Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(142 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(138 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(14 produtos)
- Survivina(14 produtos)
- TNF(89 produtos)
- c-RET(56 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5903 produtos de "Apoptose"
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Sugemalimab
CAS:<p>Sugemalimab: human anti-PD-L1 IgG4 mAb with anticancer properties for non-small cell lung cancer.</p>Cor e Forma:LiquidInezetamab
CAS:Inezetamab is a bispecific monoclonal antibody functioning as an MSLN inhibitor and CD40 agonist, suitable for investigating solid tumours.Pureza:95% - 99.1% (SDS-PAGE); 99.7% (SEC-HPLC)Cor e Forma:LiquidLinvoseltamab
CAS:Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/Cor e Forma:LiquidVonsetamig
CAS:Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.Cor e Forma:LiquidTagitanlimab
CAS:<p>Tagitanlimab (HBM-9167) is a humanized IgG1κ anti-PD-L1 antibody, potentially for recurrent/metastatic NPC.</p>Cor e Forma:LiquidRMC5127
CAS:RMC5127 is an orally available RAS G12V inhibitor, CNS and brain permeability, induces apoptosis in KRAS G12V mutant cancer cells, antitumour.Fórmula:C57H75N9O9SPureza:97.54%Cor e Forma:SolidPeso molecular:1062.32Quilizumab
CAS:Quilizumab (Anti-Human NGcGM3 Recombinant Antibody) is a humanised monoclonal antibody ,the M1-prime fragment of membrane-bound IgE, depleting memory B cellsPureza:95%Cor e Forma:LiquidDalotuzumab
CAS:Dalotuzumab (MK-0646) is an anti-IGF-1R mAb that inhibits oncogenic signaling, inducing tumor cell apoptosis.Pureza:95%Cor e Forma:LiquidPeso molecular:146.4 (kDa)Afelimomab
CAS:<p>Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].</p>Cor e Forma:LiquidTabalumab
CAS:Tabalumab (LY2127399) is a humanised monoclonal antibody targeting BAFF that neutralises both soluble and membrane-bound forms of BLyS , autoimmune diseases.Pureza:95%Cor e Forma:LiquidAzintuxizumab
CAS:<p>Azintuxizumab, an IgG4 bispecific antibody, targets BCMA, offering dual-action immunotherapy for relapsed/refractory multiple myeloma in preclinical studies.</p>Pureza:95% - 95%Cor e Forma:LiquidPucotenlimab
CAS:Pucotenlimab (HX008) is an anti-PD-1 mAb that blocks PD-1/PD-L1/2 interactions, restoring immune function against solid tumours.Pureza:95%Cor e Forma:LiquidNeihulizumab
CAS:Neihulizumab is an anti-CD162 antibody that induces apoptosis in activated T cells for treating GVHD and psoriasis.Pureza:95%Cor e Forma:LiquidCosibelimab
CAS:<p>Cosibelimab, a fully human monoclonal antibody, blocks PD-L1, enabling ADCC and CDC against cancer cells.</p>Cor e Forma:LiquidGeptanolimab
CAS:Geptanolimab (CBT-501) is a humanized IgG4κ antibody against PD-1, blocking PD-L1/PD-L2 binding to reactivate T cell activity.Pureza:95% - 99.5% (SDS-PAGE); 97.6% (SEC-HPLC)Cor e Forma:LiquidAcasunlimab
CAS:Acasunlimab (GEN1046) is a bsAb that targets PD-L1 and 4-1BB, boosting T/NK cells and blocking PD-1/PD-L1 in cancer research.Cor e Forma:LiquidTuvonralimab
CAS:<p>Tuvonralimab, a combo of anti-PD-1/IgG4 and anti-CTLA-4/IgG1 antibodies, blocks dual immune checkpoints.</p>Cor e Forma:LiquidLicaminlimab
<p>Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.</p>Cor e Forma:Odour LiquidRemtolumab
CAS:Remtolumab (ABT-122) is a dual inhibitor of TNFα and IL-17A for rheumatoid arthritis research.Cor e Forma:LiquidToripalimab
CAS:Toripalimab is a humanized anti-PD-1 monoclonal antibody used as an immune checkpoint inhibitor in research for advanced malignancies like nasopharyngeal carcinoma.Pureza:95% - 95.2% (SDS-PAGE); 96.8% (SEC-HPLC)Cor e Forma:LiquidAnti-Mouse TNFR2 Antibody (TR75-54.7)
Anti-Mouse TNFR2 Antibody is an Armenian Hamster-derived IgG inhibitor specifically targeting mouse TNFR2.Cor e Forma:Odour LiquidVudalimab
CAS:Vudalimab: humanized antibody, blocks PD-1 & CTLA-4, boosts selective T-cell tumor response.Cor e Forma:LiquidTecaginlimab
CAS:Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, targets CD40/4-1BB to boost tumor immunity.Cor e Forma:LiquidIvuxolimab
CAS:<p>Ivuxolimab is a human IgG2 antibody that acts as an OX40 agonist, promoting T cell responses for anti-tumor immunity research.</p>Pureza:95% - 95%Cor e Forma:LiquidPQA-18
CAS:PQA-18, an inhibitor of p21-activated kinase 2 (PAK2; IC50 = 10 nM), is derived from Ppc-1 (product number 42352) and exhibits immunosuppressive properties. It inhibits IL-2 production in Jurkat T cells induced by Concanavalin A (product number 14951) with an IC50 of 400 nM. Topically applied at 0.1%, PQA-18 reduces the severity of atopic dermatitis, serum IgE levels, and skin thickness in the NC/Nga mouse model. A lower concentration of 0.05% also decreases skin nerve fiber density in NC/Nga mice. Additionally, PQA-18 administered at 4 mg/kg improves graft survival in a rat small intestine transplantation model.Fórmula:C25H31NO4Cor e Forma:SolidPeso molecular:409.52Anti-Mouse PD-1 Antibody (S-5001)
Anti-MousePD-1Antibody (S-5001) is an IgG1 antibody inhibitor that targets mouse PD-1.Cor e Forma:Odour LiquidCadonilimab
CAS:<p>Cadonilimab (AK104) is a tetravalent PD-1/CTLA-4 bispecific humanised antibody that activates T cells by enhancing IL-2 and IFN-γ secretion.</p>Pureza:95% - 95%Cor e Forma:LiquidLesabelimab
CAS:Lesabelimab (LDP) is an anti-CD274 monoclonal antibody of the immunoglobulin G1-kappa subclass.Cor e Forma:LiquidGilvetmab
CAS:Gilvetmab is a caninized anti-PD-1 antibody approved for veterinary use, researched for stage I-III mast cell tumors and stage II-III melanoma in dogs.Pureza:95% - 97.9% (SDS-PAGE); 97.4% (SEC-HPLC)Cor e Forma:LiquidMDM2-p53-IN-18
CAS:MDM2-p53-IN-18, also known as Compd A-7b, is an inhibitor of the MDM2-p53 interaction [1].Fórmula:C19H16Cl2FN3O4Peso molecular:440.25Tegoprubart
CAS:Tegoprubart (anti-CD40L mAb) inhibits the CD40-CD40L pathway, reducing immune responses and promoting tolerance in transplant models.Pureza:95%Cor e Forma:LiquidPifithrin-β
CAS:potent p53 inhibitorFórmula:C16H16N2SPureza:98%Cor e Forma:SolidPeso molecular:268.38Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody
Anti-Mouse/Human phosphorylated PD-1/CD279 Antibody (407.6G12) is an IgG2a, κ antibody inhibitor derived from mice, targeting phosphorylated PD-1/CD279 in both mice and humans.Cor e Forma:Odour LiquidFosinopril
CAS:Fosinopril, a prodrug ACE inhibitor for hypertension, converts to active fosinoprilat.Fórmula:C30H46NO7PPureza:98%Cor e Forma:SolidPeso molecular:563.6625Cifurtilimab
CAS:<p>Cifurtilimab (SEA-CD40) is a humanised monoclonal antibody acting as a CD40 agonist. It enhances binding to activated FcγRIIIa, anticancer.</p>Pureza:95%Cor e Forma:LiquidAmantadine sulfate
CAS:Amantadine: antiviral, anti-Parkinson's, blocks NMDA receptors, boosts dopamine/norepinephrine release.Fórmula:C20H36N2O4SCor e Forma:White Fine Crystalline PowderPeso molecular:400.58Reozalimab
CAS:<p>Reozalimab (LY3434172) is a bispecific monoclonal antibody targeting PD-1/PD-L1, antitumour and enhances T-cell activation in vitro.</p>Pureza:95% - 95%Cor e Forma:LiquidCephalotaxine
CAS:Fórmula:C18H21NO4Pureza:>98.0%(GC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:315.37L-Selenocystine
CAS:Fórmula:C6H12N2O4Se2Pureza:>97.0%(T)Cor e Forma:Light yellow to Brown powder to crystalPeso molecular:334.09Dasatinib-d8
CAS:Dasatinib D8 is deuterium-labeled dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.Fórmula:C22H26ClN7O2SPureza:98%Cor e Forma:SolidPeso molecular:496.06Propylparaben-d4
CAS:<p>Propylparaben-d4 is a deuterated compound of Propylparaben. Propylparaben has a CAS number of 94-13-3. Propylparaben is an antimicrobial agent, preservative, flavouring agent</p>Fórmula:C10H8D4O3Cor e Forma:SolidPeso molecular:184.23Pioglitazone-d4
CAS:Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .Fórmula:C19H20N2O3SPureza:98%Cor e Forma:SolidPeso molecular:360.46D-F07
CAS:D-F07 is a novel fluorescent IRE-1 RNase inhibitor and a tricyclic chromone with potential anticancer activity.Fórmula:C18H21NO6Pureza:98.31% - 99.31%Cor e Forma:SoildPeso molecular:347.36Meloxicam-d3
CAS:<p>Meloxicam D4: deuterium-labeled, non-steroidal anti-inflammatory; COX-1 inhibitor (IC50: 36.6μM), COX-2 inhibitor (IC50: 0.49μM).</p>Fórmula:C14H13N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:354.425'-Deoxy-5'-methylthioadenosine-d3
CAS:<p>5'-Deoxy-5'-methylthioadenosine-d3 is a deuterated MTA analog used as an internal standard in metabolomic studies.</p>Fórmula:C11H15N5O3SCor e Forma:SolidPeso molecular:300.35Stavudine-α,α,α,6-d4
CAS:<p>Stavudine-α,α,α,6-d4 is a deuterated compound of Stavudine. Stavudine has a CAS number of 3056-17-5. Stavudine, a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.</p>Fórmula:C10H8D4N2O4Cor e Forma:SolidPeso molecular:228.24Galanthamine-O-methyl-d3
CAS:Galanthamine-O-methyl-d3 is a deuterated compound of Galanthamine-O-methyl. Galanthamine-O-methyl has a CAS number of 357-70-0. Galanthamine is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.Fórmula:C17H18D3NO3Cor e Forma:SolidPeso molecular:290.37Limonin glucoside
CAS:Limonin glucoside: a citrus compound, blocks HIV/HTLV-1, triggers cancer cell death, kills Aedes larvae.Fórmula:C32H42O14Cor e Forma:SolidPeso molecular:650.674GZD856 formic
CAS:GZD856 formic inhibits PDGFRα/β (IC50: 68.6, 136.6 nM) & Bcr-Abl (IC50: 19.9, 15.4 nM), with antitumor properties.Fórmula:C30H29F3N6O3Cor e Forma:SolidPeso molecular:578.58Desethylamiodarone
CAS:Diethylamiodarone is the main metabolite of amiodarone in vivo.Fórmula:C23H25I2NO3Pureza:98%Cor e Forma:SolidPeso molecular:617.26
