Apoptose
Os inibidores da apoptose são compostos que previnem ou retardam o processo de morte celular programada, conhecido como apoptose. Esses inibidores são vitais no estudo dos mecanismos de sobrevivência celular e são usados para investigar doenças onde a apoptose é desregulada, como câncer, distúrbios neurodegenerativos e doenças autoimunes. Ao modular a apoptose, esses inibidores podem ajudar no desenvolvimento de terapias destinadas a controlar a morte celular. Na CymitQuimica, oferecemos uma ampla seleção de inibidores da apoptose de alta qualidade para apoiar sua pesquisa em biologia celular, oncologia e áreas relacionadas.
Subcategorias de "Apoptose"
- ASK(6 produtos)
- BCL(11 produtos)
- Caspase(127 produtos)
- FOXO1(3 produtos)
- IAP(66 produtos)
- Mdm2(12 produtos)
- PD-1/PD-L1(126 produtos)
- PDK(9 produtos)
- PERK(23 produtos)
- Serina/treonina quinase(15 produtos)
- Survivina(13 produtos)
- TNF(91 produtos)
- c-RET(51 produtos)
- p53(62 produtos)
Exibir 6 mais subcategorias
Foram encontrados 5618 produtos de "Apoptose"
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CPI-7c
CAS:CPI-7c inhibits MDM2-p53 interaction and promotes MDM2 degradation.Fórmula:C22H18N2O3Pureza:98%Cor e Forma:SolidPeso molecular:358.39PI3Kδ-IN-10
CAS:<p>PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50= 2 nM).</p>Fórmula:C19H16ClN9Cor e Forma:SolidPeso molecular:405.84Anticancer agent 42
CAS:<p>Oral anticancer 42 targets MDA-MB-231 cells; IC50 0.07μM; triggers apoptosis, enhances p53. Useful for metastatic breast cancer study.</p>Fórmula:C19H16Cl2N2O3Cor e Forma:SolidPeso molecular:391.25CFM-5
CAS:<p>CFM-5 has anticonvulsant activity and is used in epilepsy research.</p>Fórmula:C23H18BrN3OSPureza:98%Cor e Forma:SolidPeso molecular:464.38RC-33 HCl
CAS:<p>RC-33 HCl is a selective and metabolically stable σ1 receptor agonist potentiating NGF-induced neurite outgrowth.</p>Fórmula:C21H28ClNPureza:98%Cor e Forma:SolidPeso molecular:329.91SMBA2
CAS:<p>SMBA2 is a Bax activator. It acts by specifically targeting the binding pocket at S184.</p>Fórmula:C8H16N4Pureza:98%Cor e Forma:SolidPeso molecular:168.24HLI 373
CAS:<p>HLI373: potent Hdm2 (ubiquitin ligase) inhibitor, induces apoptosis in tumor cells, has antimalarial properties.</p>Fórmula:C18H23N5O2Cor e Forma:SolidPeso molecular:341.41Undecylprodigiosin
CAS:<p>Undecylprodigiosin is a classical cytotoxic immunosuppressant, suppressing immune functions. It also inhibits DNA synthesis.</p>Fórmula:C25H35N3OCor e Forma:SolidPeso molecular:393.56Anticancer agent 57
CAS:<p>Anticancer agent 57 blocks TNBC cell growth with IC50: 6.43-8 μM, induces apoptosis, and shrinks tumors in mice.</p>Fórmula:C20H21Cl2NO2Cor e Forma:SolidPeso molecular:378.29Tolbutamide Sodium
CAS:potassium channel blockerFórmula:C12H18N2NaO3SPureza:98%Cor e Forma:SolidPeso molecular:293.34Mcl1-IN-11
CAS:<p>Mcl1-IN-11 (Compound G) is a selective Mcl-1 inhibitor, less potent at Bcl-2, with Kis of 0.06 and 4.2 μM, respectively.</p>Fórmula:C38H41N3O5S2Pureza:98%Cor e Forma:SolidPeso molecular:683.88AG311
CAS:<p>AG311 inhibits complex I; destabilizes HIF-1α; triggers necrosis in cancer cells, mitochondrial depolarization, superoxide, and calcium increase.</p>Fórmula:C17H15N5SCor e Forma:SolidPeso molecular:321.4Dimethoate
CAS:<p>Dimethoate (L-395) is a systemic and contact insecticide for control of cattle grubs and certain other insect pests of farm animals.</p>Fórmula:C5H12NO3PS2Pureza:99.74% - 99.91%Cor e Forma:White Crystalline SolidPeso molecular:229.26MPT0B002
CAS:MPT0B002 is a microtubule inhibitor that acts by downregulating T315I mutant Bcr-Abl and inducing apoptosis of imatinib-resistant chronic myeloid leukemia cellsFórmula:C19H19NO4Pureza:98%Cor e Forma:SolidPeso molecular:325.36BIBU-1361 dihydrochloride
CAS:<p>BIBU-1361 dihydrochloride inhibits EGFR kinase, blocking MAPKK/MAPK activation.</p>Fórmula:C22H29Cl3FN7Cor e Forma:SolidPeso molecular:516.87p53 Activator 3
CAS:<p>Potent p53 activator, SC150 <0.05 mM, restores mutant p53 DNA binding, exhibits anti-tumor properties.</p>Fórmula:C30H37F3N4O4SCor e Forma:SolidPeso molecular:606.7Caspase-9 Inhibitor III
CAS:<p>Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.</p>Fórmula:C24H35ClN6O9Cor e Forma:SolidPeso molecular:587.02Antiproliferative agent-11
<p>Antiproliferative agent-11, a Ruthenium(II) complex, targets multiple cancers with IC50s of 6-10 μM.</p>Fórmula:C31H34Cl2N6O3P2RuCor e Forma:SolidPeso molecular:772.56Norartocarpetin
CAS:<p>Norartocarpetin inhibits tyrosinase (IC50 0.47μM), prevents browning in food, and fights lung cancer (IC50 22μM) by disrupting cell mechanisms.</p>Fórmula:C15H10O6Cor e Forma:SolidPeso molecular:286.24PHM16
CAS:<p>PHM16 is an ATP competitive FAK and FGFR2 inhibitor.</p>Fórmula:C20H22N6O4Pureza:98%Cor e Forma:SolidPeso molecular:410.43Mcl-1 inhibitor 10
CAS:<p>Mcl-1 inhibitor10 (compound 43) is a relatively potent MCL-1 inhibitor with an IC50 of 0.67 μM. It interacts with a specific binding site on the MCL-1 protein, disrupting its pro-survival signals and inducing apoptosis in cancer cells. This compound is useful for research on MCL-1-dependent cancers.</p>Fórmula:C21H15F3O4Cor e Forma:SolidPeso molecular:388.34Quinidine polygalacturonate
CAS:Quinidine polygalacturonate: oral cytochrome P450db inhibitor, K+ channel blocker (IC50 19.9 μM), induces apoptosis, anti-arrhythmic, aids malaria research.Fórmula:C26H34N2O9Cor e Forma:SolidPeso molecular:518.22643Gemcitabine monophosphate
CAS:<p>R306465, a potent HDAC1/8 inhibitor, has broad antitumor effects (IC50: 30-300 nM) on solid and blood cancers.</p>Fórmula:C9H12F2N3O7PCor e Forma:SolidPeso molecular:343.18MeOIstPyrd
CAS:<p>MeOIstPyrd is an anti-skin cancer agent that inhibits cell proliferation, migration, and spheroid formation through activation of the mitochondrial intrinsic</p>Fórmula:C14H16N4O2SCor e Forma:SolidPeso molecular:304.37Antitumor agent-19
CAS:<p>Antitumor agent-19 is a modulator of tumor-associated macrophages with EC50s of 17.18 μM and 18.87 μM in the RAW 264.7 cells and the BMDM cells.</p>Fórmula:C24H21ClF3N5OPureza:98.95% - 99.38%Cor e Forma:SolidPeso molecular:487.9Jolkinolide B
CAS:<p>Jolkinolide B is a bioactive diterpene isolated from the roots of Euphorbia fischeriana Steud.</p>Fórmula:C20H26O4Pureza:99.39% - 99.7%Cor e Forma:SolidPeso molecular:330.42CN128 hydrochloride
CAS:<p>CN128 hydrochloride is an oral, selective hydroxypyridone iron chelator for β-thalassemia research.</p>Fórmula:C15H18ClNO3Cor e Forma:SolidPeso molecular:295.76Apoptosis inducer 8
CAS:<p>Apoptosis inducer 8 is a galectin-1 (gal-1)-mediated apoptosis inducer and a PET imaging agent that significantly reduces gal-1 protein levels and can be used</p>Fórmula:C29H22ClN5O2Cor e Forma:SolidPeso molecular:507.97MM-102
CAS:<p>MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay.Cost-effective and quality-assured.</p>Fórmula:C35H49F2N7O4Pureza:98.77% - 99.99%Cor e Forma:SolidPeso molecular:669.8PIK-C98
CAS:<p>PIK-C98 is an inhibitor of PI3K that acts by displaying potent preclinical activity against multiple myeloma.</p>Fórmula:C16H10Cl2N2OSPureza:98%Cor e Forma:SolidPeso molecular:349.23PDMP (hydrochloride)
CAS:<p>PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.</p>Fórmula:C23H39ClN2O3Cor e Forma:SolidPeso molecular:427.03CGP 65015
CAS:<p>CGP 65015 is an oral iron chelator and can mobilize iron deposits.</p>Fórmula:C14H15NO4Pureza:98%Cor e Forma:SolidPeso molecular:261.27STAT3-IN-10
CAS:<p>STAT3-IN-10 (A11) inhibits STAT3; halts tumor growth and triggers apoptosis in cancer cells (IC 50 = 5.18 μM).</p>Fórmula:C17H13NO5Cor e Forma:SolidPeso molecular:311.29Bcl-2-IN-9
CAS:<p>Bcl-2-IN-9: a novel, selective Bcl-2 inhibitor inducing apoptosis in leukemia with an IC50 of 2.9 μM; low cytotoxicity.</p>Fórmula:C27H31N7O3SCor e Forma:SolidPeso molecular:533.65Anti-inflammatory agent 15
CAS:<p>Compound 29, anti-inflammatory and antimycobacterial, halts Mtb H37Rv and M299 growth; MIC50 at 2.3 and 7.8 μM. Blocks iNOS, TNF-α, IL-1β.</p>Fórmula:C17H20N2SCor e Forma:SolidPeso molecular:284.42HDAC-IN-42
CAS:<p>HDAC-IN-42, a potent HDAC inhibitor: IC50 - 0.19μM (HDAC1), 4.98μM (HDAC6); halts cancer cell growth, triggers apoptosis & G2/M arrest.</p>Fórmula:C20H15NO7Cor e Forma:SolidPeso molecular:381.34HS56
CAS:<p>HS56: ATP-competitive Pim/DAPK3 inhibitor, Ki: DAPK3 (0.26μM), Pim-3 (0.208μM), Pim-1 (2.94μM), Pim-2 (>100μM), reduces hypertension in mice.</p>Fórmula:C13H8ClN5OSCor e Forma:SolidPeso molecular:317.75CA224
CAS:<p>CA224: selective oral Cdk4-cyclin D1 inhibitor, IC50=6.2μM, promotes apoptosis, has antitumor effects.</p>Fórmula:C24H22N2OCor e Forma:SolidPeso molecular:354.44Mps1-IN-5
CAS:<p>Mps1-IN-5: oral Mps1 inhibitor with 29 nM IC50, induces apoptosis, G2/M arrest, and has anti-tumor properties.</p>Fórmula:C24H25N9Cor e Forma:SolidPeso molecular:439.52GK563
CAS:<p>GK563, an iPLA2 inhibitor (IC50=1nM), is 22,000x more potent vs. cPLA2 and may reduce β-cell death in type 1 diabetes.</p>Fórmula:C16H22O2Cor e Forma:SolidPeso molecular:246.34Caspase-3/7 activator 2
<p>Caspase-3/7 activator 2 triggers apoptosis with tumor selectivity and anti-proliferative properties.</p>Fórmula:C32H34N2O7Cor e Forma:SolidPeso molecular:558.62PD-1/PD-L1-IN 6
CAS:<p>Compound A13 inhibits PD-1/PD-L1, enhances interferon-γ, lacks toxicity, and boosts immune response in co-culture models. IC50=132.8 nM.</p>Fórmula:C25H26N2O3Cor e Forma:SolidPeso molecular:402.49CB-64D
CAS:<p>CB-64D is a sigma2R selective agonist which releases calcium in human neuroblastoma cells and produces cell death in tumor cell lines.</p>Fórmula:C22H23NO2Cor e Forma:SolidPeso molecular:333.42Antiproliferative agent-19
Antiproliferative agent-19 induces apoptosis and G2/M cell cycle arrest in lung cancer cells.Fórmula:C26H23NOCor e Forma:SolidPeso molecular:365.47(R)-STU104
CAS:(R)-STU104 is a TAK1-MKK3 protein-protein interaction (PPI) inhibitor. (R)-STU104 is a candidate compound for the treatment of ulcerative colitis.Fórmula:C18H18O4Pureza:98.91% - 99.42%Cor e Forma:SolidPeso molecular:298.33Anticancer agent 47
CAS:<p>Compound 4j: potent anticancer agent; halts cell growth, induces apoptosis and G0/G1 arrest; significant in vivo tumor reduction.</p>Fórmula:C19H14N2O4SCor e Forma:SolidPeso molecular:366.39Bisindolylmaleimide VIII
CAS:<p>Bisindolylmaleimide VIII (Ro-31-7549) is a selective and highly potent protein kinase C (PKC) inhibitor.</p>Fórmula:C24H22N4O2Pureza:97% - 98.01%Cor e Forma:SolidPeso molecular:398.46PBENZ-DBRMD
CAS:<p>PBENZ-DBRMD inhibits DIO3, has anti-growth effects, and aids apoptosis, showing promise for cancer research.</p>Fórmula:C11H5Br2NO4Cor e Forma:SolidPeso molecular:374.97Telomerase-IN-5
CAS:<p>Telomerase-IN-5 is a potent inhibitor of telomerase with antiproliferative properties, and it induces apoptosis [1].</p>Fórmula:C22H20N4OS2Pureza:98%Cor e Forma:SolidPeso molecular:420.55NSC 146109 hydrochloride
CAS:<p>NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.</p>Fórmula:C17H17ClN2SPureza:99.28%Cor e Forma:SolidPeso molecular:316.85
