Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(143 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(139 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(18 produtos)
- Survivina(14 produtos)
- TNF(89 produtos)
- c-RET(58 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5966 produtos de "Apoptose"
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Visilizumab
CAS:Visilizumab is a humanized anti-CD3 IgG2 mAb with low Fc binding, modulating T-cell function for ulcerative colitis and Crohn's.Pureza:95%Cor e Forma:LiquidAfelimomab
CAS:<p>Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].</p>Cor e Forma:LiquidAnti-Mouse TNFR2 Antibody (TR75-54.7)
Anti-Mouse TNFR2 Antibody is an Armenian Hamster-derived IgG inhibitor specifically targeting mouse TNFR2.Cor e Forma:Odour LiquidMicrotubule inhibitor 8
CAS:<p>Microtubule Inhibitor 8 (MP-HJ-1b) serves as a potent disruptor of microtubule function, inducing cell death via ferroptosis and demonstrating anti-tumor effects [1] [2].</p>Fórmula:C21H15N3O2SCor e Forma:SolidPeso molecular:373.43Linvoseltamab
CAS:Linvoseltamab, a bispecific antibody, targets both BCMA (TNFRSF17) and CD3 epsilon, demonstrating a favorable safety profile and promising efficacy in relapsed/Cor e Forma:LiquidVonsetamig
CAS:Vonsetamig, a humanized immunoglobulin G4-kappa monoclonal antibody, targets both TNFRSF17 and CD3E. It serves as an antineoplastic agent.Cor e Forma:LiquidAnti-Mouse VEGFR-2 Antibody (DC101)
Anti-Mouse VEGFR-2 Antibody (DC101) is a rat-derived monoclonal antibody against mouse VEGFR2/KDR/Flk-1, serving as a mouse analogue of ramucirumab.Pureza:99%Cor e Forma:Odour LiquidQuilizumab
CAS:Quilizumab (Anti-Human NGcGM3 Recombinant Antibody) is a humanised monoclonal antibody ,the M1-prime fragment of membrane-bound IgE, depleting memory B cellsPureza:95%Cor e Forma:LiquidAnti-Mouse PD-1 Antibody (S-5001)
Anti-MousePD-1Antibody (S-5001) is an IgG1 antibody inhibitor that targets mouse PD-1.Cor e Forma:Odour LiquidTagitanlimab
CAS:<p>Tagitanlimab (HBM-9167) is a humanized IgG1κ anti-PD-L1 antibody, potentially for recurrent/metastatic NPC.</p>Cor e Forma:LiquidPifithrin-β
CAS:potent p53 inhibitorFórmula:C16H16N2SPureza:98%Cor e Forma:SolidPeso molecular:268.38Cosibelimab
CAS:<p>Cosibelimab, a fully human monoclonal antibody, blocks PD-L1, enabling ADCC and CDC against cancer cells.</p>Cor e Forma:LiquidAHR agonist 3
CAS:<p>AHR agonist 3 is an agent with therapeutic activity.</p>Fórmula:C18H10N2OPureza:98%Cor e Forma:SolidPeso molecular:270.28Bleselumab
CAS:Bleselumab (ASKP 1240) is a humanised monoclonal antibody targeting CD40, inhibiting immune responses, organ transplant rejection.Pureza:95%Cor e Forma:LiquidTabalumab
CAS:Tabalumab (LY2127399) is a humanised monoclonal antibody targeting BAFF that neutralises both soluble and membrane-bound forms of BLyS , autoimmune diseases.Pureza:95%Cor e Forma:LiquidSugemalimab
CAS:<p>Sugemalimab: human anti-PD-L1 IgG4 mAb with anticancer properties for non-small cell lung cancer.</p>Cor e Forma:LiquidNeihulizumab
CAS:Neihulizumab is an anti-CD162 antibody that induces apoptosis in activated T cells for treating GVHD and psoriasis.Pureza:95%Cor e Forma:LiquidLesabelimab
CAS:Lesabelimab (LDP) is an anti-CD274 monoclonal antibody of the immunoglobulin G1-kappa subclass.Cor e Forma:LiquidReozalimab
CAS:Reozalimab (LY3434172) is a bispecific monoclonal antibody targeting PD-1/PD-L1, antitumour and enhances T-cell activation in vitro.Pureza:95% - 98.1% (SDS-PAGE); 96.2% (SEC-HPLC)Cor e Forma:LiquidRemtolumab
CAS:Remtolumab (ABT-122) is a dual inhibitor of TNFα and IL-17A for rheumatoid arthritis research.Cor e Forma:LiquidFrexalimab
CAS:Frexalimab (SAR441344; INX-021), a monoclonal antibody that targets the CD40 ligand (CD40L), shows promise for research in multiple sclerosis [1].Pureza:95% - 95%Cor e Forma:LiquidRavagalimab
CAS:Ravagalimab (ABBV-323) is a CD40 antagonist monoclonal antibody, investigated for Crohn’s disease and Sjögren’s syndrome to evaluate immune modulation.Pureza:95% - 96.9% (SDS-PAGE); 99.5% (SEC-HPLC)Cor e Forma:LiquidAcasunlimab
CAS:Acasunlimab (GEN1046) is a bsAb that targets PD-L1 and 4-1BB, boosting T/NK cells and blocking PD-1/PD-L1 in cancer research.Cor e Forma:LiquidFrataxin-IN-1
CAS:Frataxin-IN-1 inhibits the mitochondrial protein Frataxin with IC50 45 μM and is used in Friedreich’s ataxia research linked to mitochondrial defects.Fórmula:C20H23NO6Pureza:99.34%Peso molecular:373.4Vudalimab
CAS:Vudalimab: humanized antibody, blocks PD-1 & CTLA-4, boosts selective T-cell tumor response.Cor e Forma:LiquidToralizumab
CAS:<p>Toralizumab: humanized mAb targeting CD40L to curb T cell signaling and explore SLE treatment.</p>Cor e Forma:LiquidPeso molecular:148.43 (kD)Iratumumab
CAS:Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.Cor e Forma:LiquidTuvonralimab
CAS:<p>Tuvonralimab, a combo of anti-PD-1/IgG4 and anti-CTLA-4/IgG1 antibodies, blocks dual immune checkpoints.</p>Cor e Forma:LiquidPQA-18
CAS:PQA-18, an inhibitor of p21-activated kinase 2 (PAK2; IC50 = 10 nM), is derived from Ppc-1 (product number 42352) and exhibits immunosuppressive properties. It inhibits IL-2 production in Jurkat T cells induced by Concanavalin A (product number 14951) with an IC50 of 400 nM. Topically applied at 0.1%, PQA-18 reduces the severity of atopic dermatitis, serum IgE levels, and skin thickness in the NC/Nga mouse model. A lower concentration of 0.05% also decreases skin nerve fiber density in NC/Nga mice. Additionally, PQA-18 administered at 4 mg/kg improves graft survival in a rat small intestine transplantation model.Fórmula:C25H31NO4Cor e Forma:SolidPeso molecular:409.52Geptanolimab
CAS:Geptanolimab (CBT-501) is a humanized IgG4κ antibody against PD-1, blocking PD-L1/PD-L2 binding to reactivate T cell activity.Pureza:95% - 99.5% (SDS-PAGE); 97.6% (SEC-HPLC)Cor e Forma:LiquidLicaminlimab
<p>Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.</p>Cor e Forma:Odour LiquidAfimkibart
CAS:Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.Pureza:95% - 99.2% (SDS-PAGE); 95.3% (SEC-HPLC)Cor e Forma:SoildL-Selenocystine
CAS:Fórmula:C6H12N2O4Se2Pureza:>97.0%(T)Cor e Forma:Light yellow to Brown powder to crystalPeso molecular:334.09Cephalotaxine
CAS:Fórmula:C18H21NO4Pureza:>98.0%(GC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:315.37Pioglitazone-d4
CAS:Pioglitazone D4 is a deuterium labeled Pioglitazone. Pioglitazone is a agonist of PPARγ .Fórmula:C19H20N2O3SPureza:98%Cor e Forma:SolidPeso molecular:360.46Propylparaben-d4
CAS:<p>Propylparaben-d4 is a deuterated compound of Propylparaben. Propylparaben has a CAS number of 94-13-3. Propylparaben is an antimicrobial agent, preservative, flavouring agent</p>Fórmula:C10H8D4O3Cor e Forma:SolidPeso molecular:184.23Meloxicam-d3
CAS:<p>Meloxicam D4: deuterium-labeled, non-steroidal anti-inflammatory; COX-1 inhibitor (IC50: 36.6μM), COX-2 inhibitor (IC50: 0.49μM).</p>Fórmula:C14H13N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:354.42Dasatinib-d8
CAS:Dasatinib D8 is deuterium-labeled dasatinib. Dasatinib is a dual Bcr-Abl and Src family tyrosine kinase inhibitor.Fórmula:C22H26ClN7O2SPureza:98%Cor e Forma:SolidPeso molecular:496.065'-Deoxy-5'-methylthioadenosine-d3
CAS:<p>5'-Deoxy-5'-methylthioadenosine-d3 is a deuterated MTA analog used as an internal standard in metabolomic studies.</p>Fórmula:C11H15N5O3SCor e Forma:SolidPeso molecular:300.35Limonin glucoside
CAS:Limonin glucoside: a citrus compound, blocks HIV/HTLV-1, triggers cancer cell death, kills Aedes larvae.Fórmula:C32H42O14Cor e Forma:SolidPeso molecular:650.674Stavudine-α,α,α,6-d4
CAS:<p>Stavudine-α,α,α,6-d4 is a deuterated compound of Stavudine. Stavudine has a CAS number of 3056-17-5. Stavudine, a nucleoside reverse transcriptase inhibitor analog of thymidine, has activity against HIV.</p>Fórmula:C10H8D4N2O4Cor e Forma:SolidPeso molecular:228.24D-F07
CAS:D-F07 is a novel fluorescent IRE-1 RNase inhibitor and a tricyclic chromone with potential anticancer activity.Fórmula:C18H21NO6Pureza:98.31% - 99.31%Cor e Forma:SoildPeso molecular:347.36Galanthamine-O-methyl-d3
CAS:Galanthamine-O-methyl-d3 is a deuterated compound of Galanthamine-O-methyl. Galanthamine-O-methyl has a CAS number of 357-70-0. Galanthamine is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.Fórmula:C17H18D3NO3Cor e Forma:SolidPeso molecular:290.37EGFR-IN-117
CAS:EGFR-IN-117 (Compound 8h) exhibits inhibitory activity against EGFR mutations, specifically targeting the tumor environment and inducing apoptosis in cancer cells. This compound effectively inhibits the proliferation of H1975, PC-9, and mutant EGFR cells including BaF3-EGFRL858R/T790M/C797S and BaF3–C797S/Del19/T790M, with IC50 values of 13 nM, 19 nM, 1.2 nM, and 1.3 nM respectively. Additionally, EGFR-IN-117 demonstrates anti-tumor activity in mouse models.Fórmula:C25H30BrN7O2SCor e Forma:SolidPeso molecular:572.52MCL-1/BCL-2-IN-1
CAS:MCL-1/BCL-2-IN-2 (Compound Nap-1) is a potent and selective dual inhibitor of Mcl-1 and Bcl-2 with IC 50 s of 4.45 and 3.18 μM, respectively [1].Fórmula:C31H27BrN2O3SPureza:98%Cor e Forma:SolidPeso molecular:587.53Diquafosol Free Base
CAS:<p>Diquafosol Free Base is a purinoceptor P2Y(2) receptor agonist.</p>Fórmula:C18H26N4O23P4Cor e Forma:SolidPeso molecular:790.31Ionomycin calcium
CAS:<p>Ionomycin calcium (SQ23377 calcium) is an effective and selective calcium ionophore, exhibiting high specificity for calcium ions. Cost-effective and quality-assured.</p>Fórmula:C41H70CaO9Pureza:98% - 98.11%Cor e Forma:SolidPeso molecular:747.07Dalbinol
CAS:<p>Dalbinol is a useful organic compound for research related to life sciences. The catalog number is T124857 and the CAS number is 41993-79-7.</p>Fórmula:C23H22O8Cor e Forma:SolidPeso molecular:426.421Xevinapant hydrochloride
CAS:<p>Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide.</p>Fórmula:C32H44ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:598.19Esmolol hydrochloride
CAS:Esmolol is a cardioselective beta-blocker used in parenteral forms in the treatment of arrhythmias and severe hypertension.Fórmula:C16H25NO4·HClPureza:98.72% - 99.48%Cor e Forma:White SolidPeso molecular:331.15
