Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(1 produtos)
- Caspase(154 produtos)
- FOXO1(2 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(134 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(17 produtos)
- Survivina(14 produtos)
- TNF(93 produtos)
- c-RET(61 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 6223 produtos de "Apoptose"
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Siremadlin
CAS:Siremadlin (NVP-HDM 201) is a potent, orally bioavailable and highly specific p53-MDM2 interaction inhibitor.Fórmula:C26H24Cl2N6O4Pureza:98.98% - 99.76%Cor e Forma:SolidPeso molecular:555.41Ref: TM-T5555
1mg55,00€2mg75,00€5mg105,00€1mL*10mM (DMSO)129,00€10mg177,00€25mg319,00€50mg512,00€100mg762,00€Meloxicam sodium
CAS:Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC 50 s of 0.49 μM and 36.6 μM for COX-2 and COX-1, respectively [1].Fórmula:C14H12N3NaO4S2Cor e Forma:SolidPeso molecular:373.383'-Hydroxypterostilbene
CAS:3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.Fórmula:C16H16O4Pureza:98.25% - 99.19%Cor e Forma:SolidPeso molecular:272.3Benzoylpaeoniflorin
CAS:1. Benzoylpaeoniflorin is active against cyclooxygenase-1 and cyclooxygenase-2 enzymes.Fórmula:C30H32O12Pureza:95.86% - 97.28%Cor e Forma:SolidPeso molecular:584.57Purvalanol A
CAS:Purvalanol A (NG-60) is an effective and cell-permeable CDK inhibitor with IC50 of 70/4/35/850 nM for cdk2-cyclin A/B/E, and cdk4-cyclin D1, respectively.Fórmula:C19H25ClN6OPureza:98.13% - 99.68%Cor e Forma:PowderPeso molecular:388.89Cinchonine monohydrochloride hydrate
CAS:Cinchonine monohydrochloride hydrate: natural antimalarial, inhibits platelet aggregation & cancer cell growth, blocks fat cell formation.Fórmula:C19H25ClN2O2Cor e Forma:SolidPeso molecular:348.87Ulinastatin
CAS:Ulinastatin is a multivalent Kunitz-type serine protease inhibitor with anti-inflammatory properties.Fórmula:C13H16O3Pureza:98%Cor e Forma:SolidPeso molecular:220.10994Droxinostat
CAS:Droxinostat (NS 41080) is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 μM and 1.46 μM, greater than 8-fold selective against HDAC3Fórmula:C11H14ClNO3Pureza:99.83%Cor e Forma:SolidPeso molecular:243.69RG7112
CAS:RG7112 (RO5045337) (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor.Fórmula:C38H48Cl2N4O4SPureza:99.66% - 99.9%Cor e Forma:SolidPeso molecular:727.788-Bromo-cAMP sodium salt
CAS:8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. 8-Bromo-cAMP is an activator of cyclic AMP-dependent protein kinase.Fórmula:C10H10BrN5NaO6PPureza:98% - 99.94%Cor e Forma:Off-White PowderPeso molecular:430.08C5 Lenalidomide
CAS:C5 Lenalidomide is an chemical weith inconclusive biological activity.Fórmula:C13H13N3O3Pureza:99.4%Cor e Forma:SolidPeso molecular:259.26Kinetin riboside
CAS:Kinetin riboside (N6-Furfuryladenosine) can induce apoptosis in cancer cells. It inhibits the proliferation of HCT-15 cells(IC50 of 2.5 μM)Fórmula:C15H17N5O5Pureza:98.17%Cor e Forma:White SolidPeso molecular:347.33Dacomitinib
CAS:Dacomitinib (PF299) is an oral selective inhibitor of EGFR, ERBB2, ERBB4 with IC50s: 6, 45.7, 73.7 nM.Fórmula:C24H25ClFN5O2Pureza:99.4% - 99.72%Cor e Forma:SolidPeso molecular:469.94Ref: TM-T2483
1mg35,00€2mg50,00€5mg74,00€1mL*10mM (DMSO)74,00€10mg120,00€25mg170,00€50mg215,00€100mg334,00€200mg421,00€500mg692,00€Flupentixol dihydrochloride
CAS:Flupentixol dihydrochloride is used in therapy of schizophrenia as well as in anxiolytic and depressive disorders.Fórmula:C23H27Cl2F3N2OSPureza:98.76% - >99.99%Cor e Forma:White Or Off-White SolidPeso molecular:507.43Shield-1
CAS:Shield-1 is a specific, high-affinity, and cell-permeable ligand for FK506-binding protein 12 (FKBP).Cost-effective and quality-assured.Fórmula:C42H56N2O10Pureza:99.08%Cor e Forma:SolidPeso molecular:748.9Ref: TM-T13884
1mg152,00€5mg334,00€1mL*10mM (DMSO)500,00€10mg532,00€25mg847,00€50mg1.153,00€100mg1.549,00€500mg3.087,00€Meisoindigo
CAS:Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).Fórmula:C17H12N2O2Pureza:98.03% - 98.19%Cor e Forma:SolidPeso molecular:276.29Tazemetostat
CAS:Tazemetostat (EPZ6438): Oral EZH2 inhibitor, blocks histone H3K27 methylation, potential cancer therapy.Fórmula:C34H44N4O4Pureza:98.24% - ≥95%Cor e Forma:SolidPeso molecular:572.74Ref: TM-T1788
2mg34,00€5mg50,00€1mL*10mM (DMSO)63,00€10mg70,00€25mg87,00€50mg96,00€100mg144,00€500mg363,00€Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Fórmula:C14H12O2Pureza:99.89% - 99.91%Cor e Forma:SolidPeso molecular:212.24Nerol
CAS:Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmiasFórmula:C10H18OPureza:98.59%Cor e Forma:Colorless Oily Liquid LiquidPeso molecular:154.25Ricolinostat
CAS:Ricolinostat (Rocilinostat) is an orally bioavailable, specific inhibitor of histone deacetylase 6 (HDAC6) with potential antineoplastic activity.Fórmula:C24H27N5O3Pureza:97.17% - 99.76%Cor e Forma:SolidPeso molecular:433.5Rilmenidine hemifumarate
CAS:Rilmenidine hemifumarate (S-3341 hemifumarate) is an I1 imidazoline receptor and α2-adrenergic receptor agonist that induces autophagy.Fórmula:C10H16N2OC4H4O4Pureza:98.14%Cor e Forma:SolidPeso molecular:238.28Thalidomide 4'-ether-alkylC2-amine hydrochloride
CAS:Thalidomide 4'-ether-alkylC2-amine hydrochloride (halidomide-linker 6) is a synthesized E3 ligase ligand-linker conjugate.Fórmula:C15H16ClN3O5Pureza:98.56%Cor e Forma:SolidPeso molecular:353.76Sodium Demethylcantharidate
CAS:Sodium Demethylcantharidate (Sodium norcantharidin) is extracted from Mylabris phqlarata pallas and has potent antitumor activity.Fórmula:C8H9O5·NaPureza:99.66% - ≥98%Cor e Forma:SolidPeso molecular:208.14BAY 61-3606 HCl
CAS:BAY 61-3606 HCl: a reversible Syk inhibitor, halts mast cell degranulation, cytokines, and sensitizes MCF-7 cells to TRAIL-induced apoptosis.Fórmula:C20H19ClN6O3Cor e Forma:SolidPeso molecular:426.86FB23-2
CAS:FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).Fórmula:C18H15Cl2N3O3Pureza:97.29% - ≥95%Cor e Forma:SolidPeso molecular:392.24Thalidomide-O-amido-C6-NH2 TFA
CAS:Thalidomide-O-amido-C6-NH2 TFA (Cereblon Ligand-Linker Conjugates 11 TFA), a synthesized E3 ligase ligand-linker conjugate containing a Thalidomide-basedFórmula:C46H53F6N8O16Pureza:95.16%Cor e Forma:SolidPeso molecular:1087.95ICCB280
CAS:ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcomeFórmula:C23H18N2O4Pureza:98.04%Cor e Forma:SolidPeso molecular:386.4Ref: TM-T8839
1mg49,00€5mg100,00€1mL*10mM (DMSO)110,00€10mg173,00€25mg281,00€50mg409,00€100mg572,00€200mg773,00€M50054
CAS:Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.Fórmula:C13H16O4Pureza:97.8%Cor e Forma:SolidPeso molecular:236.26Phenoxyethanol
CAS:Phenoxyethanol (NSC-1864) is germicidal. It often used together with quaternary ammonium compounds.Fórmula:C8H10O2Pureza:99.47%Cor e Forma:Clear To Practically Clear Colourless LiquidPeso molecular:138.16NSC-87877 disodium
CAS:NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.Fórmula:C19H13N3O7S2·2NaPureza:97.89%Cor e Forma:SolidPeso molecular:503.42Lenaldekar
CAS:Lenaldekar (LDK) inhibits T-cell expansion and autoimmune encephalomyelitis.Fórmula:C18H14N4Pureza:97.73%Cor e Forma:SolidPeso molecular:286.33Ref: TM-T24398
1mg64,00€1mL*10mM (DMSO)123,00€5mg129,00€10mg188,00€25mg299,00€50mg427,00€100mg575,00€200mg767,00€Hederacolchiside A1
CAS:Hederacolchiside A1 exhibits anti-leishmanial and anticancer activities by disrupting cell membranes and inducing apoptosis via the PI3K/Akt/mTOR pathway.Fórmula:C47H76O16Pureza:98.76% - 99.92%Cor e Forma:SolidPeso molecular:897.1Ref: TM-T2P2806
1mg46,00€5mg114,00€1mL*10mM (DMSO)161,00€10mg167,00€25mg268,00€50mg408,00€100mg587,00€200mg825,00€Bicyclol
CAS:Bicyclol is an oral anti-hepatitis drug, decreasing ALT/AST levels by 50% and inhibiting HBV/HCV, boosting efficacy with interferon/lamivudine/adefovir.
Fórmula:C19H18O9Pureza:99.64% - 99.85%Cor e Forma:SolidPeso molecular:390.34Calcium dobesilate
CAS:Calcium dobesilate(CaD) has angioprotective properties and protects endothelial cells partly by ameliorating HG induced inflammation.Fórmula:C6H5O5SCa0Pureza:98.39%Cor e Forma:White Or Almost PowderPeso molecular:229.2ZYN57939
CAS:ZYN57939 (MTR-106), an RNA polymerase I inhibitor, treats related diseases with a 0.855 μM IC50 against HT-29 cells.Fórmula:C28H27N7O2SPureza:99.81%Cor e Forma:SolidPeso molecular:525.62CBL0137 hydrochloride
CAS:CBL0137 hydrochloride (Curaxin-137 hydrochloride) is an inhibitor of the histone chaperone FACT, which also activates p53 and inhibits NF-κB.Cost-effective and quality-assured.Fórmula:C21H25ClN2O2Pureza:99.35% - 99.86%Cor e Forma:SolidPeso molecular:372.88TD52
CAS:TD52, an Erlotinib derivative, is an oral CIP2A cancer inhibitor that disrupts Elk1's attachment to the CIP2A promoter.Fórmula:C24H16N4Pureza:99.5%Cor e Forma:SolidPeso molecular:360.41UTL-5g
CAS:UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.Fórmula:C11H8Cl2N2O2Pureza:99.83%Cor e Forma:SolidPeso molecular:271.1Ref: TM-T8845
2mgA consultar5mg66,00€1mL*10mM (DMSO)73,00€10mg94,00€25mg182,00€50mg258,00€100mg366,00€Trametinib (DMSO solvate)
CAS:Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)Fórmula:C28H29FIN5O5SPureza:99.71% - 99.92%Cor e Forma:SolidPeso molecular:693.53TCS PrP Inhibitor 13
CAS:TCS PrP Inhibitor 13 (5-(4-Nitrophenyl)-2-Phenyl-4H-Pyrazol-3-One) is an antiprion agent inhibiting protease-resistant prion protein (PrP-res) accumulation.Fórmula:C15H11N3O3Pureza:99.7%Cor e Forma:SolidPeso molecular:281.27Ref: TM-T23450
5mg35,00€1mL*10mM (DMSO)38,00€10mg55,00€25mg100,00€50mg156,00€100mg231,00€200mg329,00€Cladribine
CAS:Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases.Fórmula:C10H12ClN5O3Pureza:99.58% - >99.99%Cor e Forma:White Crystalline SolidPeso molecular:285.69Talampanel
CAS:Talampanel (LY-300164), an oral selective AMPA receptor antagonist, exhibits anti-seizure and neuroprotective properties.Fórmula:C19H19N3O3Pureza:98.3%Cor e Forma:SolidPeso molecular:337.37BI-847325
CAS:BI-847325 is a selective dual inhibitor of MEK and aurora kinases (AK) with IC50 values of 4 and 15 nM for human MEK2 and AK-C, respectively.Fórmula:C29H28N4O2Pureza:97.13% - 97.54%Cor e Forma:SolidPeso molecular:464.56Oncrasin-1
CAS:Oncrasin 1 is a potent inhibitor of anticancer that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrationsFórmula:C16H12ClNOPureza:99.75%Cor e Forma:SolidPeso molecular:269.73Bioymifi
CAS:Bioymifi (DR5 Activator), a novel TRAIL activator, binds to DR5's ECD, inducing DR5 aggregation and stimulating cell apoptosis. Cost-effective and quality-assured.Fórmula:C22H12BrN3O4SPureza:98% - 99.79%Cor e Forma:SolidPeso molecular:494.32Ref: TM-T2065
1mg34,00€2mg47,00€5mg66,00€1mL*10mM (DMSO)79,00€10mg102,00€25mg202,00€50mg364,00€100mg532,00€ENMD-1068 hydrochloride
CAS:ENMD-1068 hydrochloride: selective PAR2 antagonist, counters liver fibrosis, hinders endometrial cell growth, and induces apoptosis in studies.Fórmula:C15H30ClN3O2Cor e Forma:SolidPeso molecular:319.87Nobiletin
CAS:Nobiletin: a citrus-derived flavone with anti-inflammatory and anti-cancer properties; water-insoluble, very weak acid.Fórmula:C21H22O8Pureza:98.65% - 99.76%Cor e Forma:SolidPeso molecular:402.39Ref: TM-T2834
5mg54,00€1mL*10mM (DMSO)56,00€10mg84,00€25mg117,00€50mg159,00€100mg251,00€200mg371,00€500mg620,00€Glycochenodeoxycholic acid sodium salt
CAS:GCDCA, a bile acid-glycine salt, is a secondary bile acid from colonic microbes.Fórmula:C26H42NNaO5Pureza:95.48% - 99.82%Cor e Forma:SolidPeso molecular:471.61Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFórmula:C42H56F2N8O6Pureza:97.08% - ≥95%Cor e Forma:SolidPeso molecular:806.94Ref: TM-T6007
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)92,00€10mg109,00€25mg172,00€50mg250,00€100mg447,00€PD173955
CAS:PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFórmula:C21H16Cl2N4OSPureza:98.52% - 98.99%Cor e Forma:SolidPeso molecular:443.35Ref: TM-T3063
2mg35,00€5mg50,00€10mg92,00€1mL*10mM (DMSO)94,00€25mg166,00€50mg248,00€100mg371,00€200mg530,00€
