SolidPeso molecular:918.55Lercanidipine hydrochloride
CAS:<p>Lercanidipine hydrochloride (Corifeo) is a calcium channel blocker of the dihydropyridine class.</p>Fórmula:C36H41N3O6·HClPureza:99.86% - 99.91%Cor e Forma:Pale-Yellow PowderPeso molecular:648.194-Oxofenretinide
CAS:<p>4-Oxofenretinide (3-Keto fenretinide) , a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.</p>Fórmula:C26H31NO3Pureza:96.89%Cor e Forma:SolidPeso molecular:405.53Z-DEVD-FMK
CAS:<p>Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7,</p>Fórmula:C30H41FN4O12Pureza:96.19% - 99.69%Cor e Forma:SolidPeso molecular:668.661-(1-Naphthyl) piperazine hydrochloride
CAS:<p>1-(1-Naphthyl) piperazine hydrochloride (1-naphthalen-1-ylpiperazine hydrochloride) is a serotonergic ligand which could bind nonselectively with multiple</p>Fórmula:C14H17ClN2Pureza:98.27%Cor e Forma:SolidPeso molecular:248.75Bardoxolone Methyl
CAS:<p>Bardoxolone Methyl (TP-155) is a synthetic triterpenoid that acts as an activator of the Nrf2 pathway and an inhibitor of the NF-κB pathway with potential anti-</p>Fórmula:C32H43NO4Pureza:97.81% - 99.09%Cor e Forma:SolidPeso molecular:505.69FLLL32
CAS:<p>FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM).</p>Fórmula:C28H32O6Pureza:97% - 97.90%Cor e Forma:SolidPeso molecular:464.55Chrysosplenol D
CAS:<p>Chrysosplenol D, an efflux pump inhibitor that can potentiate the activity of commercially important antibiotics and antimalarials.</p>Fórmula:C18H16O8Pureza:97.87% - 99.98%Cor e Forma:SolidPeso molecular:360.31Melatonin
CAS:<p>Melatonin (Melatonine) is a natural hormone that activates melatonin receptors. Melatonin regulates the biological clock. Cost-effective and quality-assured.</p>Fórmula:C13H16N2O2Pureza:98% - 99.89%Cor e Forma:Pale Yellow Leaflets From Benzene SolidPeso molecular:232.28NUN82647
CAS:<p>NUN82647 (CU-242) is an Inhibitor of cell cycle at G2 phase, and apoptosis inducer.</p>Fórmula:C15H13N3O2SPureza:98.91%Cor e Forma:SolidPeso molecular:299.35BIX01294 (hydrochloride hydrate)
CAS:<p>BIX01294 inhibits G9a HMTase (IC50=1.7μM), less effective on GLP, and aids in induced pluripotent stem cell generation.</p>Fórmula:C28H43Cl3N6O3Cor e Forma:SolidPeso molecular:618.04SIRT7 inhibitor 97491
CAS:<p>SIRT7 inhibitor 97491 is an HDAC inhibitor with high specificity for SIRT7 (IC50 = 325 nM). SIRT7 inhibitor 97491 promotes apoptosis through caspase pathway.</p>Fórmula:C15H12ClN3OPureza:99.79%Cor e Forma:SolidPeso molecular:285.73Mycophenolic acid sodium
CAS:<p>Mycophenolic acid sodium inhibits IMPDH with EC50 of 0.24 μM, has antiviral, immunosuppressive, antiangiogenic, and antitumor properties.</p>Fórmula:C17H19NaO6Cor e Forma:SolidPeso molecular:342.323L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Fórmula:C5H9NO4Pureza:99.14% - 99.55%Cor e Forma:White Solid CrystallinePeso molecular:147.13RIPGBM
CAS:<p>RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).</p>Fórmula:C26H21FN2O3Pureza:99.45%Cor e Forma:SolidPeso molecular:428.45Tandutinib hydrochloride
CAS:<p>Tandutinib hydrochloride: FLT3 inhibitor (IC50 0.22 μM), targets c-Kit, PDGFR, treats AML, crosses blood-brain barrier.</p>Fórmula:C31H43ClN6O4Cor e Forma:SolidPeso molecular:599.16Phenoxyethanol
CAS:<p>Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.</p>Fórmula:C8H10O2Pureza:99.47%Cor e Forma:Clear To Practically Clear Colourless LiquidPeso molecular:138.16Quercetin Dihydrate
CAS:<p>Quercetin Dihydrate (Sophoretin) is a flavonoid natural product that activates or inhibits the activity of many proteins. It activates SIRT1 and inhibits PI3K.</p>Fórmula:C15H10O7·2H2OPureza:97.77%Cor e Forma:Yellow SolidPeso molecular:338.27Puromycin aminonucleoside
CAS:<p>Puromycin aminonucleoside (NSC-3056) increases podocyte permeability by modulating ZO-1 in an oxidative stress-dependent manner.</p>Fórmula:C12H18N6O3Pureza:99.85% - 99.9%Cor e Forma:SolidPeso molecular:294.31Dipyrithione
CAS:<p>Dipyrithione appears to have novel cytotoxicity and potent broad-spectrum antitumor activity</p>Fórmula:C10H8N2O2S2Pureza:99.9%Cor e Forma:Beige Crystalline PowderPeso molecular:252.31Shield-1
CAS:<p>Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP).Cost-effective and quality-assured.</p>Fórmula:C42H56N2O10Pureza:99.08%Cor e Forma:SolidPeso molecular:748.9Nocodazole
CAS:<p>Nocodazole: synthetic microtubule polymerization blocker, also impedes Abl with low IC50; binds to beta-tubulin.</p>Fórmula:C14H11N3O3SPureza:98% - 99.91%Cor e Forma:Physical Description White Powder (Ntp 1992)Peso molecular:301.32Z-VAD-FMK
CAS:<p>Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases.Z-VAD-FMK binds to activated caspases and inhibits apoptosis.Z-VAD-FMK does not</p>Fórmula:C21H28FN3O7Pureza:98.24% - 99.79%Cor e Forma:SolidPeso molecular:453.46
