Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(9 produtos)
- BCL(11 produtos)
- Caspase(142 produtos)
- FOXO1(3 produtos)
- IAP(67 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(138 produtos)
- PDK(9 produtos)
- PERK(25 produtos)
- Serina/treonina quinase(14 produtos)
- Survivina(14 produtos)
- TNF(89 produtos)
- c-RET(56 produtos)
- p53(63 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5903 produtos de "Apoptose"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Dipin
CAS:Dipin is an Antineoplastic.Fórmula:C12H24N6O2P2Pureza:98%Cor e Forma:SolidPeso molecular:346.31PHA-690509
CAS:PHA-690509 is a cyclin-dependent kinase 2 inhibitor. It potentially for the treatment of cancer.Fórmula:C17H21N3O2SPureza:98%Cor e Forma:SolidPeso molecular:331.43Antitumor agent-83
Antitumor agent-83 activates BAX protein, impedes tumor growth, triggers apoptosis, and is stable in vitro.Fórmula:C29H30N6O2Cor e Forma:SolidPeso molecular:494.59Atopaxar
CAS:<p>Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.</p>Fórmula:C29H38FN3O5Pureza:97.07% - 98.07%Cor e Forma:SolidPeso molecular:527.63CAY10506
CAS:CAY10506, a hybrid lipoic acid-TZD, activates PPARγ to control glucose and lipid levels with an EC50 of 10 μM.Fórmula:C20H26N2O4S3Cor e Forma:SolidPeso molecular:454.63PhiKan 083 hydrochloride
CAS:PhiKan 083 HCl: carbazole, binds Y220C (Kd 167 μM), affinity in Ln229 (Kd 150 μM).Fórmula:C16H19ClN2Pureza:98%Cor e Forma:SolidPeso molecular:274.79Mutant p53 modulator-1
CAS:Mutant p53 modulator-1 inhibits cancer with p53 mutations; see patent WO2021231474A1, compound 231B.Fórmula:C27H32F4N8O2Cor e Forma:SolidPeso molecular:576.59FKGK 18
CAS:FKGK 18: GVIA iPLA2 inhibitor, 99.9% at 0.091 fraction, selective, IC50 ~50 nM–3 μM, reduces blood glucose and diabetes in NOD mice.Fórmula:C16H15F3OCor e Forma:SolidPeso molecular:280.28QM31
CAS:QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).Fórmula:C39H38Cl4N4O4Pureza:98%Cor e Forma:SolidPeso molecular:768.56RIP1 kinase inhibitor 6
CAS:<p>RIP1 Kinase Inhibitor 6 is a potent and selective inhibitor of RIP1 kinase, demonstrating inhibitory activity with an IC50 of less than 100 nM in a human R1P1</p>Fórmula:C19H18F2N2O3Pureza:98%Cor e Forma:SolidPeso molecular:360.35EGFR-IN-59
CAS:<p>EGFR-IN-59: EGFR inhibitor, IC50 = 190 nM, induces apoptosis, cytotoxic to A549 cells (IC50 = 8.62 μM) and WI38 cells (IC50 = 52.6 μM). Use: Various cancers.</p>Fórmula:C27H23N5O4SCor e Forma:SolidPeso molecular:513.57RET-IN-8
CAS:<p>RET-IN-8 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Fórmula:C27H30N6O3Cor e Forma:SolidPeso molecular:486.57Sanazole
CAS:Sanazole is a 3-nitrotriazole cpd. It can affect the human cervical cancer cell line.Fórmula:C7H11N5O4Cor e Forma:SolidPeso molecular:229.19DX2-201
CAS:DX2-201 is a potent and selective inhibitor of oxidative phosphorylation (OXPHOS) complex I (IC50: 312 nM) and exhibits anticancer activity.Fórmula:C18H28N2O6S2Cor e Forma:SolidPeso molecular:432.55SB-218078
CAS:SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM).Fórmula:C24H15N3O3Pureza:98%Cor e Forma:SolidPeso molecular:393.39EGFR-IN-46
CAS:EGFR-IN-46: Potent EGFR/FAK inhibitor (IC50: 20.17 & 14.25 nM), curbs cancer cell growth, triggers apoptosis.Fórmula:C27H32F3N3O3Cor e Forma:SolidPeso molecular:503.56Tubulin/HDAC-IN-1
CAS:Tubulin/HDAC-IN-1 is a dual inhibitor for tubulin & HDAC8, blocking polymerization & targeting HDAC8 (IC50: 150 nM), and induces cancer cell apoptosis.Fórmula:C21H18N4O3Cor e Forma:SolidPeso molecular:374.39PD-1/PD-L1-IN-14
CAS:<p>PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM).</p>Fórmula:C24H24N4O2Cor e Forma:SolidPeso molecular:400.47T-3256336
CAS:T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.Fórmula:C31H45F2N5O5Pureza:98%Cor e Forma:SolidPeso molecular:605.72BTK-IN-9
CAS:<p>BTK-IN-9 reversibly inhibits BTK, disrupts mitochondria, boosts ROS, and triggers apoptosis in Z138 cells, impeding condyloma cell growth.</p>Fórmula:C25H19N7O4Cor e Forma:SolidPeso molecular:481.46Pentabromophenol
CAS:<p>Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.</p>Fórmula:C6HBr5OPureza:99.83%Cor e Forma:Monoclinic Prisms From Acetic Acid; Needles From Alcohol Physical Description Light Brown Powder Insoluble In Water (Ntp 1992)Peso molecular:488.59RIPK1-IN-3
CAS:RIPK1-IN-3 is a RIPK1 inhibitor, with anti-inflammatory proprieties.Fórmula:C22H19F3N6O3Pureza:98%Cor e Forma:SolidPeso molecular:472.42Anti-inflammatory agent 11
CAS:Potent anti-inflammatory compound 16 combats tuberculosis, inhibiting Mtb H37Rv and M299 (MICs: 1.3, 6.9 μM) and reduces NO, TNF-α, IL-1β production.Fórmula:C14H14N4OSCor e Forma:SolidPeso molecular:286.35DCP-LA
CAS:DCP-LA (FR236924), linoleic acid derivatives, selective and direct activation of PKCε.Fórmula:C20H36O2Pureza:98%Cor e Forma:SolidPeso molecular:308.5MCL-1/BCL-2-IN-4
CAS:<p>MCL-1/BCL-2-IN-4 is a selective and potent Mcl-1 and Bcl-2 dual inhibitor.</p>Fórmula:C26H23BrN2O5SPureza:98%Cor e Forma:SolidPeso molecular:555.44EL-102
CAS:EL-102 is a HIF1α inhibitor with anticancer activity that inhibits microtubule protein polymerization and can be used to study prostate cancer.Fórmula:C19H16N2O3S2Pureza:99.34%Cor e Forma:SolidPeso molecular:384.47Irbesartan HCl
CAS:Irbesartan: angiotensin II blocker; treats hypertension by inhibiting receptor binding.Fórmula:C25H29ClN6OPureza:98%Cor e Forma:SolidPeso molecular:465(E)-[6]-Dehydroparadol
CAS:<p>(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.</p>Fórmula:C17H24O3Pureza:99.85%Cor e Forma:SolidPeso molecular:276.37K-7174 dihydrochloride
CAS:<p>K-7174 dihydrochloride is a novel cell adhesion inhibitor; inhibits the expression of vascular cell adhesion molecule-1 (VCAM-1) induced by either IL-1β or TNF-</p>Fórmula:C33H50Cl2N2O6Pureza:99.15%Cor e Forma:SolidPeso molecular:641.67PARP14 inhibitor H10
CAS:PARP14 inhibitor H10 is a selective inhibitor against PARP14 with IC50 of 490 nMFórmula:C24H27N7O7SPureza:98%Cor e Forma:SolidPeso molecular:557.58DJ001
CAS:<p>DJ001: specific PTPσ inhibitor, non-competitive, IC50=1.43 μM, aids hematopoietic stem cell regeneration.</p>Fórmula:C15H12N2O3Pureza:99.54%Cor e Forma:SolidPeso molecular:268.27CDK8/19-IN-1
CAS:CDK8/19-IN-1 is a selective and oral bioavailable CDK8/19 dual inhibitor (IC50s: 0.46 nM, 0.99 nM, and 270 nM for CDK8, CDK19, and CDK9).Fórmula:C19H18N4O4S2Pureza:98%Cor e Forma:SolidPeso molecular:430.5Psammaplysene A
CAS:Psammaplysene A is a FOXO1a nuclear export inhibitor.Fórmula:C27H35Br4N3O3Pureza:98%Cor e Forma:SolidPeso molecular:769.2W146 TFA
CAS:W146 TFA is a selective sphingosine-1-phosphate receptor 1 ( S1PR1 ) antagonist with an EC 50 value of 398 nM.Fórmula:C18H28F3N2O6PCor e Forma:SolidPeso molecular:456.399MYRA-A
CAS:MYRA-A is an inducer of apoptosis in a Myc-dependent manner that acts by inhibiting Myc-driven transformation and disrupting MYC-Max interaction.Fórmula:C19H20N2O4Pureza:98%Cor e Forma:SolidPeso molecular:340.37Epirubicin
CAS:Epirubicin, a doxorubicin derivative, is an antineoplastic, inhibits topoisomerase, DNA/RNA synthesis, and Foxp3, reducing T cell activity.Fórmula:C27H29NO11Cor e Forma:SolidPeso molecular:543.52SLMP53-2
CAS:SLMP53-2 is a mutant p53 reactivator that restores the wild-type-like conformation and DNA-binding ability of mutp53-Y220C through enhanced interaction withFórmula:C26H22N2O2Cor e Forma:SolidPeso molecular:394.47pan-HER-IN-1
CAS:<p>Compound C5: Irreversible, oral pan-HER inhibitor with low IC50s for EGFR/HERs; induces apoptosis and has antitumor effects.</p>Fórmula:C19H14BrN5OCor e Forma:SolidPeso molecular:408.25MpsBAY2a
CAS:carcinoma cell proliferation.Fórmula:C29H28N6OPureza:98%Cor e Forma:SolidPeso molecular:476.57TH1834 dihydrochloride
CAS:TH1834 dihydrochloride is a specific Tip60 histone acetyltransferase inhibitor.Fórmula:C33H42Cl2N6O3Pureza:98%Cor e Forma:SolidPeso molecular:641.63MBM-17
CAS:MBM-17 is a potent inhibitor of NIMA-related kinase 2 (Nek2,IC50 of 3 nM).Fórmula:C28H28N6O2Pureza:98%Cor e Forma:SolidPeso molecular:480.56NSC405640
CAS:NSC405640 selectively inhibits MDM2-p53 interaction, restoring mutated p53 structure; halts growth of cells with normal p53. [1]Fórmula:C12H10Cl2SnCor e Forma:SolidPeso molecular:343.82ML132
CAS:ML132 is an effective and selective inhibitor of caspase 1 (IC50: 0.316 nM).Fórmula:C22H28ClN5O5Cor e Forma:SolidPeso molecular:477.94KY1022
CAS:<p>KY1022 is a ras destabilizer. KY1022 targets the Wnt/ß-catenin pathway and inhibits development of metastatic colorectal cancer.</p>Fórmula:C17H19N3OSCor e Forma:SolidPeso molecular:313.42HL271
CAS:HL271, a derivative of metformin, is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment.Fórmula:C13H17ClF3N5OPureza:98%Cor e Forma:SolidPeso molecular:351.76Topoisomerase IIα-IN-3
CAS:<p>Topoisomerase IIα-IN-3 is a DNA-inserting topoisomerase-Iiα inhibitor that blocks the cell cycle in G0/G1 phase and induces apoptosis.</p>Fórmula:C29H20N6O2SCor e Forma:SolidPeso molecular:516.57EGFR-IN-56
CAS:EGFR-IN-56 (13a) inhibits EGFR, EGFRT790M (IC50: 541.7nM), EGFRT790M/L858R (IC50: 132.1nM), blocks G2/M phase, and triggers apoptosis.Fórmula:C23H22N4O3SCor e Forma:SolidPeso molecular:434.51Adapalene sodium salt
CAS:<p>Adapalene (CD 271; Differin) sodium salt is a synthetic retinoid and a Retinoic acid receptor agonist.</p>Fórmula:C28H28NaO3Pureza:98%Cor e Forma:SolidPeso molecular:435.519CDK1/2/4-IN-1
CAS:CDK1/2/4-IN-1 inhibits CDKs (IC50: CDK1-1.47μM; CDK2-0.78μM; CDK4-0.87μM) and is useful in cancer studies, affecting apoptosis and the cell cycle.Fórmula:C15H16N2O2SCor e Forma:SolidPeso molecular:288.36ACA-28
CAS:<p>ACA-28 is an ERK MAPK signalling modulator that induces apoptosis in melanoma cells by overexpressing ERK.</p>Fórmula:C17H16O6Pureza:98.73%Cor e Forma:SolidPeso molecular:316.31
![(E)-[6]-Dehydroparadol](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT13436.webp&w=3840&q=75)
