Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(125 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(125 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(92 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5592 produtos de "Apoptose"
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Fenobam
CAS:<p>Fenobam shows inverse agonist activity which blocks the mGlu5 receptor basal activity(IC50: 84 nM).</p>Fórmula:C11H11ClN4O2Pureza:99.93%Cor e Forma:SolidPeso molecular:266.68PF-4878691
CAS:<p>PF-4878691 (3M-852A) is an effective and selective Toll-like receptor 7 agonists modelled. It is used to dissociate its antiviral and inflammatory activities.</p>Fórmula:C17H23N5O2SPureza:98.43%Cor e Forma:SolidPeso molecular:361.46IMB-XH1
CAS:<p>IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor.</p>Fórmula:C19H15N3OSPureza:98%Cor e Forma:SolidPeso molecular:333.41Butylated hydroxytoluene
CAS:<p>Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.</p>Fórmula:C15H24OPureza:99.72%Cor e Forma:Colourless Solid PowderPeso molecular:220.35Vorinostat
CAS:<p>Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11.</p>Fórmula:C14H20N2O3Pureza:99.47% - 99.65%Cor e Forma:White Crystalline SolidPeso molecular:264.32Lercanidipine
CAS:<p>Lercanidipine (Masnidipine) is a calcium channel blocker of the dihydropyridine class.</p>Fórmula:C36H41N3O6Pureza:99.92%Cor e Forma:White To Light Yellow SolidPeso molecular:611.73MV1
CAS:<p>MV1 is an IAP antagonist. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins.</p>Fórmula:C33H44N4O5Pureza:99.86%Cor e Forma:SolidPeso molecular:576.73Maritoclax
CAS:<p>Maritoclax (Marinopyrrole A) (Marinopyrrole A) is a novel and specific Mcl-1 inhibitor, shows >8 fold selectivity than BCL-xl (IC50 > 80 μM),with an IC50 value</p>Fórmula:C22H12Cl4N2O4Pureza:99.87%Cor e Forma:SolidPeso molecular:510.15Ac-YVAD-CMK
CAS:<p>Ac-YVAD-CMK: Irreversible Caspase-1 inhibitor; halts pyroptosis, IL-1β/IL-18; neuroprotective and anti-inflammatory.</p>Fórmula:C24H33ClN4O8Pureza:97.08% - 99.909%Cor e Forma:SolidPeso molecular:540.99Nitroxoline
CAS:<p>Nitroxoline (5-nitroquinolin-8-ol) is a urinary antibacterial agent active against susceptible gram-positive and gram-negative organisms commonly found in</p>Fórmula:C9H6N2O3Pureza:97.74% - 99.09%Cor e Forma:SolidPeso molecular:190.16Aminoguanidine hydrochloride
CAS:<p>Aminoguanidine hydrochloride (Hydrazinecarboximidamide) is a diamine oxidase and NO synthase inhibitor, used in the treatment of diabetic nephropathy.</p>Fórmula:CH6N4·HClPureza:99.80%Cor e Forma:White To Off-White SolidPeso molecular:110.55Ruplizumab
CAS:<p>PF-03732010 is a humanized antibody targeting P-calmodulin with antitumor and antimetastatic activity.</p>Pureza:98.5% (SDS-PAGE); 98.7% (SEC-HPLC) - 98.5% (SDS-PAGE); 98.7% (SEC-HPLC)Cor e Forma:LiquidOxaprozin
CAS:<p>Oxaprozin (Oxaprozinum) is a Nonsteroidal Anti-inflammatory Drug.</p>Fórmula:C18H15NO3Pureza:98.53%Cor e Forma:SolidPeso molecular:293.32Larotaxel
CAS:<p>Larotaxel (XRP9881), a taxane with anticancer properties, stabilizes microtubules, induces apoptosis, and is researched in breast and bladder cancer.</p>Fórmula:C45H53NO14Pureza:99.22%Cor e Forma:SolidPeso molecular:831.9Mitotane
CAS:<p>Mitotane (NCI-C04933) is a derivative of the insecticide dichlorodiphenyldichloroethane that specifically inhibits cells of the adrenal cortex.</p>Fórmula:C14H10Cl4Pureza:99.89% - ≥95%Cor e Forma:Less Powder (Ntp 1992) Physical Description Colorless Powder (Ntp 1992)Peso molecular:320.04Ligandrol
CAS:<p>Ligandrol is a novel nonsteroidal, oral SARM that binds to the androgen receptor with high affinity (Ki: 1 nM) and selectivity.</p>Fórmula:C14H12F6N2OPureza:99.94% - >99.99%Cor e Forma:SolidPeso molecular:338.25Cl-amidine hydrochloride
CAS:<p>Cl-amidine hydrochloride is an orally available PAD inhibitor that blocks histone 3 deimination.Cost-effective and quality-assured.</p>Fórmula:C14H20Cl2N4O2Pureza:92.34% - 98.14%Cor e Forma:SolidPeso molecular:347.24Tegaserod maleate
CAS:<p>Tegaserod (SDZ-HTF-919), a 5-HT4 agonist for irritable bowel syndrome, was withdrawn by FDA on March 30, 2007, due to heart risk concerns.</p>Fórmula:C20H27N5O5Pureza:98% - 99.06%Cor e Forma:White PowderPeso molecular:417.46Nebivolol hydrochloride
CAS:<p>Nebivolol hydrochloride is a beta-1 blocker and vasodilator treating hypertension and heart failure in the elderly.</p>Fórmula:C22H25F2NO4·HClPureza:99.77% - >99.99%Cor e Forma:White To Off-White PowderPeso molecular:441.90Olanzapine
CAS:<p>Olanzapine (LY170053) is an atypical antipsychotic that is used currently in the treatment of schizophrenia and bipolar illness.</p>Fórmula:C17H20N4SPureza:99.86% - ≥95%Cor e Forma:Yellowish Crystalline PowderPeso molecular:312.43Lornoxicam
CAS:<p>Lornoxicam (Chlortenoxicam) (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory, and</p>Fórmula:C13H10ClN3O4S2Pureza:98.74% - 99.28%Cor e Forma:Crystalline SolidPeso molecular:371.82Benazepril hydrochloride
CAS:<p>Benazepril hydrochloride (CGS 14824A HCl) is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension.</p>Fórmula:C24H29ClN2O5Pureza:99.68% - ≥95%Cor e Forma:Crystalline SolidPeso molecular:460.95Dacarbazine
CAS:<p>Dacarbazine (DTIC-Dome) is an antineoplastic agent. It has significant activity against melanomas.</p>Fórmula:C6H10N6OPureza:99.78% - 99.87%Cor e Forma:Ivory Microcrystaline Substance Physical Description White To Ivory Microcrystals Or Off-White Crystalline Solid (Ntp 1992)Peso molecular:182.18Hydroxyurea
CAS:<p>Hydroxyurea (Hydroxycarbamide), an antineoplastic agent, inhibits DNA synthesis through the inhibition of ribonucleoside diphosphate reductase.</p>Fórmula:CH4N2O2Pureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:76.05AZD7624
CAS:<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Fórmula:C27H30FN5O3Pureza:98.82%Cor e Forma:SolidPeso molecular:491.56S55746
CAS:<p>S55746 (BLC201) is an effective and selective BCL-2 inhibitor (Ki: 1.3 nM and a Kd of 3.9 nM).</p>Fórmula:C43H42N4O6Pureza:97.14%Cor e Forma:SolidPeso molecular:710.82Ramipril
CAS:<p>Ramipril (Altace) is a long-acting angiotensin-converting enzyme inhibitor.</p>Fórmula:C23H32N2O5Pureza:98.11% - 99.93%Cor e Forma:White SolidPeso molecular:416.51GPI-1046
CAS:<p>GPI-1046: immunophilin ligand, no antibiotic effect, reduces ethanol intake by boosting GLT1 in PFC and NAc-core.</p>Fórmula:C20H28N2O4Pureza:99.69%Cor e Forma:SolidPeso molecular:360.45Durvalumab
CAS:<p>Durvalumab is a humanized antibody for cancer, inhibiting PD-L1/PD-1 and CD80 interactions at very low concentrations.</p>Pureza:SDS-PAGE:97.2%;SEC-HPLC:95.3%Cor e Forma:LiquidPeso molecular:146.03 kDaSemapimod tetrahydrochloride
CAS:<p>Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) is a mitogen-activated protein kinase blocker and pro-inflammatory cytokine production inhibitor.</p>Fórmula:C34H56Cl4N18O2Pureza:97.21% - 99.8%Cor e Forma:SolidPeso molecular:890.74iFSP1
CAS:<p>iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverse</p>Fórmula:C20H13N5Pureza:98.74% - 99.74%Cor e Forma:SolidPeso molecular:323.35Terfenadine
CAS:<p>Terfenadine, metabolized to fexofenadine by CYP3A4, is a non-sedative antihistamine targeting H1 receptors.</p>Fórmula:C32H41NO2Pureza:98.76% - 99.75%Cor e Forma:SolidPeso molecular:471.67Mycophenolic acid
CAS:<p>Mycophenolic acid (Mycophenolate) is an inosine monophosphate dehydrogenase(IMPDH) inhibitor with anti-proliferative activity.</p>Fórmula:C17H20O6Pureza:98.79% - 99.77%Cor e Forma:SolidPeso molecular:320.34Dabuzalgron
CAS:<p>Dabuzalgron (Ro 115-1240) is an orally active selective alpha-1A adrenergic receptor agonist used to treat urinary incontinence.</p>Fórmula:C12H16ClN3O3SPureza:98.35%Cor e Forma:SolidPeso molecular:317.79Gboxin
CAS:<p>Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.</p>Fórmula:C22H33ClN2O2Pureza:99.96% - >99.99%Cor e Forma:SolidPeso molecular:392.96Ascorbyl palmitate
CAS:<p>Ascorbyl palmitate (L-Ascorbic acid 6-hexadecanoate), an ester formed from ascorbic acid and palmitic acid, produces a fat-soluble form of vitamin C.</p>Fórmula:C22H38O7Pureza:99.52%Cor e Forma:White Or Yellowish White Powder White Or Yellowish-White Powder With A Citrus-Like OdourPeso molecular:414.53WJ-39
CAS:<p>WJ-39 is an AR inhibitor that may be used to ameliorate renal insufficiency and fibrosis.</p>Fórmula:C19H14Cl2KNO4Pureza:99.45%Cor e Forma:SoildPeso molecular:430.32Lilotomab
CAS:<p>Lilotomab (HH1), a murine anti-CD37 monoclonal antibody, demonstrates anti-tumor activity by reducing clonogenic survival [1].</p>Pureza:97.4% (SDS-PAGE); 99.1% (SEC-HPLC) - 97.4% (SDS-PAGE); 99.1% (SEC-HPLC)Cor e Forma:LiquidSodium butanoate
CAS:<p>Sodium butanoate (Sodium Butyrate) is the sodium salt of butyrate with potential antineoplastic activity.</p>Fórmula:C4H7NaO2Pureza:98.02% - 99.79%Cor e Forma:White PowderPeso molecular:110.09Cemiplimab
CAS:<p>Cemiplimab, a human antibody, blocks PD-1 to inhibit T-cell suppression in metastatic and skin cancer studies.</p>Pureza:SDS-PAGE:97.2%;SEC-HPLC:95.2%Cor e Forma:LiquidPeso molecular:143.81 kDaPenfluridol
CAS:<p>Penfluridol (TLP-607) is a highly potent antipsychotic.</p>Fórmula:C28H27ClF5NOPureza:98.9% - 99.87%Cor e Forma:Off-White To White Crystalline PowderPeso molecular:523.97Budigalimab
CAS:<p>Budigalimab (ABBV 181) is a humanized monoclonal antibody targeting PD-1 with potential antitumor activity.</p>Pureza:97% (SDS-PAGE); 98.8% (SEC-HPLC) - 97% (SDS-PAGE); 98.8% (SEC-HPLC)Cor e Forma:LiquidEmeramide
CAS:<p>Emeramide (BDTH2) is a thiol-redox antioxidant. It is also a heavy metal chelator.</p>Fórmula:C12H16N2O2S2Pureza:98.73%Cor e Forma:SolidPeso molecular:284.4Ibuprofen
CAS:<p>Ibuprofen, an NSAID, reduces pain, inflammation, and fever by limiting prostaglandin production.</p>Fórmula:C13H18O2Pureza:99.7% - 99.81%Cor e Forma:Colorless Solid CrystallinePeso molecular:206.28Hexylresorcinol
CAS:<p>Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.</p>Fórmula:C12H18O2Pureza:99.26% - 99.51%Cor e Forma:Solid Solid Particulate/PowderPeso molecular:194.27MD-224
CAS:<p>MD-224 is a highly potent and efficacious MDM2 degrader based on the proteolysistargeting chimera (PROTAC) concept,and as a new class of anticancer agent.</p>Fórmula:C48H43Cl2FN6O6Pureza:99.07% - >99.99%Cor e Forma:SolidPeso molecular:889.8Sophocarpine monohydrate
CAS:<p>Sophocarpine monohydrate, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.</p>Fórmula:C15H22N2OPureza:99.55%Cor e Forma:SolidPeso molecular:246.35Metamizole sodium hydrate
CAS:<p>Metamizole sodium hydrate (Analgin) is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX).</p>Fórmula:C13H18N3NaO5SPureza:99.69% - 99.89%Cor e Forma:White Or Light Yellow Crystalline Powder Odorless Tiny BitterPeso molecular:351.36Proparacaine hydrochloride
CAS:<p>Proparacaine Hydrochloride is the hydrochloride salt form of proparacaine, a benzoic acid derivative with local anesthetic property.</p>Fórmula:C16H26N2O3·HClPureza:99.47% - 99.87%Cor e Forma:SolidPeso molecular:330.86Sodium metatungstate
CAS:<p>Sodium metatungstate (Sodium polyoxotungstate) is a potent inhibitor of ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)(Ki values of 2.58 μM, 3.26 μM</p>Fórmula:H2Na6O40W12Pureza:80%Cor e Forma:White - GreyPeso molecular:2985.99
