Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(127 produtos)
- FOXO1(3 produtos)
- IAP(65 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(24 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(91 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5622 produtos de "Apoptose"
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(S)-PERK-IN-5
CAS:<p>(S)-PERK-IN-5 is the S-enantiomer of PERK-IN-5. (S)-PERK-IN-5 is a PERK inhibitor (IC50: 0.101-0.250 μM).</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5Se-Methylselenocysteine hydrochloride
CAS:<p>Se-Methylselenocysteine hydrochloride, a precursor to Methylselenol, exhibits significant cancer chemopreventive and antioxidant activities.</p>Fórmula:C4H10ClNO2SePureza:98%Cor e Forma:SolidPeso molecular:218.54Erbstatin
CAS:<p>Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.</p>Fórmula:C9H9NO3Cor e Forma:SolidPeso molecular:179.17BI-0282
CAS:<p>BI-0282 (Compound 1) is a potent inhibitor of the MDM2-p53 interaction.</p>Fórmula:C30H23Cl2FN4O4Cor e Forma:SolidPeso molecular:593.43PI3K/Akt/mTOR-IN-3
CAS:<p>PI3K/Akt/mTOR-IN-3 is a powerful inhibitor, halting MCF-7, HeLa, and HepG2 cell migration and triggering S phase arrest and apoptosis.</p>Fórmula:C34H51NO2Cor e Forma:SolidPeso molecular:505.77Anticancer agent 83
CAS:<p>Anticancer agent 83: potent, GI50 0.15 mM against LOX IMVI, reduces mitochondria potential, DNA damage, induces leukemia apoptosis.</p>Fórmula:C20H19N5OSCor e Forma:SolidPeso molecular:377.46TJ08
CAS:<p>TJ08 has anticancer properties and can effectively induce G1/S phase blockade while promoting apoptosis in a variety of cancer cells.</p>Fórmula:C22H16FN3O4Pureza:99.89%Cor e Forma:SolidPeso molecular:405.38EP12
CAS:<p>EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by</p>Fórmula:C26H22FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:427.47Telomerase-IN-4
CAS:<p>Telomerase-IN-4 is a potent inhibitor of telomerase with antiproliferative properties and induces apoptosis [1].</p>Fórmula:C21H18N4OS2Pureza:98%Cor e Forma:SolidPeso molecular:406.52Anticancer agent 147
CAS:<p>Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS</p>Fórmula:C32H40BrN3O2Pureza:98%Cor e Forma:SolidPeso molecular:578.58c-Met-IN-14
CAS:<p>c-Met-IN-14: selective c-Met kinase inhibitor, IC50 2.89 nM, anticancer, stops G2/M phase, induces A549 cell apoptosis.</p>Fórmula:C34H38ClFN4O7SCor e Forma:SolidPeso molecular:701.2LLP-3
CAS:<p>Survivin inhibitor LLP-3 induces apoptosis in glioma cells by blocking Ran interaction; halts glioblastoma growth. IC50 = 31 μM.</p>Fórmula:C32H23ClN2O4Cor e Forma:SolidPeso molecular:534.99Antioxidant agent-5
CAS:<p>Antioxidant agent-5 (D-6) curbs oxLDL effects, ROS, NF-κB movement, apoptosis in VECs; boosts Nrf2/HO-1; protects endothelium.</p>Fórmula:C24H24N6OCor e Forma:SolidPeso molecular:412.49IDO1/TDO-IN-1
CAS:<p>IDO1/TDO-IN-1 (30) inhibits IDO1 (Ki=0.23μM) & TDO (Ki=0.73μM); induces apoptosis via Bcl-2/Bax.</p>Fórmula:C21H16O6Cor e Forma:SolidPeso molecular:364.35DBIBB
CAS:<p>DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.</p>Fórmula:C23H20N2O6SPureza:98.49% - 99.1%Cor e Forma:SolidPeso molecular:452.48Anticancer agent 72
CAS:<p>Compound 8c inhibits K+ channel and induces apoptosis, showing promise as an anticancer agent.</p>Fórmula:C20H19N7O2Cor e Forma:SolidPeso molecular:389.41NSC114792
CAS:<p>NSC114792 is a selective JAK3 inhibitor.</p>Fórmula:C26H32N4O2SPureza:98%Cor e Forma:SolidPeso molecular:464.62TACC3 inhibitor 1
<p>Potent TACC3 inhibitor 1 crosses the blood-brain barrier, induces apoptosis, G2/M arrest, ROS, and has anti-tumor effects.</p>Fórmula:C20H21N5OSCor e Forma:SolidPeso molecular:379.48GGTI-2154
CAS:<p>GGTI-2154 is a potent, selective geranylgeranyltransferase I (GGTase I) inhibitor, boasting an IC50 of 21 nM and demonstrating over 200-fold selectivity against</p>Fórmula:C24H28N4O3Cor e Forma:SolidPeso molecular:420.5Bcl-2/Mcl-1-IN-3
CAS:<p>Bcl-2/Mcl-1-IN-3 is a Bcl-2/Mcl-1 inhibitor that acts on Mcl-1 (Ki: 0.14 μM) and Bcl-2 (Ki: 0.23 μM) and can be used in cancer research.</p>Fórmula:C27H26ClNO4Cor e Forma:SolidPeso molecular:463.95Berubicin HCl
CAS:<p>Berubicin hydrochloride, a brain-penetrating anthracycline, disrupts DNA replication and repair by inhibiting topoisomerase II.</p>Fórmula:C34H36ClNO11Cor e Forma:SolidPeso molecular:670.1HIOC
CAS:<p>TrkB agonist; shields neurons & retinas; crosses blood-brain & retinal barriers.</p>Fórmula:C16H19N3O3Cor e Forma:SolidPeso molecular:301.34AQX-016A
CAS:<p>AQX-016A, a potent SHIP1 agonist, is an oral analog of pelorol, 3x stronger, inhibits PI3K, TNFa, for inflammation research.</p>Fórmula:C22H32O2Cor e Forma:SolidPeso molecular:328.49RET-IN-15
CAS:<p>RET-IN-15 is an inhibitor of rearrangement kinase (RET) during transfection and can be used in cancer research.</p>Fórmula:C27H28N8O2Cor e Forma:SolidPeso molecular:496.56Anticancer agent 71
CAS:<p>Compound 4b, a potent anticancer, halts G2/M cell cycle, triggers apoptosis, alters Bax, Ikb-α, PARP, and Bcl-2 levels.</p>Fórmula:C18H13ClF3N5OCor e Forma:SolidPeso molecular:407.78PERK-IN-5
CAS:<p>PERK-IN-5: oral PERK inhibitor, IC50 of 2 nM; blocks p-eIF2α at 9 nM; hinders tumor growth in renal cancer model.</p>Fórmula:C25H26F2N4O3Cor e Forma:SolidPeso molecular:468.5CX-5011
CAS:<p>CX-5011, a CK2 inhibitor, induces Rac1 activation and promotes apoptosis, effectively causing cancer cell death [1] [2].</p>Fórmula:C20H12N4O2Pureza:98%Cor e Forma:SolidPeso molecular:340.33NBI-42902
CAS:<p>NBI-42902 is a potent GnRH receptor antagonist (Ki=0.56 nm, Kd=0.19 nm), suppressing serum LH in macaques without causing histamine release.</p>Fórmula:C27H24F3N3O3Cor e Forma:SolidPeso molecular:495.49PI3K-IN-34
CAS:<p>PI3K-IN-34 targets PI3K-α/β/δ (IC50: 11.73/6.09/11.18 μM); potential leukemia research tool.</p>Fórmula:C23H22N6O3Cor e Forma:SolidPeso molecular:430.46hGGPPS-IN-1
CAS:<p>HGGPPS-IN-1: analog of C2-ThP-BPs, inhibits hGGPPS, triggers apoptosis in MM cells, shows anti-myeloma effects in vivo.</p>Fórmula:C13H13N3O6P2SCor e Forma:SolidPeso molecular:401.27IW-927
CAS:<p>IW-927 is a potent and selective TNFα/TNFRc1 interaction antagonist.</p>Fórmula:C22H23N3O3S2Cor e Forma:SolidPeso molecular:441.57Thioxodihydroquinazolinone-19
CAS:<p>Thioxodihydroquinazolinone-19 triggers apoptosis in A2780cis ovarian cancer cells and enhances cisplatin efficacy.</p>Fórmula:C16H14N2OSPureza:98%Cor e Forma:SolidPeso molecular:282.36Anticancer agent 99
CAS:<p>Anticancer agent 99 targets HepG2 cells, IC50 at 35.9 μM, induces apoptosis and hinders cell growth.</p>Fórmula:C19H20F3N3O2Cor e Forma:SolidPeso molecular:379.38EGFR/HER2/TS-IN-1
CAS:<p>EGFR/HER2/TS-IN-1 inhibits EGFR (0.203 μM), HER2 (0.088 μM), TS (0.168 μM), and induces apoptosis in MCF7 cells.</p>Fórmula:C24H15N5O4S2Cor e Forma:SolidPeso molecular:501.54Bcl-2/Mcl-1-IN-1
CAS:<p>Bcl-2/Mcl-1-IN-1 is an inhibitor of Bcl-2 (Ki: 4.53 μM) and Mcl-1 (Ki: 1.19 μM).Bcl-2/Mcl-1-IN-1 can be used in cancer research.</p>Fórmula:C28H23NO3Cor e Forma:SolidPeso molecular:421.49Verticillin A
CAS:<p>Verticillin A, an apoptosis inducer, inhibits Leiomyosarcoma and Malignant peripheral nerve sheath tumor growth.</p>Fórmula:C30H28N6O6S4Pureza:98%Cor e Forma:SolidPeso molecular:696.84SK-7041
CAS:<p>SK-7041 is an effective HDAC inhibitor that acts by preferentially inhibiting class I HDAC1 and HDAC2.</p>Fórmula:C19H21N3O3Pureza:98%Cor e Forma:SolidPeso molecular:339.39p-DDAP
CAS:<p>p-DDAP inhibits cell invasion and reduces MMP-9 activity and expression.</p>Fórmula:C18H31NOPureza:98%Cor e Forma:SolidPeso molecular:277.44HDAC6-IN-4
CAS:<p>HDAC6-IN-4 (C10), an oral, selective, potent HDAC6 inhibitor with low toxicity, IC50: 23 nM, promotes apoptosis and strong anti-tumor action.</p>Fórmula:C30H38N2O5Cor e Forma:SolidPeso molecular:506.63VEGFR-2/BRAF-IN-2
<p>VEGFR-2/BRAF-IN-2 inhibits VEGFR-2, BRAF V600E, BRAF WT (IC50: 0.111/0.089/0.071 µM); induces G1 arrest and apoptosis.</p>Fórmula:C26H21ClF3N5O3S2Cor e Forma:SolidPeso molecular:608.05CDK9-IN-18
CAS:<p>CDK9-IN-18: Potent CDK9 blocker, anticancer, induces apoptosis, low cellular activity.</p>Fórmula:C27H20N8OCor e Forma:SolidPeso molecular:472.5CCT128930
CAS:<p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>Fórmula:C18H20ClN5Pureza:99.07% - 99.18%Cor e Forma:SolidPeso molecular:341.84MMP-9-IN-5
CAS:<p>MMP-9-IN-5: MMP-9 and AKT inhibitor (IC50: 4.49 nM and 1.34 nM), induces apoptosis for cancer research.</p>Fórmula:C27H20IN3O4Cor e Forma:SolidPeso molecular:577.37PSB 0474
CAS:<p>P2Y6 receptor agonist</p>Fórmula:C17H20N2O13P2Pureza:98%Cor e Forma:SolidPeso molecular:522.29MEK-IN-5
CAS:<p>MEK-IN-5: strong MEK inhibitor and NO donor, reduces pMEK/pERK dose/time-dependently, triggers apoptosis in MDA-MB-231 cells.</p>Fórmula:C29H27FN4O10S2Cor e Forma:SolidPeso molecular:674.67YLT-11
<p>YLT-11: Oral PLK4 inhibitor, Kd 5.2 nM; less effective on PLK1/2/3; inhibits cancer cell growth and induces G2/M arrest and apoptosis.</p>Fórmula:C24H24N6OCor e Forma:SolidPeso molecular:412.49Anticancer agent 67
CAS:<p>Anticancer agent 67 is a ciprofloxacin analogue, an anticancer agent that induces apoptosis and increases sub-G1 cell populations in MCF-7 cells.</p>Fórmula:C26H24F2N6O2S2Cor e Forma:SolidPeso molecular:554.63Quinidine Monosulfate
CAS:<p>Quinidine Monosulfate: an oral antiarrhythmic, CYP450db inhibitor, K+ blocker (IC50 19.9 μM), used in malaria research.</p>Fórmula:C40H50N4O8SCor e Forma:SolidPeso molecular:746.92Tubulin polymerization-IN-13
CAS:<p>Compound 4f inhibits tubulin polymerization (IC50: 0.37 μM), induces apoptosis, and has notable anti-cancer properties.</p>Fórmula:C20H21NO6Cor e Forma:SolidPeso molecular:371.385HPP-33
CAS:5HPP-33 is an microtubule-stabilizer with the properties of antiproliferative and antimitotic.Fórmula:C20H21NO3Cor e Forma:SolidPeso molecular:323.39
